Sp1 and Egr1 regulate transcription of the Dmrt1 gene in Sertoli cells - Full text - MIT Libraries
N Lei, LL Heckert - Biol Reprod, 2002 - biolreprod.org
... The positive elements bind the transcription factors Sp1, Sp3, and Egr1, suggesting
that these ... have, in part, been described and include the genes for Sry, SF-1 ...
Cited by 11 - Web Search - bioone.org - biolreprod.org - ncbi.nlm.nih.gov - all 5 versions »

The one-to-four rule and paralogues of sex-determining genes - Full text - MIT Libraries
S Ohno - Cell. Mol. Life Sci, 1999 - springerlink.com
... there is a gene which is an antagonist of SRY. As already noted, whereas WT1 functions
as a transcrip- tional repressor in nephroblastic cells, EGR1 acts as a ...
Cited by 16 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Clusterin Gene in Rat Sertoli Cells Is Regulated by a Core-Enhancer Element - Full text - MIT Libraries
ES Lymar, AM Clark, R Reeves, MD Griswold - Biology of Reproduction, 2000 - bioone.org
... include two each of high mobility group protein I(Y) (HMG-I[Y]), Sp1, Ets, and CBF
sites and one each of Pets-like, Sry-related HMG-box protein/Sry, Egr1, and C ...
Web Search - biolreprod.org - biolreprod.org - ncbi.nlm.nih.gov - all 5 versions »

Testosterone activates mitogen-activated protein kinase and the cAMP response element binding … - Full text - MIT Libraries
C Fix, C Jordan, P Cano, WH Walker - Proceedings of the National Academy of Sciences - pnas.org
... 3' and 5'-CATGCGATACTCATTGAAAACCAGGTC-3'; SRY, 5'-ACCTGCTGCAATGGGACAACAACC-3' and
5 ... 3' and 5'-TTAGAACTGCAGCTCCTTCTGGA-3'; EGR1, 5'-TTCGCTCACTCCACTATCCAC-3' and 5 ...
Cited by 5 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Alterations of Sex Differentiation in Males: From Candidate Genes to Diagnosis and Treatments
H Ostrer - Current Pharmaceutical Design, 2004 - ingentaconnect.com
... The WT1 –KTS isoform plays a role in SRY induction through a proximal EGR1-like
DNA-binding sequence in the core promoter of the SRY gene [41]. ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Minireview: genetic models for the study of gonadotropin actions - Full text - MIT Libraries
KH Burns, MM Matzuk - Endocrinology, 2002 - endo.endojournals.org
... sensitive sex reversal-like condition in mice with a hypomorpic Sry (sex determining ...
critical in the establishment of the HPG endocrine axis, EGR1 (also known ...
Cited by 11 - Web Search - endo.endojournals.org - ncbi.nlm.nih.gov

Genetic causes of human reproductive disease - Full text - MIT Libraries
JC Achermann, G Ozisik, JJ Meeks, JL Jameson - J Clin Endocrinol Metab, 2002 - dx.doi.org
... in gonadotrope-specific genes have been described yet (eg Egr1) (Fig. ... whereas
overexpression or inappropriate expression of the testis genes, SRY and SOX9 ...
Cited by 17 - Web Search - jcem.endojournals.org - ncbi.nlm.nih.gov

GENE INTERACTIONS IN GONADAL DEVELOPMENT - Full text - MIT Libraries
KL Parker, A Schedl, BP Schimmer - Annual Review of Physiology, 1999 - physiol.annualreviews.org
... is identifying the genes that act upstream and downstream of SRY in sex ... the last
three of which show high homology with the transcription factors Sp1 and Egr1. ...
Cited by 51 - Web Search - physiol.annualreviews.org - d.umn.edu - ncbi.nlm.nih.gov

Transcription factors as targets for DNA-interacting drugs
M Gniazdowski, WA Denny, SM Nelson, M Czyz - Curr. Med. Chem, 2003 - ingentaconnect.com
Page 1. Current Medicinal Chemistry, 2003, 10, 909-924 909 0929-8673/03
$41.00+.00 © 2003 Bentham Science Publishers Ltd. Transcription ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Transcriptional control in myelinating glia: The basic recipe - Full text - MIT Libraries
M Wegner - Glia, 2000 - doi.wiley.com
... so far in cells of the oligoden- drocyte lineage is Krox-24/Egr1 that is ... of all Sox
proteins is similar to the one in the male sex-determining factor SRY. ...
Cited by 19 - Web Search - doi.wiley.com - biochem.uni-erlangen.de - ncbi.nlm.nih.gov

State-of-the-Art Review
E ALGAR - JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH, 2002 - dx.doi.org
... at its carboxylterminus, resembling those in the zinc-finger transcription factor,
EGR1 (3). The ... XY sex re- versal due to a reduction in Sry expression levels. ...
Web Search - liebertonline.com - liebertonline.com

Gata4 regulates testis expression of Dmrt1 - Full text - MIT Libraries
N Lei, LL Heckert - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... and the positive elements bind the transcription factors Sp1, Sp3, and Egr1 (Fig ...
Chromosomal sex was determined by PCR using Sry-specific primers (data not shown ...
Cited by 3 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Expression of DMRT 1 in the mammalian ovary and testis – from marsupials to mice - Full text - MIT Libraries
AJ Pask, RR Behringer, MB Renfree, F Alert - Cytogenetic and Genome Research, 2003 - content.karger.com
... JAM, Renfree MB: Widespread expression of the testis determining gene SRY in a ... External
Resources Lei N, Heckert LL: Sp1 and Egr1 regulate transcription of the ...
Cited by 2 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

Genomic approaches to identifying transcriptional regulators of osteoblast differentiation - Full text - MIT Libraries
J Stains, R Civitelli - Genome Biology, 2003 - pubmedcentral.nih.gov
... In contrast, ZNF6 and EGR1 were markedly down-regulated. ... Sox genes, encoding
homeobox-containing transcription factors related to the SRY sex-determining gene ...
Web Search - genomebiology.com - citebase.eprints.org - dx.doi.org - all 7 versions »

Thrombin Modulates the Expression of a Set of Genes Including Thrombospondin-1 in Human … - Full text - MIT Libraries
S Data - J. Biol. Chem, 2005 - jbc.org
... 3'; EGR1 sense, 5'-AGG ACA GGA GGA GGA GAT GG-3', and EGR1 antisense, 5 ... Transcription
factors such as SRY (sex determining region Y)-box 15 (SOX15), zinc finger ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Genetic dissection of mammalian fertility pathways - Full text - MIT Libraries
MM Matzuk, DJ Lamb - Nature Cell Biology, 2002 - mrg.genetics.washington.edu
... and infertility revealed that many XX males have translocations of a small piece
of the Y chromosome,so that the sex-determining region Y gene (SRY) results in ...
Cited by 60 - View as HTML - Web Search - nature.com - tu-cottbus.de - ncbi.nlm.nih.gov - all 5 versions »

Conservation of the function of DMRT1 regulatory sequences in mammalian sex differentiation. - Full text - MIT Libraries
A Boyer, S Dornan, I Daneau, J Lussier, DW … - Genesis, 2002 - doi.wiley.com
... The porcine SRY promoter is transancti- vated within a male genital ridge environment. ...
Sp1 and Egr1 regulate transcription of the Dmrt1 gene in Sertoli cells. ...
Web Search - ncbi.nlm.nih.gov

Wnt-4 regulation by the Wilms' tumour suppressor gene, WT 1 - Full text - MIT Libraries
EUH Sim, A Smith, E Szilagi, F Rae, P Ioannou, MH … - Oncogene, 2002 - nature.com
... target genes described in the literature include other transcription factors (Pax2,
EGR1, c-myc, c ... Of note was the presence of a potential Sry-binding site (5 ...
Cited by 11 - Web Search - nature.com - ncbi.nlm.nih.gov

A novel mutation in DAX1 causes delayed-onset adrenal insufficiency and incomplete hypogonadotropic … - Full text - MIT Libraries
A Tabarin, JC Achermann, D Recan, V Bex, X … - J Clin Invest, 2000 - jci.org
... Cotransfection of human SF1 (FTZF1) (20 ng) with rat Egr1 (20 ng) produced ... to antagonize
the actions of the testis-determination factor, SRY, in gonadal ...
Cited by 45 - Web Search - pubmedcentral.nih.gov - jamesonlab.northwestern.edu - endocrine.northwestern.edu - all 6 versions »

Schwann cells and their precursors emerge as major regulators of nerve development
KR Jessen, R Mirsky - J. Neurosci. Res - homepages.ucl.ac.uk
... in this system include the zinc-finger protein EGR1 (also known as Krox-24) and
SOX10, a member of the SRY- like high mobility group (HMG) domain class of tran ...
Cited by 93 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Human Genome Screen to Identify the Genetic Basis of the Anti-inflammatory Effects of Boswellia in …
S Roy, S Khanna, H Shah, C Rink, C Phillips, H … - DNA and Cell Biology, 2005 - dx.doi.org
Page 1. 244 DNA AND CELL BIOLOGY Volume 24, Number 4, 2005 © Mary Ann Liebert, Inc.
Pp. 244–255 Human Genome Screen to Identify the Genetic Basis of the ...
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Mice Deficient in the Orphan Receptor Steroidogenicfd Factor 1 Lack Adrenal Glands and Gonads but … - Full text - MIT Libraries
Y Sadovsky, PA Crawford, KG Woodson, JA Polish, MA … - Proceedings of the National Academy of Sciences - pnas.org
... and SH Orkin Gonadal differentiation, sex determination and normal Sry expression
in ... Reprod Home page N. Lei and LL Heckert Sp1 and Egr1 Regulate Transcription ...
Web Search

36th American Cytogenetics Conference
TX Galveston - Cytogenet Cell Genet, 2000 - content.karger.com
Page 1. Cytogenet Cell Genet 90:154–168 (2000) The First American Cytogenetics
Conference Distinguished Cytogeneticist Award presented to Dr. TC Hsu ...
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Expression of Steroidogenic Factor 1 in the Testis Requires an Interactive Array of Elements Within … - Full text - MIT Libraries
SP Scherrer, DA Rice, LL Heckert - Biology of Reproduction, 2002 - bioone.org
... gonad formation and sex determination are thought to be regulated by Sry, Sox9,
and ... Antibodies against USF1, USF2, Wt1, Egr1, Sp1, Sp2, Sp3, Sp4, Coup TFII, E47 ...
Cited by 4 - Web Search - biolreprod.org - biolreprod.org - ncbi.nlm.nih.gov - all 5 versions »

Regulation of gene expression by WT1 in development and tumorigenesis
LW Ellisen - Int. J. Hematol, 2002 - cardenjennings.metapress.com
... WT1 with 20- to 30-fold greater affinity than the EGR1 sequence, and ... do demonstrate
markedly decreased expression of the sex-determining factor SRY, which has ...
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A spectrum of functional genes mobilized after Trichinella spiralis infection in skeletal muscle
Z WU, I NAGANO, T BOONMARS, Y TAKAHASHI - Parasitology, 2005 - journals.cambridge.org
... x 9+ M20157 early growth response 1 (EGR1) x 6+ X14759 homeobox, msh-like 1 x 6+
L12705 engrailed 2 ... 6+ 6+ 1 . 1 D49474 SRY-box containing gene 17 4+ 4+ 1 . 1 ...
Cited by 1 - Web Search - journals.cambridge.org - journals.cambridge.org

Full Text View - Full text - MIT Libraries
SP Scherrer, DA Rice, LL Heckert - Biology of Reproduction - bioone.org
... gonad formation and sex determination are thought to be regulated by Sry, Sox9,
and ... Antibodies against USF1, USF2, Wt1, Egr1, Sp1, Sp2, Sp3, Sp4, Coup TFII, E47 ...
Web Search

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... PAX4 04 Pax-4 binding sites PAX6 01 Pax-6 PU1 B Pu.1 (Pu120) Ets-like transcription
factor identified in lymphoid B-cells S8 01 S8 SOX9 B1 SOX (SRY-related HMG ...
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Array-based comparative genomic hybridization for the detection of DNA sequence copy number changes … - Full text - MIT Libraries
B Albrecht, M Hausmann, H Zitzelsberger, H Stein, … - The Journal of Pathology, 2004 - doi.wiley.com
... PDZ-GEF1 40TEL11 D4S2930 C84C11/T3 D5S23 D5S2064 DAB2 DHFR,MSH3 APC EGR1 CSF1R NIB1408 ...
exon 45-51 DXS580 DXS7132 AR 3' XIST OCRL1 EST CDY16c07 SRY AZFa region ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Large scale molecular analysis identifies genes with altered expression in salivary adenoid cystic … - Full text - MIT Libraries
HF Frierson, AK El-Naggar, JB Welsh, LM Sapinoso, … - Am J Pathol, 2002 - ajp.amjpathol.org
... 33131_at SOX4 SRY (sex determining region Y)-box 4 NM_003107 Hs.83484 6.92E ... 38692_at
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) NM_005966 Hs.107474 ...
Cited by 13 - Web Search - ajp.amjpathol.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

The role of WT1 in oncogenesis: tumor suppressor or oncogene
DM Loeb, S Sukumar - Int. J. Hematol, 2002 - cardenjennings.metapress.com
... Among these are the genes for müllerian inhibiting sub- stance (MIS) [91], SRY
[92], Nov [93], the androgen recep- tor [92], and Dax-1 [94]. ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray - Full text - MIT Libraries
A Saito-Hisaminato, T Katagiri, S Kakiuchi, T … - DNA Res, 2002 - dna-res.kazusa.or.jp
Page 1. DNA Research 9, 35–45 (2002) Genome-Wide Profiling of Gene Expression
in 29 Normal Human Tissues with a cDNA Microarray ...
Cited by 16 - View as HTML - Web Search - ncbi.nlm.nih.gov

Expression of Dmrt 1 in a turtle with temperature-dependent sex determination - Full text - MIT Libraries
C Murdock, T Wibbels, F Alert - Cytogenetic and Genome Research, 2003 - content.karger.com
... Homologues for SRY (the master switch for sex determination for many mammalian ... Three
zinc finger transcription factors, Sp1, Egr1, and Sp3 were identified and ...
Cited by 2 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 6 versions »

Hematopoietic stem cells do not repair the infarcted mouse heart
A Deten, HC Volz, S Clamors, S Leiblein, W Briest, … - Cardiovasc Res, 2005 - webmed.zmai.uni-leipzig.de
... Cardiovascular Research 65 (2005) 52–63 57 Page 7. some (SRY, GenBank Accession
No. ... (C) DNA (2 Ag) and SRY primers only from the infarct area of MI-lin ...
Cited by 3 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Meningioma Expression Analysis
G Wrobel - dkfz-heidelberg.de
Page 1. Meningioma Expression Analysis Gunnar Wrobel February 26, 2004 Page
2. Contents 1 Preprocessing 3 1.1 Introduction . . . . . ...
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Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that … - Full text - MIT Libraries
T Niimi, NG Copeland, DJ Gilbert, NA Jenkins, A … - Cytogenetic and Genome Research, 2002 - content.karger.com
... 5, IL13: interleukin 13, IL4: interleukin 4, IL9: interleukin 9, EGR1: early growth ...
M, Tezuka T, Yoshida M, Semba K: Identification of a novel Sry-related gene ...
Cited by 3 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 6 versions »

Technical Advance
SJ Scheidl, S Nilsson, M Kalen, M Hellstroem, M … - American Journal of Pathology, 2002 - ajp.amjpathol.org
Page 1. Technical Advance mRNA Expression Profiling of Laser Microbeam
Microdissected Cells from Slender Embryonic Structures Stefan ...
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Structural and functional characterization of the mouse Hlx homeobox gene - Full text - MIT Libraries
MD Bates, LC Schatzman, T Lints, PE Hamlin, RP … - Mammalian Genome, 2000 - springerlink.com
... 71–79 Denny P, Swift S, Connor F, Ashworth A (1992) An SRY-related gene ... of the DNA
binding characteristics of the related zinc finger proteins WT1 and EGR1. ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Impact of genetic engineering on the understanding of spermatogenesis - Full text - MIT Libraries
D Escalier - Human Reproduction Update, 2001 - humupd.oupjournals.org
... Egr4-Egr1 double mutants have permitted the elucidation of the level of redundancy
between these Egr family members in regulating luteinizing hormone ...
Cited by 35 - Web Search - ingentaconnect.com - oup.co.uk - ncbi.nlm.nih.gov - all 6 versions »

The Helix-Loop-Helix Inhibitor of Differentiation (ID) Proteins Induce Post-Mitotic Terminally … - Full text - MIT Libraries
J Chaudhary, I Sadler-Riggleman, JM Ague, MK … - BIOLOGY OF REPRODUCTION, 2005 - biolreprod.org
... Some Sertoli cell genes such as cyclic 15 protein 2 (cathepsin L) and Sry Related
HMG box protein-11 (Sox11) increase in expression. At no ...
Web Search - biolreprod.org - ncbi.nlm.nih.gov

Genomics of the periinfarction cortex after focal cerebral ischemia
A Lu, Y Tang, R Ran, JF Clark, BJ Aronow, FR Sharp - J Cereb Blood Flow Metab, 2003 - nature.com
Page 1. Genomics of the Periinfarction Cortex After Focal Cerebral Ischemia
*Aigang Lu, *Yang Tang, *Ruiqiong Ran, *Joseph F. Clark ...
Cited by 18 - View as HTML - Web Search - nature.com - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Molecular Endocrinology. First published June 10, 2004 as doi: 10.1210/me. 2004-0173
K Morohashi - mend.endojournals.org
... as Sox9 (13), Gata4 (14), Wt1 (15, 16), PITX1 (17), MBF1 (18), EGR1 (19,
20), and TReP-132 (21) ... 1998 Direct interaction of SRY-related ...
Web Search

Identification of Genes Induced in Peripheral Nerve after Injury - Full text - MIT Libraries
E PROFILING, NG DISCOVERY - J. Biol. Chem, 2001 - jbc.org
... Clearly, those encoding transcription factors, like Fos, Jun, and Egr1 are likely
to ... POU-domain proteins like Tst-1/Oct6/SCIP (61), a SRY family protein Sox10 ...
Web Search - jbc.org

Small Ubiquitin-Like Modifier 1 (SUMO-1) Modification of the Synergy Control Motif of Ad4 Binding … - Full text - MIT Libraries
T Komatsu, H Mizusaki, T Mukai, H Ogawa, D Baba, M … - Molecular Endocrinology - mend.endojournals.org
... Wt1 (15, 16), PITX1 (17), multiprotein bridging factor 1 (MBF1) (18), EGR1 (19,
20 ... Scherer G, Poulat F, Berta P 1998 Direct interaction of SRY-related protein ...
Cited by 5 - Web Search - dx.doi.org - mend.endojournals.org - ncbi.nlm.nih.gov

The DEAD-Box Protein DP103 (Ddx20 or Gemin-3) Represses Orphan Nuclear Receptor Activity via SUMO … - Full text - MIT Libraries
MB Lee, LA Lebedeva, M Suzawa, SA Wadekar, M … - Molecular AND Cellular Biology, 2005 - mcb.asm.org
... evidence that they function to silence transcription factors, including nuclear
receptors, Egr1 to 4 ... Dax1 antagonizes Sry action in mammalian sex determination. ...
Web Search - subhagya.wadekar.tripod.com - ucsf.edu - ncbi.nlm.nih.gov - all 6 versions »

JBC Papers in Press. Published on October 24, 2001 as Manuscript M107795200
C Kumar-Sinha, S Varambally, A Sreekumar, AM … - jbc.org
Page 1. Molecular Cross-Talk Between the TRAIL and Interferon Signaling Pathways
Chandan Kumar-Sinha, Sooryanarayana Varambally, Arun ...
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Cross signaling, cell specificity, and physiology - Full text - MIT Libraries
JE Dumont, S Dremier, I Pirson, C Maenhaut - Am J Physiol Cell Physiol, 2002 - intl-ajpcell.physiology.org
... immediate genes. C-Fos and Egr1, which are induced in many cells in response
to all sorts of signals, are an obvious example (372). Cell ...
Cited by 8 - Web Search - ajpcell.physiology.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TranSignal TM Protein/DNA Arrays
CS Version - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays (Column Separation Version) Cat. #
MA1210, MA1211, MA1212l, MA1213 & MA1214, MA1215 Product ...
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