and-independent pathways in A549 cells - Full text - MIT Libraries
YJ Miyazaki, J Hamada, M Tada, K Furuuchi, Y … - Oncogene, 2002 - nature.com
... Yasumasa J Miyazaki 1,2 , Jun-ichi Hamada* ,1 , Mitsuhiro Tada 1 , Keiji Furuuchi ...
the fusion of the nuclear pore complex protein NUP98 and HOXA9 protein, which ...
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Transduction of HOXD3-antisense into human melanoma cells results in decreased invasive and motile …
Y Okubo, J Hamada, Y Takahashi, M Tada, A … - Clin Exp Metastasis, 2002 - springerlink.com
... Correspondence to: Dr Jun-ichi Hamada, Division of Cancer-Related Genes, Institute
for ... fuses the nuclear pore complex protein NUP98 into HOXA9 protein, which ...
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Thrombopoietin induces HOXA9 nuclear transport in immature hematopoietic cells: potential mechanism … - Full text - MIT Libraries
K Kirito, N Fox, K Kaushansky - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... The transcriptome of the leukemogenic homeoprotein HOXA9 in human hematopoietic
cells. ... of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2 ...
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Activation of Stem-Cell Specific Genes by HOXA9 and HOXA10 Homeodomain Proteins in CD34 Human Cord …
CM Ferrell, ST Dorsam, H Ohta, RK Humphries, MK … - stemcells.alphamedpress.org
... roles in multiple signaling pathways, including ß-catenin–TCF, c-Jun-N-terminal ... CD34 +
cells [56], an effect remarkably similar to that of HOXA9 and HOXA10. ...
Web Search - dx.doi.org - stemcells.alphamedpress.org

Jun Dimerization Protein 2: A Multifunctional Transcription Factor in Mammalian Cells
T Yamasaki, M Noguchi, B Liu, K Nakade, PC Wang, T … - Current Genomics, 2005 - ingentaconnect.com
... patients with acute myelogenous leukemia (AML) who express high levels of HoxA9
[41 ... Overexpression of JunB seems to antagonize the c-Jun- mediated induction of ...
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Signaling through CD44 affects cell cycle progression and c-Jun expression in acute myeloid leukemia …
AAP Zada - edoc.ub.uni-muenchen.de
... 51 and JNK expression 4.8 Overexpression of c-Jun overcomes anti-proliferative 51 ...
t(11;22)(q23;p13) MLL /p300 t(7;11)(p15;p15) NUP98/HOXA9 M2 or M4 ...
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hDOT1L links histone methylation to leukemogenesis. - Full text - MIT Libraries
Y Okada, Q Feng, Y Lin, Q Jiang, Y Li, VM Coffield … - Cell, 2005 - ncbi.nlm.nih.gov
... 2005 Jun 3;121(5):809 ... Transformation by MLL-hDOT1L and MLL-AF10 results in upregulation
of a number of leukemia-relevant genes, such as Hoxa9, concomitant with ...
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Rapid Generation of de novo Biological Pathways from Large-Scale Gene Expression Data Using the …
DC Siu - ingenuity.com
... MST4 SH3BP2 FLI1 SYK HDAC6 (In Network 1.Data not shown) MBP MEIS1 HOXA9 PBX1 PBX2 ...
NFkB, MYC, THPO, CEMA, JUN, IGF1, TNF, HGF, OSM, NRG1, EGF, CDH1, KRAS2, IL8 ...
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Antiapoptotic role of the p38 mitogen-activated protein kinase-myocyte enhancer factor 2 … - Full text - MIT Libraries
S Okamoto, D Krainc, K Sherman, SA Lipton - J. Virol, 2004 - dx.doi.org
... T. Camarata, MA Moore, A. Viale, and NR Yaseen The Oncogene Nup98-HOXA9 Induces
Gene ... Hongisto, J. Cao, S. Brecht, T. Herdegen, and MJ Courtney c-Jun N-Terminal ...
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Endothelial Cells Express a Novel, Tumor Necrosis Factor-alpha-regulated Variant of HOXA 9 - Full text - MIT Libraries
CV Patel, R Sharangpani, S Bandyopadhyay, PE … - J Biol Chem, 1999 - jbc.org
... that ubiquitous transcription factors, such as NF- B, ATF-2/c-Jun, and HMG-I ... report
on the characterization of an EC-expressed, novel variant of HOXA9, which is ...
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Progress in Hematology
Y Hayashi - cardenjennings.metapress.com
... from other ALLs, including overexpressed oncogene [HOXA9, MEIS1, HOXA10 ... MAP3K5),
underexpressed proapoptotic genes (ITPR3, IGFBP3, JUN), underexpressed tumor ...
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Complexes of Polyoma Virus Medium T Antigen and Cellular Proteins - Full text - MIT Libraries
T Grussenmeyer, KH Scheidtmann, MA Hutchinson, W … - J. Virol, 2004 - pnas.org
... promotes proliferation by SCF: Potential mechanisms of cooperativity with Hoxa9
in myeloid ... Tschopp, and A. Strasser Fas Ligand-Induced c-Jun Kinase Activation ...
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Thrombopoietin stimulates Hoxb4 expression: an explanation for the favorable effects of TPO on … - Full text - MIT Libraries
K Kirito, N Fox, K Kaushansky - Blood, 2003 - bloodjournal.org
... Each column represents the average Hoxa9 level normalized to GAPDH internal control ±
SD of 2 ... effects of SB203580 on p42/p44 ERK or on c-Jun kinase (JNK) in ...
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A Set of Hox Proteins Interact with the Maf Oncoprotein to Inhibit Its DNA Binding, Transactivation, … - Full text - MIT Libraries
K Kataoka, K Yoshitomo-Nakagawa, S Shioda, M … - J Biol Chem, 2001 - jbc.org
... but clearly distinct DNA binding specificities of Maf and Fos/Jun may explain ... is
especially noteworthy that not only MHox/Pmx1 itself but also HoxA9 and HoxD13 ...
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Vertebral malformations induced by sodium salicylate correlate with shifts in expression domains of …
N Wery, O Foulon, A Blacker, JJ Picard, F Gofflot - Reprod Toxicol, 2005 - ncbi.nlm.nih.gov
2005 May-Jun;20(1):39-45. ... of several Hox genes, selected according to the position
of their anterior limit of expression, namely upstream (Hoxa9), at the level ...
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Regulation of Normal Differentiation in Mouse and Human Myeloid Leukemic Cells by Phorbol Esters and … - Full text - MIT Libraries
J Lotem, L Sachs - Mol. Cell. Biol, 2004 - pnas.org
... Protein Kinase C-Mediated Phosphorylation of the Leukemia-Associated HOXA9 Protein
Impairs ... H. Seimiya, T. Mashima, M. Toho, and T. Tsuruo c-Jun NH2-terminal ...
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Estrogen-regulated Conditional Oncoproteins: Tools to Address Open Questions in Normal Myeloid Cell …
DB Sykes, MP Kamps - Leukemia & Lymphoma, 2003 - dx.doi.org
... proliferation, ultimately, establishing the tyrosine kinase, Ras, Raf, Fos/Jun signal
transduction ... Myb [42], Hoxa9 [27] and E2a-Pbx1 [30,43] are oncoproteins ...
Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Alder J, Cho NK, Hatten ME. Embryonic precursor cells from the rhombic lip are specified to a … - Full text - MIT Libraries
S Alcantara, M Ruiz, F De Castro, E Soriano, C … - Neuron, 1996 - etd.adm.unipi.it
... 2002 Jun 15;246(2):429-40. Chen F, Capecchi MR. Paralogous mouse Hox genes, Hoxa9,
Hoxb9, and Hoxd9, function together to control development of the mammary ...
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Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation … - Full text - MIT Libraries
AC Brun, JM Bjornsson, M Magnusson, N Larsson, P … - Blood, 2004 - bloodjournal.org
... Ter119-depleted fetal liver cells were tested for the expression of Hoxa4, Hoxa9,
Hoxb2, Hoxb3, Hoxb5, Hoxc4, Hoxd4, c-myc, Jun-B, p21, cyclinD1, CXCR4, and c ...
Cited by 8 - Web Search - dx.doi.org - ncbi.nlm.nih.gov - lu-research.lub.lu.se - all 6 versions »

HOX and Non-HOX Homeobox Genes in Leukemic Hematopoiesis - Full text - MIT Libraries
BM Owens, RG Hawley - Stem Cells, 2002 - stemcells.alphamedpress.org
... Interaction of NUP98-HOXA9 with CBP has already been discussed, and is hypothesized
to be ... forms of CREB and other transcription factors, such as c-Jun, c-Fos ...
Cited by 32 - Web Search - stemcells.alphamedpress.org - dx.doi.org - ncbi.nlm.nih.gov

Fusion of the NUP 98 gene with the LEDGF/p 52 gene defines a recurrent acute myeloid leukemia … - Full text - MIT Libraries
D Hussey, S Moore, M Nicola, A Dobrovic - BMC Genetics, 2001 - biomedcentral.com
... AM, Stanton Jr VP, et al.: The t(7;11)(p15;p15) translocation in acute myeloid leukemia
fuses the genes for nucleoporin NUP98 to class I homeoprotein HOXA9. ...
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3.4 Analisi d’expressio de gens apoptotics (V)
S Casas, J Ollila, A Aventin, M Vihinen, J Sierra, … - tdx.cesca.es
... mentre que els factors de transcripció JUN i E2F5 estaven sobreexpressats i NF-ATC1
sotaexpressat. ... proto-oncogenes JUN and GRB10 were up-regulated. ...
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Targeted ubiquitination of CDT 1 by the DDB 1–CUL 4 A–ROC 1 ligase in response to DNA damage - Full text - MIT Libraries
J Hu, CM McCall, T Ohta, Y Xiong - Nature Cell Biology, 2004 - nature.com
... CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein. ...
Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase. ...
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Overexpression of homeobox geneHOXD 3 induces coordinate expression of metastasis-related genes in … - Full text - MIT Libraries
J Hamada, T Omatsu, F Okada, K Furuuchi, Y Okubo, … - International Journal of Cancer, 2001 - doi.wiley.com
... Jun-ichi H AMADA 1 , Tokuhiko O MATSU 1,3 , Futoshi O KADA 2 , Keiji F URUUCHI
1 , Yoshiko O KUBO 1 , Yoko T AKAHASHI 1 , Mitsuhiro T ADA 1 , ...
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Molecular interactions involved in HOXB4-induced activation of HSC self-renewal - Full text - MIT Libraries
N Beslu, J Krosl, M Laurin, N Mayotte, KR … - Blood, 2004 - bloodjournal.org
... cells, 29 but not collaboration between Pbx1b and Hoxb3 or Hoxa9 in induction ... mouse
anti– -tubulin (Sigma, St Louis, MO), and rabbit anti–c-Jun (Santa Cruz ...
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An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation - Full text - MIT Libraries
GW Klappacher, VV Lunyak, DB Sykes, D Sawka- … - Cell, 2002 - rosenfeldlab.ucsd.edu
... Rat 1 cells were also infected with either the control MSCV-GFP retroviral evolved
in Hoxa9 HF-1 cells, a Hoxa9-immortalized pro- Page 3. ...
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Clinical and cytogenetic features of 508 Chinese patients with myelodysplastic syndrome and …
B Chen, WL Zhao, J Jin, YQ Xue, X Cheng, XT Chen, … - Leukemia, 2005 - nature.com
... E, Thorsteinsdottir U, Mayotte N, Nakamura T & Sauvageau G. NUP98-HOXA9 expression
in ... Zhang, Li-Quan Fan for technical assistance, and Yu Liu, Zhao-Jun Wen for ...
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Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional … - Full text - MIT Libraries
TM Williams, ME Williams, JH Heaton, TD Gelehrter, … - Nucleic Acids Research, 2005 - nar.oxfordjournals.org
... Among the interactors, we isolated the BMP-signaling effector Smad5, which interacted
with the paralogous HOXD13 but not with HOXA11 or HOXA9, revealing unique ...
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Chromosomal Translocations in Hematologic Malignancies
CG Brunstein, SJ Dylla, CM Verfaillie - Current Genomics, 2002 - ingentaconnect.com
... 142]. HOXA9 and HOXA10 are highly expressed in early myeloid precursors,
but have low expression in differentiated CD34 - cells. ...
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EFFECTIVE USE OF WEB-BASED PUBLIC GENOMIC DATABANKS FOR AUTOMATIC AND UPDATED PERSONAL ANNOTATIONS …
M Masseroli, A Stella, GE Carrara, M Mazzarani, M … - bioinformatics.polimi.it
... D G protein-coupled receptor 65 GPR65 X D homeo box A9 HOXA9 X X X ... D interleukin
7 receptor IL7R X D v-jun sarcoma virus 17 homolog (avian) oncogene JUN X ...
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The DNA methyltransferase-like protein DNMT 3 L stimulates de novo methylation by Dnmt 3 a - Full text - MIT Libraries
F Chedin, MR Lieber, CL Hsieh - Proceedings of the National Academy of Sciences - pnas.org
... genomic targets (the integrated luciferase gene and the endogenous HOXA9 gene),
we ... Gaudet, F. , Eggan, K. , Humpherys, D. , Mastrangelo, MA , Jun, Z. , Walter ...
Cited by 22 - Web Search - mcb.ucdavis.edu - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

An Overview of Translocation-Related Oncogenesis in the Chronic Myeloid Leukaemias
BJ Bain - Acta Haematologica, 2002 - content.karger.com
... p21 RAS (through GRB/SOS), phosphatidylinositol-3-kinase (PI3K), JUN, MYC and ... This
translocation usually results in formation of a NUP98-HOXA9 fusion gene but ...
Cited by 3 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Importance of replication in microarray gene expression studies: Statistical methods and evidence … - Full text - MIT Libraries
MLT Lee, FC Kuo, GA Whitmore, J Sklar - Plant Physiology, 2004 - dx.doi.org
... U. Vijapurkar, D. Khodabakhsh, B. Pau, H. Bernstein, CM Haqq, C. Largman, and HJ
Lawrence The transcriptome of the leukemogenic homeoprotein HOXA9 in human ...
Cited by 452 - Web Search - pnas.org - cs.cornell.edu - biostat.wisc.edu - all 21 versions »

The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a - Full text - MIT Libraries
S Figures, F Chedin, M Lieber, C Hsieh - Proc Natl Acad Sci US A, 2002 - pubmedcentral.nih.gov
... genomic targets (the integrated luciferase gene and the endogenous HOXA9 gene),
we ... B., Gaudet, F., Eggan, K., Humpherys, D., Mastrangelo, MA, Jun, Z., Walter, J ...
Web Search

Cytogenetic heterogeneity of acute myeloid leukaemia(AML) with trilineage dysplasia: Japan Adult … - Full text - MIT Libraries
Y Miyazaki, K Kuriyama, S Miyawaki, S Ohtake, H … - British Journal of Haematology, 2003 - ingentaconnect.com
... Both of these translocations, generating DEK-CAN and NUP98-HOXA9 fusion genes (von ...
Sumihisa Honda for data analysis, and Takuya Fukushima and Jun Taguchi for ...
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Characterisation of the tumour necrosis factor (TNF)-(alpha) response elements in the human ICAM-2 … - Full text - MIT Libraries
F McLaughlin, VJ Ludbrook, I Kola, CJ Campbell, AM … - J Cell Sci, 1999 - jcs.biologists.org
... enzyme eNOS (MacNaul and Hutchinson, 1993; Rosenkranz-Wiess et al., 1994); the Fas
ligand (Sata and Walsh, 1998); the transcription factor HoxA9 (Patel et al ...
Cited by 12 - Web Search - elib.tiho-hannover.de - jcs.biologists.org - ncbi.nlm.nih.gov

Transcription factor haploinsufficiency: when half a loaf is not enough - Full text - MIT Libraries
JG Seidman, C Seidman - J Clin Invest, 2002 - dx.doi.org
... The mammalian Jun proteins: redundancy and specificity. ... Paralogous mouse Hox genes,
Hoxa9, Hoxb9, and Hoxd9, function together to control development of the ...
Cited by 25 - Web Search - jci.org - pubmedcentral.gov - ncbi.nlm.nih.gov - all 6 versions »

Dokumentation und Evaluation der Weiterbildung Abstracts
O Session - Onkologie, 2002 - content.karger.com
... at the level of the Hox genes themselves (eg NUP98-HOXD13, NUP98-HOXA9, ETV6-CDX2),
at ... and can be mutated in AML) is activated by the co-activator c-Jun, a pro ...
Web Search - content.karger.com

CBP/p300 in cell growth, transformation, and development - Full text - MIT Libraries
RH Goodman, S Smolik - Development, 2000 - genesdev.org
... DNA binding of the fusion protein is mediated by the HOXA9 component and is required
for ... Both components of AP-1, c-jun and c-fos, appear to interact with CBP ...
Cited by 393 - Web Search - genesdev.org - genesdev.org - ncbi.nlm.nih.gov - all 5 versions »

Ethidium Bromide Provides a Simple Tool for Identifying Genuine DNA-Independent Associations - Full text - MIT Libraries
J Lai, W Herr - Proceedings of the National Academy of Sciences - pnas.org
... S. Rozenfeld, A. Kwong, LG Komuves, HJ Lawrence, and C. Largman HOXA9 Forms Triple ...
Residues in the ETS Transcription Factor Erg That Mediate Erg-Jun/Fos-DNA ...
Web Search - adsabs.harvard.edu

TGF-β/BMP signaling in cartilage and bone cells
M Wan, XPD Shi, XPD Cao - Current Opinion in Orthopaedics, 2002 - co-orthopedics.com
... Smad1 and Smad4 have also been shown to interact with HoxA9 [99 ... to immediately and
transiently upregulate mRNA levels of genes (eg, junB and c-jun) coding for AP ...
Web Search - co-orthopedics.com

The MYO1F, unconventional myosin type 1F, gene is fused to MLL in infant acute monocytic leukemia … - Full text - MIT Libraries
T Taki, M Akiyama, S Saito, R Ono, M Taniwaki, Y … - Oncogene, 2005 - nature.com
... gene activity as the MLL-mediated H3 and H4 methylation of the HOXA9 and Hoxc8 ... Chen
AH, Stephan DA, Hasson T, Fukushima K, Nelissen CM, Chen AF, Jun AI, Ramesh ...
Web Search - nature.com - ncbi.nlm.nih.gov

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors - Full text - MIT Libraries
TA Milne, CM Hughes, R Lloyd, Z Yang, O Rozenblatt … - Proceedings of the National Academy of Sciences, 2005 - pnas.org
... targets regulated by menin and MLL were the clustered homeobox genes Hoxa9, c6,
and c8 ... including activator protein-1 (AP-1) family members JunD and c-Jun, NF- B ...
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The granulocytic inducer C/EBP a inactivates the myeloid master regulator PU. 1: possible role in …
AMK und Poliklinik, III am Klinikum Grosshadern - edoc.ub.uni-muenchen.de
... 35 4.4 C/EBPa displaces c-Jun from binding to PU.1 in vitro 36 ... whereas its
down-regulation is necessary for progression of erythropoiesis HOXA9 important role ...
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MONDAY, 7 APRIL 2003
UK Bath - ingentaconnect.com
... of protein kinase B (PKB), signal transducer and activator of transcription 5 (STAT5),
extracel- lular-signal regulated kinases 1/2 (ERK1/2), Jun N-terminal ...
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Expression of Focal Adhesion Kinase in Acute Myeloid Leukemia Is Associated with Enhanced Blast … - Full text - MIT Libraries
F Subscription - Cancer Res, 2004 - amedeo.com
... ML, Will H HIPK2 Regulates Transforming Growth Factor-beta-Induced c-Jun NH(2 ...
Progression of Chronic Myeloid Leukemia and Forms a Fusion Gene with HOXA9 as a ...
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Gene Expression Profiling during All-trans Retinoic Acid-Induced Cell Differentiation of Acute … - Full text - MIT Libraries
L Yang, H Zhao, SW Li, K Ahrens, C Collins, S … - Journal of Molecular Diagnostics, 2003 - jmd.amjpathol.org
... 21 Activa- tion of MAP4K2 resulted in the activation of Jun N-termi- nal kinase
(JNK) and p38 MAP kinase, but not the extra- cellular signal-regulated kinase ...
Cited by 1 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

[PS] CITATIONS FOR PROTEIN/DNA (REGULATORY) - Full text - MIT Libraries
PDA White, X Ding, JC Vanderspek, JR Murphy, D … - J. Biol. Chem, 2004 - aist.go.jp
Page 1. CITATIONS FOR PROTEIN/DNA (REGULATORY) NDB ID Citation 1O4X
DC.Williams, M.Cai, GM.Clore Molecular basis for synergistic ...
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Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth … - Full text - MIT Libraries
R Lu, G Serrero - Proceedings of the National Academy of Sciences, 2001 - pnas.org
... Sussman and Jun Hayashi for critically reading the manuscript and Dr. Jun You for
his ... MA Moore, A. Viale, and NR Yaseen The Oncogene Nup98-HOXA9 Induces Gene ...
Cited by 25 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

[BOOK] Molecular biology of cancer
F Macdonald, CHJ Ford, AG Casson - 2004 - print.google.com
Page 1. r ff 1 Page 2. V 1V L ) TEXT !Bloinformatics C A. Orengo, DT Jones
and JM Thornton (Eds) ISBN: 1 859960545 Published: November ...
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