SHORT REPORT REDUCED EXPRESSION OF MYO18B, A CANDIDATE TUMOR-SUPPRESSOR GENE ON CHROMOSOME ARM 22Q, … - Full text - MIT Libraries
N Yanaihara, M Nishioka, T Kohno, A Otsuka, A … - Int. J. Cancer, 2004 - doi.wiley.com
... and Jun Y OKOTA 1 * 1 Biology Division, National Cancer Center Research Institute ...
This chromosome arm contains 3 known TSGs, NF2, EP300 and SNF5/INI1, which are ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

MYO 18 B, a candidate tumor suppressor gene at chromosome 22 q 12. 1, deleted, mutated, and … - Full text - MIT Libraries
M Nishioka, T Kohno, M Tani, N Yanaihara, Y … - Proceedings of the National Academy of Sciences - pnas.org
... Arafumi Maeshima * , Yoshitaka Sekido , John D. Minna § , Saburo Sone , and Jun
Yokota ... Three known TSGs, SNF5/INI1, NF2, and EP300, have been mapped to 22q11.2 ...
Cited by 15 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Mutations and Deletions of the CBP Gene in Human Lung Cancer - Full text - MIT Libraries
M Kishimoto, T Kohno, K Okudela, A Otsuka, H … - Clinical Cancer Research, 2005 - clincancerres.aacrjournals.org
... Requests for reprints: Jun Yokota, Biology Division, National Cancer Center Research
Institute ... Importantly, as for the EP300 gene, which also encodes a histone ...
Web Search - clincancerres.aacrjournals.org - ncbi.nlm.nih.gov

Oligo GEArray® Human HIV Infection & Host Response Microarray
S Conditions - search.cosmobio.co.jp
... HTATIP2, LTBR, PTK2B Cell cycle regulators: CCNT1, CDK7, CDK9, EP300, RBL2, SMARCB1 ...
factors and regulators: CDK9, CEBPB, FOS, IRF1, IRF2, JUN, NFATC1, NFIB ...
View as HTML - Web Search

TP 73 allelic expression in human brain and allele frequencies in Alzheimer's disease - Full text - MIT Libraries
Q Li, E Athan, M Wei, E Yuan, S Rice, JP Vonsattel … - BMC Medical Genetics, 2004 - w02.biomedcentral.com
... Zhao, Peng-Yuan Liu, Yan Lu, Volodymyr Dvornyk, Hui Shen, Yong-Jun Liu, Yuan ... article
No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 ...
Cited by 1 - Cached - Web Search - dx.doi.org - molecular-cancer.com - doaj.org - all 11 versions »

GEArray Q Series Human Wnt Signaling Pathway Gene Array: AR-SAHS-043
FG Grouping, R Ligand, R Molecules, I Molecules - eurogentec.com
... Target genes: Canonical (Wnt / beta-catenin) Pathway: Transcription factors: CDX1,
EP300, FOSL1 (Fra-1), ID2, ID3, JUN, MSX1, MSX2, MYC, PITX2, T (Brachyury ...
View as HTML - Web Search - eurogentec.be

Ingenuity Pathways Analysis Identifies Molecular Network Shift with Progression to Metastatic …
P Stratification - ingenuity.com
... Application Note 0704 Page 6 c-Jun and Fos positively affect proliferation, JunB
and JunD are anti-oncogenic. ... Application Note 0704 Page 8 EP300 ...
View as HTML - Web Search

GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... EGR2, EGR3, ELK1, ELK3, ELK4, EP300, ETS1, ETS2, FKBP1B, FLJ14639 (NIP45), FOS,
FOSL1, FOXO1A, FOXO3A, GATA3, GATA4, GRLF1, ICOS, IRF1, ISGF3G, JUN, JUNB, MADH4 ...
View as HTML - Web Search - eurogentec.be

Genetic and epigenetic alterations of the candidate tumor-suppressor geneMYO 18 B, on chromosome arm …
T Nakano, M Tani, M Nishioka, T Kohno, A Otsuka, S … - Genes Chromosomes and Cancer, 2005 - doi.wiley.com
... chromosome arm contains three known TSGs that are inactivated in several types of
human cancers: NF2, EP300, and SNF5 ... Correspondence to: Dr. Jun Yokota, Biology ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Towards an understanding of complex protein networks - Full text - MIT Libraries
CL Tucker, JF Gera, P Uetz - Trends Cell Biol, 2001 - csb.yale.edu
Page 1. Large-scale two-hybrid screens have generated a wealth of information
describing potential protein–protein interactions. ...
Cited by 72 - View as HTML - Web Search - chagall.med.cornell.edu - biology.duke.edu - igtmv1.fzk.de - all 9 versions »

GEArray Q series Human Ca2+/NF-AT Signaling Pathway Gene Array: AR-SAHS-022
FG Grouping, RT Factors, C CEBPB, NA Receptors, … - eurogentec.be
... Related Transcription Factors: CEBPB, CREBBP, EGR2, EGR3, EP300, FKBP1B, FLJ14639
(NIP45), FOS, FOSL1, GATA3, GATA4, GRLF1, ICOS, JUNB (Jun-B), MEF2A, MEF2B ...
View as HTML - Web Search - eurogentec.com

GEArray S Series Human Autoimmune and Inflammatory Response Gene Array: AR-SAHS-602
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.be
... CEBPB, CREB1, CREBBP, EGR1, EGR2, EGR3, ELK1, ELK3, EP300, FKBP1B, FLJ14639 (NIP45),
FOS, FOSL1, FOSL2, FOXP3, GATA3, GATA4, GRLF1, ICOS, IRF1, JUN, JUNB, JUND ...
View as HTML - Web Search - eurogentec.com

p 53 down-regulates matrix metalloproteinase-1 by targeting the communications between AP-1 and the … - Full text - MIT Libraries
Y Sun, XR Zeng, L Wenger, GS Firestein, HS Cheung - Journal of Cellular Biochemistry, 2004 - doi.wiley.com
... Madison,WI). The pFR-luci and fusion transactivator plas- mids pFA2-c-jun,
pFA2-Elk1, and pFA2-CHOP were obtained from Stratagene. The ...
Cited by 1 - Web Search - peo.cshl.org - ncbi.nlm.nih.gov

The role of emerging genomics and proteomics technologies in cancer drug target discovery.
P Onyango - Current Cancer Drug Targets, 2004 - ingentaconnect.com
... EP300 E1A-binding protein (p300) gene Colorectal; breast and pancreatic cancers
22q13.2 ... JUN Homolog of v-jun avian sarcoma virus 17 oncogene ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Emerging issues in genotoxicology
BJ Barclay - currentdrugdiscovery.com
... hydrolase organelles EP300 Histone acetyltransferase Regulation of transcription
Colorectal, breast ... JUN Leucine zipper protein Transcription factor Lung ...
View as HTML - Web Search - inpharm.com

Acetyltransferases and tumour suppression - Full text - MIT Libraries
AC Phillips, KH Vousden - Breast Cancer Res, 2000 - biomedcentral.com
... play important roles in the regulation of cell growth, such as c-jun, E2F-1 ... Gayther
SA, Batley SJ, Linger L, et al.: Mutations truncating the EP300 acetylase in ...
Cited by 8 - Web Search - dx.doi.org - pubmedcentral.nih.gov - breast-cancer-research.com - all 11 versions »

HISTONE-DEACETYLASE INHIBITORS: NOVEL DRUGS FOR THE TREATMENT OF CANCER - Full text - MIT Libraries
RW Johnstone - Nature Reviews Drug Discovery, 2002 - nature.com
... | Article | PubMed | ISI | ChemPort |. 22. Gayther, SA et al. Mutations truncating
the EP300 acetylase in human cancers. Nature Genet. 24, 300-303 (2000). ...
Cited by 137 - Web Search - nature.com - ncbi.nlm.nih.gov

BMC Blood Disorders - Full text - MIT Libraries
Q Waisfisz, A Miyazato, JP de Winter, JM Liu, H … - BMC Blood Disorders, 2002 - biomedcentral.com
... Some of these genes respond within hours after treatment of cells, eg c-jun, whereas
others show maximum changes in ... E1A binding protein p300, EP300 U01877 2 ...
View as HTML - Web Search - bmc.ub.uni-potsdam.de - gdrs-intranet.ath.cx

HISTONE DEACETYLASES AND CANCER: CAUSES AND THERAPIES - Full text - MIT Libraries
PA Marks, RA Rifkind, VM Richon, R Breslow, T … - Nature Reviews Cancer, 2001 - nature.com
... | Article | PubMed | ISI | ChemPort |. 49. Gayther, SA et al. Mutations truncating
the EP300 acetylase in human cancers. Nature Genet. 24, 300-303 (2000). ...
Cited by 196 - Web Search - nature.com - ncbi.nlm.nih.gov

High-resolution gene copy number and expression profiling of human chromosome 22 in ovarian …
M Benetkiewicz, Y Wang, M Schaner, P Wang, KK … - Genes Chromosomes and Cancer, 2005 - doi.wiley.com
... These genes are: RBX1, EP300, TCF20, and NUP50. The EP300 gene is considered
a tumor suppressor that encodes the interacting protein ...
Cited by 3 - Web Search - puffer.genpat.uu.se - ncbi.nlm.nih.gov - Get it from MIT Libraries

Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the …
C Aston, L Jiang, BP Sokolov - Molecular Psychiatry, 2005 - nature.com
... other GO terms (Table 4). Within the neurogenesis GO term, there were several genes
related to myelination (MOG, MOBP, PMP22, PLP1, KLK6, EP300) and axonal ...
Cited by 4 - Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase ( … - Full text - MIT Libraries
XJ WANG, M CHAMBERLAIN, O VASSIEVA, CJ HENDERSON, … - Biochem. J, 2005 - biochemj.org
... in the cytochrome P450 reductase (POR) null mice Xiu Jun Wang†, Mark Chamberlain†,
Olga Vassieva‡, Colin J. Henderson†, and C. ... mRNAs encoding Jun, ...
View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Epigenetic transitions: towards therapeutic targets
T Kalebic - Expert Opinion on Therapeutic Targets, 2003 - dx.doi.org
... Mutations truncating the EP300 have been detected in a vari- ety of tumours ... E, Bcl
(B cell chronic lymphoblastic leukaemia/lymphoma)-2/Bcl-x, c-Jun/AP1, caspase ...
Web Search - extenza-eps.com - ashley-pub.com - ingentaconnect.com - all 10 versions »

Identification and validation of novelERBB 2(HER 2, NEU) targets including genes involved in … - Full text - MIT Libraries
J Beckers, F Herrmann, S Rieger, AL Drobyshev, M … - International Journal of Cancer, 2005 - doi.wiley.com
... Some of these genes, such as Her2 (neu/Erbb2), T2, Myc, Ep300 (P300), Fra-2 (Fosl2),
c-fos (Fos) and JunD (Jund1 ... Jun is represented by 2 probes on the DNA chip ...
Cited by 2 - Web Search

ORIGINAL ARTICLE CBP sensitizes v-myb-transformed monoblasts to differentiation inducers - Full text - MIT Libraries
S Jana, A Nemajerova, J Navratilova, P Jurdic, S … - Differentiation, 2005 - blackwell-synergy.com
... T. (1995) Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 ... BA, Kouzarides,
T. and Caldas, C. (2000) Mutations truncating the EP300 acetylase in ...
Web Search - ingentaconnect.com

CBP/p300 in cell growth, transformation, and development - Full text - MIT Libraries
RH Goodman, S Smolik - Development, 2000 - genesdev.org
... 1994 ). Both components of AP-1, c-jun and c-fos, appear to interact with CBP/p300,
but the mechanisms underlying these interactions remain poorly defined. ...
Cited by 393 - Web Search - genesdev.org - genesdev.org - ncbi.nlm.nih.gov - all 5 versions »

[BOOK] Molecular biology of cancer
F Macdonald, CHJ Ford, AG Casson - 2004 - print.google.com
Page 1. r ff 1 Page 2. V 1V L ) TEXT !Bloinformatics C A. Orengo, DT Jones
and JM Thornton (Eds) ISBN: 1 859960545 Published: November ...
Cited by 10 - Web Search - Get it from MIT Libraries - Library Search

Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase … - Full text - MIT Libraries
CA Hobbs, BA Paul, SK Gilmour - Cancer Res, 2002 - cancerres.aacrjournals.org
... JD, Ponder BA, Kouzarides T., Caldas C. Mutations truncating the EP300 acetylase
in ... expression of protooncogenes c-fos, c-myc, and c-jun following polyamine ...
Cited by 10 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

SYSTEMIC MODELING OF BIOLOGICAL FUNCTIONS
COFIB GENES, ORG PRODUCTS - mcxapc.org
... Interaction of MADH3/4 with c-FOS/c-JUN allows TGF?-induced ... the cooperating
transcription factors (X) interact with promoter sequences ; CREBBP/EP300 can act ...
Web Search

Hepatic Temporal Gene Expression Profiling in Helicobacter hepaticus-Infected A/JCr Mice
S BOUTIN, A ROGERS, Z SHEN, R FRY, J LOVE, P … - Toxicologic Pathology, 2004 - dx.doi.org
... Tubulin, beta 3 * * 2.68 Tubulin, beta 5 * * 2.67 CREBBP/EP300 inhibitory protein
1 * 2.24 2.63 Retinoic acid early transcript gamma * 1.69 2.63 ...
Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Candidate nsSNPs That Can Affect the Functions and Interactions of Cell Cycle Proteins - Full text - MIT Libraries
S Savas, MF Ahmad, M Shariff, DY Kim, H Ozcelik - risk - doi.wiley.com
... CDC20, CDC23, CDC25B, CDC2L5, CDC37, CDC40, CDC42, CDC45L, CDC5L, CDC7, CDK2, CDK3,
CDK4, CDK5, CDK6, CDK7, CDK9, CDKN1C, CDKN3, E2F4, E2F6, JUN, MDM2, NFKBIA ...
Web Search - ijmm.org - ncbi.nlm.nih.gov

The p 53 pathway in breast cancer - Full text - MIT Libraries
M Gasco, S Shami, T Crook - Breast Cancer Res, 2002 - dx.doi.org
... A, Thorpe K, Chin SF, Daigo Y, Russell P, Wilson A, Sowter HM, Delhanty JDA, Ponder
BAJ, Kouzarides T, Caldas C: Mutations truncating the EP300 acetylase in ...
Cited by 12 - Web Search - pubmedcentral.nih.gov - breast-cancer-research.com - citebase.eprints.org - all 10 versions »

DNA methylation and chromatin modifications in cancer and development
I Kuzmin, L Geil - Int. Arch. Biosci.(2001) - iabs.us
... A smaller group of genes, including c- jun, c-myc, TCLI protooncogene, carboanhydrases
CA9 and CA12 may become hypomethylated and reactivated in a course of ...
Cited by 3 - View as HTML - Web Search

Identification of Novel Candidate Oncogenes and Tumor Suppressors in Malignant Pleural Mesothelioma … - Full text - MIT Libraries
GJ Gordon, GN Rockwell, RV Jensen, JG Rheinwald, … - American Journal of Pathology, 2005 - ajp.amjpathol.org
... 8 These include the tumor suppressors RASSF1A, NF2, and p16 as well as the growth
factors/proto-oncogenes/signaling molecules c- fos, c-jun, EGF, VEGF, MetAP2 ...
Web Search - ajp.amjpathol.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

The molecular characteristics of polycystic ovary syndrome (PCOS) ovary defined by human ovary cDNA …
FY Diao, M Xu, Y Hu, J Li, Z Xu, M Lin, L Wang, Y … - J Mol Endocrinol, 2004 - njmu.edu.cn
... GenBank ID Gene name Abbreviation Unigene P/N Classification Cell division NM_014335
CREBBP/EP300 inhibitory protein 1 CR11 Hs. 381137 3·12 ...
Cited by 1 - Web Search - jme.endocrinology-journals.org - journals.endocrinology.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Genes, chromatin, and breast cancer: an epigenetic tale
LM Mielnicki, HL Asch, BB Asch - J Mammary Gland Biol Neoplasia, 2001 - kluweronline.com
Page 1. Journal of Mammary Gland Biology and Neoplasia, Vol. 6, No. 2, 2001
Genes, Chromatin, and Breast Cancer: An Epigenetic Tale ...
Cited by 10 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Histone acetylation and disease - Full text - MIT Libraries
S Timmermann, H Lehrmann, A Polesskaya, A Harel- … - Cell. Mol. Life Sci, 2001 - springerlink.com
... Thorpe K., Chin SF et al. (2000) Mutations truncating the EP300 acety-
lase in human cancers. Nat. Genet. 24: 300–303 31 Muraoka ...
Cited by 53 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

p300/CBP proteins: HATs for transcriptional bridges and scaffolds - Full text - MIT Libraries
HM Chan, NB La Thangue - J. Cell Sci, 2001 - jcs.biologists.org
... The recruitment of p300/CBP, together with transcription factors such as ATF2/JUN,
p50/p65 of NF-kB and interferon regulatory factor 1, alongside architectural ...
Cited by 149 - Web Search - jcs.biologists.org - genetics.biol.ttu.edu - ncbi.nlm.nih.gov

1. SYNERGISTIC ANTIGLIOMA ACTIVITY OF INTERLEUKIN-12 AND INTERLEUKIN-18
MOFARIN HUMAN, MGRR CELL, IN VIVO - ingentaconnect.com
... CARBOPLATIN, AND INTERFEREON BETA WITH RADIATION (VAC-FERON-R ) FOR NEWLY DIAGNOSED
GLIOBLASTOMA MULTIFORME Tomokazu Aoki, Tetsuya Ueba, Jun Takahashi, Natstuo ...
Web Search

Histone deacetylase inhibitors: from target to clinical trials
WK Kelly, OA O'Connor, PA Marks - Expert Opinion on Investigational Drugs, 2002 - dx.doi.org
Page 1. Review 2002 © Ashley Publications Ltd ISSN 1354-3784 1695 Ashley
Publications www.ashley-pub.com 1. Introduction 2. Chromatin ...
Cited by 42 - Web Search - ashley-pub.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Acetylation of proteins as novel target for antitumor therapy: - Full text - MIT Libraries
E Di Gennaro, F Bruzzese, M Caraglia, A Abruzzese, … - Amino Acids, 2004 - springerlink.com
... Transcription factors TAT, p53, p73, TCF, GATA-1, RelA, C-Jun, E2F, EKLF, NF ... Ponder
BA, Kouzarides T, Caldas C (2000) Mutations truncating the EP300 acet- ylase ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

Epigenetic and Chromatin Modifiers As Targeted Therapy of Hematologic Malignancies - Full text - MIT Libraries
KN Bhalla - J Clin Oncol, 2005 - jco.org
... 12,13,120-122 The two closely related HATs p300 and CBP are transcriptional co-factors
for several oncoproteins including p53, pRB, Myb, Jun, Fos, and RUNX. ...
Cited by 2 - Web Search - dx.doi.org - jco.org - ncbi.nlm.nih.gov

Epigenetics and cancer - Full text - MIT Libraries
AH Lund, M van Lohuizen - Genes & Development, 2004 - genesdev.org
... The two closely related HATs, p300 and CBP, act as transcriptional cofactors for
a range of cellular oncoproteins, such as MYB, JUN, FOS, RUNX, BRCA1, p53, and ...
Cited by 11 - Web Search - dx.doi.org - genesdev.org - ncbi.nlm.nih.gov

Elucidation of the Mechanism of Side Chain Degradation and Gene Regulatory Functions
N Landes - pub.ub.uni-potsdam.de
... (Ricciarelli et al. 2000) CD95 smooth muscle cells (Lee and Chau 2001) c-Jun human
breast cancer cells (Yu et al. 1998) Collagen alpha 1(I)Mice ...
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