Cooperative interaction between AhR. Arnt and Sp1 for the drug-inducible expression of CYP1A1 gene - Full text - MIT Libraries
A Kobayashi, K Sogawa, Y Fujii-Kuriyama - J. Biol. Chem, 1996 - jbc.org
... Biochemistry and Molecular Biology, Inc. Cooperative Interaction between AhR
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Regulation of constitutive gene expression through interactions of Sp1 protein with the nuclear aryl … - Full text - MIT Libraries
F Wang, W Wang, S Safe - Biochemistry, 1999 - ncbi.nlm.nih.gov
... The functional interactions of Sp1 with AhR-Arnt were paralleled by physical
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Functional and physical interactions between the estrogen receptor Sp 1 and nuclear aryl hydrocarbon … - Full text - MIT Libraries
F Wang, D Hoivik, R Pollenz, S Safe - Nucleic Acids Research, 1998 - nar.oupjournals.org
... Figure 7. Co-immunoprecipitation of in vitro translated 35 S-labeled ER with AhR,
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Transcriptional activation of c-fos protooncogene by 17ss-estradiol: Mechanism of aryl hydrocarbon … - Full text - MIT Libraries
R Duan, W Porter, I Samudio, C Vyhlidal, M Kladde, … - Mol. Endocrinol, 1999 - mend.endojournals.org
... 2 ). ER but not AhR/Arnt enhanced Sp1-DNA binding (lanes 3 and 4), and in unlabeled
oligonucleotide competition studies (lanes 6–8), Sp1 but not mutant Sp1 ...
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Dioxin induces localized, graded changes in chromatin structure: implications for Cyp1A1 gene … - Full text - MIT Libraries
ST Okino, JP Whitlock Jr - Mol. Cell. Biol, 1995 - mcb.asm.org
... DNA interactions on the Cyp1A1 enhancer; LMPCR analysis with primer set B. Binding
sites for AhR/Arnt, Sp1, and the G-box- binding protein (GBP) are indicated. ...
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Critical Enhancer Region to Which AhR/ARNT and Sp 1 Bind in the Human CYP 1 B 1 Gene - Full text - MIT Libraries
Y Tsuchiya, M Nakajima, T Yokoi - Journal of Biochemistry, 2003 - jb.oupjournals.org
... MOLECULAR BIOLOGY. Critical Enhancer Region to Which AhR/ARNT and Sp1 Bind in the
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Proteasome inhibition induces nuclear translocation of the dioxin receptor through an Sp1 and … - Full text - MIT Libraries
B Santiago-Josefat, PM Fernandez-Salguero - J Mol Biol, 2003 - ncbi.nlm.nih.gov
... These data suggest that cellular control of protein kinase C activity, through Sp1
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Histone deacetylase 1 can repress transcription by binding to Sp1 - Full text - MIT Libraries
A Doetzlhofer, H Rotheneder, G Lagger, M Koranda, … - Mol. Cell. Biol, 1999 - mcb.asm.org
... Kuriyama. 1996. Cooperative interaction between AhR.Arnt and Sp1 for the
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Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel … - Full text - MIT Libraries
R URRUTIA - Biochem. J, 2002 - biochemj.org
... nuclear translocator (Arnt) transcriptional acti- vators [6]. In addition, deletion
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A novel positive regulatory element that enhances hamster CYP2A8 gene expression mediated by … - Full text - MIT Libraries
K Kurose, M Tohkin, M Fukuhara - Mol Pharmacol, 1999 - molpharm.org
... Cooperative Transcriptional Enhancement of AhR-Arnt with Sp1. We ... Arnt and
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The aryl hydrocarbon receptor interacts with transcription factor IIB - Full text - MIT Libraries
HI Swanson, JH Yang - Mol. Pharmacol, 1998 - molpharm.aspetjournals.org
... Kobayashi A, Sogawa K and Fujii-Kuriyama Y (1996) Cooperative interaction between
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17 beta-Estradiol hydroxylation catalyzed by human cytochrome P450 1B1 - Full text - MIT Libraries
CL Hayes, DC Spink, BC Spink, JQ Cao, NJ Walker, … - Carcinogenesis, 2004 - dx.doi.org
... Home page Y. Tsuchiya, M. Nakajima, and T. Yokoi Critical Enhancer Region to Which
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Interaction between Dioxin Signaling and Sex Steroid Hormones - Full text - MIT Libraries
H Sone, J Yonemoto - Journal of Health Science, 2002 - jhs.pharm.or.jp
... 28) Kobayashi, A., Sogawa, K. and Fujii-Kuriyama, Y. (1996) Cooperative interaction
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An autoregulatory loop controlling CYP1A1 gene expression: role of H 2 O 2 and NFI - Full text - MIT Libraries
Y Morel, N Mermod, R Barouki - Mol Cell Biol, 1999 - mcb.asm.org
... Kuriyama. 1996. Cooperative interaction between AhR.Arnt and Sp1 for the
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[CITATION] Cooperative Interaction between AhR bullet Arnt and Sp1 for the Drug-inducible Expression...
S In, PST Access, S Up
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Functional Analysis of BTEB3 and BTEB4, a novel Sp1-like protein, Reveal a Subfamily of …
JA Kaczynski, AA Conley, MF Zapico, SM Delgado - biochemj.org
... Interaction between ArH-Arnt and Sp1 for the Drug-inducible Expresion of
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Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor … - Full text - MIT Libraries
R Muangmoonchai, D Smirlis, SC Wong, M Edwards, IR … - Biochem J, 2001 - biochemj.org
... requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1 ... 2001
Biochemical Society Page 3. 73 CYP2B1 gene regulation by CAR, SRC-1 and Sp1 ...
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3-Methylcholanthrene Activates Human Immunodeficiency Virus Type 1 Replication via Aryl Hydrocarbon … - Full text - MIT Libraries
H Ohata, T Tetsuka, H Hayashi, K Onozaki, T … - Microbiol. Immunol, 2003 - sanbi.co.jp
... Cooperative interaction between AhR.Arnt and Sp1 for the drug-inducible
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Exposure of Mouse Preimplantation Embryos to 2, 3, 7, 8-Tetrachlorodibenzo-P-dioxin(TCDD) Alters the … - Full text - MIT Libraries
Q Wu, S Ohsako, R Ishimura, JS Suzuki, C Tohyama - Biology of Reproduction, 2004 - bioone.org
... preimplantation development [28] , and an in vitro transcription study using CYP1A1
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Biotin Supplementation Increases Expression of the Cytochrome P 450 1B1 Gene in Jurkat Cells, … - Full text - MIT Libraries
R Rodriguez-Melendez, JB Griffin, J Zempleni - J. Nutr, 2004 - nutrition.org
... 23. Tsuchiya, Y., Nakajima, M. & Yokoi, Y. (2003) Critical enhancer region to which
AhR/ARNT and Sp1 bind in the human CYP1B1 gene. J. Biochem. 133:583-592. ...
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The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of … - Full text - MIT Libraries
M Wormke, M Stoner, B Saville, K Walker, M … - Mol Cell Biol, 2003 - mcb.asm.org
... (C) The same membrane reprobed with Sp1 antibody (PEP2 ... TCDD alone (DMSO) and in
combination with proteasome inhibitors (MG132 and PSI) on ER , AhR, Arnt, and ß ...
Cited by 32 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

BOR Papers in Press. Published on February 11, 2004 as DOI: 10.1095/biolreprod. 103.025387
I Genes - biolreprod.org
... 9 an in vitro transcription study using CYP1A1 promoter showed synergistic
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Toxicite de la dioxine: role des proteines" PAS
P Lesca, T Pineau - Med Sci, 1999 - ist.inserm.fr
... complexe, sui- vant la reconnaissance spécifique d’un motif XRE, exerce une transac-
tivation génique durant laquelle AHR coopère avec Sp1 et Arnt avec CBP ...
Cited by 2 - View as HTML - Web Search

… translocation of hypoxia-inducible factor-1 (HIF-1): heterodimerization with ARNT is not necessary … - Full text - MIT Libraries
D Chilov, G Camenisch, I Kvietikova, U Ziegler, M … - J. Cell Sci, 1999 - jcs.biologists.org
... ARNT polyclonal IgG antibodies and the mouse anti-ARNT monoclonal antibody ...
Rabbit-anti Sp1 polyclonal IgG antibodies were purchased from SantaCruz Biotechnology ...
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Inhibition of BRCA-1 expression by benzo [a] pyrene and its diol epoxide - Full text - MIT Libraries
BD Jeffy, EU Schultz, O Selmin, JM Gudas, GT … - Molecular Carcinogenesis, 1999 - doi.wiley.com
... the AhR, and a nuclear translocator protein (AhR nuclear translocator (ARNT)) [27 ...
the p53 [24] and Ha-ras [29] genes and to disrupt Sp1- dependent transcription ...
Cited by 11 - Web Search - breast-cancer-research.com - breast-cancer-research.com - ncbi.nlm.nih.gov - all 8 versions »

Molecular interactions of the aryl hydrocarbon receptor and its biological and toxicological … - Full text - MIT Libraries
P Pocar, B Fischer, T Klonisch, S Hombach-Klonisch - Reproduction, 2005 - reproduction-online.org
... Kobayashi A, Sogawa K & Fujii-Kuriyama Y 1996 Cooperative interaction between
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Dioxin-responsive AHRE-II gene battery: identification by phylogenetic footprinting - Full text - MIT Libraries
PC Boutros, ID Moffat, MA Franc, N Tijet, J … - Biochem Biophys Res Commun, 2004 - okeylabimac.med.utoronto.ca
... between the AHR complex and the ubiqui- tous Sp1 regulatory protein ... First, the AHRÕs
heterodimerization partner protein, ARNT, was shown to directly interact ...
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The aryl hydrocarbon receptor-mediated disruption of vitellogenin synthesis in the fish liver: Cross … - Full text - MIT Libraries
V Bemanian, R Male, A Goksoeyr - Comparative Hepatology, 2004 - dx.doi.org
... been described [34]; in addition, it has been shown that both AHR/ARNT complex
[35] and ERα are able to interact with general transcription factor Sp1 [36,37 ...
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Topic 1.13 Transcriptional roles of AhR in expression of biological effects induced by endocrine …
Y Fujii-Kuriyama, J Mimura - iupac.org
... At the initiation step of transcription, the AhR/Arnt heterodimer and Sp1
synergistically bind their respective cognate DNA sequences by interacting with ...
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Putative link between transcriptional regulation of IgM expression by 2, 3, 7, 8-tetrachlorodibenzo- … - Full text - MIT Libraries
CE Sulentic, MP Holsapple, NE Kaminski - J. Pharmacol. Exp. Ther, 2000 - jpet.aspetjournals.org
... have demonstrated novel protein-protein associations involving the AhR and several
proteins, other than ARNT, including NF- B, Sp1, transcription factor IIB ...
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Occupational exposure to polycyclic aromatic hydrocarbons suppresses constitutive expression of CYP1 …
F Lemm, M Wilhelm, PH Roos - Int. J. Hyg. Environ. Health, 2004 - ingentaconnect.com
... Kobayashi, A., Sogawa, K., Fujii-Kuriyama, Y.: Coop- erative interaction between
AhR.Arnt and Sp1 for the drug-inducible expression of CYP1A1 gene. J. Biol. ...
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Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences - Full text - MIT Libraries
YV Sun, DR Boverhof, LD Burgoon, MR Fielden, TR … - Nucleic Acids Research, 2004 - nar.oupjournals.org
... components. Once in the nucleus, the AhR heterodimerizes with its
bHLH–PAS binding partner, the AhR nuclear translocator (ARNT). ...
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Aryl Hydrocarbon Receptor Gene Silencing with Small Inhibitory RNA Differentially Modulates Ah- … - Full text - MIT Libraries
M Pharmacol - Mol Pharmacol, 2003 - molpharm.aspetjournals.org
... HepG2 cells were transfected with iAhR, iLMN, or iARNT, and AhR, ARNT, or Sp1 proteins
were determined in the various treatment groups by Western blot analysis ...
Cited by 10 - Web Search - dx.doi.org - molpharm.aspetjournals.org - ncbi.nlm.nih.gov

Functional Analysis of Promoter Region from Eel Cytochrome P450 1A1 Gene in Transgenic Medaka - Full text - MIT Libraries
Y Ogino, T Itakura, H Kato, J Aoki, M Sato - Mar. Biotechnol, 1999 - springerlink.com
... Coop- erative interaction between AhR Arnt and Sp1 for the drug- inducible
expression of CYP1A1 gene. J Biol Chem 271:12310– 12316. ...
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Blockage of multidrug resistance-associated proteins potentiates the inhibitory effects of arsenic … - Full text - MIT Libraries
L Vernhet, N Allain, M Le Vee, F Morel, A … - J Pharmacol Exp Ther, 2003 - jpet.aspetjournals.org
... between AhR. Arnt and Sp1 for the drug-inducible expression of CYP1A1 gene.
J Biol Chem 271: 12310-12316 [Abstract/Free Full Text] . ...
Cited by 7 - Web Search - jpet.aspetjournals.org - ncbi.nlm.nih.gov

Induction of VEGF gene expression by retinoic acid through Sp1-binding sites in retinoblastoma Y79 … - Full text - MIT Libraries
H Akiyama, T Tanaka, T Maeno, H Kanai, Y Kimura, S … - Invest Ophthalmol Vis Sci, 2002 - iovs.org
... hypoxia-inducible factor-1 /aryl hydrocarbon receptor translocator (HIF-1 /ARNT)
heterodimer and ... in response to IL-1ß and TNF- is mediated by Sp1-binding sites ...
Cited by 5 - Web Search - iovs.org - ncbi.nlm.nih.gov

Localization of Xenobiotic-responsive Element Binding Protein in Rat Hepatocyte Nuclei After … - Full text - MIT Libraries
Y Asaka, J Watanabe, S Kanamura - J Histochem Cytochem, 1998 - jhc.org
... Kobayashi A, Sogawa K, Fujii–Kuriyama Y (1996) Cooperative interaction between AhR ·
Arnt and Sp1 for the drug-inducible expression of CYP1A1 gene. ...
Cited by 3 - Web Search - jhc.org - ncbi.nlm.nih.gov

Comparative Hepatology - Full text - MIT Libraries
V Bemanian, R Male, A Goksoeyr - Comparative Hepatology, 2004 - bmc.ub.uni-potsdam.de
... has been described [34]; in addition, it has been shown that both AHR/ARNT complex
[35] and ERα are able to interact with general transcription factor Sp1 [36 ...
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Cyclin dependent kinase inhibitor p 27 Kip 1 is upregulated by hypoxia via an ARNT dependent pathway - Full text - MIT Libraries
G Wang, R Reisdorph, RE Clark, R Miskimins, R … - Journal of Cellular Biochemistry, 2003 - doi.wiley.com
... Kip1 Is Upregulated by Hypoxia Via an ARNT Dependent Pathway ... Hepa-1 produces
functional aryl hydrocarbon receptor nuclear translocator (ARNT). ...
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Symposium: _Other (free) topic_
GG Tolna, A Stephenson, P Rehling, P Kovermann, R … - wissenschaft-online.de
... Gel mobility shift assays with various DNA fragments indicated that the GC-Box,
SP1, Ahr/Arnt binding sites interact specifically with nuclear protein (s) of ...
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ERalpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin … - Full text - MIT Libraries
TV Beischlag, GH Perdew - Journal of Biological Chemistry, 2005 - jbc.org
... 1, 2) we were able to demonstrate an interaction between ER and AHR or ARNT. ... GST
fusion chimeras of Sp1 and VP16 failed to precipitate in vitro translated ER . ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Transcriptional suppression of type 1 angiotensin II receptor gene expression by peroxisome … - Full text - MIT Libraries
A Sugawara, K Takeuchi, A Uruno, Y Ikeda, S Arima, … - Endocrinology, 2001 - endo.endojournals.org
... 344[Abstract]; Kobayashi A, Sogawa K, Fujii-Kuriyama Y 1996 Cooperative interaction
between AhR.Arnt and Sp1 for the drug-inducible expression of CYP1A1 gene. ...
Cited by 23 - Web Search - endo.endojournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cellular and molecular biology of aryl hydrocarbon (Ah) receptor-mediated gene expression
S Safe, V Krishnan - Arch Toxicol Suppl, 1995 - ncbi.nlm.nih.gov
... the nucleus as an Ah-receptor:aryl hydrocarbon nuclear translocator (Arnt) protein
heterodimeric ... and this is associated with formation of an ER/Sp1 complex at ...
Cited by 35 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Chapter 2.8 Modulation of Soluble Receptor Signaling by Coregulators
M KUMAR, GH PERDEW - cas.psu.edu
... (ARNT)/single-minded (PAS) domain 43 (Figure 2.8.1), which are found in the AhR,
ARNT, and ... 43 . In the case of the AhR and ARNT, the bHLH and ...
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Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast …
S Safe, M Wormke, I Samudio - J. Mammary Gland Biol. Neoplasia, 2000 - kluweronline.com
... response was further investigated in gel mobililty shift and DNA footprinting assays,
and the results indicate that the AhR/Arnt and ER /Sp1 compete for ...
Cited by 17 - Web Search - springerlink.com - microvet.arizona.edu - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Human CYP1B1 is regulated by estradiol via estrogen receptor - Full text - MIT Libraries
Y Tsuchiya, M Nakajima, S Kyo, T Kanaya, M Inoue, … - Cancer Res, 2004 - cancerres.aacrjournals.org
... Tsuchiya Y, Nakajima M, Yokoi T Critical enhancer region to which AhR/ARNT and Sp1
bind in the human CYP1B1 gene. J Biochem (Tokyo), 133: 583-92, 2003. ...
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GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene … - Full text - MIT Libraries
JL Sepulveda, N Belaguli, V Nigam, CY Chen, M … - Mol. Cell. Biol, 1998 - mcb.asm.org
... In addition, mammalian Nkx-2.1 cooperates with Sp1 and Sp3 to synergistically
activate the Clara cell secretory protein promoter (58). ...
Cited by 130 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Epigenetic regulation of 11ss-hydroxysteroid dehydrogenase type 2 expression - Full text - MIT Libraries
R Alikhani-Koopaei, F Fouladkou, FJ Frey, BM Frey - J. Clin. Invest, 2004 - jci.org
... this window] [in a new window], Figure 4 Binding of nuclear proteins on methylated
or unmethylated putative Arnt- or Sp1/Sp3-binding sites in the HSD11B2 gene. ...
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Functional analysis of the human cytochrome P4501A1 (CYP1A1) gene enhancer
S Kress, J Reichert, M Schwarz - Eur. J. Biochem, 1998 - uni-tuebingen.de
... Upon binding of a ligand, the receptor is released from Hsp90, and heterodimerizes
with a second bHLH protein named Ah-receptor nuclear translocator or ARNT [10 ...
Cited by 8 - View as HTML - Web Search - content.febsjournal.org - ejbiochem.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulation of the Cyp2a5 Gene Involves an Aryl Hydrocarbon Receptor-Dependent Pathway - Full text - MIT Libraries
S Arpiainen, F Raffalli-Mathieu, MA Lang, O … - Mol Pharmacol, 2005 - molpharm.aspetjournals.org
... 1997 ). Furthermore, the hamster CYP2A8 is up-regulated by a mechanism involving
at least AHR, ARNT, and Sp1 (Kurose et al., 1999 ). ...
Web Search - molpharm.org - molpharm.aspetjournals.org - ncbi.nlm.nih.gov - all 5 versions »