Chromosome Rearrangement Breakpoint Clustering: The Role of Clonal Selection
ON Umanskaya, AA Bystritskiy, SV Razin - MOLECULAR BIOLOGY, 2005 - springerlink.com
... Like MLL, AML1 also codes for a transcription factor, with breakpoints also clus-
CDX2 STL MN1 EVI1 AML1 FGFR3 BTL ABL BCR JAK2 ARNT ACS2 ARG PAX5 ...
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A Novel Cryptic Translocation t (12; 17)(p13; p12–p13) in a Secondary Acute Myeloid Leukemia …
E MN - GENES, CHROMOSOMES & CANCER, 2003 - doi.wiley.com
... Fusion of ETV6 to MDS1/EVI1 as result of t(3;12)(q26;p13) in ... t(1;12)(q21; p13)
translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion. ...
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A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... IRF2 01 Interferon regulatory factor 2 Core should be AAGYGAAA not GAAA EVI1 06
Ectopic viral integration site 1 encoded factor Core should be ACAAGAT not AGAT ...
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Identification of new translocations involving ETV 6 in hematologic malignancies by fluorescence in …
MD Odero, K Carlson, MJ Calasanz, I Lahortiga, V … - Genes Chromosomes and Cancer, 2001 - doi.wiley.com
... chromo- some bands have been shown to be involved in ETV6 translocations, of which
13 have been cloned: ARNT (1q21), ARG (1q25), MDS1/EVI1 (3q26), CHIC2/BTL ...
Cited by 19 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Fusion of ETV6 to fibroblast growth factor receptor 3 in peripheral T-cell lymphoma with at (4; 12)( … - Full text - MIT Libraries
F Yagasaki, D Wakao, Y Yokoyama, Y Uchida, I … - Cancer Res, 2001 - cancerres.aacrjournals.org
... to fuse to a number of different partner genes such as MDS1/EVI1(3q26) (3 ... 12) ,
AML1(21q22) (13 , 14) , MN1(22q11) (15) , ARG(1q25) (16 , 17) , ARNT(1q21) (18 ...
Cited by 12 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Fusion of the TEL Gene on 12p13 to the AML1 Gene on 21q22 in Acute Lymphoblastic Leukemia - Full text - MIT Libraries
TR Golub, GF Barker, SK Bohlander, SW Hiebert, DC … - Proceedings of the National Academy of Sciences, 1995 - pnas.org
... p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion
PNAS ... GM Cuenco, G. Nucifora, and R. Ren Human AML1/MDS1/EVI1 fusion protein ...
Cited by 349 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

G ENETIC P ROFILE OF A CUTE M YELOID L EUKEMIA - Full text - MIT Libraries
C Mecucci, R Rosati, R La Starza - Reviews in Clinical & Experimental Hematology, 2002 - blackwell-synergy.com
... of ETV6 and almost all the aryl hydrocarbon receptor nuclear translocator (ARNT)
protein. ... ETV6 drives the expression of the partner genes, ie MDS1/EVI1 in the t ...
Cited by 4 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Evidence for position effects as a variant ETV6-mediated leukemogenic mechanism in myeloid leukemias … - Full text - MIT Libraries
J Cools, N Mentens, MD Odero, P Peeters, I … - Blood, 2002 - bloodjournal.org
... of the activity of the transcription factors such as CBFA2 and ARNT or the ... 18 Finally,
the ETV6-MDS1/EVI1 and ETV6-CDX2 fusions only contain the transcription ...
Cited by 13 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Molecular pathogenesis of MDS
H Hirai - Int J Hematol, 2002 - haem.nus.edu.sg
... TEL gene is also fused to ARNT, MN1, EVI-1 and ACS2 in MDS cases carrying t(1;12)
(q21;p13), t(12;22)(p13;q11), t(3;12)(q26;p13) and t(5;12) (q31;p13 ...
Cited by 3 - View as HTML - Web Search - ishapd.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

TEL/ETV6 GENE REARRANGEMENTS IN HUMAN LEUKEMIAS
EMA ANASTASIADOU, MH TOMASSON, DW STERNBERG, TR … - doi.wiley.com
... translo- cations is an active promoter, as in the TEL/ EVI1 fusions (Peeters ... ACS2
gene) and the aryl hydrocarbon receptor nuclear transporter (ARNT), which is ...
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Molecular Mechanisms of Myelodysplastic Syndrome - Full text - MIT Libraries
H Hirai - Japanese Journal of Clinical Oncology, 2003 - jjco.oupjournals.org
... translocation of human acute myeloblastic leukemia results in a TEL–ARNT fusion. ...
at 3q21 associated with the transcriptional activation of the EVI1 gene in ...
Cited by 5 - Web Search - jjco.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL - Full text - MIT Libraries
LC Wang, F Kuo, Y Fujiwara, DG Gilliland, TR Golub … - The EMBO Journal, 1997 - embojournal.npgjournals.com
... 1 (Golub et al., 1995; Romana et al., 1995a ), EVI1 (Raynaud et al ... Carmeliet et al.,
1996b); and arylhydrocarbon receptor nuclear translocator, ARNT (Maltepe et ...
Cited by 94 - Web Search - nature.com - emboj.org - ncbi.nlm.nih.gov - all 6 versions »

Analysis of the interaction of TIP60β and PIN1 with the ets family transcription factor ETV6
CD Zhang - edoc.ub.uni-muenchen.de
... and FGFR3, to transcription factors, such as AML1/RUNX1, EVI1, HLXB9, MN1 or PAX5,
to genes of various or unknown functions, such as STL, BTL, ARNT, MDS2, TTL ...
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A Novel Gene, MDS2, Is Fused to ETV6/TEL in a t (1; 12)(p36. 1; p13) in a Patient With …
MD Odero, JL Vizmanos, JP Roman, I Lahortiga, C … - Genes Chromosomes Cancer, 2002 - doi.wiley.com
... to be involved in ETV6 translocations (reviewed in Odero et al., 2001), and 16 partner
genes have been cloned: ARNT (1q21), ARG (1q25), MDS1/EVI1 (3q26), CHIC2 ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... genes, 411—412 t(8;21) translocation, 409—411 AML1/MDS1/EVI1 fusion protein ... 335—336
AP1 protein, PML-RAR fusion protein and, 338 ARNT transporter, TEL ...
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[CITATION] Anomalies chromosomiques dans les leucemies aigues myeloides
F Mugneret, P Callier, B Favre-Audry
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Leukemic kinases of the Abl family− an update
J Voss, N Heisterkamp, J Groffen, SM Feller - Signal Transduction, 2001 - doi.wiley.com
... CBF α t(12;21)(p13;q22) ARNT aryl hydrocarbon t(1;12)(q21;p13) AML-M2 [267] ...
MDS1/EVI1 transcription factor t(3;12)(q26;p13) MDS [273] ...
Cited by 4 - Web Search

Characterization of the recurrent translocation t (1; 1)(p 36. 3; q 21. 1-2) in non-Hodgkin lymphoma …
VS Lestou, O Ludkovski, JM Connors, RD Gascoyne, … - Genes Chromosomes and Cancer, 2003 - doi.wiley.com
... gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and ... p13)
translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion ...
Cited by 7 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries