Human Genome and Diseases: Review Transcription factor GATA3 and the human HDR syndrome - Full text - MIT Libraries
H Van Esch, K Devriend - Cell. Mol. Life Sci, 2001 - springerlink.com
... GATA3, GATA1 and GATA2 are necessary factors for haematopoiesis: gene disruption
of any of them results in major haematopoietic defects in the mouse [19, 20, 45 ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

GATA3 haplo-insufficiency causes human HDR syndrome - Full text - MIT Libraries
H Van Esch, P Groenen, MA Nesbit, S Schuffenhauer, … - Nature, 2000 - nature.com
... Rivolta, MN & Holley, MC GATA3 is downregulated during hair cell ... Familial
dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1. ...
Cited by 60 - Web Search - nature.com - ncbi.nlm.nih.gov

Functional Analysis of a Novel GATA3 Mutation in a Family with the Hypoparathyroidism, Deafness, and … - Full text - MIT Libraries
A Zahirieh, MA Nesbit, A Ali, K Wang, N He, M … - The Journal of Clinical Endocrinology & Metabolism - jcem.endojournals.org
... The same larger band can also be occasionally seen in association with WT GATA3
and GATA1 (8). The nature of these different GATA3-DNA species is unknown, but ...
Web Search - jcem.endojournals.org - ncbi.nlm.nih.gov

Functional Analysis of a Novel GATA3 Mutation in a Family with the
D Hypoparathyroidism, RDHDR Syndrome - jcem.endojournals.org
... type GATA3 and GATA1 (8). The nature of these different GATA3 – DNA species is unknown,
but they may represent binding of more than one GATA3 molecule. ...
Web Search

TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell … - Full text - MIT Libraries
Y Ono, N Fukuhara, O Yoshie - Mol. Cell. Biol, 1998 - mcb.asm.org
... as SP1 (38). Like this GATA1 mutant, the C-terminal Zn finger of GATA3
was mutated to generate GATA3-CFM. Whole-cell lysates of ...
Cited by 39 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Identification of a novel insertion mutation in GATA 3 with HDR syndrome - Full text - MIT Libraries
Y Mino, T Kuwahara, T Mannami, K Shioji, K Ono, N … - Clinical and Experimental Nephrology, 2005 - springerlink.com
... Thus, the mutation re- ported in the present study would completely abolish the
DNA-binding ability of GATA3. GATA1, -2 and -3 are critically involved in ...
Web Search - ncbi.nlm.nih.gov

Structure and expression of the human GATA3 gene - Full text - MIT Libraries
MC Labastie, D Bories, C Chabret, JM Gregoire, S … - Genomics, 1994 - ncbi.nlm.nih.gov
... The two human GATA3 zinc fingers are encoded by two separate exons highly conserved
with those of GATA1, but no other structural homologies between these two ...
Cited by 14 - Web Search

GATA3 is downregulated during hair cell differentiation in the mouse cochlea
MN Rivolta, MC Holley - J Neurocytol, 1998 - springerlink.com
... GATA1 is essential for erythroid cell development (Pevny et al., 1991), GATA2 is
in ... of mast cells and megakaryocytes (Tsai et al., 1994), while GATA3 is im ...
Cited by 16 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4 - Full text - MIT Libraries
I Pata, M Studer, JH van Doorninck, J Briscoe, S … - Development, 1999 - dev.biologists.org
... cells and in primitive erythropoiesis, whereas GATA1 has a role in definitive
erythropoiesis (Pevny et al., 1991; Tsai et al., 1994). GATA3 is essential for T ...
Cited by 31 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Self-Association of Gata1 Enhances Transcriptional Activity In Vivo in Zebra Fish Embryos - Full text - MIT Libraries
K Nishikawa, M Kobayashi, A Masumi, SE Lyons, BM … - Mol. Cell. Biol, 2003 - mcb.asm.org
... in the zebra fish Gata1 protein, which are important for self-association, are
conserved among vertebrate hematopoietic Gata factors Gata1, Gata2, and Gata3. ...
Cited by 5 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Gata2 and Gata3: novel markers for early embryonic polarity and for non-neural ectoderm in the chick … - Full text - MIT Libraries
G Sheng, CD Stern - Mech. Dev, 1999 - sternlab.anat.ucl.ac.uk
... Gata family of zinc ®nger transcription factors contains six members, Gata1±6. Gata ...
More recently, Gata2 and Gata3 have also been suggested to play a role in ...
Cited by 13 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Decreased GATA3 mRNA Expression in Human T-cell Lymphotropic Virus Type 1 (HTLV-1) Infection
SC Gilli, TS Salles, ST Saad - Scand J Infect Dis, 2000 - dx.doi.org
... DISCUSSION The transcription factor GATA3 was first identified by its DNA sequence
homology to GATA1, the first member of the GATA family of transcription ...
Cited by 1 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Hematopoietic regulatory domain of gata1 gene is positively regulated by GATA1 protein in zebrafish … - Full text - MIT Libraries
M Kobayashi, K Nishikawa, M Yamamoto - Development, 2001 - dev.biologists.org
... It is intriguing to note that not only the gata1 gene, but other family members
of the hematopoietic GATA factor family, gata2 and gata3, contain the first ...
Cited by 17 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The Runx1 Transcription Factor Inhibits the Differentiation of Naive CD4 T Cells into the Th2 … - Full text - MIT Libraries
O Komine, K Hayashi, W Natsume, T Watanabe, Y Seki … - The Journal of Experimental Medicine - intl.jem.org
... Recently, repressor of GATA (ROG) and friend of GATA1 (FOG1) were shown to bind
to GATA3 and were thereby characterized as GATA3-repressing proteins (35, 36). ...
Cited by 13 - Web Search - jem.org - dx.doi.org - ncbi.nlm.nih.gov - all 8 versions »

Selective impairment of platelet activation to collagen in the absence of GATA1 - Full text - MIT Libraries
SC Hughan, Y Senis, D Best, A Thomas, J Frampton, … - Blood, 2005 - bloodjournal.org
... underlying this process are tightly regulated by lineage-affiliated transcription
factors exemplified by the hematopoietic GATA proteins (GATA1-GATA3). ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Role of NFAT proteins in IL13 gene transcription in mast cells - Full text - MIT Libraries
S Monticelli, DC Solymar, A Rao - J. Biol. Chem, 2004 - jbc.org
... 6A). Western blotting of cell lysates showed that T cells express GATA3 but not
GATA1 and GATA2, whereas mast cells express GATA1 and GATA2 but not GATA3 (Fig. ...
Cited by 2 - Web Search - dx.doi.org - ijmm.org - ncbi.nlm.nih.gov - all 5 versions »

GATA1 Function, a Paradigm for Transcription Factors in Hematopoiesis - Full text - MIT Libraries
R Ferreira, K Ohneda, M Yamamoto, S Philipsen - Mol Cell Biol, 2005 - mcb.asm.org
... GATA1, GATA2, and GATA3 belong to the hematopoietic subfamily, since they are
expressed mainly in the hematopoietic system (Fig. 2) (121). ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 … - Full text - MIT Libraries
V Valverde-Garduno, B Guyot, E Anguita, I Hamlett, … - Blood, 2004 - bloodjournal.org
... Differences in the chromatin structure and cis-element organization of the human
and mouse GATA1 loci: implications for cis-element identification. ...
Cited by 3 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov

Transcription factor expression in cell lines derived from natural killer-cell and natural killer- …
Y Matsuo, HG Drexler, A Harashima, A Okochi, N … - Hum Cell, 2004 - ncbi.nlm.nih.gov
... The present study analyzed the expression of the following 13 TFs: AML1, CEBPA,
E2A, ETS1, GATA1, GATA2, GATA3, IKAROS, IRF1, PAX5, PU1, TBET and TCF1 in 7 ...
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Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPalpha and GATA … - Full text - MIT Libraries
B Heavey, C Charalambous, C Cobaleda, M Busslinger - EMBO J, 2003 - embojournal.npgjournals.com
... in the spleen (Figure 1). In summary, these results indicate that the transcription
factors GATA2 and GATA3, in contrast to GATA1 and C/EBP , can efficiently ...
Cited by 10 - Web Search - nature.com - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Transcriptional activity of TAL 1 in T cell acute lymphoblastic leukemia(T-ALL) requires RBTN 1 or-2 … - Full text - MIT Libraries
Y Ono, N Fukuhara, O Yoshie - J Biol Chem, 1997 - jbc.org
... on a reporter gene linked to multiple GATA3-binding sites and to block transactivation
of the same reporter gene by wild type GATA1, GATA2, or GATA3 (35). ...
Cited by 18 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Characterization of GATA 3 Mutations in the Hypoparathyroidism, Deafness, and Renal Dysplasia(HDR) … - Full text - MIT Libraries
MA Nesbit, MR Bowl, B Harding, A Ali, A Ayala, C … - J Biol Chem, 2004 - jbc.org
... 37), and because the N-terminal zinc fingers of GATA1 and GATA3 are over 90% identical,
we modeled the position of the GATA3 mutants on this framework. ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A tissue-specific knockout reveals that Gata 1 is not essential for Sertoli cell function in the … - Full text - MIT Libraries
F Lindeboom, N Gillemans, A Karis, M Jaegle, D … - Nucleic Acids Research, 2003 - nar.oupjournals.org
... Finally, a transgene driving expression of Gata2 or Gata3 cDNA under Gata1 regulatory
sequences can rescue the embryonic lethal phenotype of Gata1 knockdown ...
Cited by 5 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - dspace.ubib.eur.nl - all 11 versions »

PEST motifs are not required for rapid calpain-mediated proteolysis of c-fos protein - Full text - MIT Libraries
S Carillo, M Pariat, AM Steff, I Jariel-Encontre, … - Biochem. J, 1996 - biochemj.org
... Testing the susceptibility of PEST motif-bearing and non-bearing transcription factors
including GATA1, GATA3, Myo D, c-erbA, Tal-1 and Sry, demonstrates that ...
Cited by 19 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

1 ere Session: ANGIOGENESE
W Christopher - institut.cochin.inserm.fr
... These factors are expressed in a developmental hierarchy: GATA2 is required for
the proliferation of early precursor cells while GATA1 and GATA3 are ...
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STAT6-Dependent Differentiation and Production of IL-5 and IL-13 in Murine NK2 Cells - Full text - MIT Libraries
T Katsumoto, M Kimura, M Yamashita, H Hosokawa, K … - The Journal of Immunology, 2004 - jimmunol.org
... similar results. Expression of GATA3, GATA2, GATA1, ROG, granzyme B, perforin
1, and IL-12R 2 in differentiated NK subsets. Next, to ...
Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

In Silico Identification of Regulatory Elements of GRIN 1 Genes
MK Mejia-Guerra, LR Lareo - Omics A Journal of Integrative Biology, 2005 - dx.doi.org
... (2 copies) HNF-3b (2 copies) 700 to 600 GATA1, GATAX, CdxA SRY Mkx-2 GATA2, GATA1
GATA3 600 to 500 GATA1 Sp1 Mkx-2 500 to 400 E47 c-Ets STATx E12 STATx ...
Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Loss of LKLF function results in embryonic lethality in mice
MA Wani, RT Means Jr, JB Lingrel - Transgenic Research, 1998 - ncbi.nlm.nih.gov
... cells. Expression of other erythroid specific genes such as EKLF, GATA1
and GATA3 is unaltered in these animals. These findings ...
Cited by 20 - Web Search - ncbi.nlm.nih.gov - csa.com - Get it from MIT Libraries

Vergleichende funktionelle und molekulare Charakterisierung humaner Zelllinienmodelle aus dem …
I Mathematik, S Physik - edoc.ub.uni-muenchen.de
... In der Rh123low Subpopulation wurde im Gegensatz zur Rh123high Population eine
Expression von BMP4, GATA1, GATA3 nachgewiesen, die essentiell für die ...
Cached - Web Search

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5 - Full text - MIT Libraries
AOP Nature - Nature, 2003 - nature.com
... Gata1, Gata2 and Gata3 are expressed predominantly in haematopoietic cells, and
heterozygous mutations of GATA1 and GATA3 cause human blood disorders and organ ...
Web Search - nature.com

A Placenta-Specific Enhancer of the Human Syncytin Gene - Full text - MIT Libraries
YH Cheng, S Handwerger, S Handwerger - BIOLOGY OF REPRODUCTION, 2005 - biolreprod.org
... Primer sequences used for detection of GATA1, GATA2, GATA3 and human ... Table 3.
RT-PCR of the GATA1, GATA2, GATA3, and GAPD mRNAs yielded products ...
Web Search - biolreprod.org - ncbi.nlm.nih.gov

Abnormalities of the genitourinary tract in female mice lacking GATA5 - Full text - MIT Libraries
JD Molkentin, KM Tymitz, JA Richardson, EN Olson - Mol Cell Biol, 2000 - mcb.asm.org
... GATA1, GATA2, and GATA3 are expressed predominantly in hematopoietic cell
lineages. GATA1 is required for erythroid and megakaryocyte ...
Cited by 36 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

Regulation of Th2 cytokine gene transcription
P LAVENDER, D COUSINS, T LEE - Chem. Immunol, 2000 - content.karger.com
... there have been no reports of direct interactions between GATA3 and co-activators
with inherent histone acetyltransferase (HAT) activ- ity, GATA1 has recently ...
Cited by 2 - Web Search - content.karger.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

protein GATAl - Full text - MIT Libraries
H OSADA, G GRUTZ, H AXELSON, A FORSTER, TH … - Proc. Natl. Acad. Sci. USA, 1995 - pnas.org
... complexes involving RBTN2, TAL1, and GATA1, together with E47, the ... (12). The
various properties of GATA1, rbtn2, and tall genes suggest ...
Cited by 85 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Ci-GATAa, aGATA-class gene from the ascidianCiona intestinalis: Isolation and developmental … - Full text - MIT Libraries
P D'Ambrosio, A Fanelli, M Pischetola, A Spagnuolo - Developmental Dynamics, 2003 - doi.wiley.com
... Members of the first group, GATA1, GATA2, GATA3, are implicated in the specification
of blood cell lineages (Pevny and Si- mon, 1991; Tsai et al., 1994 ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Multiple roles for Gata5 in zebrafish endoderm formation - Full text - MIT Libraries
JF Reiter, Y Kikuchi, DY Stainier - Development, 2001 - dev.biologists.org
... While gata1, gata2 and gata3 function predominantly in hematopoietic development
(reviewed by Orkin and Zon, 1997), gata4, gata5 and gata6 are expressed in ...
Cited by 38 - Web Search - ucsf.edu - dev.biologists.org - ncbi.nlm.nih.gov

Partially overlapping expression of Gata 2 and Gata 3 during inner ear development - Full text - MIT Libraries
K Lillevaeli, T Matilainen, A Karis, M Salminen - Developmental Dynamics, 2004 - doi.wiley.com
... Gata2 and Gata3 belong to the Gata family of zinc finger domain transcription factors
(Gata1–6) in vertebrates that bind to a consensus “GATA” DNA ...
Web Search - ncbi.nlm.nih.gov

Molecular cloning and characterization of the GATA 1 cofactor human FOG 1 and assessment of its … - Full text - MIT Libraries
K Freson, C Thys, C Wittewrongel, J Vermylen, M … - Human Genetics, 2003 - springerlink.com
... a much lesser extent also in erythro- cytes), FOG1 not only binds GATA1 but also
GATA2. In CD4+ T cells FOG1 has recently shown to repress GATA3 activity (Zhou ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... CDPCR3HD PBX1 1177.3 FREAC7 GATA1 153.0 CDP GATA1 52.0 P300 SREBP1 27.9 MZF1
SP1 1089.2 CREBP1 XBP1 146.8 GATA3 NFY 51.9 AML1 E47 27.3 ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

GATA 4 mutations cause human congenital heart defects and reveal an interaction with TBX 5 - Full text - MIT Libraries
V Garg, IS Kathiriya, R Barnes, MK Schluterman, IN … - Nature, 2003 - nature.com
... due to an inherited mutation in GATA1. Nature Genet. 24, 266-270 (2000) | Article |
PubMed | ISI | ChemPort |. 16. Van Esch, H. et al. GATA3 haplo-insufficiency ...
Cited by 65 - Web Search - nature.com - tagc.univ-mrs.fr - ncbi.nlm.nih.gov - all 5 versions »

Phosphorylation of GATA2 by Akt Increases Adipose Tissue Differentiation and Reduces Adipose Tissue … - Full text - MIT Libraries
R Menghini, V Marchetti, M Cardellini, ML Hribal, … - Circulation, 2005 - circ.ahajournals.org
... properties. An Akt consensus motif was reported to be common to GATA1, GATA2,
and GATA3 and conserved among human, rat, and mouse. 20 ...
Web Search - circulationaha.org - circ.ahajournals.org - ncbi.nlm.nih.gov - all 5 versions »

Structure and transcriptional regulation of human a-mannosidase 11"(a-mannosidase I1 isotype) gene
MM Ryosuke OGAWA, MN FUKUDA, K Shinichi, IM … - Eur. J. Biochem, 1996 - blackwell-synergy.com
... (Eul: J. Biochem. 242) 449 -1068 TACCATAAAG TAGGTAGTTT ATCAACAACA eMyb HAPF1
NF-KB GATA3 GAAATGTATT TTCTCACAGT TATGGAGGCT GGAAAGTCCA TOATAAGGCA Am GATA1.2 ...
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Genomic approaches to identifying transcriptional regulators of osteoblast differentiation - Full text - MIT Libraries
J Stains, R Civitelli - Genome Biology, 2003 - pubmedcentral.nih.gov
... In addition to HOXB6, the expression of GATA1, GATA3 and the Kruppel-like factor
KLF1 increases during osteogenic differentiation, thus offering new clues as ...
Web Search - genomebiology.com - citebase.eprints.org - dx.doi.org - all 7 versions »

Molecular heterogeneity in AML/MDS patients with 3 q 21 q 26 rearrangements
I Lahortiga, I Vazquez, X Agirre, MJ Larrayoz, JL … - Genes Chromosomes and Cancer, 2004 - doi.wiley.com
... WGATAR (Orkin, 1992). Among these genes, GATA1, GATA2, and GATA3 play
crucial roles in hematopoiesis. GATA1 is highly expressed ...
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Cooperation between the GATA and RUNX factors Serpent and Lozenge during Drosophila hematopoiesis - Full text - MIT Libraries
L Waltzer, G Ferjoux, L Bataille, M Haenlin - The EMBO Journal, 2003 - embojournal.npgjournals.com
... megakaryocytoses. Finally, RUNX1 is coexpressed with GATA1, GATA2 or GATA3 at
different stages of hematopoiesis (Speck and Gilliland, 2002). ...
Cited by 7 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 6 versions »

Gata4 regulates testis expression of Dmrt1 - Full text - MIT Libraries
N Lei, LL Heckert - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... noted. Antibodies for Gata1, Gata2, Gata3, and Gata4 were purchased from Santa
Cruz Biotechnology, Inc. (Santa Cruz, Calif.). Antibodies ...
Cited by 3 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Embryonic stem cell models of development
KS O’Shea - Anat Rec (New Anat), 1999 - doi.wiley.com
... Hematopoiesis in GATA1- null ES can be restored by expression of either mouse or
chick GATA1 bind- ing proteins, or by GATA3 or GATA4, 51 illustrating the ...
Cited by 42 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem … - Full text - MIT Libraries
S Gerecht-Nir, JE Dazard, M Golan-Mashiach, S … - Developmental Dynamics, 2005 - doi.wiley.com
... 2003), CD45 (Mikkola et al., 2003; Ferkowicz et al., 2003), and transcrip- tion
factors TAL1, LMO2, GATA1, GATA2, and GATA3, although up-reg- ulation of the ...
Cited by 2 - Web Search - weizmann.ac.il - weizmann.ac.il - ncbi.nlm.nih.gov

Mutation of GATA 3 in human breast tumors - Full text - MIT Libraries
J Usary, V Llaca, G Karaca, S Presswala, M Karaca, … - Oncogene, 2004 - nature.com
... KRRL K IKP PL d Human GATA1 Human GATA2 Xenopus GATA2 Zebrafish GATA3 Chicken
NF-E1 Mouse GATA3 Human GATA3 Ull-214 Ull-030 MCF-7 BR00-0587 BR99-0348 Ull-011 ...
Web Search - genome.unc.edu - ncbi.nlm.nih.gov

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor … - Full text - MIT Libraries
Y Fujiwara, CP Browne, K Cunniff, SC Goff, SH … - Developmental Biology, 1996 - dx.doi.org
... S. Philipsen, and D. Whyatt Homotypic signalling regulates Gata1 activity in the ...
J. Sampson, AJ Williams, and RV Thakker Characterization of GATA3 Mutations in ...
Cited by 165 - Web Search - pnas.org - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 7 versions »