Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment … - Full text - MIT Libraries
L Roessig, C Urbich, T Bruehl, E Dernbach, C … - J. Cell Biol, 2005 - jem.org
... Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells ...
vascular endothelial growth factor receptor-2 gene requires Sp1-dependent DNA ...
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Upregulated hoxC4 induces CD14 expression during the differentiation of acute promyelocytic leukemia …
DY KIM, SOJ CHOI, S KIM, HEEY CHUNG, S YI - Leukemia & Lymphoma, 2005 - taylorandfrancis.metapress.com
... p-227(m-110,m- 135)CD14luc contains a mutated Sp1 site (GGG at 7 ... HoxA9 and HoxB7
coding sequence were taken from pMSCVflaghoxA9 and pflaghoxB7 and sub- cloned ...
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Rapid Generation of de novo Biological Pathways from Large-Scale Gene Expression Data Using the …
DC Siu - ingenuity.com
... FYN, SYK COL1A2, DNTT,TNC, CDC4, TGFBR2, SP1, SP3, PSG1, ERG, USF1, ETS1 ... PBX1,TR
ALPHA, Malic Enzyme, HOXA9, HOXA11, HOXD12, HOXB13, SST, RB1, E2F1, HOXA10 ...
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The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene … - Full text - MIT Libraries
SJ Erkeland, M Valkhof, C Heijmans-Antonissen, R … - Blood, 2003 - bloodjournal.org
... Figure 3). Therefore, we suggest that the bypass of Sp1 transcriptional control ...
Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes. ...
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Control of biochemical reactions through supramolecular RING domain self-assembly - Full text - MIT Libraries
A Kentsis, RE Gordon, KLB Borden - J. Med. Genet, 2005 - dx.doi.org
... KLB Borden Eukaryotic Translation Initiation Factor 4E Activity Is Modulated by
HOXA9 at Multiple ... Home page A. Hewetson and BS Chilton An Sp1-NF-Y/Progesterone ...
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Functional Cloning and Characterization of a Novel Nonhomeodomain Protein That Inhibits the Binding … - Full text - MIT Libraries
C Abramovich, WF Shen, N Pineault, S Imren, B … - J Biol Chem, 2000 - jbc.org
... PBX1a and HPIP did not shift either oligonucleotide, while HOXA9 and HOXA10 ... domain
reported by Lu and Kamps to selectively repress Sp1-activated transcription ...
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Hox Proteins Activate the IGFBP-1 Promoter and Suppress the Function of hPR in Human Endometrial …
J Gao, J Mazella, L Tseng - DNA and Cell Biology, 2002 - dx.doi.org
... Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control
de- ... hPR modulates the glycodelin promoter activity through the Sp1 sites in ...
Cited by 3 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The Role of C/EBP {varepsilon} in the Terminal Stages of Granulocyte Differentiation - Full text - MIT Libraries
JA Lekstrom-Himes - Stem Cells, 2001 - stemcells.alphamedpress.org
... Sp1 is also essential for CD11b expression [20]. ... HoxA9, HoxA10, and HoxA5 are expressed
early during myelopoiesis, with aberrant expression affecting overall ...
Cited by 19 - Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov - all 5 versions »

Replication Factor Encoded by a Putative Oncogene, set, Associated with Myeloid Leukemogenesis - Full text - MIT Libraries
K Nagata, H Kawase, H Handa, K Yano, M Yamasaki, Y … - Proceedings of the National Academy of Sciences - pnas.org
... Functional Interaction of the DNA-binding Transcription Factor Sp1 through Its ... FG
Repeats That Activate Transcription and Mediate NUP98-HOXA9 Oncogenicity Mol. ...
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S tem C ells - Full text - MIT Libraries
JA Lekstrom-Himes - Stem Cells, 2001 - immuneweb.xxmc.edu.cn
... Sp1 is also essential for CD11b expression [20]. ... HoxA9, HoxA10, and HoxA5 are expressed
early during myelopoiesis, with aberrant expression affecting overall ...
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Characterisation of the tumour necrosis factor (TNF)-(alpha) response elements in the human ICAM-2 … - Full text - MIT Libraries
F McLaughlin, VJ Ludbrook, I Kola, CJ Campbell, AM … - J Cell Sci, 1999 - jcs.biologists.org
... the Fas ligand (Sata and Walsh, 1998); the transcription factor HoxA9 (Patel et ... 1.
Consensus binding sites for transcription factors NF-κB, Sp1, GATA and Ets ...
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Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone- … - Full text - MIT Libraries
AG Uitterlinden, PP Arp, BW Paeper, P Charmley, S … - Am. J. Hum. Genet, 2004 - journals.uchicago.edu
... For example, the COLIA1 Sp1 polymorphism has been found to be associated with BMD ...
a known consensus site; however, it is closely flanked by one HOXA9- and two ...
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Ethidium Bromide Provides a Simple Tool for Identifying Genuine DNA-Independent Associations - Full text - MIT Libraries
J Lai, W Herr - Proceedings of the National Academy of Sciences - pnas.org
... R. Iuliano, E. Chiefari, and A. Brunetti A Nucleoprotein Complex Containing Sp1,
C/EBP{beta ... A. Kwong, LG Komuves, HJ Lawrence, and C. Largman HOXA9 Forms Triple ...
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HOX and Non-HOX Homeobox Genes in Leukemic Hematopoiesis - Full text - MIT Libraries
BM Owens, RG Hawley - Stem Cells, 2002 - stemcells.alphamedpress.org
... in myeloid and B-cell differentiation, expansion of megakaryocyte progenitors, and
ultimately, myeloid leukemia [7]. Mice lacking Hoxa9 have disrupted ...
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Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT … - Full text - MIT Libraries
DE Zhang, P Zhang, ND Wang, CJ Hetherington, GJ … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
Full Text of this Article. PDF Version of this Article. Similar articles found
in: PNAS Online ISI Web of Science PubMed. PubMed Citation. ...
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TGF-β/BMP signaling in cartilage and bone cells
M Wan, XPD Shi, XPD Cao - Current Opinion in Orthopaedics, 2002 - co-orthopedics.com
... directly associate with DNA-binding partners such as FoxH1 (FAST), AP-1, TFE3, Sp1,
Mixer, Runx2 ... Smad1 and Smad4 have also been shown to interact with HoxA9 [99 ...
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The Polycomb Ezh 2 methyltransferase regulates muscle gene expression and skeletal muscle … - Full text - MIT Libraries
G Caretti, M Di Padova, B Micales, GE Lyons, V … - Genes & Development, 2004 - genesdev.org
... The levels of the transcription factor Sp1, used as loading control, did not ...
Interestingly, Suz12 occupies a region of the HoxA9 regulatory regions containing ...
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AC Ward, DM Loeb 2, AA Soede-Bobok, IP Touw and AD Friedman 2
G Factors - Leukemia, 2000 - nature.com
... The ability of C/EBP , but not C/EBP , to cooperate with Sp1 in hepatocytes ... 141 Both
HoxA9 and HoxA10 are highly expressed in human CD34 + cells, but are down ...
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Human Homeobox HOXA 7 Regulates Keratinocyte Transglutaminase Type 1 and Inhibits Differentiation - Full text - MIT Libraries
PT La Celle, RR Polakowska - J Biol Chem, 2001 - jbc.org
... differentiation-specific keratinocyte genes are regulated by the integrated action
of DNA-binding factors, including members of the AP-1, AP-2, Sp1, and ets ...
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Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice - Full text - MIT Libraries
LZ He, C Tribioli, R Rivi, D Peruzzi, PG Pelicci, … - Proc Natl Acad Sci USA, 1997 - dx.doi.org
... Etten, J. Borrow, D. Housman, B. Druker, and DG Gilliland A murine model of CML
blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9 PNAS, May 28 ...
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Histone acetylation and the cell-cycle in cancer
C Wang, M Fu, S Mani, S Wadler, AM Senderowicz, RG … - Front Biosci, 2001 - xylian.igh.cnrs.fr
... of cyclin D1 which is induced by oncogenic signals through Sp1 (90 ... acute myeloid
leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9. ...
Cited by 28 - Cached - Web Search - bioscience.org - bioscience.org - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

The Role of HOX Genes in Human Implantation - Full text - MIT Libraries
H KWON, HS TAYLOR - Ann. NY Acad. Sci, 2004 - annalsnyas.org
... developmental identity more similar to that structure in which HOXA9 is normally ...
Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter ...
Web Search - dx.doi.org - annalsnyas.org

Genomic and proteomic analysis of the myeloid differentiation program. II. Global analysis of gene … - Full text - MIT Libraries
Z Lian, Y Kluger, DS Greenbaum, D Tuck, M Gerstein … - Blood, 2004 - bloodjournal.org
Page 1. Genomic and proteomic analysis of the myeloid differentiation program.
II. Global analysis of gene expression during induced ...
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Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome … - Full text - MIT Libraries
G Chen, W Zeng, A Miyazato, E Billings, JP … - Blood, 2004 - bloodjournal.org
... in both monosomy 7 and trisomy 8 (B94), in monosomy 7 only (TRAIL, HOXA9, BRCA2,
and ... leukemia, only 8 of these genes (EIF-3, EF2, eIF-4, CCNI, H-SP1, PAB1, ORF1 ...
Cited by 4 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov - all 5 versions »

An Efficient and Robust Statistical Modeling Approach to Discover Differentially Expressed Genes … - Full text - MIT Libraries
JG Thomas, JM Olson, SJ Tapscott, LP Zhao - METHODS, 2001 - genome.org
... Furthermore, Set (Li et al. 1996 ) and HoxA9 (Lawrence et al. ... Frequent co-expression
of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias. ...
Cited by 86 - Web Search - sullivan.bu.edu - vision.ime.usp.br - xobi.net - all 10 versions »

Transcription factors, normal myeloid development, and leukemia - Full text - MIT Libraries
DG Tenen, R Hromas, JD Licht, DE Zhang - Blood, 1997 - bloodjournal.org
... 58 Other factors involved in myeloid gene regulation, including Sp1, C/EBP , and
Oct-1, have all been shown to interact with TBP, 59-61 and these interactions ...
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Novel transcription factors in human CD34 antigen-positive hematopoietic cells - Full text - MIT Libraries
I Gomes, TT Sharma, S Edassery, N Fulton, BG Mar, … - Blood, 2002 - bloodjournal.org
Page 1. HEMATOPOIESIS Novel transcription factors in human CD34 antigen–positive
hematopoietic cells Ignatius Gomes, Tiffany T. Sharma ...
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TIF1 functions as a coactivator for C/EBP and is required for induced differentiation in the … - Full text - MIT Libraries
JW Rooney, KL Calame - GENES & DEVELOPMENT - bioscience.drexel.edu
... 2000). Hoxa9, when overexpressed, blocks myeloid dif- ferentiation (Calvo et al ... to
the two intact NF- B-re- sponse elements and the three intact Sp1-response ele ...
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Identification of novel functional regions important for the activity of HOXB7 in mammalian cells - Full text - MIT Libraries
Y Yaron, JK McAdara, M Lynch, E Hughes, JC Gasson - J. Immunol, 2001 - jimmunol.org
... 1997. Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects
in ... kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its ...
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TIF 1 beta functions as a coactivator for C/EBPbeta and is required for induced differentiation in … - Full text - MIT Libraries
JW Rooney, KL Calame - Genes & Development, 2001 - genesdev.org
... Hoxa9, when overexpressed, blocks myeloid differentiation (Calvo et al. ... to the two
intact NF- B-response elements and the three intact Sp1-response elements ...
Cited by 1 - Web Search - genesdev.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Signaling through CD44 affects cell cycle progression and c-Jun expression in acute myeloid leukemia …
AAP Zada - edoc.ub.uni-muenchen.de
... t(11;22)(q23;p13) MLL /p300 t(7;11)(p15;p15) NUP98/HOXA9 M2 or M4 ... binding sites
for several transcription factors, including SP1 (Rozek and ...
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The granulocytic inducer C/EBP a inactivates the myeloid master regulator PU. 1: possible role in …
AMK und Poliklinik, III am Klinikum Grosshadern - edoc.ub.uni-muenchen.de
... whereas its down-regulation is necessary for progression of erythropoiesis HOXA9
important role ... promoter, an octamer site at bp -54, an Sp1 site at bp -39, and ...
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HOXA11 silencing and endogenous HOXA11 antisense ribonucleic acid in the uterine endometrium - Full text - MIT Libraries
YM Chau, S Pando, HS Taylor - The Journal of Clinical Endocrinology & Metabolism - jcem.endojournals.org
... identity resulting in unique adult structures (3, 4). Specifically, Hoxa9 is expressed ...
NJ 1998 Transcriptional interference perturbs the binding of Sp1 to the ...
Cited by 3 - Web Search - jcem.endojournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Polycomb, epigenomes, and control of cell identity - Full text - MIT Libraries
V Orlando - Cell, 2003 - biology.ccsu.edu
... Namely, after determination homolog dTAF II 110 directly contact the SP1 and CREB
of the active state of particular BX-C gene, a transcrip- activation domains. ...
Cited by 75 - View as HTML - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Identification of Homeodomain Proteins, PBX1 and PREP1, Involved in the Transcription of Murine … - Full text - MIT Libraries
SH Chao, JR Walker, SK Chanda, NS Gray, JS … - Mol Cell Biol, 2003 - mcb.asm.org
... 5A). No effects on C1 and C2 complexes were observed in the presence of an unlabeled
nonspecific competitor (ie, SP1 consensus oligonucleotide, Fig. 5A). ...
Cited by 2 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

How to make an egg: transcriptional regulation in oocytes - Full text - MIT Libraries
JL Song, GM Wessel - Differentiation, 2005 - blackwell-synergy.com
... The minimal promoter contains a GC box with putative-binding sites for Sp1 and Sp3
transcription factors and a hormone-responsive element (HRE) (Sylvester and ...
Web Search - ncbi.nlm.nih.gov

The roles of transcription factors in B lymphocyte commitment, development, and transformation
E Smith, M Sigvardsson - Journal of Leukocyte Biology, 2004 - jleukbio.org
... M., Galic, Z., Alva, J., Abrines, R., Yates, Y., Evans, CJ, Aguilera, RJ (2002)
Combinatorial regulation of the murine RAG-2 promoter by Sp1 and distinct ...
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Das Protein DEK im Chromatin menschlicher Zellen
H Hu, PDDH Illges - ub.uni-konstanz.de
Page 1. UNIVERSITÄT KONSTANZ FACHBEREICH BIOLOGIE Das Protein DEK im Chromatin
menschlicher Zellen Dissertation zur Erlangung des akademischen Grades eines ...
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Transcriptional profile analysis of in vivo adult subventricular zone (SVZ) neurogenesis
DA Lim, M Suarez-Farinas, F Naef, C Hacker, B Menn … - asterion.rockefeller.edu
Page 1. Adult SVZ transcriptional profiles Lim et. al., 2004 1 Transcriptional profile
analysis of in vivo adult subventricular zone (SVZ) neurogenesis ...
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Gene Set Enrichment Analysis: A Knowledge-Based Approach for Interpreting Genome-wide Expression …
A Subramanian, P Tamayo, VK Mootha, S Mukherjee, … - stat.duke.edu
Page 1. 8/3/05 1 Gene Set Enrichment Analysis: A Knowledge-Based Approach
for Interpreting Genome-wide Expression Profiles Aravind ...
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Children and adults with acute lymphoblastic leukaemia have similar gene expression profiles. - Full text - MIT Libraries
E Kuchinskaya, M Heyman, D Grander, M Linderholm, … - European Journal Of Haematology, 2005 - blackwell-synergy.com
Page 1. Children and Adults with Acute Lymphoblastic Leukaemia have similar
Gene Expression Profiles E Kuchinskaya 1,6 , M Heyman ...
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EVOLUTION OF COMPONENTS OF GENE REGULATION IN DROSOPHILA AND MAMMALS
ET Dermitzakis - etda.libraries.psu.edu
Page 1. The Pennsylvania State University The Graduate School The Eberly College
of Science EVOLUTION OF COMPONENTS OF GENE REGULATION IN DROSOPHILA AND MAMMALS ...
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Bibliography Current World Literature
H Ashush, LA Rozenszajn, M Blass, M Barda-Saad, D … - Current Opinion in Oncology, 2001 - co-oncology.com
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Bibliography Current world literature
MD Boyano, MD GarciaVazquez, T LopezMichelena, J … - Current Opinion in Hematology, 2001 - co-hematology.com
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Bibliography Current World Literature
CD Bloomfield, KJ Archer, K Mrozek, DM Lillington, … - Current Opinion in Oncology, 2003 - co-oncology.com
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