Phosphorylation of Pax 2 by the c-Jun N-terminal Kinase and Enhanced Pax 2-dependent Transcription … - Full text - MIT Libraries
Y Cai, MS Lechner, D Nihalani, MJ Prindle, LB … - J Biol Chem, 2002 - jbc.org
... 277/2/1217 (most recent). M109663200v1. Phosphorylation of Pax2 by the c-Jun N-terminal
Kinase and Enhanced Pax2-dependent Transcription Activation *. ...
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Lmx 1 b controls the differentiation and migration of the superficial dorsal horn neurons of the … - Full text - MIT Libraries
YQ Ding, J Yin, A Kania, ZQ Zhao, RL Johnson, ZF … - Development, 2004 - paincenter.wustl.edu
... Yu-Qiang Ding 1, *, Jun Yin 1 , Artur Kania 2 , Zhong-Qiu Zhao 1 , Randy L ... For double
staining of LBX1 with BRN3A, PHOX2A with PAX2, and LMX1B and PHOX2A, Cy3 ...
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Mesenchymal to epithelial conversion in rat metanephros is induced by LIF - Full text - MIT Libraries
J Barasch, J Yang, CB Ware, T Taga, K Yoshida, H … - Cell, 1999 - ncbi.nlm.nih.gov
... leukemia inhibitory factor (LIF). LIF acted on epithelial precursors that
we identified by the expression of Pax2 and Wnt4. Other IL-6 ...
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… cloning in yeast: Identification of mammalian proteins that react with the leucine zipper of Jun - Full text - MIT Libraries
PM Chevray, D Nathans - Proc. Nat. Acad. Sci, 1992 - pnas.org
... ARTICLE. Protein Interaction Cloning in Yeast: Idetification of Mammalian Proteins
that React with the Leucine Zipper of Jun. PM Chevray and D Nathans. ...
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Embryonal hyperplasia of Bowman's capsular epithelium in patients with WT 1 mutations - Full text - MIT Libraries
R Fukuzawa, M Eccles, M Ikeda, J Hata - Pediatric Nephrology, 2003 - springerlink.com
... Thus, it is possi- ble that WT1 represses PAX2. ... ORIGINAL ARTICLE Ryuji Fukuzawa
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Angiotensin II stimulates Pax-2 in rat kidney proximal tubular cells: Impact on proliferation and … - Full text - MIT Libraries
SL Zhang, J Guo, B Moini, JR Ingelfinger - Kidney International, 2004 - blackwell-synergy.com
... Indeed, Cai Y et al [51] demonstrated that Pax2 is phosphorylated by the c-Jun
N-terminal kinase (JNK) to enhance Pax2-dependent transcription, but not the ERK1 ...
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Functional equivalency between Otx2 and Otx1 in development of the rostral head - Full text - MIT Libraries
Y Suda, J Nakabayashi, I Matsuo, S Aizawa - Development, 1999 - dev.biologists.org
... Yoko Suda 1, *, Jun Nakabayashi 1,2, *, Isao Matsuo 1 and Shinichi Aizawa 1 ... Wnt1
(McMahon and Bradley, 1990), En1 (Davis and Joyner, 1988), Pax2 (Dressler et al ...
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Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate … - Full text - MIT Libraries
Y Takagi, J Takahashi, H Saiki, A Morizane, T … - J Clin Invest, 2005 - jci.org
... Address correspondence to: Jun Takahashi, Department of Neurosurgery, Kyoto University
Graduate ... (F) RT-PCR for mesencephalic DA neuron markers Pax2, Ptx3, Nurr1 ...
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A series of no isthmus (noi) alleles of the zebrafish pax2. 1 gene reveals multiple signaling events … - Full text - MIT Libraries
K Lun, M Brand - Development, 1998 - dev.biologists.org
... Several transcription factors are required during development of the MHB, such as
En1 and En2 (Wurst et al., 1994; Millen et al., 1994), Pax2 (Torres et al ... pax2 ...
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Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic … - Full text - MIT Libraries
PD Brophy, L Ostrom, KM Lang, GR Dressler - Development, 2001 - dev.biologists.org
... Pax2, a new murine paired-box containing gene and its expression in the ... cell adhesion
in vitro, enhances metastatic behavior in vivo, and activates Jun kinase. ...
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Pax2 in development and renal disease
GR Dressler, AS Woolf - Int J Dev Biol, 1999 - ijdb.ehu.es
... The PAX2 transcription factor is expressed in cystic and hyperproliferative dysplastic
epithelia in ... XU, W., ROULD, MA, JUN, S., DESPLAN, C. and PABO, CO (1995 ...
Cited by 20 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - ijdb.ehu.es - Get it from MIT Libraries

PNAS Special Feature Home Help [Feedback][For Subscribers][Archive][Search][Contents] - Full text - MIT Libraries
… Kloter, S Flister, W Gehring, S Jun, C Desplan, B … - J. Biol. Chem, 2004 - pnas.org
... and RJ Davis JNK initiates a cytokine cascade that causes Pax2 expression and ... Home
page, Development Home page S Jun and C Desplan Cooperative interactions ...
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ONCOGENOMICS - Full text - MIT Libraries
GZ Shao, RL Zhou, QY Zhang, Y Zhang, JJ Liu, JA … - Oncogene, 2003 - nature.com
... Other attractive motifs are CREBP1/c-Jun, CEBP, PAX2/5/8, GATA, c-Ets-1,
E 2 F, LYF-1, and c/v-Myb binding sequences. Interestingly ...
Web Search

Homonucleotide expansion and contraction mutations of PAX2 and inclusion of Chiari 1 malformation as … - Full text - MIT Libraries
LA Schimmenti, HH Shim, JD Wirtschafter, VA … - Hum Mutat, 1999 - doi.wiley.com
... Coopera- tion of Pax2 and Pax5 in midbrain and cerebellum develop- ment. Proc Natl
Acad Sci USA 94:5703–5708. Xu W, Rould MA, Jun S, Desplan C, Pabo CO. ...
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Dynamic(re) organization of the podocyte actin cytoskeleton in the nephrotic syndrome - Full text - MIT Libraries
J Oh, J Reiser, P Mundel - Pediatric Nephrology, 2004 - springerlink.com
... Jun Oh · Jochen Reiser · Peter Mundel ... been identified which are specifically expressed
in developing and differentiated podocytes, including Pax2 [21], WT1 ...
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Possible role of Hes 5 for the rostrocaudal polarity formation of the tectum - Full text - MIT Libraries
J Kimura, T Katahira, I Araki, H Nakamura - Development Growth and Differentiation, 2004 - blackwell-synergy.com
... Jun Kimura, 1 + Tatsuya Katahira, 2 + Isato Araki 3 and Harukazu Nakamura 2 *. ... including
full-length ORF); ephrinA2 (Araki & Nakamura 1999); Pax2 (Okafuji et al ...
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Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms’ tumor - Full text - MIT Libraries
GR Dressler, EC Douglass - Proceedings of the National Academy of Sciences - pnas.org
... MJ Prindle, LB Holzman, and GR Dressler Phosphorylation of Pax2 by the c-Jun N-terminal
Kinase and Enhanced Pax2-dependent Transcription Activation J. Biol. ...
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Identification of a portable repression domain and an E1A-responsive activation domain in Pax4: a … - Full text - MIT Libraries
Y Fujitani, Y Kajimoto, T Yasuda, TA Matsuoka, H … - Mol Cell Biol, 1999 - mcb.asm.org
... Hideaki Kaneto, 1 Yutaka Umayahara, 1 Noriko Fujita, 1 Hirotaka Watada, 1 Jun-Ichi
Miyazaki ... acid at position 47, which is Asp in Pax6 but His in Pax2, Pax5, and ...
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c-Jun N-terminal kinase regulates lamellipodial protrusion and cell sheet migration during … - Full text - MIT Libraries
ZM Altan, G Fenteany - Biochem. Biophys. Res. Commun, 2004 - chem.uic.edu
c-Jun N-terminal kinase regulates lamellipodial protrusion and cell ... c-Jun N-terminal
kinase (JNK) is emerging as an important regulator of cell migration. ...
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Pax3 is required for enteric ganglia formation and functions with Sox10 to modulate expression of c- … - Full text - MIT Libraries
D Lang, F Chen, R Milewski, J Li, MM Lu, JA … - J. Clin. Invest, 2000 - jci.org
... Deborah Lang , Fabian Chen , Rita Milewski , Jun Li , Min Min Lu and Jonathan A ...
ß-galactosidase, and variable amounts of pCMV-Pax3 (42), pCMV-Pax2 (provided by ...
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Constitutively Active Cytoplasmic c-Jun N-Terminal Kinase 1 Is a Dominant Regulator of Dendritic … - Full text - MIT Libraries
B Bjoerkblom, N Oestman, V Hongisto, V Komarovski, … - The Journal of Neuroscience, 2005 - jneurosci.org
... Cellular/Molecular Constitutively Active Cytoplasmic c-Jun N-Terminal Kinase 1 Is
a Dominant Regulator of Dendritic Architecture: Role of Microtubule ...
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JNK initiates a cytokine cascade that causes Pax 2 expression and closure of the optic fissure - Full text - MIT Libraries
CR Weston, A Wong, JP Hall, ME Goad, RA Flavell, … - Genes & Development, 2003 - genesdev.org
... Sections were stained with the following antibodies: Phospho-c-Jun (Cell Signaling),
Pax2 (Zymed), Pax6 (Developmental Studies Hybridoma Bank), and antibodies ...
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The Proximal Tubule Phenotype and Its Disruption in Acute Renal Failure and Polycystic Kidney …
R Witzgall - Exp Nephrol, 1999 - content.karger.com
... structure, although it may not be suf- ficient – at the inductive phase, WT1, Pax2
and Emx2 are ... factors Egr-1 [18], ATF3 [19], c-Fos [9, 20] and c-Jun [19, 20 ...
Cited by 3 - Web Search - content.karger.com - biologie.uni-regensburg.de - ncbi.nlm.nih.gov - Get it from MIT Libraries

Groucho suppresses Pax 2 transactivation by inhibition of JNK-mediated phosphorylation - Full text - MIT Libraries
Y Cai, PD Brophy, I Levitan, S Stifani, GR … - The EMBO Journal, 2003 - embojournal.npgjournals.com
... Cai,Y., Lechner,MS, Nihalani,D., Prindle,MJ, Holzman,LB and Dressler,GR (2002)
Phosphorylation of Pax2 by the c-Jun N-terminal kinase and enhanced Pax2 ...
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Emx2 and Pax6 Function in Cooperation with Otx2 and Otx1 to Develop Caudal Forebrain Primordium That … - Full text - MIT Libraries
J Kimura, Y Suda, D Kurokawa, ZM Hossain, M … - The Journal of Neuroscience, 2005 - jneurosci.org
... Jun Kimura, 1 * Yoko Suda, 1 * Daisuke Kurokawa, 1 Zakir M. Hossain, 1 Miwa ... to this
sulcus, a series of transcriptional factors, Otx2, Gbx2, Pax2, En1, Pax6 ...
Web Search - jneurosci.org - ncbi.nlm.nih.gov

Missense mutation and hexanucleotide duplication in the PAX 2 gene in two unrelated families with … - Full text - MIT Libraries
K Devriendt, G Matthijs, B Van Damme, D Van … - Human Genetics, 1998 - springerlink.com
... coloboma syndrome in patients with extreme variability of pheno- type and identical
PAX2 mutations ... Am J Med Genet 29:597–605 Xu W, Rould MA, Jun S, Desplain C ...
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Autophagy: Many paths to the same end
AM Cuervo - Molecular and Cellular Biochemistry, 2004 - kluweronline.com
Page 1. MCBI ND-03-6554/5267739 March 16, 2004 12:8 TECHBOOKS UNCORRECTED
PR OOF Molecular and Cellular Biochemistry xxx: 1–18, 2004. ...
Cited by 3 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The Proximal Tubule Phenotype and Its Disruption in Acute Renal Failure and Polycystic Kidney …
E Nephrology - Experimental Nephrology, 1999 - content.karger.com
... certain structure, although it may not be sufficient - at the inductive phase, WT1,
Pax2 and Emx2 ... factors Egr-1 [18], ATF3 [19], c-Fos [9, 20] and c-Jun [19, 20 ...
Web Search - content.karger.com - dx.doi.org - karger.com

Expression of mitogen-activated protein kinases in human renal dysplasia - Full text - MIT Libraries
S Omori, R Fukuzawa, M Hida, M Awazu - Kidney International, 2002 - blackwell-synergy.com
... p38 MAPK (p38) are strongly expressed in the developing kidney, whereas c-Jun
N-terminal ... PAX2 and galectin-3, markers for this lineage, have been shown to be ...
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Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of … - Full text - MIT Libraries
J Hatakeyama, Y Bessho, K Katoh, S Ookawara, M … - Development, 2004 - w3dibit.hsr.it
... Jun Hatakeyama 1 , Yasumasa Bessho 1, *, Kazuo Katoh 2 , Shigeo Ookawara 2 ... However,
the downstream homeodomain genes Pax2, which specifies the optic stalk ...
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The Secreted Frizzled Related Protein 2(SFRP 2) Gene Is a Target of the Pax 2 Transcription Factor - Full text - MIT Libraries
PD Brophy, KM Lang, GR Dressler - J Biol Chem, 2003 - jbc.org
... Pax2 protein contains a DNA-binding domain, an octapeptide domain with repressor
activity, and a transactivation domain that can be phosphorylated by the c-Jun ...
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In vitro development of mouse embryonic stem cells lacking JSAP1 scaffold protein revealed its …
P Xu, K Yoshioka, D Yoshimura, Y Tominaga, T … - jbc.org
... The expression of components of c-Jun N-terminal kinase cascades and a subset ... the
embryonic ectoderm of E7.5 mouse embryo, while Wnt1 and Pax2 were coexpressed ...
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Pax genes and eye organogenesis
F Pichaud, C Desplan - Curr. Opin. Genet. Dev, 2002 - wwworm.biology.uh.edu
... Pax2 r rpe ... 5. Xu W, Rould MA, Jun S, Desplan C, Pabo CO: Crystal structure of a paired
domain-DNA complex at 2.5 Å resolution reveals structural basis for Pax ...
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TwoFrodo/Dapper homologs are expressed in the developing brain and mesoderm of zebrafish - Full text - MIT Libraries
M Gillhouse, M Wagner Nyholm, H Hikasa, SY Sokol, … - Developmental Dynamics, 2004 - doi.wiley.com
... distinct transduction pathways: the canonical ( -catenin) pathway and the c-Jun
N-terminal ... domain is adjacent to the optic stalk expression domain of pax2 (Fig ...
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Epithelial differentiation of metanephric mesenchymal cells after stimulation with hepatocyte growth … - Full text - MIT Libraries
SL Karp, A Ortiz-Arduan, S Li, EG Neilson - Proc Natl Acad Sci US A, 1994 - pubmedcentral.nih.gov
... One of our mesenchymal clones, MMR1, expresses little Pax2, uvomorulin, or cytokeratin
but does express neural ... J Histochem Cytochem 1983 Jun;31(6):840–842. ...
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Phosphorylation of the Transactivation Domain of Pax 6 by Extracellular Signal-regulated Kinase and … - Full text - MIT Libraries
I Mikkola, JA Bruun, G Bjoerkoey, T Holm, T … - J Biol Chem, 1999 - jbc.org
... Assays with c-Jun N-terminal kinase (JNK) was performed as described pre- viously
(52 ... In contrast to what has been found for the Pax2, -5, and -8 subfamily of ...
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PTIP, a novel BRCT domain-containing protein interacts with Pax 2 and is associated with active … - Full text - MIT Libraries
MS Lechner, I Levitan, GR Dressler - Nucleic Acids Research, 2000 - nar.oupjournals.org
... using antibodies against Pax2, PTIP or GAD (Santa Cruz Biotechnology, Santa Cruz,
CA) (data not shown). The positive control fusion proteins, fos/jun or full ...
Cited by 13 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Caspase inhibition reduces tubular apoptosis and proliferation and slows disease progression in … - Full text - MIT Libraries
Y Tao, J Kim, S Faubel, JC Wu, SA Falk, RW Schrier … - Proceedings of the National Academy of Sciences, 2005 - pnas.org
... Yunxia Tao * , Jun Kim * , Sarah Faubel * , Joe C. Wu , Sandor A. Falk * , Robert
W ... However, in cpk mice crossed with Pax2-deficient mice, reduced gene dosage ...
Web Search - dx.doi.org - pnas.org - ncbi.nlm.nih.gov

Transcriptional regulation by the MAP kinase signaling cascades - Full text - MIT Libraries
SH Yang, AD Sharrocks, AJ Whitmarsh - Gene, 2003 - www-unix.oit.umass.edu
... bZIP Fra1, MafA ERK 21, 22 c-Jun, JunB, JunD JNK 5, 23, 24 CHOP, ATF6 ... ERK 47–54 TCFh1,
NFAT4, NFATc1, Pax2, E2F1 JNK 55–59 STAT1, CDX2, NFATp, NFATc4, p73 ...
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Mouse models of congenital cataract
J Graw - Eye, 1999 - ncbi.nlm.nih.gov
Eye. 1999 Jun;13 ( Pt 3b):438-44. ... D19Mit10. Several candidate genes have
been excluded (Chuk1, Fgf8, Lbp1, Npm3, Pax2, Pitx3). The ...
Cited by 12 - Web Search - Get it from MIT Libraries

Midbrain dopaminergic neurons: determination of their developmental fate by transcription factors - Full text - MIT Libraries
HH Simon, L Bhatt, D Gherbassi, P Sgado, L Alberi - Ann NY Acad Sci, 2003 - ncbi.nlm.nih.gov
2003 Jun;991:36-47. ... of this part of the midbrain is probably determined by the
combinatorial expression of three transcription factors, Otx2, Pax2, and Pax5. ...
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In Vitro Development of Mouse Embryonic Stem Cells Lacking JNK/Stress-activated Protein Kinase- … - Full text - MIT Libraries
P Xu, K Yoshioka, D Yoshimura, Y Tominaga, T … - J Biol Chem, 2003 - jbc.org
... JSAP1 and c-Jun N-terminal kinase 3 were coexpressed in the embryonic ectoderm of
E7.5 mouse embryo, whereas Wnt1 and Pax2 were coexpressed with JSAP1 at the ...
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Origin of the paired domain - Full text - MIT Libraries
R Breitling, JK Gerber - Development Genes and Evolution, 2000 - springerlink.com
... Accession numbers are: human Pax1, P15863; mouse Pax2, P32114; quail Pax3, O13081;
human Pax6 ... Ann NY Acad Sci 785:27–33 Bertuccioli C, Fasano L, Jun S, Wang S ...
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Transcription factors in eye development: a gorgeous mosaic - Full text - MIT Libraries
J Kumar, K Moses - Genes Dev, 1997 - genesdev.org
... Pax2 contributes to inner ear patterning and optic nerve trajectory. ... JUN cooperates
with the ETS domain protein Pointed to induce photoreceptor R7 fate in the ...
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New aspects of Wnt signaling pathways in higher vertebrates
J Huelsken, W Birchmeier - Curr. Opin. Genet. Dev, 2001 - bret.mc.vanderbilt.edu
... cell polarity pathway (orange in Figure 1), Wnt signaling activates Jun-N-terminal ...
differentiation and expression of otic markers like Nkx5.1, Pax2, SOHo1 and ...
Cited by 145 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms’ … - Full text - MIT Libraries
A Poleev, H Fickenscher, S Mundlos, A Winterpacht, … - Development, 1992 - dev.biologists.org
... The truncated Pax8 protein becomes more similar to the predicted murine Pax2 protein,
that is also expressed during kidney development and lacks the ...
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Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish - Full text - MIT Libraries
F Carreira-Barbosa, ML Concha, M Takeuchi, N Ueno, … - Development, 2003 - dev.biologists.org
... Moreover, downstream of the small GTPases, the activation of Jun-N-terminal kinase
(JNK ... emx1 (Morita et al., 1995 ), rx3 (Chuang et al., 1999 ), pax2.1 (Krauss ...
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Transcription factors in dysmorphology - Full text - MIT Libraries
D Lacombe - Clinical Genetics, 1999 - blackwell-synergy.com
... PAX2 mutations have also been observed in renal hypoplasia either isolated or ... They
interact with transcription factors, such as TFIIB, Jun, Fos, Myb, E1A, E2F ...
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Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... AP1FJ CREB 188.9 HSF2 STAT 62.8 HNF1 SRF 31.0 CEBP NFAT 184.3 PAX2 PAX3 61.8
CDPCR3HD SRF 30.6 ... GATA-2 c-Jun GATA1_03 CREBP1CJUN_01 1.9 ...
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Axes establishment during eye morphogenesis in Xenopus by coordinate and antagonistic actions of BMP … - Full text - MIT Libraries
S Sasagawa, T Takabatake, Y Takabatake, T … - Genesis, 2002 - doi.wiley.com
... 3g, h) and pax2 (Fig. ... it has been reported that there are autoregulatory loops of
bmp4 that are mediated by vent2 (Schuler-Metz et al., 2000) or c-Jun (AP-1 ...
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