A novel hsp 110-related gene, apg-1, that is abundantly expressed in the testis responds to a low … - Full text - MIT Libraries
Y Kaneko, H Nishiyama, K Nonoguchi, H Higashitsuji … - J Biol Chem, 1997 - jbc.org
... Nishiyama , Kohsuke Nonoguchi , Hiroaki Higashitsuji , Masamichi Kishishita and
Jun Fujita Dagger ... l of anti-heat shock factor 1 (HSF1) polyclonal antisera ...
Cited by 27 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases … - Full text - MIT Libraries
LJ Yan, ES Christians, L Liu, X Xiao, RS Sohal, IJ … - The EMBO Journal, 2002 - embojournal.npgjournals.com
... Liang-Jun Yan , Elisabeth S. Christians , Li Liu , XianZhong Xiao , Rajindar S.
Sohal 1 ... In this study, using heat shock factor 1 (Hsf1) knockout mice as a model ...
Cited by 25 - Web Search - emboj.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Involvement of c-Jun NH (2)-terminal kinase pathway in differential regulation of heat shock … - Full text - MIT Libraries
SH Kim, D Kim, GS Jung, JH Um, BS Chung, CD Kang - Biochem Biophys Res Commun, 1999 - ingentaconnect.com
... Involvement of c-Jun NH 2 -Terminal Kinase Pathway in Differential Regulation of ...
study, we examined the modulation of heat shock factor 1 (HSF1) activity and ...
Cited by 10 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Exogenous Expression of Heat Shock Protein 90kDa Retards the Cell Cycle and Impairs the Heat Shock … - Full text - MIT Libraries
C Zhao, A Hashiguchi, K Kondoh, W Du, J Hata, T … - Experimental Cell Research, 2002 - ingentaconnect.com
... Unexpectedly, exogenous HSP90 expression impaired the heat shock response by inhibiting
both heat shock transcription factor 1(HSF1) activation and ...
Cited by 3 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Implication of a Small GTPase Rac 1 in the Activation of c-Jun N-terminal Kinase and Heat Shock … - Full text - MIT Libraries
SI Han, SY Oh, SH Woo, KH Kim, JH Kim, HD Kim, HS … - J Biol Chem, 2001 - jbc.org
... Heat shock induces c-Jun N-terminal kinase (JNK) activation as well as heat shock ...
However, Rac1N17 did not prevent phosphorylation of HSF1 in response to these ...
Cited by 12 - Web Search - cellmics.co.kr - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Mouse HSF 1 Disruption Perturbs Redox State and Increases Mitochondrial Oxidative Stress in Kidney
LJ Yan, NS Rajasekaran, S Sathyanarayanan, IJ … - Antioxidants & Redox Signaling, 2005 - ncbi.nlm.nih.gov
Click here to read Mouse HSF1 Disruption Perturbs Redox State and Increases
Mitochondrial Oxidative Stress in Kidney. Yan LJ, Rajasekaran ...
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Activation of multiple transcription factors and fos and jun gene family expression in cells exposed … - Full text - MIT Libraries
T Pazmany, SP Murphy, SO Gollnick, SP Brooks, TB … - Exp Cell Res, 1995 - ncbi.nlm.nih.gov
... the activation of HSF1 DNA binding activity, or the induction of hsp70 or p53 protein
synthesis, indicating that the induction of fos and jun gene expression ...
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Regulated expression of heat shock factor 1 isoforms with distinct leucine zipper arrays via tissue- … - Full text - MIT Libraries
ML Goodson, KD Sarge - Biochem Biophys Res Commun, 1995 - ncbi.nlm.nih.gov
Biochem Biophys Res Commun. 1995 Jun 26;211(3 ... HSF1 mediates the stress induced
expression of heat shock proteins, referred to as the cellular stress response. ...
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Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: … - Full text - MIT Libraries
AB Meriin, JA Yaglom, VL Gabai, L Zon, S Ganiatsas … - Mol Cell Biol, 1999 - mcb.asm.org
... c-Jun activation domain. Cell 76:1025-1037[Medline]. 8. Ding, XZ, GC Tsokos, and
JG Kiiang. 1998. Overexpression of Hsp-70 inhibits the phosphorylation of HSF1 ...
Cited by 81 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

The heat-shock transcription factor HSF1 is rapidly activated by either hyper-or hypo-osmotic stress … - Full text - MIT Libraries
L Caruccio, S Bae, AY Liu, KY Chen - Biochem J, 1997 - biochemj.org
... indicate, respectively, the position of mono-, di- or tri-meric forms of HSF1 on
SDS/PAGE ... expressions of OmpF and proU in bacteria [10,11,38,39], c-jun mRNA [40 ...
Cited by 19 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov

Overexpression of HSP-70 inhibits the phosphorylation of HSF1 by activating protein phosphatase and … - Full text - MIT Libraries
XZ Ding, GC Tsokos, JG Kiang - FASEB J, 1998 - fasebj.org
... by a recent report that indicates a reduction of the stress kinases Jun amino-terminal
kinase and p38 kinase (52). The inhibition of HSF1 phosphorylation by HSP ...
Cited by 33 - Web Search - fasebj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Regulation of HSF1 activation and Hsp expression in mouse tissues under physiological stress … - Full text - MIT Libraries
KD SARGE - Ann. NY Acad. Sci, 1998 - ncbi.nlm.nih.gov
1998 Jun 30;851:112-6. ... Click here to read Regulation of HSF1 activation and Hsp
expression in mouse tissues under physiological stress conditions. Sarge KD. ...
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… depletion inhibits oxidant-induced activation of nuclear factor-kappa B, AP-1, and c-Jun/ATF-2 in … - Full text - MIT Libraries
K Rokutan, S Teshima, M Miyoshi, T Kawai, T Nikawa … - Journal of Gastroenterology, 1998 - springerlink.com
... 5B, c and d, H 2 O 2 at 0.2mM did not increase the levels of c-fos and c-jun mRNAs
in either ... diamide activated HSF1 and induced HSP90, HSP72, HSP60, and HSC73. ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov

Selective Activation of the c-Jun NH 2-terminal Protein Kinase Signaling Pathway by Stimulatory KIR … - Full text - MIT Libraries
MR Snyder, M Lucas, E Vivier, CM Weyand, JJ … - The Journal of Experimental Medicine - intl.jem.org
... Sigma-Aldrich), phospho-ERK1/2 and ERK1/2, phospho-MKK4 and MKK4, or c-Jun,
ATF-2 ... on the membrane are the ERK (egr-1 and c-fos), JNK (ATF-2, hsf1, HSP27, and ...
Cited by 16 - Web Search - dx.doi.org - intl.jem.org - ncbi.nlm.nih.gov

Targeted disruption of hsf1 leads to lack of thermotolerance and defines tissue-specific regulation … - Full text - MIT Libraries
Y Zhang, L Huang, J Zhang, D Moskophidis, NF … - J Cell Biochem, 2002 - doi.wiley.com
... Targeted Disruption of hsf1 Leads to Lack of ... Regulation of Hsps by Hsf1 is highly
complex and, in the whole organism, remains largely unexplored. ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov

TNFa mediates susceptibility to heat-induced apoptosis by protein phosphatase-mediated inhibition of … - Full text - MIT Libraries
G Schett, CW Steiner, Q Xu, JS Smolen, G Steiner - Cell Death and Differentiation, 2003 - nature.com
... as well as the caspase cascade did not prevent downregulation of HSF1/hsp70. ... kinase;
HSF, heat shock factor; hsp, heat shock protein; JNK, C-jun N-terminal ...
Cited by 4 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A non-toxic heat shock protein 70 inducer, geranylgeranylacetone, suppresses apoptosis of cultured …
S Ikeyama, K Kusumoto, H Miyake, K Rokutan, S … - Journal of Hepatology, 2001 - ingentaconnect.com
... for 2 h enhanced nuclear translocation and phosphorylation of HSF1, HSF1-DNA binding ...
response, GGA suppressed the insult-induced activation of c-Jun N-terminal ...
Cited by 15 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Heat shock factor 1-deficient mice exhibit decreased recovery of hearing following noise … - Full text - MIT Libraries
DA Fairfield, MI Lomax, GA Dootz, S Chen, AT … - J Neurosci Res, 2005 - ncbi.nlm.nih.gov
J Neurosci Res. 2005 Jun 10; [Epub ahead of print ... Heat shock factor 1 (Hsf1) is the
major transcription factor that regulates stress-inducible Hsp expression. ...
Web Search

GEArray Q Series Human Signal Transduction PathwayFinder Gene Array: AR-SAHS-008
FG Grouping, H Pathway, BMP BMP, S Pathway, S … - eurogentec.com
... AKT Pathway: BCL2, CCND1 (cyclin D1), FN1 (fibronectin), JUN (c-jun), MMP-7 ... Stress
Pathway: ATF2, FOS (c-fos), HSF1 (tcf5), HSPB1 (hsp27), HSPCA (hsp90), MYC (c ...
View as HTML - Web Search - eurogentec.be

GEArray Q Series Mouse Signal Transduction PathwayFinder Gene Array: AR-SAMM-008
FG Grouping, H Pathway, B Bmp, S Pathway, S … - eurogentec.com
... AKT Pathway: Bcl2, Ccnd1 (cyclin D1), Fn1 (fibronectin), Jun (c-jun), Myc (c-myc ...
Stress Pathway: Atf2, Fos (c-fos), Hsf1 (tcf5), Hsp25 (hsp27), Hsp90, Myc (c-myc ...
View as HTML - Web Search - eurogentec.be

Heat shock response, heat shock transcription factor and cell aging
YK Lee, D Manalo, AY Liu - Biol Signals, 1996 - ncbi.nlm.nih.gov
1996 May-Jun;5(3):180-91. ... Analyses of the regulation and function of heat shock factor
1 (HSF1), a transcription factor that mediates the response to heat shock ...
Cited by 21 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Protein phosphatase 5 is a negative modulator of heat shock factor 1. - Full text - MIT Libraries
R Conde, J Xavier, C McLoughlin, M Chinkers, NC … - J Biol Chem, 2005 - ncbi.nlm.nih.gov
2005 Jun 20; [Epub ahead of print ... The major stress protein transcription factor,
heat shock factor (HSF1) is tightly regulated through a multi-layered activation ...
Web Search

ORN-014 (previously ORN-004)
FG Grouping, H Pathway, B Bmp, S Pathway, S … - search.cosmobio.co.jp
... PI3 Kinase / AKT Pathway: Bcl2, Ccnd1, Fn1 (fibronectin), Jun (c-jun), Myc (c ... Stress
Pathway: Atf2, c-fos (Fos), Hsf1 (tcf5), Hsp90-M, Hspb1 (hsp25), Hspca, Myc ...
View as HTML - Web Search

GEArray Q Series Mouse Signal Transduction in Cancer Gene Array: AR-SAMM-044
FG Grouping, A Pathway, C Cdk, E Pathway, B Bcl, H … - eurogentec.be
... 16 (4): 455-62 3. Ianaro A, Ialenti A, Maffia P, Pisano B, Di Rosa M. HSF1/hsp72
pathway as an endogenous anti-inflammatory system. FEBS Lett. 2001 Jun 22; 499 ...
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… STRESS-ACTIVATED PROTEIN KINASES, EXTRACELLULAR SIGNAL–REGULATED KINASE, c-JUN N-TERMINAL KINASE, … - Full text - MIT Libraries
CINR ARTHRITIS - ARTHRITIS & RHEUMATISM, 2000 - doi.wiley.com
... kinase (p38 MAPK), extracellular signal–regulated kinase (ERK), and c-Jun N-terminal ...
shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in ...
Web Search - doi.wiley.com

GEArray Q Series Human Signal Transduction in Cancer Gene Array: AR-SAHS-044
FG Grouping, A Pathway, C CDK, E Pathway, B BCL, H … - eurogentec.com
... 16 (4): 455-62 3. Ianaro A, Ialenti A, Maffia P, Pisano B, Di Rosa M. HSF1/hsp72
pathway as an endogenous anti-inflammatory system. FEBS Lett. 2001 Jun 22; 499 ...
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[BOOK] Regulation of heat shock factor 1 (HSF1) DNA-binding and transcription
PA Mercier - 2004 - library.usask.ca
Page 1. Regulation of Heat Shock Factor 1 (HSF1) DNA-binding ... ii Abstract Cellular
stress invokes a protective response in which heat shock factor 1 (HSF1) ...
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Combined effect of high temperrature and nicotine on HSPs genes expression and their regulation
PT Tang, ZX Zhaung, HZ He, GG Zhang - Toxicology Letters, 1998 - ingentaconnect.com
... The HSF1 transcription activation was affected by its phosphorylated, heat-induced
phosphorylation related to PKC activity. Fos (and) or Jun and TNFa related ...
Web Search - ingentaconnect.com

Nitric Oxide Induces Heat-shock Protein 70 Expression in Vascular Smooth Muscle Cells Via Activation … - Full text - MIT Libraries
Q Xu, Y Hu, R Kleindienst, G Wick - Nitric Oxide, 1997 - jci.org
... involved. We examined the composition of the DNA-binding complexes using
antibodies to HSF1, HSF2, c-Jun, and ATF2. Addition of ...
Cited by 55 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 4 versions »

Interference of Apoptosis and Heat Shock Response Gene Networks
IL Stepanenko - Stress - kluweronline.com
... c-Jun phosphorylation, enhances expression of the c-fos and c-jun mRNAs, and ... severe
heat shock; JNK phospho- rylates the regulatory domain of HSF1 and thereby ...
Web Search - springerlink.com - wwwmgs.bionet.nsc.ru

Characterization of constitutive HSF2 DNA-binding activity in mouse embryonal carcinoma cells - Full text - MIT Libraries
SP Murphy, JJ Gorzowski, KD Sarge, B Phillips - Mol. Cell. Biol, 1994 - pubmedcentral.nih.gov
... genes is accompanied by oligomerization, modification, and rapid translocation of
heat shock transcription factor HSF1. ... Mol Cell Biol 1989 Jun;9(6):2615–2626 ...
Cited by 32 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Binding of heat shock factor to and transcriptional activation of heat shock genes in Drosophila - Full text - MIT Libraries
M Fernandes, H Xiao, JT Lis - Nucleic Acids Res, 1995 - pubmedcentral.nih.gov
... Cooperative interaction of human HSF1 heat shock transcription factor
with promoter DNA. ... Mol Cell Biol 1993 Jun;13(6):3456–3463. ...
Cited by 13 - Web Search - nar.oupjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The carboxyl-terminal transactivation domain of heat shock factor 1 is negatively regulated and … - Full text - MIT Libraries
Y Shi, PE Kroeger, RI Morimoto - Mol. Cell. Biol, 1995 - mcb.asm.org
... of HSF1, whereas the Fos activator is com- posed of two regions (1). As has been
shown for HSF1, the Fos and Jun activation domains are negatively regulated. ...
Cited by 58 - Web Search - biochem.northwestern.edu - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Cell-specific expression of heat shock transcription factors 1 and 2 in unstressed rat spinal cord - Full text - MIT Libraries
A Stacchiotti, R Rezzani, L Rodella, L Tiberio, L … - Neurosci. Lett, 1999 - ncbi.nlm.nih.gov
1999 Jun 18;268(2):73-6 ... We investigated the intracellular distribution of heat shock
factors 1 and 2 (HSF1, HSF2) in rat spinal cord by immunoblotting and ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

Stressing Rac, Ras, and downstream heat shock protein 70 - Full text - MIT Libraries
KE Bornfeldt - Circ Res, 2000 - circresaha.org
... Xu et al additionally show that although ERK, c-Jun NH 2 -terminal protein kinase ...
of ERK or p38 MAPK using chemical inhibitors does not block HSF1-DNA binding. ...
Cited by 7 - Cached - Web Search - circres.ahajournals.org - intl-circres.ahajournals.org - ncbi.nlm.nih.gov - all 5 versions »

BIOINFORMATICS ORIGINAL PAPER
P Hong, XS Liu, Q Zhou, X Lu, JS Liu, WH Wong - fas.harvard.edu
... A boosting approach for motif modeling using ChIP-chip data Pengyu Hong 1 , X. Shirley
Liu 2 , Qing Zhou 1 , Xin Lu 2 , Jun S. Liu 1,2 and Wing H. Wong 1,2,∗ ...
View as HTML - Web Search - serine.umdnj.edu

Protein synthesis is required for stabilization of hsp70 mRNA upon exposure to both hydrostatic … - Full text - MIT Libraries
K Kaarniranta, CI Holmberg, HJ Helminen, JE … - FEBS Lett, 2000 - ncbi.nlm.nih.gov
2000 Jun 23;475(3):283-6 ... accumulated in HeLa, HaCat and MG-63 cells under 30 MPa
HP, without DNA-binding of heat shock transcription factor 1 (HSF1) to the heat ...
Cited by 11 - Web Search

Inhibition of heat shock transcription factor by GR - Full text - MIT Libraries
SA Wadekar, D Li, S Periyasamy, ER Sanchez - Mol Endocrinol, 2001 - mend.endojournals.org
... Because more recent reports (32, 33, 34) have also demonstrated a similar inhibition
of HSF1 by c-jun N-terminal kinase (JNK), we also tested the effects of in ...
Cited by 12 - Web Search - mco.edu - subhagya.wadekar.tripod.com - ncbi.nlm.nih.gov - all 5 versions »

Stressing Rac, Ras, and Downstream Heat Shock Protein 70 - Full text - MIT Libraries
MFI hsp70 Expression, IACS Stress - Circ Res, 2000 - cmbi.bjmu.edu.cn
... Xu et al additionally show that although ERK, c-Jun NH 2 -terminal protein kinase ...
of ERK or p38 MAPK using chemical inhibitors does not block HSF1-DNA binding. ...
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SB202190-and SB203580-Sensitive p38 Mitogen-Activated Protein Kinase Positively Regulates Heat Shock …
SH Kim, SI Han, SY Oh, MS Seo, HG Park, HS Kang - J. Biomed. Lab. Sci, 2003 - biomed.or.kr
... Under unstressed conditions, the HSF1 activity is repressed through its constitutive ...
kinase 1/2 (ERK1/2), and stress- activated protein kinase/c-Jun N-terminal ...
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Fine structure analyses of the Drosophila and Saccharomyces heat shock factor-heat shock element … - Full text - MIT Libraries
M Fernandes, H Xiao, JT Lis - Nucleic Acids Res, 1994 - pubmedcentral.nih.gov
... Mol Cell Biol 1993 Jun;13(6):3370–3383. ... [PubMed]; Rabindran SK, Giorgi G, Clos J,
Wu C. Molecular cloning and expression of a human heat shock factor, HSF1. ...
Cited by 41 - Web Search - nar.oupjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Effects of Lactated Ringer's Solutions on Human Leukocytes.
EPD Koustova, K Stanton, V Gushchin, HB Alam, S … - The Journal of Trauma: Injury, Infection, and Critical Care, 2002 - jtrauma.com
... Among the genes chosen for analysis were the genes associated with the stress response
and apoptosis (c-jun, heat shock factor protein [hsf1], heat shock ...
Cited by 17 - Web Search - jtrauma.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Heat Shock Transcription Factor 1 Protects Cardiomyocytes From Ischemia/Reperfusion Injury - Full text - MIT Libraries
Y Zou, W Zhu, M Sakamoto, Y Qin, H Akazawa, H Toko … - Circulation, 2003 - circ.ahajournals.org
... Conclusions— These results suggest that HSF1 protects cardiomyocytes from death
at least in part through activation of Akt and inactivation of Jun N-terminal ...
Cited by 4 - Web Search - ahavj.ahajournals.org - circ.ahajournals.org - ncbi.nlm.nih.gov - all 5 versions »

Redox-dependent changes in structure and function of hHSF1
Z Lin, F Huang, ZF Ma, K Xu, AY Liu - Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai), 2003 - ncbi.nlm.nih.gov
2003 Jun;35(6):542-7 ... a compact, intramolecularly disulfide-crosslinked, stable monomeric
form of ox-hHSF1, and blocked the trimerization and activation of HSF1. ...
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Post-translational modification by the small ubiquitin-related modifier SUMO has big effects on …
G Gill - Curr. Opin. Genet. Dev, 2003 - genetics.biol.ttu.edu
... factors is also regulated by SUMO-modification including Sp3, HSF1, and TEL ...
overexpression of the SUMO protease SuPr-1 stimulated c-jun dependent transcription ...
Cited by 32 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

REB1, a yeast DNA-binding protein with many targets, is essential for growth and bears some … - Full text - MIT Libraries
QD Ju, BE Morrow, JR Warner - Mol. Cell. Biol, 1990 - pubmedcentral.nih.gov
... common to many of the general DNA-binding proteins of Saccharomyces cerevisiae,
such as ABF1, RAP1, GCN4, and HSF1. ... Mol Cell Biol 1986 Jun;6(6):2089–2097. ...
Cited by 34 - Web Search - ncbi.nlm.nih.gov

Small Molecule Activators of the Heat Shock Response and Neuroprotection from Stroke - Full text - MIT Libraries
DB DeFranco, L Ho, MP BMed, E Falke, CW Callaway - Current Science, 2004 - current-reports.com
... with select proteins in their native conformation [8]. For example, antiapoptotic
effects of Hsp70 can be mediated via its inhibition of c-Jun N-terminal ...
Web Search - current-reports.com - biomedcentral.com - ncbi.nlm.nih.gov

Regulation of Heat Shock Transcription Factor 1 by Stress-induced SUMO-1 Modification - Full text - MIT Libraries
Y Hong, R Rogers, MJ Matunis, CN Mayhew, M Goodson … - J Biol Chem, 2001 - jbc.org
... of a number of important transcription factors, including p53, c-Jun, and androgen
receptor ... clearly plays a role in regulating the function of HSF1 during the ...
Cited by 50 - Web Search - jbc.org - ncbi.nlm.nih.gov

Heat Shock Factor 1 Represses Ras-induced Transcriptional Activation of the c-fos Gene - Full text - MIT Libraries
C Chen, Y Xie, MA Stevenson, PE Auron, SK … - J Biol Chem, 1997 - jbc.org
... of ILIB during fever (8). We are interested to know whether HSF1 affects other ...
c-fos encodes the nuclear Fos protein, which associates with Jun proteins to ...
Cited by 20 - Web Search - jbc.org - ncbi.nlm.nih.gov

Regulation and Function of SUMO Modification - Full text - MIT Libraries
RS Hilgarth, LA Murphy, HS Skaggs, DC Wilkerson, H … - J Biol Chem, 2004 - jbc.org
... including c-Jun, promyelocytic leukemia (PML), and I B , (2, 3). Phosphorylation
can also act positively, as in the case of the transcription factor HSF1 where ...
Cited by 8 - Web Search - jbc.org - ncbi.nlm.nih.gov