A novel gene, MEL1, mapped to 1p36. 3 is highly homologous to the MDS1/EVI1 gene and is … - Full text - MIT Libraries
N Mochizuki, S Shimizu, T Nagasawa, H Tanaka, M … - Blood, 2000 - bloodjournal.org
... mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and ... Mochizuki, Seiichi
Shimizu, Toshiro Nagasawa, Hideo Tanaka, Masafumi Taniwaki, Jun Yokota, and ...
Cited by 16 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

EVI1 Is Expressed in Megakaryocyte Cell Lineage and Enforced Expression of EVI1 in UT-7/GM Cells … - Full text - MIT Libraries
S Shimizu, T Nagasawa, O Katoh, N Komatsu, J … - Biochem Biophys Res Commun, 2002 - ingentaconnect.com
... EVI1 Is Expressed in Megakaryocyte Cell Lineage and Enforced Expression of
EVI1 in UT-7/GM Cells Induces Megakaryocyte Differentiation. ...
Cited by 4 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

[CITATION] Identification of Translocational Breakpoints within the Intron Region before the Last Coding Exon ( …
K Suzukawa, T Taki, T Abe, H Asoh, N Kamada, J …
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Identification of translocational breakpoints within the intron region before the last coding exon ( … - Full text - MIT Libraries
K Suzukawa, T Taki, T Abe, H Asoh, N Kamada, J … - Genomics, 1997 - ncbi.nlm.nih.gov
... Jun 1;42(2):356-60. ... Click here to read Identification of translocational breakpoints
within the intron region before the last coding exon (exon 12) of the EVI1 ...
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The Evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death - Full text - MIT Libraries
M Kurokawa, K Mitani, T Yamagata, T Takahashi, K … - The EMBO Journal, 2000 - embojournal.npgjournals.com
... Lopingco,MC and Perkins,AS (1996) Molecular analysis of Evi1, a zinc finger ... Zon,L.
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Study on expression of Evi1 and MDS1-Evi1 genes in myelodysplastic syndromes
K Xu, L Wang, Y Hao - Zhonghua Xue Ye Xue Za Zhi, 1998 - ncbi.nlm.nih.gov
1998 Jun;19(6):315-9. ... [Study on expression of Evi1 and MDS1-Evi1 genes in
myelodysplastic syndromes] [Article in Chinese] Xu K, Wang L, Hao Y. Institute of ...
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Identification of a breakpoint cluster region 3'of the ribophorin I gene at 3q21 associated with the … - Full text - MIT Libraries
K Suzukawa, E Parganas, A Gajjar, T Abe, S … - Blood, 1994 - bloodjournal.org
... Kazurni Suzukawa, Evan Parganas, Arnar Gajjar, Tsukasa Abe, Satoshi Takahashi,
Kenzaburo Tani, Shigetaka Asano, Hiroya Asou, Nanao Kamada, Jun Yokota, Kazuhiro ...
Cited by 47 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov - all 5 versions »

Identification of breakpoint cluster regions at 1 p 36. 3 and 3 q 21 in hematologic malignancies …
S Shimizu, K Suzukawa, T Kodera, T Nagasawa, T Abe … - Genes Chromosomes and Cancer, 2000 - doi.wiley.com
... Tanaka, 5 Shin Fujisawa, 6 Bertil Johansson, 7 Tomas Ahlgren, 8 Jun Yokota, 1 ... RPN1)
gene acquires a function to activate the transcription of the EVI1 gene at ...
Cited by 10 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Detection of t (3; 21)(q26; q22) with AML1/EVI1 mRNA during progression of myelodysplastic syndrome …
I Choi, T Goto, M Nagano, K Muta, Y Yufu, N Uike, … - Rinsho Ketsueki, 1999 - ncbi.nlm.nih.gov
1999 Jun;40(6):518-20. ... [Detection of t(3 ; 21) (q26 ; q22) with AML1/EVI1 mRNA during
progression of myelodysplastic syndrome to acute myeloid leukemia ...
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Recurrent retroviral vector integration at the MDS1-EVI1 locus in non-human primate hematopoietic … - Full text - MIT Libraries
B Calmels, C Ferguson, MO Laukkanen, R Adler, M … - Blood, 2005 - ncbi.nlm.nih.gov
2005 Jun 2; [Epub ahead of print], ... Click here to read Recurrent retroviral vector
integration at the MDS1-EVI1 locus in non-human primate hematopoietic cells. ...
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Advances in the study of Evi1 and mds1 genes
K Xu, L Wang, Y Hao - Zhonghua Xue Ye Xue Za Zhi, 1999 - ncbi.nlm.nih.gov
Zhonghua Xue Ye Xue Za Zhi. 1999 Jun;20(6):331-3. ... [Advances in the study of Evi1
and mds1 genes] [Article in Chinese] Xu K, Wang L, Hao Y. Publication Types: ...
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Expression of the TEL/EVI1 Fusion Transcript in a Patient With Chronic Myelogenous Leukemia With t ( …
Y Nakamura, H Nakazato, Y Sato, S Furusawa, K … - American Journal of Hematology, 2002 - doi.wiley.com
... 3. Nucifora G. The EVI1 gene in myeloid leukemia. ... Izutsu K, Ogawa S, Moriguchi T,
Nishida E, Yazaki Y, Hirai H. The Evi-1 oncoprotein inhibits c-Jun N-terminal ...
Cited by 1 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Ecotropic viral integration site-1 is activated during, and is sufficient for, neuroectodermal P19 … - Full text - MIT Libraries
H Kazama, T Kodera, S Shimizu, H Mizoguchi, K … - Cell Growth Differ, 1999 - cgd.aacrjournals.org
... We could not, however, conclude whether transcriptional activation of the c-jun
gene by enforced Evi1 expression is related to regulation of the neural ...
Cited by 4 - Web Search - cgd.aacrjournals.org - ncbi.nlm.nih.gov

Quantitative comparison of the expression of EVI1 and its presumptive antagonist, MDS1/EVI1, in …
U Vinatzer, C Mannhalter, M Mitterbauer, H Gruener … - Genes Chromosomes Cancer, 2003 - doi.wiley.com
Page 1. Quantitative Comparison of the Expression of EVI1 and Its Presumptive
Antagonist, MDS1/EVI1, in Patients with Myeloid Leukemia ... extent than that of EVI1. ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Molecular Detection of TEL-AML 1 Transcripts as a Diagnostic Tool and for Monitoring of Minimal … - Full text - MIT Libraries
HJ Park, KE Lee, JM Um, SY Choe, XZ Chi, JA Lee, … - Molecules and Cells, 2000 - springerlink.com
... 1 , Jung Min Um 1 , Soo Young Choe 2 , Xin Zi Chi 4 , Jun Ah Lee ... The translocations
involving AML1 produce chimeric proteins: AML1-Evi1, AML1- MDS1 or AML1-EAP ...
Cited by 3 - Web Search - 192.129.24.144 - 194.94.42.12 - ncbi.nlm.nih.gov - all 5 versions »

Oligo GEArray® Human TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... IGFBP3, IL6, INHA, INHBA, INHBB, INHBC, PDGFB, PLAU, SERPINE1 Transcription Factors
and Regulators: DLX2, EVI1, FOS, GSC, HIPK2, ID1, ID3, ID4, JUN, JUNB, MYC ...
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Oligo GEArray® Rat TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... Col1a1, Col1a2, Col3a1, Fos, Gsc, Igf1, Igfbp3, Il6, Itgb7, Ivl, Jun, Junb, Myc ...
TGF-β superfamily: Bambi, Cdkn2b, Chrd, Cktsf1b1, Cst3, Eng, Evi1, Fkbp1b, Fmod ...
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Oligo GEArray® Mouse TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... Col1a1, Col1a2, Col3a1, Fos, Gsc, Igf1, Igfbp3, Il6, Itgb7, Ivl, Jun, Junb, Myc ... of
TGF-β superfamily: Bambi, Bmper, Cdkn2b, Cer1, Chrd, Eng, Evi1, Fkbp1b, Fst ...
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Identification of a zinc finger protein whose subcellular distribution is regulated by serum and … - Full text - MIT Libraries
A Chittka, MV Chao - Cell, 1999 - dx.doi.org
... PRDI-BF1/Blimp-1 protein, the Caenorhabditis elegans egl-43 and EVI1 gene products ...
C. Gustafson-Brown, RS Johnson, R. Wisdom, and BD Carter c-jun is essential ...
Cited by 41 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

GEArray Q Series Human TGFβ BMP Signaling Pathway Gene Array Cat. No.* Kit Size HS-023-2/HS-023N-2 …
FG Grouping - tebu-bio.com
... TGF- β superfamily: CER1 (cerberus), CHRD (chordin), CKTSF1B1 (gremlin), ENG (endoglin),
EVI1 (Evi-1 ... of TGF-beta/BMP signaling, J Cell Physiol 2001 Jun; 187 (3 ...
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GEArray Q Series Mouse TGFβ BMP Signaling Pathway Gene Array Cat. No.* Kit Size MM-023-2/MM-023N-2 …
FG Grouping - tebu-bio.com
... Bambi (Nma), Cer1 (cerberus), Chrd (chordin), Cktsf1b1 (gremlin), Eng (endoglin),
Evi1 (Evi-1), Fkbp1b ... of TGF-beta/BMP signaling, J Cell Physiol 2001 Jun; 187 (3 ...
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The leukaemia-associated transcription factors EVI-1 and MDS 1/EVI 1 repress transcription and … - Full text - MIT Libraries
U Vinatzer, J Taplick, C Seiser, C Fonatsch, R … - British Journal of Haematology, 2001 - blackwell-synergy.com
... MDS1/EVI1, on the other hand, enhanced TGF- -dependent effects ( Sood et al, 1999 ...
has been suggested by its ability to interact with and inhibit jun N-terminal ...
Cited by 5 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

GEArray Q Series Mouse TGFβ BMP Signaling Pathway Gene Array: AR-SAMM-023
FG Grouping - eurogentec.be
... Bambi (Nma), Cer1 (cerberus), Chrd (chordin), Cktsf1b1 (gremlin), Eng (endoglin),
Evi1 (Evi-1), Fkbp1b ... of TGF-beta/BMP signaling, J Cell Physiol 2001 Jun; 187(3 ...
View as HTML - Web Search - eurogentec.com

GEArray Q Series Human TGFβ BMP Signaling Pathway Gene Array: AR-SAHS-023
FG Grouping - eurogentec.com
... TGF-β superfamily: CER1 (cerberus), CHRD (chordin), CKTSF1B1 (gremlin), ENG (endoglin),
EVI1 (Evi-1 ... of TGF-beta/BMP signaling, J Cell Physiol 2001 Jun; 187 (3 ...
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Tumourigenicity of MTG 8, a leukaemia-related gene, in concert with v-Ha-ras gene in BALB/3 T 3 … - Full text - MIT Libraries
E Sueoka, N Sueoka, S Okabe, A Komori, M Suganuma, … - British Journal of Haematology, 1998 - blackwell-synergy.com
... Thus, both the AML1/MTG8 gene and the AML1/Evi1 gene are unique chimaeric ... such as
Raf/MAP kinases, stress-activated protein kinase (SAPK), and c-Jun N-terminal ...
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Progress in Hematology
T Yamagata, K Maki, K Mitani - Int J Hematol, 2005 - cardenjennings.metapress.com
... Three of the 4 fusion molecules,Runx1-ETO in t(8;21),Runx1-Evi1 in t(3;21 ... has been
reported to enhance the expression of genes such as C/EBP , c-Jun, and TRKA ...
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HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor - Full text - MIT Libraries
AH Wang, NR Bertos, M Vezmar, N Pelletier, M … - Mol. Cell. Biol, 1999 - mcb.asm.org
... and HDAC4 individually upregulate but together downmodulate c-jun promoter activity. ...
Groucho homolog TLE1 (12, 48), zinc finger oncoprotein Evi1 (3), Polycomb ...
Cited by 96 - Web Search - pubmedcentral.nih.gov - faculty.biu.ac.il - ncbi.nlm.nih.gov - all 6 versions »

Role of molecular screening for common fusion genes in the diagnosis and classification of leukemia.
YL Zhu, Y Zhang, P Zhu, Y Yang, DU JW, J Liu - Beijing Da Xue Xue Bao, 2005 - ncbi.nlm.nih.gov
2005 Jun 18;37(3):236-9 ... of leukemia, including AML1/ETO, PML/RARalpha, PLZF/RARalpha,
dupMLL, MLL/AF6, MLL/AF10, CBFbeta/MYH11, BCR/ABL, Hox11, and EVI1 BCR/ABL ...
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Occurrence of leukaemia following gene therapy of X-linked SCID - Full text - MIT Libraries
DB Kohn, M Sadelain, JC Glorioso - Nature Reviews Cancer, 2003 - nature.com
... 1 Jun 2003 (doi:10.1038/ng1179). ... The retroviral vector was inserted near the Evi1
locus -- a gene that is associated with acute myeloid leukaemia. ...
Cited by 43 - Web Search - nature.com - ncbi.nlm.nih.gov - csa.com

GEArray S Series Mouse Autoimmune and Inflammatory Response Gene Array: AR-SAMM-602.3
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.com
... Camk2b, Camk4, Cdc25a, Cdkn1a, Cdkn2b, Chuk, Csnk2a1, Csnk2b, Eng, Evi1, Gsk3a-Rik ...
Fkbp1b, Fos, Fosb, Fosl1, Fosl2, Gata3, Gata4, Icos, Irf1, Jun, Junb, Jund1 ...
View as HTML - Web Search - eurogentec.be

GEArray S Series Human Autoimmune and Inflammatory Response Gene Array: AR-SAHS-602
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.be
... CAMK2B, CAMK4, CDC25A, CDKN1A, CDKN2B, CHUK, CSNK2A1, CSNK2B, ENG, EVI1, GSK3A,
GSK3B ... FOS, FOSL1, FOSL2, FOXP3, GATA3, GATA4, GRLF1, ICOS, IRF1, JUN, JUNB, JUND ...
View as HTML - Web Search - eurogentec.com

Four of the seven zinc fingers of the Evi-1 myeloid-transforming gene are required for sequence- … - Full text - MIT Libraries
R Delwel, T Funabiki, BL Kreider, K Morishita, JN … - Mol. Cell. Biol, 1993 - pubmedcentral.nih.gov
... Activation of EVI1 gene expression in human acute myelogenous leukemias by
translocations spanning 300-400 kilobases on ... Nature 1989 Jun 8;339(6224):446–451. ...
Cited by 32 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34 cells, allowing nerve growth …
JC Mulloy, V Jankovic, M Wunderlich, R Delwel, J … - pnas.org
... the formation of the AML1-ETO (RUNX1-CBFA2T1) [t(8;21)], RUNX1/MDS/EVI1 [t(3 ... activator
in certain cellular contexts, perhaps by up-regulating c-JUN activity (22 ...
Web Search - dx.doi.org - dx.doi.org - pnas.org

The EVI 1 gene in myeloid leukemia
G Nucifora - Leukemia, 1997 - nature.com
... However, recently it was shown that one of the downstream effects of EVI1 in NIH
3T3 and P19 cells is to increase the expression of endogenous c-Jun and c-Fos ...
Cited by 41 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Rearrangements of Chromosome Band 3 q 21 in Myeloid Leukemia
R Wieser - Leukemia & Lymphoma, 2002 - dx.doi.org
... and Nucifora, C. (1999) “Forced expression of the leukemia-associated gene EVI1
in ES ... and Hirai, H. (2000) “The evi-1 oncoprotein inhibits c-Jun N-terminal ...
Cited by 4 - Web Search - taylorandfrancis.metapress.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The incidence of trisomy 3 in splenic lymphoma with villous lymphocytes: a study by FISH - Full text - MIT Libraries
AM GRUSZKA-WESTWOOD, E MATUTES, LJA COIGNET, A … - British Journal of Haematology, 1999 - blackwell-synergy.com
... Whittaker, MH, Drabkin, H., Oval, J., Taetle, R., Valentine, MB & Ihle, JN (1992)
Activation of EVI1 gene expression ... Online publication date: 1 - Jun - 2004 . ...
Cited by 18 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

A comparative analysis of relative occurrence of transcription factor binding sites in vertebrate … - Full text - MIT Libraries
M Stepanova, T Tiazhelova, M Skoblov, A Baranova - Bioinformatics, 2005 - bioinformatics.oxfordjournals.org
... also indicative of positive selection for EVI1 TFBS in the mouse lineage. On the
other hand, binding sites for factors STAT1, STAT3 and V-JUN were positively ...
Web Search - bioinformatics.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Functional dissection of the alpha and beta subunits of transcription factor PEBP 2 and the redox … - Full text - MIT Libraries
H Kagoshima, Y Akamatsu, Y Ito, K Shigesada - J Biol Chem, 1996 - jbc.org
... and mercaptoethanol or by cellular redox cofactors, Ref1/APEX for Jun/Fos (34 ... longer
isoform AML1b (equivalent to mouse B1) and the AML1-Evi1 chimeric protein ...
Cited by 59 - Web Search - jbc.org - ncbi.nlm.nih.gov

Signaling of transforming growth factor-b family members through Smad proteins
S Itoh, F Itoh, MJA Goumans, P ten Dijke - cancer - ingentaconnect.com
... [107, 109] [104] Transcription factor ATF-2 c-Fos c-Jun, JunB, JunD C-terminally
truncated Gli3 GR VDR E1A Evi1 FAST Lef1/Tcf Milk Mixer ...
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Computational BAC clone contig assembly for comprehensive genome analysis
A Lapuk, S Volik, R Vincent, K Chin, WL Kuo, P de … - Genes Chromosomes and Cancer, 2004 - doi.wiley.com
... The region of amplification encompassing 200 kb and containing the EVI1 oncogene
is ... The evi-1 oncoprotein inhibits c-jun n-terminal kinase and prevents stress ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Point mutations of the Runt domain as a means to improve solubility and enable structure …
M HAMMARSTROeM - ibg.uu.se
... kind of regulation has been described in a number of transcription factors, like
Jun/Fos, Myb, NF ... The t(3;21) fusion of one of the EAP, MDSI or EVI1 proteins to ...
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Sox4 blocks cytokine-induced differentiation of 32Dcl3 cells and is a possible cooperating partner …
KE Boyd, A Poholek, O Mironenko, NG Copeland, NA … - yalepath.org
... Myeloid leukemias arising in AKXD23 mice contain proviral insertions at Evi1, which ...
Evi1 can induce leukemia, arguing that cooperating events are necessary. ...
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NEW EMBO MEMBER'S REVIEW Transcriptional control by the TGF-b/Smad signaling system - Full text - MIT Libraries
J MassagueA, D Wotton - The EMBO Journal, 2000 - emboj.org
... JNK and p38, which in turn regulate the activity of Fos, Jun and ATF-2 ... The
zinc-®nger transcriptional repressor protein Evi1, which also exists as a truncated ...
Cited by 107 - Web Search - nature.com

NEW EMBO MEMBER’S REVIEW - Full text - MIT Libraries
J Massague, D Wotton - The EMBO Journal, 2000 - embojournal.npgjournals.com
... JNK and p38, which in turn regulate the activity of Fos, Jun and ATF-2 ... The zinc-finger
transcriptional repressor protein Evi1, which also exists as a truncated ...
Cited by 4 - Web Search - emboj.org - pubmedcentral.nih.gov

Chromosomal Translocations in Hematologic Malignancies
CG Brunstein, SJ Dylla, CM Verfaillie - Current Genomics, 2002 - ingentaconnect.com
Page 1. Current Genomics, 2002, 3, 313-334 313 1389-2029/02 $35.00+.00 © 2002
Bentham Science Publishers Ltd. Chromosomal Translocations ...
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A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... IRF2 01 Interferon regulatory factor 2 Core should be AAGYGAAA not GAAA EVI1 06
Ectopic viral integration site 1 encoded factor Core should be ACAAGAT not AGAT ...
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Signaling of transforming growth factor-beta family members through Smad proteins - Full text - MIT Libraries
S Itoh, F Itoh, MJ Goumans, P ten Dijke - European Journal of Biochemistry, 2000 - content.febsjournal.org
... 88], as well as negative, eg by binding proto-oncogene products Evi1 [120], Ski ... receptor;
HGF, hepatocyte growth factor; IFN, interferon; JNK, c-jun N-terminal ...
Cited by 95 - Cached - Web Search - ejbiochem.org - blackwell-synergy.com - ncbi.nlm.nih.gov - all 6 versions »

Smad-dependent and Smad-independent pathways in TGF-b family signalling - Full text - MIT Libraries
R Derynck, YE Zhang - Nature, 2003 - nature.com
... 25). Jab1, the CSN5 subunit of the COP9 signalosome that was initially identified
as a coactivator for c-Jun, has been implicated in targeting Smad4 for ...
Cited by 172 - Web Search - nature.com - ucsf.edu - ncbi.nlm.nih.gov - all 5 versions »

The t (3; 21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor … - Full text - MIT Libraries
M Kurokawa, K Mitani, Y Imai, S Ogawa, Y Yazaki, H … - Blood, 1998 - bloodjournal.org
... For example, it was reported that c-Jun inhibits myogenesis by interfering with
the ... Oval J, Taetle R, Valentine MB, Ihle JN: Activation of EVI1 gene expression ...
Cited by 32 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t (3; 21) … - Full text - MIT Libraries
T Tanaka, K Mitani, M Kurokawa, S Ogawa, K Tanaka, … - Mol. Cell. Biol, 1995 - mcb.asm.org
... by AML1/Evi-1 should be correlated with cellular transformation, because
AML1/Evi-1- expressing fibroblast cells show increased c-jun transcripts and anchorage ...
Cited by 56 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov