The cardiac homeobox gene Csx/Nkx2. 5 lies genetically upstream of multiple genes essential for … - Full text - MIT Libraries
CT Basson, W Pease, GM Silberbach, JP Moak, M … - Development, 1999 - dev.biologists.org
... Selective downregulation of N-myc, HAND1 and MEF2C suggested that Csx/Nkx2.5 might
control later differentiation of cardiac myocytes through essential ...
Cited by 102 - Web Search - cardiogenomics.med.harvard.edu - cardiogenomics.med.harvard.edu - ncbi.nlm.nih.gov - all 6 versions »

Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene … - Full text - MIT Libraries
C Biben, R Weber, S Kesteven, E Stanley, L … - Circ Res, 2000 - circresaha.org
... embryos. G through H, Whole-mount in situ hybridization of Nkx2-5 GFP/GFP
and wild-type embryos with MLC2V and Hand1 probes. Avc ...
Cited by 47 - Cached - Web Search - circres.ahajournals.org - ahavj.ahajournals.org - ncbi.nlm.nih.gov - all 8 versions »

Mutations in the cardiac transcription factor NKX2. 5 affect diverse cardiac developmental pathways - Full text - MIT Libraries
DW Benson, GM Silberbach, A Kavanaugh-McHugh, C … - J Clin Invest, 1999 - jci.org
... have identified Nkx2.5 as an upstream regulator and/or transcriptional activator
of other genes expressed during cardiac development including Hand1 (eHand) (9 ...
Cited by 100 - Web Search - jci.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription - Full text - MIT Libraries
RJ Schwartz, EN Olson - Development, 1999 - dev.biologists.org
... The Hand1 bHLH transcription factor is essential for placentation and cardiac ... regulatory
regions in the heart-expressed homeobox gene Nkx2-5. Development 126 ...
Cited by 50 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

The Polycomb-group gene Rae28 sustains Nkx2. 5/Csx expression and is essential for cardiac … - Full text - MIT Libraries
M Shirai, T Osugi, H Koga, Y Kaji, E Takimoto, I … - J Clin Invest, 2002 - jci.org
... Foster City, California, USA) using the previously described oligonucleotide primers
specific for MLC2a, MLC2v, MHC, ANF, Hand1, Nkx2.5, and ß-actin (17, 30-33 ...
Cited by 2 - Web Search - jci.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

Prediction of regulatory SNPs influencing Gene expression on Chromosome 5q31-33
KK Kim, K Kimm - jsbi.org
... tgatATAAAag[t]at Cdx-2 V$NKX25 01 - 1.000/1.0 C[A]CTTga Nkx2-5 246,A V$HAND1E47_01
+ 1.000/0.9 [a]cttgagTCTGGgagt Hand1:E47 IL13 246,G V ...
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Cardiac chamber formation: development, genes and evolution - Full text - MIT Libraries
AFM Moorman, VM Christoffels - Physiol Rev, 2003 - intl-physrev.physiology.org
Institution: Google Indexer Sign In as Member/Non-Member. Physiol. Rev. 83:
1223-1267, 2003; 10.1152/physrev.00006.2003 0031-9333/03 $15.00 ...
Cited by 24 - Web Search - intl-physrev.physiology.org - ncbi.nlm.nih.gov