MOLECULAR TARGETS FOR THERAPY (MTT)
J Roche, C Zeng, A Baron, S Gadgil, RM Gemmill, I … - Leukemia, 2004 - nature.com
... of human leukemia, including translocations that fuse NUP98 with HOXA9, A11, A13 ...
was associated with more FLT3 mutations and, conversely, fewer CEBPa mutations. ...
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Human AML1/MDS1/EVI1 fusion protein induces an acute myelogenous leukemia (AML) in mice: A model for … - Full text - MIT Libraries
GM Cuenco, G Nucifora, R Ren - J. Clin. Invest, 2004 - dx.doi.org
... T. Pabst The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute ... G. Sauvageau
Oncogenic interaction between BCR-ABL and NUP98-HOXA9 demonstrated by ...
Cited by 31 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

G ENETIC P ROFILE OF A CUTE M YELOID L EUKEMIA - Full text - MIT Libraries
C Mecucci, R Rosati, R La Starza - Reviews in Clinical & Experimental Hematology, 2002 - blackwell-synergy.com
... The leukemogenic potential of NUP98/HOXA9 protein was tested in vitro by transformation
of NIH 3T3 fibroblasts, and in vivo in transplanted mice (54). ... CEBPA. ...
Cited by 4 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT … - Full text - MIT Libraries
DE Zhang, P Zhang, ND Wang, CJ Hetherington, GJ … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
... page, J Clin Oncol Home page S. Frohling, RF Schlenk, I. Stolze, J. Bihlmayr, A.
Benner, S. Kreitmeier, K. Tobis, H. Dohner, and K. Dohner CEBPA Mutations in ...
Cited by 353 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Gene Expression Profiling of Adult Acute Myeloid Leukemia Identifies Novel Biologic Clusters for …
CS Wilson, GS Davidson, SB Martin, E Andries, Y Xu … - hsc.unm.edu
... tyrosine kinase (FLT3), Wilms tumor (WT1), EVI1, RAS, and CEBPA in AML have ... An
interesting finding is the decreased expression of homeobox A9 (HoxA9) and A10 ...
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Acute Leukemias New insights into MLL gene rearranged acute leukemias using gene expression …
A Kohlmann, C Schoch, M Dugas, S Schnittger, W … - Leukemia, 2005 - nature.com
... As given in Figure 3, HOXA9 as well as MEIS1 show up as genes with ... with
t(11q23)/MLL could be demonstrated by differential expression of CEBPA (CCAAT/enhancer ...
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G ENETICS OF M YELOID L EUKEMIAS - Full text - MIT Libraries
LM Kelly, DG Gilliland - Annual Review of Genomics and Human Genetics, 2002 - genom.annualreviews.org
... For example, some cases of BCR/ABL-positive CML progress to AML with acquisition
of at[7;11] resulting in expression of a NUP98/HOXA9 fusion gene (3, 100). ...
Cited by 35 - Web Search - 128.194.251.107 - fluid.annualreviews.org - ncbi.nlm.nih.gov - all 5 versions »

Gene expression profiling of pediatric acute myelogenous leukemia - Full text - MIT Libraries
ME Ross, R Mahfouz, M Onciu, HC Liu, X Zhou, G … - Blood, 2004 - bloodjournal.org
... these are genes that are expressed in the majority of MLL chimeric fusion
gene–containing cases, including MBNL1, MEIS1, HOXA4, HOXA5, HOXA9 HOXA10, and MYH9 ...
Cited by 8 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov

EFFECTIVE USE OF WEB-BASED PUBLIC GENOMIC DATABANKS FOR AUTOMATIC AND UPDATED PERSONAL ANNOTATIONS …
M Masseroli, A Stella, GE Carrara, M Mazzarani, M … - bioinformatics.polimi.it
... D G protein-coupled receptor 65 GPR65 X D homeo box A9 HOXA9 X X X D homeo box A10
HOXA10 X X X X X ... I CCAAT/enhancer binding protein (C/EBP), alpha CEBPA X ...
Web Search - medinfopoli.polimi.it - bioinformatics.polimi.it - medinfopoli.polimi.it

Molecular pathogenesis of MDS
H Hirai - Int J Hematol, 2002 - haem.nus.edu.sg
... p15;p15), t(2;11)(q31;p15), t(11;17) (p15;q21), t(11;12)(p15;q13), t(11;20)(p15;
q11), and inv(11) (p15q22) result in generation of NUP98/HOXA9, NUP98/ HOXD13 ...
Cited by 3 - View as HTML - Web Search - ishapd.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Molecular Mechanisms of Myelodysplastic Syndrome - Full text - MIT Libraries
H Hirai - Japanese Journal of Clinical Oncology, 2003 - jjco.oupjournals.org
... Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome ... Dominant-negative
mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha ...
Cited by 5 - Web Search - jjco.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Gene Expression Profiling during All-trans Retinoic Acid-Induced Cell Differentiation of Acute … - Full text - MIT Libraries
L Yang, H Zhao, SW Li, K Ahrens, C Collins, S … - Journal of Molecular Diagnostics, 2003 - jmd.amjpathol.org
... 0.88 0.65 0.24 0.36 0.59 PTD010 PTD010 protein 0.48 1.28 0.68 0.37 0.46 CEBPA
CCAAT/EBP, alpha 1.19 0.62 0.8 0.38 0.29 RAD53 protein kinase Chk2 ...
Cited by 1 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

EL MIELOBLASTO EN EL CONTEXTO DE LA LMA
FOCR de Hemodonacion - db2.doyma.es
Page 1. EL MIELOBLASTO EN EL CONTEXTO DE LA LMA C OORDINADORES : L. E SCRIBANO .
Hospital Ramón y Cajal. Madrid F. O RTUÑO . Centro Regional de Hemodonación. ...
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The effects of Bcr-Abl on C/EBP transcription-factor regulation and neutrophilic differentiation are … - Full text - MIT Libraries
C Schuster, K Forster, H Dierks, A Elsaesser, G … - Blood, 2003 - bloodjournal.org
... 2 Moreover, fusion genes resulting from reciprocal translocations such as
AML/EVI-1 or NUP98/HoxA9 have been reported to be associated with some cases of ...
Cited by 6 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Gene Expression Profiling and Microarrays Gene expression profiling of leukemic cell lines reveals …
A Andersson, P Eden, D Lindgren, J Nilsson, C … - Leukemia, 2005 - nature.com
... Comparing AML and ALL, we identified CEBPA, a myeloid transcription factor of ... Hoxa9
and Meis1 are key targets for MLL-ENL-mediated cellular immortalization. ...
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Pathogenesis of acute myeloid leukaemia and inv (16)(p 13; q 22): a paradigm for understanding … - Full text - MIT Libraries
JT Reilly - British Journal of Haematology, 2005 - blackwell-synergy.com
... mutations, namely PML RARA (Scolnik et al, 1998), AML1 ETO (Ferro et al, 1992; Kojima
et al, 1999), AML1-EVI1 (Cuenco & Ren, 2001) and NUP98 HOXA9 (Yamamoto et ...
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The granulocytic inducer C/EBP a inactivates the myeloid master regulator PU. 1: possible role in …
AMK und Poliklinik, III am Klinikum Grosshadern - edoc.ub.uni-muenchen.de
... positively regulates granulocytic/monocytic differentiation, whereas its
down-regulation is necessary for progression of erythropoiesis HOXA9 important role ...
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Transcription factors, normal myeloid development, and leukemia - Full text - MIT Libraries
DG Tenen, R Hromas, JD Licht, DE Zhang - Blood, 1997 - bloodjournal.org
PDF Version of this Article. Citation Map. Email this article to a friend. Similar
articles found in: Blood Online PubMed. PubMed Citation. ...
Cited by 353 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Novel transcription factors in human CD34 antigen-positive hematopoietic cells - Full text - MIT Libraries
I Gomes, TT Sharma, S Edassery, N Fulton, BG Mar, … - Blood, 2002 - bloodjournal.org
Page 1. HEMATOPOIESIS Novel transcription factors in human CD34 antigen–positive
hematopoietic cells Ignatius Gomes, Tiffany T. Sharma ...
Cited by 3 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Molecular Cytogenetic Aspects of Hematological Malignancies: Clinical Implications
Z CHEN, AA SANDBERG - American Journal of Medical Genetics (Semin. Med. Genet.), 2002 - doi.wiley.com
Page 1. American Journal of Medical Genetics (Semin. Med. Genet.) 115:130–141
(2002) ARTICLE Molecular Cytogenetic Aspects of Hematological ...
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