ORIGINAL ARTICLE CBP sensitizes v-myb-transformed monoblasts to differentiation inducers - Full text - MIT Libraries
S Jana, A Nemajerova, J Navratilova, P Jurdic, S … - Differentiation, 2005 - blackwell-synergy.com
... Fung, SM, Ramsay, G. and Katzen, AL (2003) MYB and CBP ... JD, Ponder, BA, Kouzarides,
T. and Caldas, C. (2000) Mutations truncating the EP300 acetylase in ...
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A transcription-factor-binding surface of coactivator p 300 is required for haematopoiesis - Full text - MIT Libraries
LH Kasper, F Boussouar, PA Ney, CW Jackson, J Rehg … - Nature, 2002 - nature.com
... Mutations truncating the EP300 acetylase in human cancers. Nature Genet. ... A functional
c-myb gene is required for normal murine fetal hepatic hematopoiesis. ...
Cited by 15 - Web Search - nature.com - adsabs.harvard.edu - ncbi.nlm.nih.gov - all 5 versions »

CBP truncating mutations in ovarian cancer - Full text - MIT Libraries
R Ward, M Johnson, V Shridhar, J van Deursen, FJ … - Journal of Medical Genetics, 2005 - jmedgenet.com
... 1 In particular, CBP, like its homologue EP300, enhances gene transcription by linking ...
the human T cell leukaemia virus (HTLV) Tax protein and v-myb to induce ...
Cached - Web Search - jmg.bmjjournals.com - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Functional Genomic Analysis of the Wnt-Wingless Signaling Pathway - Full text - MIT Libraries
R DasGupta, A Kaykas, RT Moon, N Perrimon, SC Maps … - Science, 2005 - sciencemag.org
... activity HFA06044 DRSC06044 CG11132 increased 9.8 >3 Myb DNA binding ND HFA18632
DRSC18632 CG11380 increased 3.81 >1.5 ND ND HFA14347 ...
Cited by 6 - Web Search - flyrnai.org - ncbi.nlm.nih.gov - all 4 versions »

CBP/p300 in cell growth, transformation, and development - Full text - MIT Libraries
RH Goodman, S Smolik - Development, 2000 - genesdev.org
... transcriptional regulators were shown subsequently shown to be modified by acetylation,
including EKLF, GATA-1, dTCF, NF-Y, TFIIE, TFIIF, HMGI(Y), c-myb, myo-D ...
Cited by 393 - Web Search - genesdev.org - genesdev.org - ncbi.nlm.nih.gov - all 5 versions »

MOLECULAR PATHOGENESIS OF PANCREATIC CANCER - Full text - MIT Libraries
DE Hansel, SE Kern, RH Hruban - Annual Review of Genomics and Human Genetics, 2003 - fluid.annualreviews.org
... 12p12, MYB at 6q24, and AKT2 at 19q13.1-q13.2; MYB and AKT2 ... Less frequently affected
genes include BRCA2, MKK4, EP300, STK11, ALK4/ACVR1B, ACVR2, TGFBR1, and ...
Cited by 10 - Web Search - fluid.annualreviews.org - nutr.annualreviews.org - ncbi.nlm.nih.gov - all 5 versions »

CBP and p300: versatile coregulators with important roles in hematopoietic gene expression
GA Blobel - J Leukoc Biol, 2002 - jleukbio.org
... differentiation and cell-cycle arrest (eg, GATA-1; see below) but also with factors
that promote cell-cycle progression and transformation (eg, Myb and PU.1 ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov - virologyj.com - Get it from MIT Libraries

Genetic and cytogenetic analyses of breast cancer yield different perspectives of a complex disease - Full text - MIT Libraries
P O’Connell - Breast Cancer Res. Treat, 2003 - springerlink.com
... CHK2 a Rad 53 homologue TSG, DNA repair 22q12.1 Both [22] EP300 E1A binding
protein TSG, chromatin remodeling 22q13 Both [60] a ...
Cited by 4 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov

Histone acetylation and disease - Full text - MIT Libraries
S Timmermann, H Lehrmann, A Polesskaya, A Harel- … - Cell. Mol. Life Sci, 2001 - springerlink.com
... a wide variety of transcription regulatory proteins, such as p53, GATA-1, HIV-1
Tat, c-Myb, HNF1 and HNF4 ... (2000) Mutations truncating the EP300 acety- lase in ...
Cited by 53 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

[BOOK] Molecular biology of cancer
F Macdonald, CHJ Ford, AG Casson - 2004 - print.google.com
Page 1. r ff 1 Page 2. V 1V L ) TEXT !Bloinformatics C A. Orengo, DT Jones
and JM Thornton (Eds) ISBN: 1 859960545 Published: November ...
Cited by 10 - Web Search - Get it from MIT Libraries - Library Search

p300/CBP proteins: HATs for transcriptional bridges and scaffolds - Full text - MIT Libraries
HM Chan, NB La Thangue - J. Cell Sci, 2001 - jcs.biologists.org
... Gu and Roeder, 1997b; Sakaguchi et al., 1998; Lui et al., 1999a), E2F-1, E2F-2 and
E2F-3 (Martinez-Balbás et al., 2000; Marzio et al., 2000), MYB (Tomita et al ...
Cited by 149 - Web Search - jcs.biologists.org - genetics.biol.ttu.edu - ncbi.nlm.nih.gov

Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu - Full text - MIT Libraries
A Goel, R Janknecht - Mol Cell Biol, 2003 - mcb.asm.org
... Mutations truncating the EP300 acetylase in human cancers. ... Effects of B-Myb on gene
transcription: phosphorylation-dependent activity and acetylation by p300. ...
Cited by 6 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

The Ewing’s sarcoma gene product functions as a transcriptional activator - Full text - MIT Libraries
KL Rossow, R Janknecht - Cancer Res, 2001 - cancerres.aacrjournals.org
... found to interact with transcription factors such as CREB, c-Myb, and the ... JD, Ponder
BA, Kouzarides T., Caldas C. Mutations truncating the EP300 acetylase in ...
Cited by 25 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

Histone modification enzymes: novel targets for cancer drugs
R Kristeleit, L Stimson, P Workman, W Aherne - Expert Opinion on Emerging Drugs, 2004 - dx.doi.org
... 95 90 - H3, H4 H3, H4 H4 Co-activators p53, E2F, MyoD, TFIIE, TFIIF c-myb MYST MOZ
MORF HBO1 Tip60 225 - - 60 H3 H2A, H3, H4 H3, H4 H2A, H3, H4 Leukaemogenesis ...
Web Search - extenza-eps.com - ashley-pub.com - ingentaconnect.com - all 8 versions »

Prediction of high risk Ewing's sarcoma by gene expression profiling - Full text - MIT Libraries
A Ohali, S Avigad, R Zaizov, R Ophir, S Horn-Saban … - Oncogene, 2004 - nature.com
... X06409 0.007728 DMTF1 Cyclin D -binding myb-like transcription factor 1 AF052102
0.002852 ... D50419 0.006313 EP300 E1A-binding protein p300 U01877 0.002852 ...
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Epigenetics and cancer - Full text - MIT Libraries
AH Lund, M van Lohuizen - Genes & Development, 2004 - genesdev.org
... The two closely related HATs, p300 and CBP, act as transcriptional cofactors for
a range of cellular oncoproteins, such as MYB, JUN, FOS, RUNX, BRCA1, p53, and ...
Cited by 11 - Web Search - dx.doi.org - genesdev.org - ncbi.nlm.nih.gov

Epigenetic and Chromatin Modifiers As Targeted Therapy of Hematologic Malignancies - Full text - MIT Libraries
KN Bhalla - J Clin Oncol, 2005 - jco.org
... 12,13,120-122 The two closely related HATs p300 and CBP are transcriptional co-factors
for several oncoproteins including p53, pRB, Myb, Jun, Fos, and RUNX. ...
Cited by 2 - Web Search - dx.doi.org - jco.org - ncbi.nlm.nih.gov

The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases - Full text - MIT Libraries
XJ Yang - Nucleic Acids Research, 2004 - nar.oupjournals.org
... for androgen receptor (159). Human MOF is part of a complex implicated in
activating the B-myb promoter (160). MOZ and MORF possess ...
Cited by 14 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »