[CITATION] Disruption of C/EBP {alpha} Function in Acute Myeloid Leukemia
S Froehling, H Doehner
... Mutational inactivation of PU1, GATA1, and C/EBP has been observed in patients ...
possibility that mutations in the gene encoding C/EBP (CEBPA) could contribute ...
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A leukemogenic twist for GATA 1 - Full text - MIT Libraries
AT Look - Nature Genetics, 2002 - nature.com
... The GATA1 mutations described by Wechsler et al. 4 in AMKL are reminiscent of those
previously identified in acute myeloid leukemias involving CEBPA, which ...
Cited by 2 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

GATA 1- A Player in Normal and Leukemic Megakaryopoiesis - Full text - MIT Libraries
JK HITZLER - Pediatric Research, 2002 - pedresearch.org
... Karp J, Le Beau MM, Crispino JD 2002 Acquired mutations in GATA1 in the ... Behre G,
Hiddemann W, Tenen DG 2001 Dominant-negative mutations of CEBPA, encoding CCAAT ...
Cited by 1 - Web Search - pedresearch.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcription factor expression in cell lines derived from natural killer-cell and natural killer- …
Y Matsuo, HG Drexler, A Harashima, A Okochi, N … - Hum Cell, 2004 - ncbi.nlm.nih.gov
... The present study analyzed the expression of the following 13 TFs: AML1, CEBPA,
E2A, ETS1, GATA1, GATA2, GATA3, IKAROS, IRF1, PAX5, PU1, TBET and TCF1 in 7 ...
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[CITATION] Disruption of C/EBPa Function in Acute Myeloid Leukemia
S Froehling, H Doehner
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Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... CEBP CHOP 559.1 CREB PAX3 125.3 GATA1 PBX1 46.3 AP2 MYCMAX 24.8 ATF WHN
546.3 CEBPA HLF 124.0 MZF1 NFKAPPAB 46.0 CREL MZF1 24.7 ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

[CITATION] Gene-expression profiling in acute myeloid leukemia - Full text - MIT Libraries
D Grimwade, T Haferlach - N Engl J Med, 2004
... and mutations in genes encoding transcription factors involved in normal hematopoiesis,
such as AML1, GATA1, and CCAAT/enhancer binding protein alpha (CEBPA). ...
Cited by 8 - Web Search - lgtc.nl - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT … - Full text - MIT Libraries
DE Zhang, P Zhang, ND Wang, CJ Hetherington, GJ … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
... of the major GATA1 enhancer HS 1 does not affect eosinophil GATA1 expression and ...
Benner, S. Kreitmeier, K. Tobis, H. Dohner, and K. Dohner CEBPA Mutations in ...
Cited by 353 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

A panorama of lineage-specific transcription in hematopoiesis - Full text - MIT Libraries
Y Kluger, Z Lian, X Zhang, PE Newburger, SM … - BioEssays, 2004 - doi.wiley.com
... Here we show exemplar transcription factors, GATA1, PU.1 FOG1, C-JUN, CUTL1, CEBPA,
CEBPB and CEBPE, with important roles in hematopoietic lineages ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Development of a human acute myeloid leukaemia screening panel and consequent identification of …
ML Smith, R Arch, LL Smith, N Bainton, M Neat, C … - ingentaconnect.com
... H., Haas, OA & Izraeli, S. (2003) Mutations in exon 2 of GATA1 are early ... JA, Rohatiner,
AZ, Lister, TA & Fitzgibbon, J. (2003) Mutations of CEBPA in acute ...
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Research Paper Development of a human acute myeloid leukaemia screening panel and consequent … - Full text - MIT Libraries
ML Smith, R Arch, LL Smith, N Bainton, M Neat, C … - British Journal of Haematology, 2005 - blackwell-synergy.com
... Analysis was performed on six genes known to be mutated in AML (RUNX1, FLT3, KIT,
CEBPA, PTPN11 and NRAS) and an additional two candidate genes (CCND3 and FES ...
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Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU. 1 - Full text - MIT Libraries
F Rosenbauer, K Wagner, JL Kutok, H Iwasaki, MM Le … - Nature Genetics, 2004 - nature.com
... Dominant negative mutations of CEBPA, encoding CCAAT/Enhancer Binding Protein-
(C ... Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down Syndrome. ...
Cited by 13 - Web Search - nature.com - ncbi.nlm.nih.gov - origin.www.nature.com

Halte a la plasticite
JC Ameisen, R Ardaillou, R Barouki, P Borensztein, … - erudit.org
... le chromosome 21, la protéine anormale délétée Δnt-GATA1 se comporte ... aiguës
myéloblastiques, un phénomène analogue avec le gène CEBPA (CCAAT enhancer ...
Cached - Web Search

Effect of transcription-factor concentrations on leukemic stem cells - Full text - MIT Libraries
F Rosenbauer, S Koschmieder, U Steidl, DG Tenen - Blood, 2005 - bloodjournal.org
... Interplay of pu.1 and gata1 determines myelo-erythroid progenitor cell fate ...
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... Table 2 TFBS with known “terminal N” artifacts in TRANSFAC ® TFBS family Description
GATA1 02 GATA-binding factor 1 GATA1 03 GATA-binding factor 1 GATA1 ...
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Disruption of differentiation in human cancer: AML shows the way - Full text - MIT Libraries
DG Tenen - Nature Reviews Cancer, 2003 - nature.com
1. Nichols, J. & Nimer, SD Transcription factors, translocations, and leukemia.
Blood 80, 2953-2963 (1992). | PubMed | ISI | ChemPort |. 2. ...
Cited by 66 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Progress in Hematology
S Koschmieder, F Rosenbauer, U Steidl, BM Owens, … - Int J Hematol, 2005 - cardenjennings.metapress.com
... hypomorphic mice CEBPA [16,25,86] Hematopoietic cells (HSCs, CMPs, Lack of
granulocytes, Same as for knock-out plus M-CSFR, GM-CSFR, GMPs ...
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Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and … - Full text - MIT Libraries
K Shakib, JT Norman, LG Fine, LR Brown, J Godovac- … - Proteomics, 2005 - doi.wiley.com
... 2. Other Transcription Factors Gata1 GATA binding protein 1 (GATA1D, GATA1) 6978877
6978877 . ... pro- tein zeta [GI:42542392] and to mouse CBF1 or CEBPA-RS1: CCAAT ...
Web Search - ncbi.nlm.nih.gov

Loss of C/EBP {alpha} cell cycle control increases myeloid progenitor proliferation and transforms … - Full text - MIT Libraries
BT Porse, D Bryder, K Theilgaard-Moench, MS … - J Exp Med, 2005 - jem.org
... 2003. Mutations of CEBPA in acute myeloid leukemia FAB types M1 and M2. ... 2002. Acquired
mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. ...
Cited by 1 - Web Search - jem.org

Translational control of SCL-isoform expression in hematopoietic lineage choice - Full text - MIT Libraries
CF Calkhoven, C Mueller, R Martin, G Krosl, T … - Genes & Development, 2003 - genesdev.org
... Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-
(C ... Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. ...
Cited by 6 - Web Search - genesdev.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Clonogenicity, gene expression and phenotype during neutrophil versus erythroid differentiation of … - Full text - MIT Libraries
L Edvardsson, J Dykes, ML Olsson, T Olofsson - British Journal of Haematology, 2004 - ask.lub.lu.se
... ABO transferase Hs 00220850_m1 CEBPA C/EBPa Hs 00269972_s1 CEBPE C/EBPe Hs 00357657_m1
AHSP/ERAF AHSP/EDRF Hs 00372339_g1 EPOR EpoR Hs 00181092_m1 GATA1 GATA-1 ...
Cited by 1 - View as HTML - Web Search - ncbi.nlm.nih.gov

Proteomic analysis of transcription factor interactions in myeloid stem cell development and …
G Behre, VA Reddy, DG Tenen, W Hiddemann, AA Peer … - Expert Opinion on Therapeutic Targets, 2002 - dx.doi.org
... Ery GATA1 ... 8. PABST T, MUELLER BU, ZHANG P et al.: Dominant negative mutations of
CEBPA, encoding CCAAT/ enhancer binding protein-alpha (C/ EBPalpha), in acute ...
Cited by 4 - Web Search - ingentaconnect.com - ashley-pub.com - definiens.com - all 8 versions »

Novel transcription factors in human CD34 antigen-positive hematopoietic cells - Full text - MIT Libraries
I Gomes, TT Sharma, S Edassery, N Fulton, BG Mar, … - Blood, 2002 - bloodjournal.org
... 6 whereas GATA1 and GATA2 are down-regulated. ... Hs.765 GATA1 GATA-binding
protein 1 (globin transcription factor 1) Xp11.23 9.0 L W ...
Cited by 3 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Genetic and genomic approaches to study placental development - Full text - MIT Libraries
M Hemberger, U Zechner, F Alert - Cytogenetic and Genome Research, 2004 - content.karger.com
Page 1. Genome in Development and Cloning Cytogenet Genome Res 105:257–269 (2004)
DOI: 10.1159/000078197 Genetic and genomic approaches to study ...
Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

Predicting the effect of transcription therapy in hematologic malignancies
A Melnick - Leukemia, 2005 - nature.com
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Please read our explanation of accessible NPG websites. ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

CCAAT/ENHANCER-BINDING PROTEINS IN MYELOID CELLS
DER ZHANG - doi.wiley.com
... C/EBP can synergize with NF B to activate IL-8 and IL-12 (Oettgen et al., 1996;
Plevy et al., 1997; Stein and Baldwin, 1993), synergyze with GATA1 to activate ...
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Gene expression profiling of pediatric acute myelogenous leukemia - Full text - MIT Libraries
ME Ross, R Mahfouz, M Onciu, HC Liu, X Zhou, G … - Blood, 2004 - bloodjournal.org
... the megakaryocyte lineage. 62-64 These include glycoproteins IIb/IIIa (GP1BB
and ITGA2B), GATA1, and MRPS12. In addition, we identified ...
Cited by 8 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov

Ras signaling enhances the activity of C/EBPα to induce granulocytic differentiation by …
SM Singh, I Gonda - edoc.ub.uni-muenchen.de
... Heterozygous mutations were found in CEBPA gene in ten patients ... differentiation.
It is the first report of CEBPA gene mutations in ...
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The granulocytic inducer C/EBP a inactivates the myeloid master regulator PU. 1: possible role in …
AMK und Poliklinik, III am Klinikum Grosshadern - edoc.ub.uni-muenchen.de
... regulators. The various factors known, so far, to interact are PU.1 interacting
protein (Pip), NF-IL6 (C/EBPd), c-Jun, TBP, RB, GATA1 and CBP 115-117 , 107 . ...
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Dokumentation und Evaluation der Weiterbildung Abstracts
S mit Nabelschnurblut, E Session, SC … - Onkologie, 2004 - content.karger.com
Page 1. 8 Stammzelltransplantation mit Nabelschnurblut Ch. Urban Klinische Abteilung
für Pädiatrische Hämatologie/Onkologie Universitätsklinik ...
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Bibliography Current World Literature
J Arcaroli, KY Yang, HK Yum… - Current Opinion in Hematology, 2004 - co-hematology.com
January 2004, 11:1 > Bibliography Current World Literature. < Previous | Next >. ...
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