Mouse Mutants and Cardiac Development - Full text - MIT Libraries
NMII Cardiogenesis - Circulation Research, 1996 - circresaha.org
... For example, mutations in two transcription factor genes, Hoxa3 and Pax3,
cause pleiotropic effects, including heart anomalies. ...
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Disruption of the Hoxa3 homeobox gene results in anomalies of the carotid artery system and the … - Full text - MIT Libraries
Y Kameda, N Watari-Goshima, T Nishimaki, O Chisaka - Cell Tissue Res, 2003 - springerlink.com
... Deletions of various genes including Pax3 (Franz 1989; Conway et al. ... Hoxa3 homozygous
null mutant mice, produced by gene targeting, show absence of the ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Hoxa3 regulates the proliferation and differentiation of the third pharyngeal arch mesenchyme in … - Full text - MIT Libraries
OCY Kameda - Cell Tissue Res, 2005 - springerlink.com
... In Splotch embryos that lack Pax3, the third, fourth, and sixth pharyngeal arches ...
mutant mice and cardiac neural crest- ablated chicks, the Hoxa3 null mutants ...
Web Search - ncbi.nlm.nih.gov

Evolution of transcription factor function
CC Hsia, W McGinnis - Curr Opin Genet Dev, 2003 - www-biology.ucsd.edu
... Hoxb1 gene partially rescues the function of its Drosophila orthologue, labial
[13], and mouse Pax3 partially rescues the ... [15] tested the mouse Hoxa3 and Hoxd3 ...
Cited by 9 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Thyroid development and its disorders: genetics and molecular mechanisms - Full text - MIT Libraries
M De Felice, R Di Lauro - Endocr Rev, 2004 - edrv.endojournals.org
... in the Pax3 (137) or Endothelin-1 (34) gene show defects in the thyroid similar
to those observed in mice deprived of Hoxa3 or Eya1. Both Pax3 (138) and ...
Cited by 6 - Web Search - edrv.endojournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Generation of a complete thymic microenvironment by MTS 24+ thymic epithelial cells - Full text - MIT Libraries
J Gill, M Malin, GA Hollaender, R Boyd - Nature Immunology, 2002 - nature.com
... Su, DM & Manley, NR Hoxa3 and pax1 transcription factors regulate the ability of ...
Conway, SJ, Henderson, DJ & Copp, AJ Pax3 is required for cardiac neural crest ...
Cited by 42 - Web Search - nature.com - med.monash.edu.au - ncbi.nlm.nih.gov - all 5 versions »

In Search of the Origin of the Thymus: the Thymus and GALT May Be Evolutionarily Related* - Full text - MIT Libraries
T Matsunaga, A Rahman - Scandinavian Journal of Immunology, 2001 - blackwell-synergy.com
... 3, probably with the help of the neural crest cells and of homeotic genes (eg Hoxa3 [
41] and Pax3 [ 42]) which are known to be involved in the thymus ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Table 2. Gene Mutations Demonstrating Cardiac Phenotypes
N Phenotype - ahavj.ahajournals.org
... Has2 (hyaluron synthase 2), Absent AV cushions and trabeculae, 100. Hoxa3
(Hox-1.5/homeobox A3), CT abnormalities, 101. ... Pax3 (paired box gene 3), PTA, CT defects ...
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Neural crest and cardiovascular development: A 20-year perspective
MR Hutson, ML Kirby - Birth Defects Research Part C Embryo Today Reviews, 2003 - doi.wiley.com
... The earli- est knockout was of Hoxa3 and the phenotype was partial in that ... This mouse
has a dys- functional Pax3 gene that leads to cardiac phenotypes similar ...
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1 Characterisation of gene expression in the developing chick heart. By SP ALLEN, PH FRANCIS-WEST*, - Full text - MIT Libraries
NA BROWN, MK RICHARDSON, S ANDERSON, NA BROWN - J. Anat, 1997 - journals.cambridge.org
Page 1. J. Anat. (1997) 191, pp. 123–149 Printed in Great Britain 123 Proceedings
of the Anatomical Society of Great Britain and Ireland ...
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Developing a new paradigm for thymus organogenesis - Full text - MIT Libraries
CC Blackburn, NR Manley - Nature Reviews Immunology, 2004 - nature.com
1. Miller, JFAP Immunological function of the thymus. Lancet 2, 748–749
(1961). | PubMed | ISI | ChemPort |. 2. Anderson, G. & ...
Cited by 8 - Web Search - era.lib.ed.ac.uk - immuneweb.xxmc.edu.cn - ncbi.nlm.nih.gov - all 6 versions »

B ONE D EVELOPMENT - Full text - MIT Libraries
BR Olsen, AM Reginato, W Wang - Annual Review of Cell and Developmental Biology, 2000 - cellbio.annualreviews.org
... al 1998, Rossel & Capecchi 1999), Hoxa2 (Hunt et al 1998), Hoxa3 (Hunt et ... We have
therefore selected (somewhat arbitrarily) one gene, Pax3, as an example, and ...
Cited by 87 - Web Search - astro.annualreviews.org - nutr.annualreviews.org - ncbi.nlm.nih.gov - all 5 versions »

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... of activated T-cells NMYC 01 N-Myc OCT1 02 Octamer factor 1 OCT1 03 Octamer factor
1 OCT1 04 Octamer factor 1 OCT1 Q6 Octamer factor 1 P300 01 p300 PAX3 B Pax3 ...
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Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice - Full text - MIT Libraries
DE Clouthier, K Hosoda, JA Richardson, SC Williams … - Development, 1998 - dev.biologists.org
... Li, 1997), dHAND (Srivastava et al., 1997), HoxA3 (Chisaka and Capecchi, 1991),
NF-1 (Brannan et al., 1994), NT-3 (Donovan et al., 1996) and Pax3 (Conway et al ...
Cited by 195 - Web Search - dev.biologists.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov - all 5 versions »

The Molecular Basis of Vascular Disorders - Full text - MIT Libraries
JA Towbin, B Casey, J Belmont - The American Journal of Human Genetics, 1999 - journals.uchicago.edu
... Mice bearing a mutation for the homeobox transcription factor Hoxa3 have aortic
arch defects reminiscent of DGS, and a subset of Pax3-deficient mice have ...
Cited by 12 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch … - Full text - MIT Libraries
L Feiner, AL Webber, CB Brown, MM Lu, L Jia, P … - Development, 2001 - dev.biologists.org
... Pax3, retinoic acid receptors, and connexin 43 are all expressed in cardiac neural ...
Mice null for HoxA3 or the winged helix transcription factors, Foxc1 (Mf-1 ...
Cited by 52 - Web Search - dev.biologists.org - uphs.upenn.edu - ncbi.nlm.nih.gov

Msx-1 and Msx-2 in Mammary Gland Development
K Satoh, E Ginsburg, BK Vonderhaar - Journal of Mammary Gland Biology and Neoplasia, 2004 - kluweronline.com
... of HoxA3, however, has been shown to lead to cran- iofacial abnormalities (56 ... promoter
contains a conserved binding site for the closely related Pax3 protein (66 ...
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Fate of the mammalian cardiac neural crest - Full text - MIT Libraries
X Jiang, DH Rowitch, P Soriano, AP McMahon, HM … - Development, 2000 - dev.biologists.org
... in these tissues following neural crest ablation in chick embryos (Bockman and Kirby,
1984; Kirby and Waldo, 1990), from mutation of the Pax3 and endothelin 1 ...
Cited by 140 - Web Search - fhcrc.org - fhcrc.org - ncbi.nlm.nih.gov - all 5 versions »

The therapeutic potential of stem cells in the treatment of craniofacial abnormalities
NC Jones, PA Trainor - Expert Opinion on Biological Therapy, 2004 - dx.doi.org
... also been noted to play supporting roles in this process ( Figure 4 ). These include
the glycoprotein, Noelin-1 [41] , transcription factors Pax3 [42] , Foxd3 ...
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Drosophila atonal fully rescues the phenotype of Math1 null mice: new functions evolve in new … - Full text - MIT Libraries
VY Wang, BA Hassan, HJ Bellen, HY Zoghbi - Curr. Biol, 2002 - med.kuleuven.ac.be
... the exception of Hoxa3 and Hoxd3 [26]. ... Multiple protein functions of paired in
Drosophila development and their conservation in the Gooseberry and Pax3 homologs ...
Cited by 9 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

A spectrum of functional genes mobilized after Trichinella spiralis infection in skeletal muscle
Z WU, I NAGANO, T BOONMARS, Y TAKAHASHI - Parasitology, 2005 - journals.cambridge.org
... x 10+ Y07609 max binding protein x 6+ Y11717 homeobox A3 (HOXA3) x 6+ D86603 BTB
and CNC homology 1 (BACH1) x 6+ U45665 Cut-like protein 2 (CUTL2) x 5+ ...
Cited by 1 - Web Search - journals.cambridge.org - journals.cambridge.org

Limb anomalies and craniofacial syndromes II. Gene regulation of morphogenetic and dysmorphogenetic …
FN Synodinos, MJ Papagrigorakis - grortho.gr
Page 1. O P£ O ¢ O N TI K H ET AI PEI A E§ A¢ O ™ 1963
59 ∞ӈ̷ϛ˜ ÙˆÓ ¿ÎÚˆÓ Î·È Û‡Ó‰ÚÔÌ· ÙÔ ...
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[BOOK] Neonatal Cardiology
M Artman, L Mahony, DF Teitel - 2002 - print.google.com
Page 1. Neonatal Cardiology Page 2. NOTICE Medicine is an ever-changing science.
As new research and clinical experience broaden our ...
Cited by 1 - Web Search - Get it from MIT Libraries - Library Search

MOLECULAR INSIGHTS INTO CARDIAC DEVELOPMENT - Full text - MIT Libraries
HM Sucov - Annual Review of Physiology, 1998 - arjournals.annualreviews.org
... Of the numerous mutations available in the Hox genes, only one has a relevant phenotype:
disruption of the HoxA3 gene results in deficient development of the ...
Cited by 29 - Web Search - physiol.annualreviews.org - phyto.annualreviews.org - ncbi.nlm.nih.gov - all 6 versions »

Regulation of Hoxa2 in cranial neural crest cells involves members of the AP-2 family - Full text - MIT Libraries
M Maconochie, R Krishnamurthy, S Nonchev, P Meier, … - Development, 1999 - dev.biologists.org
... in a number of other transcription factors, including AP-2α, Pax3, Pax6 Msx1 ... have
previously used transgenic analysis to scan the Hoxa2-Hoxa3 intergenic region ...
Cited by 48 - Web Search - dev.biologists.org - caradhras.iib.uam.es - ncbi.nlm.nih.gov - all 5 versions »

About face: signals and genes controlling jaw patterning and identity in vertebrates
JM Richman, SH Lee - bone - doi.wiley.com
Page 1. About face: signals and genes controlling jaw patterning and identity
in vertebrates Joy M. Richman 1 * and Sang-Hwy Lee 2 ...
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Autoregulation and multiple enhancers control Math1 expression in the developing nervous system - Full text - MIT Libraries
AW Helms, AL Abney, N Ben-Arie, HY Zoghbi, JE … - Development, 2000 - dev.biologists.org
Page 1. INTRODUCTION The molecular mechanisms underlying development of the
vertebrate nervous system are complex and largely undefined. ...
Cited by 41 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Thymic generation and regeneration - Full text - MIT Libraries
J Gill, M Malin, J Sutherland, D Gray, G Hollander … - Immunological Reviews, 2003 - blackwell-synergy.com
Full Article. View/Print PDF article (10974K). Download to reference manager.
Immunological Reviews Volume 195 Issue 1 Page 28 - October ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A Comparative Study of Head Development in Mexican Axolotl and Australian Lungfish: Cell Migration, …
R ERICSSON - diva-portal.org
Page 1. Comprehensive Summaries of Uppsala Dissertations from the Faculty
of Science and Technology 848 A Comparative Study of Head ...
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Hox Genes and Their Candidate Downstream Targets in the Developing Central Nervous System
ZN Akin, AJ Nazarali - springerlink.com
... function to replace the activity of another member of that same group that has been
disrupted (Horan et al., 1995a,b). As an example, Hoxa3, Hoxb3, and Hoxd3 ...
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