c-Jun interacts with the corepressor TG-interacting factor(TGIF) to suppress Smad 2 transcriptional … - Full text - MIT Libraries
M Pessah, C Prunier, J Marais, N Ferrand, A Mazars … - Proceedings of the National Academy of Sciences, 2001 - pnas.org
... c-Jun Binds TGIF. ... As shown in Fig. 4B, c-Jun bound specifically to GST-TGIF,
suggesting a direct interaction between c-Jun and TGIF. ...
Cited by 25 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

c-Jun Associates with the Oncoprotein Ski and Suppresses Smad 2 Transcriptional Activity - Full text - MIT Libraries
M Pessah, J Marais, C Prunier, N Ferrand, F … - J Biol Chem, 2002 - jbc.org
... Interaction of activated c-Jun with TGIF may prevent the recruitment of p300/CBP
to TGF- -activated Smad2, thus reducing the ability of the Smad complex to ...
Cited by 8 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

… Expression of novH in Adrenocortical Cells Is Down-regulated by TGFbeta 1 through c-Jun in a Smad- … - Full text - MIT Libraries
J Lafont, M Laurent, H Thibout, F Lallemand, Y Le … - J Biol Chem, 2002 - jbc.org
... It has also been reported that by reinforcing the association between c-Jun and
TGIF, TGF 1 leads to the repression of AP1-mediated transcriptional activity (41 ...
Cited by 5 - Web Search - jbc.org - ncbi.nlm.nih.gov

Smads bind directly to the Jun family of AP-1 transcription factors - Full text - MIT Libraries
NT Liberati, MB Datto, JP Frederick, X Shen, C … - Biochemistry, 1999 - dx.doi.org
... F. Lallemand, JM Gauthier, and A. Atfi c-Jun interacts with the corepressor
TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity PNAS, May ...
Cited by 160 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result … - Full text - MIT Libraries
J Shen, CA Walsh - Mol Cell Biol, 2005 - pubmedcentral.nih.gov
... Targeted Disruption of Tgif, the Mouse Ortholog of a Human Holoprosencephaly Gene,
Does Not Result in Holoprosencephaly in Mice †. Jun Shen and Christopher A ...
Web Search - ncbi.nlm.nih.gov

Targeted Disruption of Tgif, the Mouse Ortholog of a Human Holoprosencephaly Gene, Does Not Result …
J Shen, CA Walsh - mcb.asm.org
... Targeted Disruption of Tgif, the Mouse Ortholog of a Human Holoprosencephaly Gene,
Does Not Result in Holoprosencephaly in Mice {dagger}. Jun Shen and ...
Web Search - mcb.asm.org

c-Jun associates with the oncoprotein Ski and suppresses Smad2
M Pessah, J Marais, C Prunier, N Ferrand, F … - jbc.org
... Interaction of activated c- Jun with TGIF may prevent the recruitment of p300/CBP
to TGF-β-activated Smad2, thus reducing ... 16 ARE-Lux+FAST1 TGIF c- Jun Ski 0 2 ...
Web Search

Research Article Suppression of TGF-b signaling by conophylline via upregulation of c-Jun expression
S Atsumi, A Nagasawa, T Koyano, T Kowithayakornd, … - springerlink.com
... Key words. TGF-b; c-Jun; TGIF; Smad; conophylline; p300; FAST; Mv1Lu. ... c-Jun has been
prosposed to enhance the association of Smad2 with TGIF [23]. ...
Web Search

TGIF 反义寡核苷酸对胃癌细胞增生和凋亡的影响
T Effectsof - wjgnet.com
... ＴＧＩＦ 的半衰期延长ＴＧＩＦ 蛋白浓度升高 ［１４］ ；
且ｃ－Ｊｕｎ 能增强ＴＧＩＦ 与ｓｍａｄ２ 的结合 ［１５ ...
View as HTML - Web Search - wjgnet.com - wjgnet.com - wjgnet.com

Suppression of TGF-beta signaling by conophylline via upregulation of c-Jun expression. - Full text - MIT Libraries
S Atsumi, A Nagasawa, T Koyano, T Kowithayakornd, … - Cell Mol Life Sci, 2003 - ncbi.nlm.nih.gov
... Instead, we found that conophylline increased the expression of c-Jun, which had
been earlier shown to interact with the corepressor TGIF to suppress the ...
Web Search - ncbi.nlm.nih.gov

The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell … - Full text - MIT Libraries
L Grotewold, U Ruther - The EMBO Journal, 2002 - embojournal.npgjournals.com
... A., Lallemand,F., Gauthier,JM and Atfi,A. (2001) c-Jun interacts with the corepressor
TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity. ...
Cited by 43 - Web Search - nature.com - emboj.org - tagc.univ-mrs.fr - all 9 versions »

c-Jun Inhibits Transforming Growth Factor beta-mediated Transcription by Repressing Smad 3 … - Full text - MIT Libraries
S Dennler, C Prunier, N Ferrand, JM Gauthier, A … - J Biol Chem, 2000 - jbc.org
... depends on co-activators such as CBP/p300 and co-repressors such as TGIF, Ski, or ...
Since c-Jun also interacts with CBP/p300, c-Jun may modify the interaction of ...
Cited by 32 - Web Search - jbc.org - ncbi.nlm.nih.gov

Tgif and Smad2 mutations increase mammalian sensitivity to retinoic acid teratogenesis
S Lasse - 2005 - kb.osu.edu
Title: Tgif and Smad2 mutations increase mammalian sensitivity to retinoic acid
teratogenesis. Authors: Lasse, Samuel. ... Issue Date: Jun-2005. ...
Cached - Web Search - kb.osu.edu

Calcium Regulates Transcriptional Repression of Myocyte Enhancer Factor 2 by Histone Deacetylase 4 - Full text - MIT Libraries
HD Youn, CM Grozinger, JO Liu - J Biol Chem, 2000 - jbc.org
... the activation of the minimal MEF2-responsive element of the c-Jun promoter and ... Unlike
Cabin1 but similar to MITR, both Rb and TGIF directly recruit HDAC1/2 (38 ...
Cited by 54 - Web Search - jbc.org - plaza.snu.ac.kr - ncbi.nlm.nih.gov - all 5 versions »

The novel E 3 ubiquitin ligase Tiul 1 associates with TGIF to target Smad 2 for degradation - Full text - MIT Libraries
SR Seo, F Lallemand, N Ferrand, M Pessah, S L' … - The EMBO Journal, 2004 - embojournal.npgjournals.com
... Prunier C, Marais J, Ferrand N, Mazars A, Lallemand F, Gauthier JM, Atfi A (2001)
c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress ...
Cited by 3 - Web Search - nature.com - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Tgif and Smad2 mutations increase mammalian sensitivity to retinoic acid teratogenesis
ASH Thesis, S Lasse, M Weinstein, S Cole, C … - kb.osu.edu
... gene transcription (reviewed in [18]). However, other mediators such as Tgif,
Ski, and c-Jun [19-21] can recruit histone deacetylases ...
View as HTML - Web Search

… {alpha} 2 Type I Collagen Gene (COL1A2) Expression in Human Fibroblasts via c-Jun NH 2-Terminal … - Full text - MIT Libraries
J Wendling, A Marchand, A Mauviel, F Verrecchia - Mol Pharmacol, 2003 - molpharm.aspetjournals.org
... the proto-oncogenes c-Ski and SnoN (Akiyoshi et al., 1999 ), TGIF (Wotton et al ... On
the other hand, induction of Jun proteins by cytokines have been shown to ...
Cited by 3 - Web Search - molpharm.aspetjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Regulation of transforming growth factor-ß and bone morphogenetic protein signalling by … - Full text - MIT Libraries
K Kahata, M Hayashi, M Asaka, U Hellman, H … - Genes to Cells, 2004 - genestocellsonline.org
... 1 ,3 , Masahiro Asaka 2 , Ulf Hellman 4 , Hirochika Kitagawa 5 , Jun Yanagisawa
5 ... Other proteins involved in Smad regulation include c-Ski, SnoN and TGIF. ...
Cited by 1 - Web Search - blackwell-synergy.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

… Activated by Transforming Growth Factor-beta through Cooperativity of Smads and c-Jun/c-Fos Proteins - Full text - MIT Libraries
CL Liang, JL Chen, YPP Hsu, JT Ou, YS Chang - J Biol Chem, 2002 - jbc.org
... M107420200v1. Epstein-Barr Virus BZLF1 Gene Is Activated by Transforming Growth
Factor- through Cooperativity of Smads and c-Jun/c-Fos Proteins *. ...
Cited by 2 - Web Search - jbc.org - ncbi.nlm.nih.gov

Jun proteins modulate the ovary-specific promoter of aromatase gene in ovarian granulosa cells via a … - Full text - MIT Libraries
S Ghosh, Y Wu, R Li, Y Hu - Oncogene, 2005 - nature.com
... to the CLS site and utilize the N-terminal domain of Jun to either ... Smad2-mediated
transcription activation by recruiting the nuclear co- repressor TGIF via the ...
Web Search - nature.com - ncbi.nlm.nih.gov

AP-1 as a regulator of cell life and death - Full text - MIT Libraries
E Shaulian, M Karin - Nature Cell Biology, 2002 - nature.com
... Pessah, M. et al. c-Jun interacts with the corepressor TG-interacting factor (TGIF)
to suppress Smad2 transcriptional activity. Proc. Natl Acad. Sci. ...
Cited by 210 - Web Search - nature.com - ncbi.nlm.nih.gov

Middle Interhemispheric Variant of Holoprosencephaly Associated with Diffuse Polymicrogyria - Full text - MIT Libraries
J Takanashi, AJ Barkovich, NJ Clegg, MR Delgado - American Journal of Neuroradiology, 2003 - ajnr.org
... Address reprint requests to Jun-ichi Takanashi, MD, Department of Pediatrics, Graduate
School of ... to HPE, namely, SHH in HPE3, SIX3 in HPE2, and TGIF in HPE4 (10 ...
Cited by 2 - Web Search - ajnr.org - ajnr.org - ncbi.nlm.nih.gov

Oligo GEArray® Human TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... CDKN2B, COL1A1, COL1A2, COL3A1, FOS, GSC, IGF1, IGFBP3, IL6, ITGB5, ITGB7, IVL,
JUN, JUNB, MYC, PDGFB, SERPINE1, TGFB1I1, TGFB1I4, TGFBI, TGIF, TIMP1 BMP ...
View as HTML - Web Search

Oligo GEArray® Mouse TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... Cdkn2b, Col1a1, Col1a2, Col3a1, Fos, Gsc, Igf1, Igfbp3, Il6, Itgb7, Ivl, Jun, Junb,
Myc, Pdgfb, Plat, Plau, Serpine1, Tgfb1i1, Tgfb1i4, Tgfbi, Tgif, Timp1 BMP ...
View as HTML - Web Search

Role of transforming growth factor beta in cancer - Full text - MIT Libraries
B Pasche - Journal of Cellular Physiology, 2001 - doi.wiley.com
... JNK and p38, which in turn regulate the activity of Fos, Jun, ATF-2 and ... TGIF is a
homeo-domain protein that represses Smad dependent transcription (Wotton et al ...
Cited by 63 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Effects of transforming growth interacting factor on biological behaviors of gastric carcinoma cells - Full text - MIT Libraries
ZL Hu, JF Wen, DS Xiao, H Zhen, CY Fu - World J Gastroenterol, 2005 - wjgnet.com
... N, Mazars A, Lallemand F, Gauthier JM, Atfi A. c-Jun interacts with the corepressor
TG- interacting factor (TGIF) to suppress Smad2 transcriptional activity. ...
View as HTML - Web Search - wjgnet.com - wjgnet.com - ncbi.nlm.nih.gov - all 5 versions »

Smad6 Is a Smad1/5-induced Smad Inhibitor - Full text - MIT Libraries
W Ishida, T Hamamoto, K Kusanagi, K Yagi, M … - J Biol Chem, 2000 - jbc.org
... with various transcription factors, including FAST1 (14), c-Jun-c-Fos ... core histones
(2). Under certain conditions, transcriptional corepressors, eg TGIF and c ...
Cited by 88 - Web Search - jbc.org - ncbi.nlm.nih.gov

Transcription activator protein 1 (AP-1) mediates D-but not E-adrenergic hypertrophic growth …
G Taimor, KD Schlueter, P Best, S Helmig, HM Piper - intl-ajpheart.physiology.org
... JM, and Atfi A. c-Jun interacts with the corepressor TG-interacting factor
(TGIF) to suppress Smad2 transcriptional activity. Proc ...
Web Search

HOW CELLS READ TGF-< img border='0' src='/__chars/beta/black/med/base/glyph. gif' align='middle' alt … - Full text - MIT Libraries
J Massague - Nature Reviews Molecular Cell Biology - nature.com
1. Massagué, J. TGF signal transduction. Annu. Rev. Biochem. 67, 753-791
(1998). | Article | PubMed | ISI | ChemPort |. 2. Schier ...
Cited by 68 - Web Search

Signaling inputs converge on nuclear effectors in TGF-b signaling - Full text - MIT Libraries
P ten Dijke, K Miyazono, CH Heldin - Trends Biochem. Sci, 2000 - chemistry.montana.edu
... Hox, homeobox gene; JNK, c-Jun N-terminal kinase, SIP1, Smad-interacting protein
1; Ski/SnoN, Sloan- Kettering avian retrovirus/ski-related gene; TGIF, 5’TG3 ...
Cited by 177 - View as HTML - Web Search - mcb.berkeley.edu - ingentaconnect.com - all 4 versions »

RECEPTOR-REGULATED SMADS IN TGF-ß SIGNALING
F Liu - Frontiers in Bioscience, 2003 - bioscience.org
... 95-97, 112. c-fos. activate c-jun and collagenase promoters. Smad3(MH2). 95.
FAST-1. ... recruit HDAC. TGIF. Homeo-domain factor; recruit HDAC, mSin3A, CtBP. Smad2, ...
Cited by 1 - Cached - Web Search - bioscience.org - bioscience.org - bioscience.org

GEArray Q Series Human TGFβ BMP Signaling Pathway Gene Array Cat. No.* Kit Size HS-023-2/HS-023N-2 …
FG Grouping - tebu-bio.com
... ITGB5 (integrin b5), ITGB7 (integrin b7), IVL (involucrin), JUN, JUNB, MYC, Goosecoid,
PDGFB, SERPINE1 (PAI-1), SNC73 (IgA), TGFB1I1, TGFBI, TGIF, TIMP1, TSC22 ...
View as HTML - Web Search

GEArray Q Series Mouse TGFβ BMP Signaling Pathway Gene Array Cat. No.* Kit Size MM-023-2/MM-023N-2 …
FG Grouping - tebu-bio.com
... Itgb5 (integrin b5), Itgb7 (integrin b7), Ivl (involucrin), Jun, Junb, Pdgfb, Plat
(tPa), Plau (uPA), Serpine1 (PAI-1), Tgfb1i1, Tgfbi, Tgif, Timp, Tgfb1i4 ...
View as HTML - Web Search

Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice - Full text - MIT Libraries
T Hide, J Hatakeyama, C Kimura-Yoshida, E Tian, N … - Development, 2002 - dev.biologists.org
... Takuichiro Hide 1 ,2 , Jun Hatakeyama 1 , Chiharu Kimura-Yoshida 1 ,3 , E Tian 1 ...
have been identified recently, including SHH, ZIC2, SIX3, TGIF and HESX1 ...
Cited by 7 - Web Search - cdb.riken.go.jp - cdb.riken.jp - ncbi.nlm.nih.gov - all 6 versions »

How cells read TGF-beta signals - Full text - MIT Libraries
J Massague - Nat Rev Mol Cell Biol, 2000 - nature.com
... Thrombospondin Activin SHH SHH BMP LEF1/TCF CBFA1 CBFA3 Mixer STAT3 JUN Wnt BMP
TGF-β Xnr LIF TNF-α ... Ski/SnoN Corepressors TGIF Signalling receptors ...
Cited by 286 - Web Search - bio.kaist.ac.kr - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The Ski-binding Protein C 184 M Negatively Regulates Tumor Growth Factor-{beta} Signaling by … - Full text - MIT Libraries
K Kokura, H Kim, T Shinagawa, MM Khan, T Nomura, S … - J Biol Chem, 2003 - jbc.org
... are transmitted to transcriptional regulators, such as ATF-2 and c-Jun (AP-1 ... and
Smad3 in the nucleus bind to transcriptional corepressors such as TGIF (11) and ...
Cited by 3 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Transcription activator protein 1 mediates {alpha}-but not {beta}-adrenergic hypertrophic growth … - Full text - MIT Libraries
G Taimor, KD Schluter, P Best, S Helmig, HM Piper - Am J Physiol Heart Circ Physiol, 2004 - intl-ajpheart.physiology.org
... Mazars A, Lallemand F, Gauthier JM, and Atfi A. c-Jun interacts with the corepressor
TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity. ...
Cited by 1 - Web Search - intl-ajpheart.physiology.org - ncbi.nlm.nih.gov

The Ski-binding Protein C184M Negatively Regulates Tumor Growth Factor-Signaling by Sequestering the …
K Kokura, H Kim, T Shinagawa, MM Khan, T Nomura, S … - jbc.org
... are transmitted to transcriptional regulators, such as ATF-2 and c-Jun (AP-1 ... Smad3
in the nucleus bind to transcriptional co- repressors such as TGIF (11) and ...
Web Search - sjs.ntu.edu.cn

An Essential Role for Mad Homology Domain 1 in the Association of Smad 3 with Histone Deacetylase … - Full text - MIT Libraries
NT Liberati, M Moniwa, AJ Borton, JR Davie, XF … - J Biol Chem, 2001 - jbc.org
... C, in vitro binding experiments of GST-Smad3 and GST-Smad3 mutants with in vitro
TNT-c-ski, TNT-SnoN, TNT-TGIF, TNT-Sin3A, and TNT-c-Jun. ...
Cited by 14 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

The role of TGF-β in digestive organ disease - Full text - MIT Libraries
S Takenoshita, T Fukushima, K Kumamoto, M Iwadate - Journal of Gastroenterology, 2002 - springerlink.com
... scription by cooperating with β-catenin, TCF/LEF, Runx, c-jun, FAST, and ... Alternatively,
they are connected with corepressors, such as TGIF, c-Ski, and SnoN ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor beta … - Full text - MIT Libraries
M KAWABATA, T IMAMURA, H INOUE, JI HANAI, A … - J. Immunol, 2004 - dx.doi.org
... F. Lallemand, JM Gauthier, and A. Atfi c-Jun interacts with the corepressor
TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity PNAS, May ...
Web Search - dx.doi.org - pnas.org - pnas.org

GEArray Q Series Mouse TGFβ BMP Signaling Pathway Gene Array: AR-SAMM-023
FG Grouping - eurogentec.be
... Itgb5 (integrin b5), Itgb7 (integrin b7), Ivl (involucrin), Jun, Junb, Pdgfb, Plat
(tPa), Plau (uPA), Serpine1 (PAI-1), Tgfb1i1, Tgfbi, Tgif, Timp, Tgfb1i4 ...
View as HTML - Web Search - eurogentec.com

GEArray Q Series Human TGFβ BMP Signaling Pathway Gene Array: AR-SAHS-023
FG Grouping - eurogentec.com
... ITGB5 (integrin b5), ITGB7 (integrin b7), IVL (involucrin), JUN, JUNB, MYC, Goosecoid,
PDGFB, SERPINE1 (PAI-1), SNC73 (IgA), TGFB1I1, TGFBI, TGIF, TIMP1, TSC22 ...
View as HTML - Web Search - eurogentec.be

Prep 1, a novel functional partner of Pbx proteins - Full text - MIT Libraries
J Berthelsen, V Zappavigna, F Mavilio, F Blasi - The EMBO Journal, 1998 - embojournal.npgjournals.com
... Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, IROQUIS, TGIF) reveals
a ... P. , Nerlov, C. and Verde, P. (1995) Heterodimerization of c-Jun with ATF ...
Cited by 66 - Web Search - emboj.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov - all 6 versions »

Regulation of cell proliferation by Smad proteins - Full text - MIT Libraries
P Ten Dijke, MJ Goumans, F Itoh, S Itoh - Journal of Cellular Physiology, 2002 - doi.wiley.com
... the proteasome (Saha et al., 2001) and to induce an increase in TGIF expression
level ... et al., 1998; Liberati et al., 1999: Qing et al., 2000), c-Jun as well as ...
Cited by 87 - Web Search - ncbi.nlm.nih.gov

Stat1-dependent and-independent pathways in IFN-γ-dependent signaling - Full text - MIT Libraries
CV Ramana, M Gil, RD Schreiber, GR Stark - J. Immunol - chosun.ac.kr
... and activator of transcription; TDAG-51, proline–glutamine–histidine-rich protein;
TGIF, 5′-TG ... EGR-1 and EGR-2; leucine-zipper factors, such as c-Jun and G ...
Cited by 75 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of … - Full text - MIT Libraries
VK Rajasekhar, A Viale, ND Socci, M Wiedmann, X Hu … - Mol. Cell, 2003 - microarray1.princeton.edu
... expected to be inherent for a cell at a given cellular related genes such
as Jun, Fos-like antigen, Id4, TGIF, condition. Comparison ...
Cited by 48 - View as HTML - Web Search - microbio.uab.edu - med.nyu.edu - all 7 versions »

Positive and negative regulation of TGF-beta signaling - Full text - MIT Libraries
K Miyazono - J Cell Sci, 2000 - jcs.biologists.org
... Smad3 and Smad4 then act in concert with c-Jun and ATF-2 in ... A homeodomain protein
of the TALE class, TGIF, is the first transcriptional co- repressor shown to ...
Cited by 90 - Web Search - jcs.biologists.org - ncbi.nlm.nih.gov - issoonline.com

NEW EMBO MEMBER'S REVIEW Transcriptional control by the TGF-b/Smad signaling system - Full text - MIT Libraries
J MassagueA, D Wotton - The EMBO Journal, 2000 - emboj.org
... Erk, JNK and p38, which in turn regulate the activity of Fos, Jun and ATF-2 ... TGIF
ASmad complex bound to DNAhas the option to recruit not only coactivators but ...
Cited by 107 - Web Search - nature.com

Critical Review
M Karin, E Shaulian - Life, 2001 - dx.doi.org
... long to the Jun (c-Jun, JunB, JunD), Fos (FosB, Fra-1 and Fra2), Maf(cMaf, MafB,
MafA, MafG/F/K, and Nrl), and ATF (ATF2, LRF1/ATF3, B-ATF, JDP1, JDP2 ...
Web Search - Get it from MIT Libraries