Developing models of DiGeorge syndrome
JA Epstein - Trends Genet, 2001 - uphs.upenn.edu
... Pax3, Foxc1 and Foxc2 are clearly required for normal cardiovascular devel- opment,
yet cannot account for cardiovascular defects in patients with DiGeorge ...
Cited by 21 - View as HTML - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Human FOX gene family (Review). - Full text - MIT Libraries
M KATOH, M KATOH - INTERNATIONAL JOURNAL OF ONCOLOGY, 2004 - 147.52.72.117
... FOXC1, FOXC2, FOXE1, FOXE3, FOXL2, FOXN1, FOXP2 and FOXP3 genes are mutated in human
congenital ... FOXO1 gene is fused to PAX3 or PAX7 genes in rhabdomyosarcoma. ...
Cited by 4 - View as HTML - Web Search - ncbi.nlm.nih.gov

Functional interactions between alternatively spliced forms of Pax 6 in crystallin gene regulation … - Full text - MIT Libraries
BK Chauhan, Y Yang, K Cveklova, A Cvekl - Nucleic Acids Research, 2004 - pubmedcentral.nih.gov
... A significant proportion of genes encoding transcription factors (eg FOXC1, PAX2,
PAX3, PAX6, PITX2, PITX3, SIX6 and TBX1) are dosage-sensitive (3,32,53–56). ...
Cited by 2 - Web Search - nar.oxfordjournals.org - nar.oupjournals.org - ingentaconnect.com - all 7 versions »

A chicken model for DGCR6 as a modifier gene in the DiGeorge critical region - Full text - MIT Libraries
BP Hierck, DG Molin, MJ Boot, RE Poelmann, AC … - Pediatr. Res, 2004 - pedresearch.org
... endothelin converting enzyme-1 (27), transforming growth factor ß2 (28), mesenchyme
forkhead genes Mfh-1/Foxc2 (29) and Mf-1/Foxc1 (30), Pax3 (31), Semaphorin ...
Cited by 3 - Web Search - pedresearch.org - ncbi.nlm.nih.gov

Smooth muscle stem cells
KK Hirschi, MW Majesky - The Anatomical Record, 2004 - doi.wiley.com
... Smooth muscle differentiation in the neural crest lineage is controlled by a
combination of cell intrinsic factors, includ- ing Pax3, Tbx1, FoxC1, and serum ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Identification and characterization of human FOXN5 and rat Foxn5 genes in silico - Full text - MIT Libraries
M Katoh, M Katoh - Int J Oncol, 2004 - 147.52.72.117
... members of the Forkhead-box (FOX) transcription factor superfamily (1-3). FOXC1
mutations are ... FOXO1A gene is fused to PAX3 or PAX7 genes due to chromosomal ...
Cited by 25 - View as HTML - Web Search - ncbi.nlm.nih.gov

Molecular Determinants of Neural Crest Migration
KL MASCHHOFF, HS BALDWIN - American Journal of Medical Genetics (Semin. Med. Genet.), 2000 - doi.wiley.com
... Few human patients homozygous for PAX3 mutations have been examined, likely as the
result of ... MF-1 (FOXC1) is the mouse homologue of the human gene FKHL7, which ...
Cited by 19 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Neural crest and cardiovascular development: A 20-year perspective
MR Hutson, ML Kirby - Birth Defects Research Part C Embryo Today Reviews, 2003 - doi.wiley.com
... This mouse has a dys- functional Pax3 gene that leads to cardiac phenotypes similar
to those of the neural crest-ablated chick (Conway et al., 1997c). ...
Cited by 20 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Table 2. Gene Mutations Demonstrating Cardiac Phenotypes
N Phenotype - ahavj.ahajournals.org
... Foxc1 (Fkh1/forkhead box C1), Aortic arch abnormalities, 68. ... Ntf3 (neurotrophin 3),
PTA, IAA, CT defects, 108. Pax3 (paired box gene 3), PTA, CT defects, 109. ...
Web Search

The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for … - Full text - MIT Libraries
BS Mankoo, S Skuntz, I Harrigan, E Grigorieva, A … - Development, 2003 - dev.biologists.org
... Foxc1 and Foxc2 are both required for the formation of segmented somites, and may ...
of skeletal muscle (reviewed by Arnold and Braun, 2000 ), and Pax3 and Myf5 ...
Cited by 7 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch … - Full text - MIT Libraries
L Feiner, AL Webber, CB Brown, MM Lu, L Jia, P … - Development, 2001 - dev.biologists.org
... mRNAs for (A,B) Foxc1, (C,D) endothelin receptor A (EdnrA), or (E,F ... Pax3, retinoic
acid receptors, and connexin 43 are all expressed in cardiac neural crest ...
Cited by 52 - Web Search - dev.biologists.org - uphs.upenn.edu - ncbi.nlm.nih.gov

The Role of Neural Crest during Cardiac Development in a Mouse Model of DiGeorge Syndrome - Full text - MIT Libraries
L Kochilas, S Merscher-Gomez, MM Lu, V Potluri, J … - Developmental Biology, 2002 - uphs.upenn.edu
... Expression of several neural crest-specific genes, includ- ing Pax3 and EdnrA
(Clouthier et al., 1998; Epstein et al., 2000; Yanagisawa et al., 1998 ... Foxc1 (Figs ...
Cited by 21 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Program: Friday, October 10, 2003 - Full text - MIT Libraries
V Ling, JM Egly, A Kraemer, R Emeson, B Sollner- … - Molecular & Cellular Proteomics, 2003 - mcponline.org
... franciscana Yu Sun, Dalhousie University, Halifax, NS, Canada 123.7 Regulation of
FOXC1 Expression by PAX3, GLI2 and ß-Catenin During Myogenesis Josee Savage ...
Web Search - mcponline.org

PlexinA2 and semaphorin signaling during cardiac neural crest development - Full text - MIT Libraries
CB Brown, L Feiner, MM Lu, J Li, X Ma, AL Webber, … - Development, 2001 - dev.biologists.org
... Examples include Pax3 (Epstein, 1996 ), Endothelin receptor A (Ednra; Yanagisawa
et al., 1998 ... 43 (Cx43; also called Gjal; Lo et al., 1999 ), Foxc1 and Foxc2 ...
Cited by 34 - Web Search - uphs.upenn.edu - dev.biologists.org - ncbi.nlm.nih.gov

Molecular markers of cardiac endocardial cushion development - Full text - MIT Libraries
AD Gitler, MM Lu, YQ Jiang, JA Epstein, PJ Gruber - Developmental Dynamics, 2003 - doi.wiley.com
... The murine winged helix tran- scription factors, Foxc1 and Foxc2, are both required ...
Msx2 is an immedi- ate downstream effector of Pax3 in the development of ...
Cited by 6 - Web Search - uphs.upenn.edu - ncbi.nlm.nih.gov

Status of the Human Malformation Map: 2002
JC CAREY, DH VISKOCHIL - American Journal of Medical Genetics (Semin. Med. Genet.), 2002 - doi.wiley.com
... 108900 600584 5q34 NKX2E NK2 transcription factor, Drosophila, homolog of, E Axenfeld
anomaly 601090 601090 6p25 FOXC1 Forkhead, Drosophila, homolog-like 7 ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Chromosomal Abnormalities and Glaucoma: A Case of Congenital Glaucoma with Trisomy 8q22-Qter/ …
AC Cohn, LS Kearns, R Savarirayan, J Ryan, JE … - Ophthalmic Genetics, 2005 - taylorandfrancis.metapress.com
... and FOXC1, 23,24 were identified by mapping rearrangement breakpoints in glaucoma
patients, in addition to the PAX6 gene in aniridia which is also frequently ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the … - Full text - MIT Libraries
J Fang, SL Dagenais, RP Erickson, MF Arlt, MW … - Am J Hum Genet, 2000 - journals.uchicago.edu
... (1998) was caused by in- activation of FOXC1, as a ... S, Rauscher FJ III, Emanuel BS,
Rovera G, Barr FG (1993) Fusion of a fork head domain gene to PAX3 in the ...
Cited by 90 - Web Search - journals.uchicago.edu - ncbi.nlm.nih.gov

Transcriptional regulation of cardiac development: implications for congenital heart disease and … - Full text - MIT Libraries
JA Epstein, CA Buck - Pediatr Res, 2000 - pedresearch.org
... Using a neural crest-specific element in the Pax3 promoter to direct expression
of ... enzyme 1 (61) and by the winged helix transcription factors Foxc1 (Mf1) and ...
Cited by 19 - Web Search - pedresearch.org - ncbi.nlm.nih.gov

[CITATION] The embryology of the common arterial trunk
AC Gittenberger-de Groot, MM Bartelings, A Bogers, … - Prog Pediatr Cardiol, 2002
Cited by 4 - Web Search

REVIEW ARTICLES Transcriptional Regulation of Cardiac Development: Implications for Congenital Heart …
JA EPSTEIN, CA BUCK - PEDIATRIC RESEARCH, 2000 - uphs.upenn.edu
... Using a neural crest-specific element in the Pax3 promoter to direct expression
of ... enzyme 1 (61) and by the winged helix transcription factors Foxc1 (Mf1) and ...
View as HTML - Web Search - Get it from MIT Libraries

Development Gone Awry - Full text - MIT Libraries
CH Disease - Circulation Research, 2004 - circresaha.org
... Pax3-expressing neural crest derivatives populate the conotrunus in a rostral to ...
67 Mutations in two related forkhead transcription factors, Foxc1 and Foxc2 ...
Cached - Web Search - circres.ahajournals.org - ahavj.ahajournals.org - uphs.upenn.edu - all 8 versions »

A catalogue of gene expression in the developing kidney - Full text - MIT Libraries
K Schwab, LT Patterson, BJ Aronow, R Luckas, HC … - Kidney International, 2003 - blackwell-synergy.com
... transcription factor, was also expressed at elevated levels at E12.5. FOXc2 has
been implicated in the repression of GDNF signaling, with FOXc1 mutants showing ...
Cited by 9 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Fork head transcription factors
B Granadino, C Perez-Sanchez, J Rey-Campos - Current Genomics, 2000 - ingentaconnect.com
... For example, FOXC1 (FKHL7 or FREAC-3) has been involved in the Axenfeld-Rieger anomaly
[28]; fusion of FOXO1 Page 4. ... (FKHR) with the Pax3 or Pax7 genes by ...
Cited by 4 - Web Search

Identification and characterization of a novel human FOXK1 gene in silico. - Full text - MIT Libraries
JT HUANG, V LEE - INTERNATIONAL JOURNAL OF ONCOLOGY, 2004 - 147.52.72.117
... JM and Hogan BL: The murine winged helix transcription factors, Foxc1 and Foxc2 ... J,
Biegel JA, Rovera G and Emanuel BS: Rearrangement of the PAX3 paired box gene ...
View as HTML - Web Search - ncbi.nlm.nih.gov

GDNF acts through PEA3 to regulate cell body positioning and muscle innervation of specific motor … - Full text - MIT Libraries
G Haase, E Dessaud, A Garces, B de Bovis, M … - Neuron, 2002 - neuro.med.harvard.edu
... prevent cell markers Pax3, myogenin, and MyoD, and Sox10, a cell ... not cells
found at the base of the limb did not express Pax3, be ...
Cited by 21 - View as HTML - Web Search - ingentaconnect.com

The human T locus and spina bifida risk - Full text - MIT Libraries
LEJS Barbaux, K Hoess, SFAS Whitehead, LE Mitchell - Hum Genet, 2004 - springerlink.com
... sites for transcription factors that are know to be involved in development:
Hox1.3 (Carpenter 2002), the forkhead- related activators 3 and 4 (FOXC1 and FOXD1 ...
Web Search

New frontiers in molecular pediatric cardiology
E Dees, HS Baldwin - Curr Opin Pediatr, 2002 - co-pediatrics.com
... Several genes expressed by neural crest cells (foxc1, endothelin receptor A, plexinA2 ...
splotch embryos (a naturally occurring mouse mutation of the Pax3 gene and ...
Cited by 2 - Web Search - co-pediatrics.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal … - Full text - MIT Libraries
MS Ota, DAF Loebel, MP O'Rourke, N Wong, B Tsoi, … - Developmental Dynamics, 2004 - doi.wiley.com
... 2C,D), Foxc1/ ... Fig. 3. A–P: The expression pattern of Bmp4 (A,B), Sim1 (C,D), Alx4
(E,F), En1 (G,H), Sox9 (I,J), Paraxis (K,L), Myf5 (M,N), and Pax3 (O,P) in ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Alx 4 and Msx 2 play phenotypically similar and additive roles in skull vault differentiation - Full text - MIT Libraries
I Antonopoulou, LA Mavrogiannis, AOM Wilkie, GM … - Journal of Anatomy, 2004 - blackwell-synergy.com
... at least partially interdependent in their calvarial osteogenic activity is in
accordance with the observation that both genes show Foxc1-dependent activation ...
Cited by 3 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Edd, the Murine Hyperplastic Disc Gene, Is Essential for Yolk Sac Vascularization and … - Full text - MIT Libraries
DN Saunders, SL Hird, SL Withington, SL Dunwoodie, … - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... protein calmyrin inhibits the transcriptional and DNA-binding activity of Pax3. ... 2001.
The murine winged helix transcription factors, Foxc1 and Foxc2, are both ...
Cited by 2 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

Developmental Expression of Transcription Factors
AIP Tacc - acta.uta.fi
Page 1. Developmental Expression of Transcription Factors Studies on Fox Proteins
FoxF1, FoxF2 and FoxE3, BHLH-PAS Proteins Arnt and Arnt2 and Novel ...
Web Search