The Runx1 Transcription Factor Inhibits the Differentiation of Naive CD4 T Cells into the Th2 … - Full text - MIT Libraries
O Komine, K Hayashi, W Natsume, T Watanabe, Y Seki … - The Journal of Experimental Medicine - intl.jem.org
... Key Words: GATA3 • Runx1 • Th2 • T lymphocytes • transcription factor. Introduction. ...
We also tried cotransduction of GATA3 and Runx1 into CD4 + T cells. ...
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A RUNX trio with a taste for autoimmunity - Full text - MIT Libraries
ME Alarcon-Riquelme - Nature Genetics, 2003 - nature.com
... Using conditional systems, it has become evi- dent that RUNX1 and RUNX3 also ... a
T-helper-2 cell phenotype by regulating the transcription factor GATA3, key in ...
Cited by 11 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The collagen-mitochondria connection - Full text - MIT Libraries
R Rizzuto - Nature Genetics, 2003 - nature.com
... Using conditional systems, it has become evi- dent that RUNX1 and RUNX3 also ... a
T-helper-2 cell phenotype by regulating the transcription factor GATA3, key in ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Functional Domains of Runx1 Are Differentially Required for CD4 Repression, TCR {beta} Expression, … - Full text - MIT Libraries
M Kawazu, T Asai, M Ichikawa, G Yamamoto, T Saito, … - The Journal of Immunology, 2005 - jimmunol.org
... The Runx1 transcription factor inhibits the differentiation of naive CD4 + T cells
into the Th2 lineage by repressing GATA3 expression. J. Exp. Med. 198:51. ...
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Regulation of the Murine D {delta} 2 Promoter by Upstream Stimulatory Factor 1, Runx1, and c-Myb - Full text - MIT Libraries
J Carabana, E Ortigoza, MS Krangel - The Journal of Immunology, 2005 - jimmunol.org
Copyright © 2005 by The American Association of Immunologists Regulation of the
Murine D 2 Promoter by Upstream Stimulatory Factor 1, Runx1, and c-Myb 1. ...
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A complex linkage in the developmental pathway of endothelial and hematopoietic cells
SI Nishikawa - Curr Opin Cell Biol, 2001 - cbi.pku.edu.cn
... All of the observations summarized above are consistent with the notion that Runx1
is expressed in hemogenic ECs or their ... [16] observed GATA3 expression in ...
Cited by 19 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila … - Full text - MIT Libraries
E Ogawa, M Maruyama, H Kagoshima, M Inuzuka, J Lu, … - Proceedings of the National Academy of Sciences - pnas.org
... Kubo, and M. Satake The Runx1 Transcription Factor Inhibits the Differentiation
of Naive CD4+ T Cells into the Th2 Lineage by Repressing GATA3 Expression J. Exp ...
Cited by 272 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus - Full text - MIT Libraries
M Alarcon-Riquelme - Arthritis Res Ther, 2004 - citebase.eprints.org
... The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells
into the Th2 lineage by repressing GATA3 expression" J Exp Med 198 51-61. ...
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Adult and embryonic blood and endothelium derive from distinct precursor populations which are … - Full text - MIT Libraries
M Walmsley, A Ciau-Uitz, R Patient - Development, 2002 - dev.biologists.org
... Xaml, the Xenopus homologue of the haematopoietic progenitor gene, AML1/Runx1, which
is ... GATA2 and T4-globin (Walmsley et al., 1994 ); GATA3 (Bertwistle et al ...
Cited by 13 - Web Search - dx.doi.org - dev.biologists.org - ncbi.nlm.nih.gov - all 5 versions »

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and … - Full text - MIT Libraries
Q Wang, T Stacy, M Binder, M Marin-Padilla, AH … - Developmental Biology, 1996 - dx.doi.org
... Kubo, and M. Satake The Runx1 Transcription Factor Inhibits the Differentiation
of Naive CD4+ T Cells into the Th2 Lineage by Repressing GATA3 Expression J. Exp ...
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Cooperation between the GATA and RUNX factors Serpent and Lozenge during Drosophila hematopoiesis - Full text - MIT Libraries
L Waltzer, G Ferjoux, L Bataille, M Haenlin - The EMBO Journal, 2003 - embojournal.npgjournals.com
... megakaryocytoses. Finally, RUNX1 is coexpressed with GATA1, GATA2 or GATA3 at
different stages of hematopoiesis (Speck and Gilliland, 2002). ...
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Gene Expression Profiling and Microarrays Gene expression profiling of leukemic cell lines reveals …
A Andersson, P Eden, D Lindgren, J Nilsson, C … - Leukemia, 2005 - nature.com
... T-cell ALL comparison, the transcription factor and lineage regulator GATA3 and
the ... cell lines with identical genetic aberrations (P 0.002): RUNX1/CBFA2T1, 35 ...
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Overexpression of the Runx3 Transcription Factor Increases the Proportion of Mature Thymocytes of … - Full text - MIT Libraries
K Kohu, T Sato, S Ohno, K Hayashi, R Uchino, N Abe … - The Journal of Immunology, 2005 - jimmunol.org
... It must be noted, though, that the enforced expression of Runx1 in a fetal ... GATA3
is a positive regulator that boosts thymocytes toward the CD4 lineage (28, 29 ...
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Runx 1 Is Expressed in Adult Mouse Hematopoietic Stem Cells and Differentiating Myeloid and Lymphoid … - Full text - MIT Libraries
TE North, T Stacy, CJ Matheny, NA Speck, MFTR de … - Stem Cells, 2004 - intl-stemcells.alphamedpress.org
... The Runx1 transcription factor inhibits the differentiation of naive CD4 +
T cells into the Th2 lineage by repressing GATA3 expression. ...
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Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors - Full text - MIT Libraries
ATLSTC Containing, RAMHCCI Expression - Biochemistry, 1998 - dx.doi.org
... Kubo, and M. Satake The Runx1 Transcription Factor Inhibits the Differentiation
of Naive CD4+ T Cells into the Th2 Lineage by Repressing GATA3 Expression J. Exp ...
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Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors - Full text - MIT Libraries
F LOMBARDO, D KOMATSU, M HADJIARGYROU - Biochemistry, 1998 - pnas.org
... Kubo, and M. Satake The Runx1 Transcription Factor Inhibits the Differentiation
of Naive CD4+ T Cells into the Th2 Lineage by Repressing GATA3 Expression J. Exp ...
Web Search

GEArray S Series Mouse Autoimmune and Inflammatory Response Gene Array: AR-SAMM-602.3
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.com
... Egr1, Egr2, Egr3, Elk1, Elk3, Fkbp1b, Fos, Fosb, Fosl1, Fosl2, Gata3, Gata4, Icos ...
Nfkbib, Nfkbie, Nfkbil1, P300-ESTs, Raf1, Rel, Rela, Relb, Runx1, Runx2, Sp1 ...
View as HTML - Web Search - eurogentec.be

GEArray S Series Human Autoimmune and Inflammatory Response Gene Array: AR-SAHS-602
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.be
... ELK3, EP300, FKBP1B, FLJ14639 (NIP45), FOS, FOSL1, FOSL2, FOXP3, GATA3, GATA4, GRLF1 ...
NFKBIE, NFKBIL1, NFKBIL2, NFRKB, RAF1, REL, RELA, RELB, RUNX1, RUNX2, SP1 ...
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Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem … - Full text - MIT Libraries
S Gerecht-Nir, JE Dazard, M Golan-Mashiach, S … - Developmental Dynamics, 2005 - doi.wiley.com
... 13 GATA2 GATA binding protein 2 14 GATA3 GATA binding protein 3 ... 6 GATA1 GATA
binding protein 1 7 RUNX1 Runt-related transcription factor 1 ...
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The emergence of definitive hematopoietic stem cells in the mammal.
E Dzierzak, KL Medina, H Singh, MH Baron, ST … - Current Opinion in Hematology-, 2005 - co-hematology.com
... Indeed, this is suggested from HSC studies in the embryos haploinsufficient
for Runx1 and Gata2 transcription factors [10,11•]. ...
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CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid … - Full text - MIT Libraries
GA Blobel, T Nakajima, R Eckner, M Montminy, SH … - Biochemistry, 1998 - dx.doi.org
... Racke, M. Mogass, R. Khetawat, LL Delehanty, and AN Goldfarb RUNX1 and GATA ... M. Taniguchi,
and T. Nakayama Identification of a Conserved GATA3 Response Element ...
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Progress in Hematology
T Yamagata, K Maki, K Mitani - Int J Hematol, 2005 - cardenjennings.metapress.com
... The Runx1 transcription factor inhibits the differentiation of naive CD4 + T cells
into the Th2 lineage by repressing GATA3 expression. J Exp Med. ...
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CD4/CD8-LINEAGE DIFFERENTIATION IN THE THYMUS: FROM NUCLEAR EFFECTORS TOMEMBRANE SIGNALS - Full text - MIT Libraries
R Bosselut - molecules - nature.com
... the identification of transcription factors required for CD4 gene silencing by
CD8-lineage cells (RUNX3) or for CD4 + T-cell differentiation (GATA3), and a ...
Cited by 4 - Web Search - nature.com - ncbi.nlm.nih.gov

The‘definitive’(and‘primitive’) guide to zebrafish hematopoiesis - Full text - MIT Libraries
AJ Davidson, LI Zon - Oncogene, 2004 - nature.com
... Transcripts for the zebrafish runx1 orthologue are found in the ventral wall of ... detected
by examining the expression of genes such as ikaros, gata3, lck, and ...
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The zinc finger transcription factor Th-POK regulates CD 4 versus CD 8 T-cell lineage commitment - Full text - MIT Libraries
X He, X He, VP Dave, Y Zhang, X Hua, E Nicolas, W … - Nature, 2005 - nature.com
Page 1. The zinc finger transcription factor Th-POK regulates CD4 versus CD8
T-cell lineage commitment Xiao He 1 *, Xi He 1 *, Vibhuti ...
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The Gene SCL is Expressed during Early Hematopoiesis and Encodes a Differentiation-Related DNA- … - Full text - MIT Libraries
CG Begley, PD Aplan, SM Denning, BF Haynes, TA … - Blood, 2005 - pnas.org
... C. Hogan, L. Carlsson, N. Speck, J. Palis, and G. Keller Runx1 is essential ... in
T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3 Mol. Cell. ...
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Dynamic repositioning of CD4 and CD8 genes during T cell development - Full text - MIT Libraries
S Delaire, YH Huang, SW Chan, EA Robey - J. Exp. Med, 2004 - jem.org
... to examine the relationship between the activity of factors such as GATA3 and the ...
Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis. ...
Cited by 3 - Web Search - dx.doi.org - jcb.org - ncbi.nlm.nih.gov - all 5 versions »

Hematopoietic, angiogenic and eye defects in Meis 1 mutant animals - Full text - MIT Libraries
T Hisa, SE Spence, RA Rachel, M Fujita, T Nakamura … - The EMBO Journal, 2004 - embojournal.npgjournals.com
... Meis1 appears to act later in embryonic development than other transcription factors
such as GATA3 (Pandolfi et al, 1995), RUNX1 (Okuda et al, 1996; Wang et al ...
Cited by 9 - Web Search - nature.com - embojournal.npgjournals.com - ncbi.nlm.nih.gov

Both 5' and 3' flanks regulate Zebrafish brain-derived neurotrophic factor gene expression - Full text - MIT Libraries
G Heinrich, C Pagtakhan - BMC Neuroscience, 2004 - biomedcentral.com
... AML-1a were found. AML-1, also known as Runx1, contains a runt type of DNA binding
domain [29]. Runx1 must form a dimer with CBFβ to recognize and stably ...
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CD4-CD8 lineage commitment: an inside view - Full text - MIT Libraries
DJ Kappes, X He, X He - Nature Immunology, 2005 - nature.com
... at the SP CD8 stage, as gene targeting of Runx3 leads to derepression of Cd4 in
many or most SP CD8 cells, whereas individual deletion of Runx1 and Runx2 does ...
Web Search - nature.com

Deranged Early T Cell Development in Immunodeficient Strains of Nonobese Diabetic Mice - Full text - MIT Libraries
MA Yui, EV Rothenberg - The Journal of Immunology, 2004 - jimmunol.org
... 31); another transcription factor critical for T cell development, Gata3 (32, 33 ...
Bim, Cflar/Flip, and Fadd), other transcription factors (Id2, Id3, Runx1, and PU ...
Cited by 1 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

T-bet Regulates the Terminal Maturation and Homeostasis of NK and V 14i NKT Cells
MJ Townsend, AS Weinmann, JL Matsuda, R Salomon, … - Immunity 20, 2004 - genomics.ucdavis.edu
Page 1. Immunity, Vol. 20, 477–494, April, 2004, Copyright 2004 by Cell Press
T-bet Regulates the Terminal Maturation and Homeostasis ...
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Children and adults with acute lymphoblastic leukaemia have similar gene expression profiles. - Full text - MIT Libraries
E Kuchinskaya, M Heyman, D Grander, M Linderholm, … - European Journal Of Haematology, 2005 - blackwell-synergy.com
... included into the study: 7 with MLL rearrangement, 8 with ETV6/RUNX1, 5 with ... which
corresponded to T-lineage leukaemia (p<0.0001), rearrangements of ETV6/RUNX1 ...
Web Search - blackwell-synergy.com - ejh.dk - ncbi.nlm.nih.gov

Using a Customized DNA Microarray for Expression Profiling of the Estrogen-Responsive Genes to … - Full text - MIT Libraries
S Terasaka, Y Aita, A Inoue, S Hayashi, M … - Environmental Health Perspectives, 2004 - earthscape.org
... PVR, QSCN6, RACGAP1, RAP1GAP, RCN1, RDH11, RHOC, RIP140, RSK, RUNX1, S100P, SCD ... Histone
deacetylase (HDAC6) –2.6 GATA-binding protein 3 (GATA3) –2.8 General ...
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Evolutionary Origins of Lymphocytes: Ensembles of T Cell and B Cell Transcriptional Regulators in a … - Full text - MIT Libraries
MK Anderson, R Pant, AL Miracle, X Sun, CA Luer, … - The Journal of Immunology, 2004 - jimmunol.org
... The Runx probe was generated from the DNA binding domain of a mouse Runx1 cDNA. ... GATA
primers were as follows: 3'-degGATA-YHKMN and 5'-deg-GATA3 (36). ...
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Absence of Yolk sac Hematopoiesis from Mice with a Targeted Disruption of the scl Gene - Full text - MIT Libraries
L Robb, I Lyons, R Li, L Hartley, F Kontgen, RP … - Proceedings of the National Academy of Sciences - pnas.org
... Home page, Blood Home page G. Lacaud, L. Gore, M. Kennedy, V. Kouskoff, P. Kingsley,
C. Hogan, L. Carlsson, N. Speck, J. Palis, and G. Keller Runx1 is essential ...
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WSX-1: A Key Role in Induction of Chronic Intestinal Nematode Infection - Full text - MIT Libraries
AJ Bancroft, NE Humphreys, JJ Worthington, H … - J Immunol, 2004 - jimmunol.org
... The Runx1 transcription factor inhibits the differentiation of naïve CD4 T cells
into the Th2 lineage by repressing GATA3 expression. J. Exp. Med. 198:51. ...
Cited by 8 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

A method to identify cDNAs based on localization of green fluorescent protein fusion products - Full text - MIT Libraries
K Misawa, T Nosaka, S Morita, A Kaneko, T Nakahata … - Proceedings of the National Academy of Sciences, 2000 - pnas.org
... Kubo, and M. Satake The Runx1 Transcription Factor Inhibits the Differentiation
of Naive CD4+ T Cells into the Th2 Lineage by Repressing GATA3 Expression J. Exp ...
Cited by 36 - Web Search - pubmedcentral.nih.gov - genomed-dna.com - dx.doi.org - all 6 versions »

The hare and the tortoise: an embryonic haematopoietic race - Full text - MIT Libraries
I Godin, A Cumano - Nat Rev Immunol, 2002 - nature.com
1. Sabin, FR Studies on the origin of blood vessels and of red-blood corpuscles
as seen in the living blastoderm of chicks during the second day of incubation. ...
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Expression profiling of the estrogen responsive genes for evaluation of estrogen activity among …
JT Akaba, H Sone, J Yonemoto, M Tanji, R Kiyama - ehp.niehs.nih.gov
... RCN1, RDH11, RHOC, RIP140, RSK, RUNX1, S100P, SCD, SECTM1, SELENBP1, SERPINA,
SFTPB, SH3BGR, SH3BP5, SHMT2, SLC12A2, SLC1A4, SLC1A5 ...
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LFA-1 co-stimulation inhibits Th2 differentiation by down-modulating IL-4 responsiveness - Full text - MIT Libraries
SA Jenks, BJ Eisfelder, J Miller - International Immunology, 2005 - intimm.oupjournals.org
... In naive T cells, GATA-3 expression and function are held in check by the
transcriptional silencer, Runx1, and by the GATA interacting protein, friend of ...
Web Search - intimm.oupjournals.org - intimm.oupjournals.org - ncbi.nlm.nih.gov

MOLECULAR GENETICS OF T CELL DEVELOPMENT - Full text - MIT Libraries
EV Rothenberg, T Taghon - Annual Review of Immunology, 2005 - arjournals.annualreviews.org
... Other factors, such as c-Myb, PU.1, and Runx1, are required to generate the multipotent
hematopoietic progenitors of T cells, in addition to playing specific ...
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Function and factor interactions of a locus control region element in the mouse T cell receptor- … - Full text - MIT Libraries
BD Ortiz, F Harrow, D Cado, B Santoso, A Winoto - J. Immunol, 2001 - jimmunol.org
... core binding factor (CBF)-TCGACTCCCGCAGAAGCCACATG, ETS1-TCGACCTCTGGAAAGAGGAG,
GATA3-TCGAGTAGAGATAAGATC, E ... include three mammalian proteins: AML-1 (Runx1), AML- ...
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Array-based comparative genomic hybridization for the detection of DNA sequence copy number changes … - Full text - MIT Libraries
B Albrecht, M Hausmann, H Zitzelsberger, H Stein, … - The Journal of Pathology, 2004 - doi.wiley.com
... DBCCR1 TSC1 ABL1 H18962 D9S325 100TEL006 SHGC-44253 D10S249,D10S533 GATA3 WI-2389 ...
ZABC1) CYP24 TNFRSF 6B (DCR3) TPD52L2,TOM 200TEL14 D21S378 RUNX1(AML1) DYRK1A ...
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Development and application of a rat ovarian gene expression database - Full text - MIT Libraries
M Jo, MC Gieske, CE Payne, SE Wheeler-Price, JB … - Endocrinology, 2004 - endo.endojournals.org
Endocrine Society Endocrinology NCI RAPID Program ...
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State-of-the-Art Review on Vascular Stem Cells and Angiogenesis
AJC BLOOR, J SANCHEZ, AR GREEN, B GOeTTGENS - JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH, 2002 - dx.doi.org
Page 1. JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH 11:195–206 (2002) ©
Mary Ann Liebert, Inc. State-of-the-Art Review on Vascular ...
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Parasite-Induced Th2 Polarization Is Associated with Down-Regulated Dendritic Cell Responsiveness to … - Full text - MIT Libraries
D Jankovic, MC Kullberg, P Caspar, A Sher - The Journal of Immunology, 2004 - jimmunol.org
Institution: Google Indexer Sign In as Member or Individual (Non-member). ...
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JBC Papers in Press. Published on October 24, 2001 as Manuscript M107795200
C Kumar-Sinha, S Varambally, A Sreekumar, AM … - jbc.org
Page 1. Molecular Cross-Talk Between the TRAIL and Interferon Signaling Pathways
Chandan Kumar-Sinha, Sooryanarayana Varambally, Arun ...
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Signaling pathways in Th2 development - Full text - MIT Libraries
KA Mowen, LH Glimcher - Immunological Reviews, 2004 - blackwell-synergy.com
Full Article. View/Print PDF article (2698K). Download to reference manager.
Immunological Reviews Volume 202 Issue 1 Page 203 - December ...
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