A genome-wide search for Type II diabetes susceptibility genes in Chinese Hans - Full text - MIT Libraries
TH Luo, Y Zhao, G Li, WT Yuan, JJ Zhao, JL Chen, W … - Diabetologia, 2001 - springerlink.com
... BMIs showed stronger evidence for linkage at D20S196 whereas the rest of the ... 20q
13.3 location contains many candidate genes, among them the HNF4a (MODY1) gene ...
Cited by 36 - Web Search - ncbi.nlm.nih.gov

Genetic Variation Near the Hepatocyte Nuclear Factor-4 Gene Predicts Susceptibility to Type 2 … - Full text - MIT Libraries
K Silander, KL Mohlke, LJ Scott, EC Peck, P … - DIABETES, 2004 - fusion.sph.umich.edu
... 125850) (8). HNF4A has a complex expression pattern, which includes elaborate
alternative splicing (9–11 ... 46 kb upstream of the P1 promoter and the rest of the ...
Cited by 21 - View as HTML - Web Search - diabetes.diabetesjournals.org - intl-diabetes.diabetesjournals.org - ncbi.nlm.nih.gov - all 7 versions »

Liver development update: new embryo models, cell lineage control, and morphogenesis
F Lemaigre, KS Zaret - Curr Opin Genet Dev, 2004 - med.univ-tours.fr
... To address these issues, Young and co-workers performed a genomic location analysis
for HNF1a, HNF4a, and HNF6 [32 ... Strikingly, HNF4a bound to 1575 genes, or12% ...
Cited by 2 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genetics of Common Forms of Glycaemia with Pathological Impact on Vascular Biology: Are We on the …
G Andersen, T Hansen, O Pedersen - Current Molecular Medicine, 2005 - ingentaconnect.com
... whole-genome association mapping with single nucleotide polymorphisms (SNPs) rest
on the ... HNF4A Hepatocyte nuclear factor-4α 20q12-q13.1 [132, 137, 140-149] ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genetic Markers to Predict Polygenic Disease - Full text - MIT Libraries
DJ Galton - Current Science, 1999 - current-reports.com
... Type II diabetes mellitus, 1-7%, INS-R; GLU-t; GK; HNF1a; HNF4a. ... possible; and
protection of the rights of other family members and members of the rest of society ...
Web Search - current-reports.com - biomedcentral.com - ncbi.nlm.nih.gov

Genetic Testing in Clinical Endocrinology
C Polychronakos - HORMONES, 2003 - endocrine-society.gr
... must first be am- plified by PCR to separate it from the 3.5 billion bp of the rest
of the genome ... MODY1 20q12 HNF4a Does not distinguish sub-types Research only ...
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SREBP-1 interacts with HNF-4a and interferes with PGC-1 recruitment to suppress hepatic …
T Yamamoto, H Shimano, Y Nakagawa, T Ide, TM … - jbc.org
... fax+81-29-863-2081 Word Count M&M: 1065, the rest: 2854 words ... bind to HNF4a -RE,
or 2) interferes the recruitment of PGC-1 by HNF-4a. To examine ...
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Hyperinsulinism-Induced Hypoglycaemia: Towards an Understanding of the Molecular Mechanisms of …
KE Cosgrove, RM Shepherd, A Natarajan, KJ Lindley, … - content.karger.com
... cell disorder disorder defect location MODY1 Diabetes 125850 HNF4 HNF4A
20q12–q13.1 Defect in HNF1 expression MODY2Diabetes 12 ...
Web Search - content.karger.com

Perspectives in spicing up proteomics with splicing - Full text - MIT Libraries
J Godovac-Zimmermann, O Kleiner, LR Brown, AK … - PROTEOMICS, 2005 - doi.wiley.com
... recruitment respec- tively, but very little information on the rest of the ... whose
transcription is regulated by hepatocyte nuclear factor 4a (HNF4a) and/or ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Nine novel mutations in maturity-onset diabetes of the young (MODY) candidate genes in 22 Spanish … - Full text - MIT Libraries
R Barrio, C Bellanne-Chantelot, JC Moreno, V Morel … - J Clin Endocrinol Metab, 2002 - jcem.endojournals.org
... patient is well controlled with oral hypoglycemic agents, and the rest are controled ...
Y, Miyagawa J, Fukamizu A, Hanafusa T, Matsuzawa Y 2000 R127W HNF4a is a ...
Cited by 12 - Web Search - jcem.endojournals.org - ncbi.nlm.nih.gov - joplink.net - all 5 versions »

Defining the CREB Regulon: A Genome-Wide Analysis of Transcription Factor Regulatory Regions - Full text - MIT Libraries
S Impey, SR McCorkle, H Cha-Molstad, JM Dwyer, GS … - Cell, 2004 - ohsu.edu
... 1 Cytochrome c oxidase, subunit 4a Cyclin G A K Survival motor neuron Hnf4a p75
NGF R VAMP-associated A Cytochrome P450 20a1 CHK1 Survival motor neuron 1 Sp4 ...
Cited by 6 - View as HTML - Web Search - cmu.edu - neuro.med.harvard.edu - ncbi.nlm.nih.gov

Genetic Association, Post-translational Modification and Protein-protein Interactions in Type 2 …
R Title - mcponline.org
... with the disease qualify, as rare variants while the rest are common variants.
Based on this, we propose that T2DM fits a mosaic model (Fig. ...
Web Search

Multiple QTLs Influencing Triglyceride and HDL and Total Cholesterol Levels Identified in Families …
Y Yu, DF Wyszynski, DM Waterworth, SD Wilton, PJ … - jlr.org
... pressure was measured 3 times after a 5-minute seated rest. ... (HNF4A) regulates the
expression of several hepatic genes including microsomal transfer protein ...
Web Search

Fatty acid-binding proteins–insights from genetic manipulations - Full text - MIT Libraries
NH Haunerland, F Spener - Prog. Lipid Res, 2004 - sfu.ca
... Skeletal muscle cells from these mice at rest showed reduced rates for fatty acid
oxidation and esterification as well as for glucose oxidation. ...
Cited by 6 - View as HTML - Web Search - ncbi.nlm.nih.gov

[BOOK] Diabetes
DJ Betteridge - 1999 - print.google.com
Page 1. DIABETES: CURRENT PERSPECTIVES Th j On e I'll Page 2. DIABETES:
CURRENT PERSPECTIVES Edited by D John Betteridge, BSc PhD ...
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The human obesity gene map: the 2000 update - Full text - MIT Libraries
L Perusse, YC Chagnon, SJ Weisnagel, T Rankinen, E … - Obes Res, 2001 - obesityresearch.org
Page 1. Review The Human Obesity Gene Map: The 2000 Update Louis Pérusse,*
Yvon C. Chagnon,* S. John Weisnagel,* Tuomo Rankinen,† Eric ...
Cited by 51 - Web Search - obesityresearch.org - obesityresearch.org - ncbi.nlm.nih.gov - all 5 versions »

[BOOK] Handbook of Lipoprotein Testing
GR Warnick, MH Dominiczak - 2000 - print.google.com
Page 1. 1 Handbook of Lipoprotein Testing Second Edition Edited by. Nader
Rifal G. Russell Warnick Marek H. Dominiczak AACC Press ...
Cited by 2 - Web Search - Get it from MIT Libraries