The International Neuroblastoma Pathology Classification(the Shimada system)
H Shimada, IM Ambros, LP Dehner, J Hata, VV Joshi, … - Cancer, 1999 - doi.wiley.com
... MD, Ph.D. 1 Inge M. Ambros, MD 2 Louis P. Dehner, MD 3 Jun-ichi Hata ... Forty-two tumors
had ampli- fied MYCN, 152 had nonamplified MYCN, and the MYCN test was not ...
Cited by 105 - Web Search - doi.wiley.com - reprints.nant.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Terminology and morphologic criteria of neuroblastic tumors
H Shimada, IM Ambros, LP Dehner, J Hata, VV Joshi, … - Cancer, 1999 - doi.wiley.com
... Hiroyuki Shimada, MD, Ph.D. 1 Inge M. Ambros, MD 2 Louis P. Dehner, MD 3 Jun-ichi
Hata ... chromosome 1 short arm, lack of MYCN amplification, and near-triploidy. ...
Cited by 75 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Telomerase activity and telomerase subunits gene expression patterns in neuroblastoma: a molecular … - Full text - MIT Libraries
C Poremba, C Scheel, B Hero, H Christiansen, KL … - J Clin Oncol, 2000 - jco.org
... Scheel , Barbara Hero , Holger Christiansen , Karl-Ludwig Schaefer , Jun-ichi Nakayama ...
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… profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma - Full text - MIT Libraries
QR Chen, S Bilke, J Wei, C Whiteford, N Cenacchi, … - BMC Genomics, 2004 - biomedcentral.com
... array-CGH profiling identifies genomic alterations specific to stage and
MYCN-amplification in neuroblastoma Qing-Rong Chen * 1 , Sven Bilke * 1 , Jun S ...
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Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast … - Full text - MIT Libraries
FJ Couch, XY Wang, GJ Wu, J Qian, RB Jenkins, CD … - Cancer Res, 1999 - cancerres.aacrjournals.org
... Fergus J. Couch , Xiao-Yang Wang , Guo-Jun Wu , Junqi Qian , Robert B. Jenkins ... which
resides within a region that can be coamplified with MYCN in neuroblastoma ...
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MYCN is retained in single copy at chromosome 2 band p23–24 during amplification in human … - Full text - MIT Libraries
R Corvi, LC Amler, L Savelyeva, M Gehring, M … - Proc Natl Acad Sci US, 1994 - pubmedcentral.nih.gov
... the view that either the initial events of MYCN amplification or the further evolution
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PPM1D is a potential target for 17q gain in neuroblastoma - Full text - MIT Libraries
F Saito-Ohara, I Imoto, J Inoue, H Hosoi, A … - Cancer Res, 2003 - cancerres.aacrjournals.org
... Fumiko Saito-Ohara 2 , Issei Imoto 2 , Jun Inoue , Hajime Hosoi , Akira ... of genetic
abnormalities, which may include amplification of the MYCN gene, deletion of ...
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Sustained expression of the human protooncogene MYCN rescues rat embryo cells from senescence. - Full text - MIT Libraries
M Schwab, JM Bishop - Proc Natl Acad Sci US A, 1988 - pubmedcentral.nih.gov
... protooncogene, and identify an additional biological activity that can be used in
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Prediction of Clinical Outcome Using Gene Expression Profiling and Artificial Neural Networks for … - Full text - MIT Libraries
JS Wei, BT Greer, F Westermann, SM Steinberg, CG … - Cancer Res, 2004 - cancerres.aacrjournals.org
... Jun S. Wei 1 , Braden T. Greer 1 , Frank Westermann 2 , Seth M ... analysis we identified
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BMC Genomics - Full text - MIT Libraries
QR Chen, S Bilke, JS Wei, CC Whiteford, N Cenacchi … - BMC Genomics, 2004 - biomedcentral.com
... to stage and MYCN-amplification in neuroblastoma Qing-Rong Chen †1 , Sven
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Altered expression of cell cycle genes distinguishes aggressive neuroblastoma - Full text - MIT Libraries
AL Krasnoselsky, CC Whiteford, JS Wei, S Bilke, F … - Oncogene, 2005 - nature.com
... Alexei L Krasnoselsky 1,3 , Craig C Whiteford 1,3 , Jun S Wei 1 ... on 103 neuroblastoma
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Regions syntenic to human 17q are gained in mouse and rat neuroblastoma
M Lastowska, YJ Chung, NC Ching, M Haber, MD … - Genes Chromosomes Cancer, 2004 - doi.wiley.com
... Maria Lastowska, 1 * Yeun-Jun Chung, 2 Ngan Cheng Ching, 3 Michelle Haber, 3 ... in up
to 30% of neuroblastoma tumors developed in a murine MYCN transgenic model ...
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Definition and characterization of a region of 1 p 36. 3 consistently deleted in neuroblastoma - Full text - MIT Libraries
PS White, PM Thompson, T Gotoh, ER Okawa, J … - Oncogene, 2005 - nature.com
... 1,2 , Patricia M Thompson 1 , Takahiro Gotoh 1 , Erin R Okawa 1 , Jun Igarashi 1 ...
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Full record
C Qing-Rong, B Sven, W Jun, W Craig, C Nicola, K … - doaj.org
... identifies genomic alterations specific to stage and MYCN -amplification in
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Histologic survey of neuroblastomas after intensive induction chemotherapy.
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... Jun Sakamoto, MD , 1 Makoto Suzuki, MD , 1 and Toshiji Shitara, MD 3 ... of age with
stage 3/4 disease, and 4 were <12 months of age but with MYCN- amplified stage ...
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Localization of regulatory elements controlling human MYCN expression
S Hiller, S Breit, ZQ Wang, EF Wagner, M Schwab - Oncogene, 1991 - ncbi.nlm.nih.gov
Oncogene. 1991 Jun;6(6):969-77. ... Localization of regulatory elements controlling
human MYCN expression. Hiller S, Breit S, Wang ZQ ...
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Fluorescence in situ hybridization (FISH) detection of MYCN oncogene amplification in neuroblastoma …
DN Misra, PS Dickman, EJ Yunis - Diagn Mol Pathol, 1995 - ncbi.nlm.nih.gov
1995 Jun;4(2):128-35. ... Fluorescence in situ hybridization (FISH) detection of MYCN
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BRIEF REPORTS Prognostic Significance of Elevated Lactate Dehydrogenase and Creatine Kinase in …
H Moritake, S Kamimura, K Akiyoshi, Y Nagatoshi, H … - Med Pediatr Oncol, 2003 - doi.wiley.com
... Research, National Kyushu Cancer Center, Fukuoka, Japan *Correspondence to: Jun
Okamura, Institute ... prognostic markers of RMS, such as desmin [9], MYCN [10,11 ...
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Amplified MYCN in human neuroblastoma: paradigm for the translation of molecular genetics to … - Full text - MIT Libraries
M Schwab - Ann NY Acad Sci, 2002 - ncbi.nlm.nih.gov
2002 Jun;963:63-73. ... Click here to read Amplified MYCN in human neuroblastoma: paradigm
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Application of fluorescence in situ hybridization to detect N-myc(MYCN) gene amplification on …
Y Hachitanda, M Saito, T Mori, M Hamazaki - Medical and Pediatric Oncology, 1997 - doi.wiley.com
... of the tumor [1,2]. In order to detect N-myc (MYCN) amplifi- cation ... The authors thank
Jun-ichi Hata, MD, Keio Univer- sity, Jun-ichiro Fujimoto, MD, National ...
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In vitro effects of MYCN sense and antisense expression in MYCN-amplified human neuroblastoma cells
M Kavallaris, M Gardaneh, B Cheung, ML Camacho, JE … - Anticancer Res, 1998 - ncbi.nlm.nih.gov
Anticancer Res. 1998 May-Jun;18(3A):1793-7. ... In vitro effects of MYCN sense and
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Unfavorable prognostic factors associated with high frequency of microsatellite instability and … - Full text - MIT Libraries
A Hirasawa, D Aoki, J Inoue, I Imoto, N Susumu, K … - Clin Cancer Res, 2003 - clincancerres.aacrjournals.org
... Akira Hirasawa 12 , Daisuke Aoki 2 , Jun Inoue 13 , Issei Imoto 13 , Nobuyuki Susumu ...
of EACs with MSI-H. Southern blotting showed amplification of MYCN in one ...
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The MYCN Oncogene as a Specific and Selective Drug Target for Peripheral and Central Nervous System …
A Pession, R Tonelli - Curr Cancer Drug Targets, 2005 - ncbi.nlm.nih.gov
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MycN sensitizes neuroblastoma cells for drug-triggered apoptosis
S Fulda, W Lutz, M Schwab, KM Debatin - Medical and Pediatric Oncology, 2000 - doi.wiley.com
... McMahon G. Regulation of Myc- dependent apoptosis by p53, c-Jun N-terminal ... Altered
expression of the MYCN oncogene modulates MRP gene expression and response ...
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The prognostic effect of amplification of the MYCN oncogene in neuroblastoma. The preliminary …
A Pession, B De Bernardi, P Perri, K Mazzocco, R … - Pediatr Med Chir, 1994 - ncbi.nlm.nih.gov
Pediatr Med Chir. 1994 May-Jun;16(3):211-8. ... [The prognostic effect of amplification
of the MYCN oncogene in neuroblastoma. The preliminary ...
Web Search - Get it from MIT Libraries

PLEIOTROPIC OVER-EXPRESSION OF MULTIDRUG-RESISTANCE-RELATED GENES IS CORRELATED TO MYCN AND max mRNA … - Full text - MIT Libraries
D Cappellen, J Benard - Int. J. Cancer, 1997 - doi.wiley.com
... implies that MRP may be transcriptionally regulated by the MYCN oncoprotein itself ...
in metastatic murine rhabdomyosar- coma (Hanania et al., 1991): c-jun, c-fos ...
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… phosphatidylethanolamine enhances HL-60 cell differentiation by regulation of c-jun and c-myc …
H Ishigamori, M Hosokawa, H Kohno, T Tanaka, K … - springerlink.com
... G: Decrease of proliferation rate and induction of differentiation by a MYCN antisense
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Megabase-scale analysis of the origin of N-myc amplicons in human neuroblastomas - Full text - MIT Libraries
K Akiyama, N Kanda, M Yamada, K Tadokoro, T … - Nucleic Acids Res, 1994 - pubmedcentral.nih.gov
... Proc Natl Acad Sci USA 1985 Jun;82(11):3761–3765 ... K, Kanda N, Yamada M, Kato M, Tadokoro
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Database of mRNA gene expression profiles of multiple human organs - Full text - MIT Libraries
CG Son, S Bilke, S Davis, BT Greer, JS Wei, CC … - Genome Research, 2005 - genome.org
... 4 , Sven Bilke 1 ,4 , Sean Davis 3 , Braden T. Greer 1 , Jun S. Wei 1 ... profiles of
100 NB tumors of different stages (1 through 4 including MYCN amplified tumors ...
Web Search - dx.doi.org - genome.org - ncbi.nlm.nih.gov

Expression of the woodchuck N-myc2 retroposon in brain and in liver tumors is driven by a cryptic N- … - Full text - MIT Libraries
G Fourel, C Transy, BC Tennant, MA Buendia - Mol. Cell. Biol, 1992 - pubmedcentral.nih.gov
... Full Text]; Hiller S, Breit S, Wang ZQ, Wagner EF, Schwab M. Localization of regulatory
elements controlling human MYCN expression. Oncogene 1991 Jun;6(6):969 ...
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Molecular Profiling of Inflammatory Breast Cancer - Full text - MIT Libraries
I Bieche, F Lerebours, S Tozlu, M Espie, M Marty, … - Clinical Cancer Research, 2004 - clincancerres.aacrjournals.org
... The 27 up-regulated genes mainly encoded transcription factors (JUN, EGR1, JUNB,
FOS, FOSB, MYCN, and SNAIL1), growth factors (VEGF, DTR/HB-EGF, IGFBP7, IL6 ...
Web Search - clincancerres.aacrjournals.org - ncbi.nlm.nih.gov

Cancer-linked genes: Ninth Colloquium on Cellular Signal Transduction: DKFZ Heidelberg, February 4, … - Full text - MIT Libraries
F Marks - Journal of Cancer Research and Clinical Oncology, 2000 - springerlink.com
... Key words Papilloma virus á p53 á Wilm's tumor á FHIT á BRCA2 á Cyclooxygenase-2
á Ras á Myc á MYCN á Jun á TGF-b receptor á Drosophila tumor genes ...
Web Search - ncbi.nlm.nih.gov

Elimination of extrachromosomally amplified MYC genes from human tumor cells reduces their … - Full text - MIT Libraries
DD Von Hoff, JR McGill, BJ Forseth, KK Davidson, … - Proc Natl Acad Sci US A, 1992 - pubmedcentral.nih.gov
... J Clin Invest 1990 Jun;85(6):1887–1895. ... Ability of circular extrachromosomal DNA
molecules to carry amplified MYCN proto-oncogenes in human neuroblastomas in ...
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Molecular structure and evolution of double-minute chromosomes in methotrexate-resistant cultured … - Full text - MIT Libraries
PJ Hahn, B Nevaldine, JA Longo - Mol. Cell. Biol, 1992 - pubmedcentral.nih.gov
... Cell 1989 Jun 16;57(6):901–908. ... Ability of circular extrachromosomal DNA molecules
to carry amplified MYCN proto-oncogenes in human neuroblastomas in vivo. ...
Cited by 5 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

Virtual Genome Scan: A Tool for Restriction Landmark-Based Scanning of the Human Genome - Full text - MIT Libraries
JM Rouillard, AE Erson, R Kuick, J Asakawa, K … - Genome Research, 2001 - genome.org
... Rouillard, 1 Ayse E. Erson, 2 Rork Kuick, 1 Jun-ichi Asakawa ... Neuroblastoma cells
can actively eliminate supernumerary MYCN gene copies by micronucleus formation ...
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Mutations in EFHC 1 cause juvenile myoclonic epilepsy - Full text - MIT Libraries
T Suzuki, AV Delgado-Escueta, K Aguan, ME Alonso, … - Nature Genetics, 2004 - nature.com
... Escueta 3 , Kripamoy Aguan 1, 12 , Maria E Alonso 4 , Jun Shi 1 ... PCR using Pyrobest
(TaKaRa) and cloned it into pEGFPC2 (Clontech), pcDNA3-MycN (Invitrogen) or ...
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Comparative genomic hybridization and telomerase activity analysis identify two biologically …
C Brinkschmidt, C Poremba, H Christiansen, R Simon … - Br J Cancer, 1998 - ncbi.nlm.nih.gov
1998 Jun;77(12):2223-9 ... MYCN amplification or 1p deletion was observed in only 1/27
or 2/17 clinically non-progressing stage 4s tumours respectively, whereas all ...
Cited by 36 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Double minute chromosomes carrying the human multidrug resistance 1 and 2 genes are generated from … - Full text - MIT Libraries
PV Schoenlein, DW Shen, JT Barrett, I Pastan, MM … - Mol Biol Cell, 1992 - pubmedcentral.nih.gov
... Ability of circular extrachromosomal DNA molecules to carry amplified MYCN
proto-oncogenes in human neuroblastomas in ... J Clin Invest 1990 Jun;85(6):1887–1895. ...
Cited by 17 - Web Search - molbiolcell.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Expression of leucocyte adhesion molecules on 66 clinical neuroblastoma specimens
MC Favrot, V Combaret, E Goillot, E Tabone, E … - Int J Cancer, 1991 - ncbi.nlm.nih.gov
1991 Jun 19;48(4):502-10. ... HLA.ABC and LFA-3 expressed on both mycN-negative and
-positive specimens, whereas ICAM-1 was restricted to MYCN-negative specimens. ...
Cited by 6 - Web Search - Get it from MIT Libraries

BMC Genomics - Full text - MIT Libraries
C Cheadle, J Fan, YS Cho-Chung, T Werner, J Ray, L … - BMC Genomics, 2005 - biomedcentral.com
... BCL2A1 CASP10 CASP3 CASP9 CD69 DAP EGR1 EGR2 ETR101 IGF2 IGF2R IL4R IL6 IL8 IRF5
JUN JUNB JUND MYB MYCN NFKBIA PPP3CC STAT4 STAT6 0 min 60min EGR1 (107bp) ...
View as HTML - Web Search - bmc.ub.uni-potsdam.de

Nervous system tumors: Neuroblastoma
F Protein - caroll.vjf.cnrs.fr
... Nat Genet. 1993 Jun;4(2):187-90. Medline 93350639. ... Med Pediatr Oncol. 1999; 33:
357-359. Allelic deletion at 11q23 is common in MYCN single cop y neuroblastomas. ...
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Generation of protein isoform diversity by alternative initiation of translation at non-AUG codons - Full text - MIT Libraries
C Touriol, S Bornes, S Bonnal, S Audigier, H Prats … - Biol. Cell, 2003 - biolcell.org
... growth factor; MYC, v-myc myelocytomatosis viral oncogene homologue; MYCN, v-myc ...
leukaemia derived sequence 1; Egr1, early growth response 1; Jund, Jun D proto ...
Cited by 7 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Isolation and structural analysis of a 1.2-megabase N-myc amplicon from a human neuroblastoma - Full text - MIT Libraries
SS Schneider, JL Hiemstra, BA Zehnbauer, P Taillon … - Mol. Cell. Biol, 1992 - pubmedcentral.nih.gov
... Cell 1989 Jun 16;57(6):901–908. ... Ability of circular extrachromosomal DNA molecules
to carry amplified MYCN proto-oncogenes in human neuroblastomas in vivo. ...
Cited by 15 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

31 Differential response of sensory and motor axons in nerve allografts after withdrawal of …
R Midha, S Nag, CA Munro, LC Ang, H Ohta, Y … - J Neurosurg, 2001 - ijp-online.com
... 2000 Jun;73 Suppl():S98-100. ... 35, Gene amplification in PNETs/medulloblastomas:
mapping of a novel amplified gene within the MYCN amplicon. ...
Cited by 2 - Cached - Web Search - ijp-online.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

11 Oculopharyngeal muscular dystrophy.
AK Sarkar, SK Biswas, AK Ghosh, P Mitra, SK Ghosh, … - Indian J Pediatr, 1995 - ijp-online.com
... 13, Lysis of MYCN-amplified neuroblastoma cells by MYCN peptide-specific cytotoxic
T lymphocytes. Sarkar AK, Nuchtern JG. Cancer Res. ... 1999 May-Jun ;6(3):220-7. ...
Cached - Web Search - ijp-online.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Metastatic adrenal neuroblastoma in an adult.
A Franke, K Jentsch-Ullrich, E Schalk, M Mohren, M … - ncbi.nlm.nih.gov
2005 Jun;28(6-7):353-5. Epub 2005 Jun 2 ... prognostic factors include age > 1 year,
low histologic grade and advanced stage, MYCN amplification, chromosomal ...
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GEArray Q Series Human Hypoxia Signaling Pathway Gene Array: AR-SAHS-032
FG Grouping, S Response, AZU ADM, S Transduction, … - eurogentec.com
... EPO, GAP43, GAPD, GPI, GPX1, HK2, HMOX1, ID2, IGF2, IGFBP1, KIT (c-kit), LCT, LEP
(leptin), LIPE, MYCN, NOTCH1, NPY ... Biochem J. 2002 Jun 1; 364 (Pt 2): 449-56. ...
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Meeting Report of the 2000 International Congress of Pediatric Hematology/Oncology: Shanghai …
P Shearer, LJ Gu, CH Pui - Journal of Pediatric Hematology/Oncology, 2001 - jpho-online.com
... Dr. Long-Jun Gu (Shanghai Children's Medical Center) discussed variability among
patients ... IV disease (73% ± 38% for those with non-amplified MYCN; 51% ± 32 ...
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The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell …
J Li, L Kretzner - Mol Cell Biochem, 2003 - springerlink.com
... Jun Li and Leo Kretzner ... Nb remains unknown, but one of the best prognostic indicators
of Nb outcome is the status of the N-myc gene (also referred to as MYCN). ...
Cited by 2 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Soft tissue tumors: Rhabdomyosarcoma
C Morphological - caroll.vjf.cnrs.fr
... Davis RJ, D'Cruz CM, Lovell MA, Biegel JA, Barr FG. Cancer Res. 1994 Jun
1;54(11):2869-72. Medline 94243800. MYCN gene amplification in rhabdomyosarcoma. ...
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