LMO2 and MEIS1 - Google Scholar

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization - Full text - MIT Libraries
BB Zeisig, T Milne, MP Garcia-Cuellar, S Schreiner … - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... most importantly Hoxa9 and Meis1 strongly cooperate to induce myeloid leukemias
in mice (6). Two other genes implicated in malignant transformation, Lmo2 and N ...
Cited by 12 - Web Search - dx.doi.org - mcb.asm.org - ncbi.nlm.nih.gov - all 6 versions »

MLL, Hox genes, and leukemia: the plot thickens - Full text - MIT Libraries
JL Hess - Blood, 2004 - bloodjournal.org
... a number of putative oncogenes outside the Hox genes, such as Lmo2, Flt3, and N ... multiple
Hox genes (including Hoxa5, Hoxa7, Hoxa9, Hoxa10, and Meis1 among others ...
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Progress in Hematology
Y Hayashi - cardenjennings.metapress.com
... reported on genes whose expression pattern distinguishes t(4;11)-ALLs from other
ALLs, including overexpressed oncogene [HOXA9, MEIS1, HOXA10, LMO2(RMBT2), MYC ...
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Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements - Full text - MIT Libraries
T Rozovskaia, O Ravid-Amir, S Tillib, G Getz, E … - Proceedings of the National Academy of Sciences, 2003 - pnas.org
... This includes activation of oncogenes (MYC, HOX A9 and MEIS1, LMO2, etc.), inactivation
of tumor suppressor genes such as FHIT and DAPK1, suppression of ...
Cited by 23 - Web Search - 171.66.122.165 - santafe.edu - weizmann.ac.il - all 10 versions »

Retroviral insertional mutagenesis identifies oncogene cooperation. - Full text - MIT Libraries
T Nakamura - Cancer Science, 2005 - blackwell-synergy.com
... The NUP98-HOXA9 expressing retrovirus was inserted 6 kb upstream of Meis1 in two ...
T-ALL, and integrations of the chain-bearing retrovirus in the LMO2 locus were ...
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Original Research Report
T TSANG, DT HARRIS - dx.doi.org
... Cell growth and maintenance INHBC AI239905 Inhibin, beta C LMO2 AA464544 LIM domain
only ... activity HOXA9 AA496921 Homeo box A9 HOXB2 AA911661 Homeo box B2 MEIS1
Web Search - liebertonline.com - liebertonline.com

Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the … - Full text - MIT Libraries
UR Kees, J Ford, M Watson, A Murch, M Ringner, RL … - Molecular Cancer Therapeutics, 2003 - thep.lu.se
... Simi- larly, high LMO2 expression was recorded for PER-550 cells, both by ... MEIS1
expression was reported to be exclusive to leukemia cells containing MLL ...
Cited by 3 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Design Principle of Gene Expression Used by Human Stem Cells; Implication for Pluripotency
R Title - arxiv.org
... The common genes include CD34, AC133, BMI1, TIE, HOXA10, FZD6, SOX4, TCF3, RUNX1,
FLT3, LMO2, SCA1, MEIS1, MPL, TEK, SCA1, MDR1 and others. Theses genes ...
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E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause … - Full text - MIT Libraries
DB Sykes, MP Kamps - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development
and potentiates ... Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in ...
Cited by 4 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Genetic programs regulating HSC specification, maintenance and expansion - Full text - MIT Libraries
J Lessard, A Faubert, G Sauvageau - Oncogene, 2004 - nature.com
... Lmo2 Embryonic lethality, absence of primitive erythropoiesis, presence of YS ... Meis1
Embryonic lethality, absence of megakaryocytes, reduced fetal liver CFCs ...
Web Search - ncbi.nlm.nih.gov

NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that … - Full text - MIT Libraries
YW Lin, C Slape, Z Zhang, PD Aplan - Blood, 2005 - bloodjournal.org
... Semiquantitative RT-PCR assay for Meis1. ... A large number of genes typically expressed
in erythroid precursors (LMO2, Eraf, HbbY, EpoR, and glycophorin A) were ...
Cited by 1 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Supplementary Data ‘Stemness’: Transcriptional Profiling of Embryonic and Adult Stem Cells
M Ramalho-Santos, S Yoon, Y Matsuzaki, RC Mulligan … - intl.sciencemag.org
... cycle/oncogenesis (70) eg Mapk 12/14, Mapkk3, K-Ras2, H-Ras, RhoB, All1, Fos, FosB,
Jun, JunB, Myc, N-Myc, Elf1, Ext2, Meis1, PU.1, Tal1 (Scl), Lmo2, Yes, ski ...
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Progress in Hematology
M Eguchi, M Eguchi-Ishimae, M Greaves - Int J Hematol, 2005 - cardenjennings.metapress.com
... HoxA9 and other Hox proteins in which the Hox cofactor Meis1 can accelerate ... Cre-Lox
recombination, is introduced into the genomic locus of LMO2, the expression ...
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HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL … - Full text - MIT Libraries
J Soulier, E Clappier, JM Cayuela, A Regnault, M … - Blood, 2005 - bloodjournal.org
... helix-loop-helix proteins (TAL1/SCL, TAL2, LYL1), homeodomain-containing proteins
(TLX1/HOX11, TLX3/HOX11L2), and LIM only proteins (LMO1, LMO2), which are ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

The Kinetic Status of Hematopoietic Stem Cell Subpopulations Underlies a Differential Expression of … - Full text - MIT Libraries
R Manfredini, R Zini, S Salati, M Siena, E … - Stem Cells, 2005 - stemcells.alphamedpress.org
... Among them, HOXA5, HOXA9, HOXA10, HOXB2, HOXB5, Meis1, and PBX2 are preferentially
expressed by ... key factors for HSC self-renewal [29, 30], and LMO2, CBFß, and ...
Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov

[CITATION] Acute Lymphoblastic Leukemia
MG Alterations
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Molecular Cytogenetics A new recurrent inversion, inv (7)(p15q34), leads to transcriptional …
F Speleman, B Cauwelier, N Dastugue, J Cools, B … - Leukemia, 2005 - nature.com
... levels of a subset of HOX genes (HOXA9, HOXA10, HOXC6 and MEIS1) in MLL ... expression
of certain T-cell oncogenes (HOX11, LYL1, TAL1, LMO1 and LMO2) in the ...
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A new recurrent inversion, inv (7)(p15q34), leads to transcriptional activation of
F Speleman, B Cauwelier, N Dastugue, J Cools, B … - Leukemia, 2005 - nature.com
... 3 Similarly, other T-cell leukemia specific genes (HOX11, LYL1, LMO1, LMO2, HOX11L2),
initially identified through rare chromosomal rearrangements involving ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... 27 The LMO2 Master Gene; Its Role as a Transcription Regulator Determining
Cell Fate in Leukemogenesis and in Hematopoiesis 483 ...
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Early steps in the evolution of multicellularity: deep structural and functional homologies among … - Full text - MIT Libraries
CC Coutinho, RN Fonseca, JJC Mansure, R Borojevic - Mechanisms of Development, 2003 - faculty.virginia.edu
... The identified promoter elements are putative binding sites for transcrip- tion
factors of the following families: TCF-1, CAAT binding protein, LMO2, USF-1 and ...
Cited by 4 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

The ubiquitous MLL gene and its multitude of chromosomal abnormalities - Full text - MIT Libraries
A Daser, TH Rabbitts - GENES & DEVELOPMENT, 2004 - dx.doi.org
... All MLL-associated leukemia subtypes had HOXA9 and MEIS1 expression (Armstrong et ...
expressed in stem cells and early progenitors from the Lmo2 promoter (Warren ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Luciferase Reporters: Less is More
A Paguio, B Almond, F Fan, P Stecha, D Garvin, M … - promega.com
... VIS1 HEN1 VIS1 GABP COMP1 WHP Pbx1/Meis1 AD-b Pit1 CREB CREB CREB CREB CREB CREB
CDE/CHR RAR PAR PAR PAR Lmo2 SRF Cut-like Cut-like Cut-like Cut-like Cut-like ...
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Global Analysis of RAR-Responsive Genes in the Xenopus Neurula Using cDNA Microarrays - Full text - MIT Libraries
K Arima, J Shiotsugu, R Niu, R Khandpur, M … - DEVELOPMENTAL DYNAMICS, 2005 - doi.wiley.com
Page 1. PATTERNS & PHENOTYPES Global Analysis of RAR-Responsive Genes in
the Xenopus Neurula Using cDNA Microarrays Kayo Arima, 1 ...
Cited by 1 - Web Search - blumberg-serv.bio.uci.edu - ncbi.nlm.nih.gov

PAINT: A Promoter Analysis and Interaction Network Generation Tool for Gene Regulatory Network …
R Vadigepalli, P Chakravarthula, DE Zak, JS … - Omics A Journal of Integrative Biology, 2003 - dx.doi.org
... V$MEF2/MMEF2.01 0.063316 0.28358 0.07989 V$MEIS/MEIS1.01 0.24903 0.64725 0.055006
V$MYOD/LMO2COM.01 0.16547 0.57736 0.041649 V$OCT1/OCT.01 0.46994 — 0.084003 ...
Cited by 4 - Web Search - liebertonline.com - che.udel.edu - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

pGL3 Luciferase Reporter Vectors
I Description, IIIP Components, IVC Methods, I … - promega.com
... VIS1 HEN1 VIS1 GABP COMP1 WHP Pbx1/Meis1 AD-b Pit1 CREB CREB CREB CREB CREB CREB
CDE/CHR RAR PAR PAR PAR Lmo2 SRF Cut-like Cut-like Cut-like Cut-like Cut-like ...
Web Search - genomics.sbg.ac.at - sci.sdsu.edu - shpromega.cn - all 8 versions »

I. I ntroduction
IV References - promega.com
... Pax1 FOXF2 MIBP1 GLI-k TCF/LEF-1 Pax-6 TALE VIS1 HEN1 VIS1 GABP COMP1 WHP Pbx1/Meis1
AD-b Pit1 CREB CREB CREB CREB CREB CREB CDE/CHR RAR PAR PAR PAR Lmo2
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Gene expression profiling and its application in studies of haematological malignancy - Full text - MIT Libraries
M Hubank - British Journal of Haematology, 2004 - blackwell-synergy.com
... et al (2002) applied hierarchical clustering to T-ALL tumours and showed clustering
of tumours associated with dysregulation of HOX11, TAL1, LYL1, LMO1 and LMO2 ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Current World Literature; Bibliography
T Blake, N Adya, CH Kim… - Current Opinion in Hematology, 2001 - co-hematology.com
... Leukemia 2000, 14:1885-1891. Davenport J, Neale GAM, Goorha R: Identification
of genes potentially involved in LMO2-induced leukemogenesis. ...
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[BOOK] Cytogenetic and molecular genetic changes in childhood acute leukaemias
T Niini - 2002 - ethesis.helsinki.fi
... t(11;14)(p15;q11) LMO1 Relocation to TCRδ TF <1 T t(11;14)(p13;q11) LMO2 Relocation
to TCRδ TF <1 T ... t(7;11)(q34;p13) LMO2 Relocation to TCRβ TF <1 T ...
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