Acute Lymphoblastic Leukemia in the Adult
C Translocations - Hematology, 1999 - hematology.org
... Although SCL/tal, LMO1, and LMO2 are either not expressed or expressed at very low
levels in ... (22) Individuals with neurofibro- matosis type I (NF1) have a ...
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CCAAT-binding factor regulates expression of the beta1 subunit of soluble guanylyl cyclase gene in … - Full text - MIT Libraries
IG Sharina, E Martin, A Thomas, KL Uray, F Murad - Proc Natl Acad Sci USA, 2003 - intl.pnas.org
... against CBF-A (CAAT and polyA probes), GFI1, and NF1 (GFI1 and ... factors involved in
hematopoietic development and differentiation, such as GATA1, LMO2, IK2 (20 ...
Cited by 4 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Basal transcriptional regulation of human damage-specific DNA-binding protein genes DDB 1 and DDB 2 … - Full text - MIT Libraries
AF Nichols, T Itoh, F Zolezzi, S Hutsell, S Linn - Nucleic Acids Research, 2003 - nar.oupjournals.org
... 1). Mutation of a potential NF1 site (–104 to –92) produced a moderate ... Although the
TRANSFAC search found a potential Lmo2 element in both mouse and human ...
Cited by 3 - Web Search - pubmedcentral.nih.gov - nar.oxfordjournals.org - ehscenter.berkeley.edu - all 8 versions »

Expression of Galectin-3 in Skeletal Tissues Is Controlled by Runx 2 - Full text - MIT Libraries
M Stock, H Schaefer, S Stricker, G Gross, S … - J Biol Chem, 2003 - jbc.org
... binding sites for AP1, AP4, C/EBP , CDP CR, c-Ets, CP2, c-Rel, GATA proteins, GFI1,
HNF3b, Ikaros factors, Lmo2 complex, MyoD, MZF1, NF1, NF-AT, NF- B, NFY, Nkx ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov

Annual Report 2002-2003
FP Board - 2003 - crg.es
Page 1. Annual Report 2002-2003 SCIENTIFIC BOARD Page 2. CENTRE DE REGULACIÓ GENÒMICA
Annual Report 2002-2003 SCIENTIFIC BOARD Design by Estudi Freixes ...
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Testing of new agents in childhood cancer preclinical models: meeting summary - Full text - MIT Libraries
PJ Houghton, PC Adamson, S Blaney, HA Fine, R … - Clin. Cancer Res, 2002 - dimscan.com
... kinase Ii (99, 100) and by expression of LMO1 (101) or LMO2 (102). ... sarcoma (non-
rhabdomyosarcoma) Mice that carry linked germ-line mutations in Nf1 and p53 ...
Cited by 8 - View as HTML - Web Search - reprints.nant.org - nant.org - ncbi.nlm.nih.gov - all 5 versions »

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... 2 MINI20 B Muscle initiator sequence-20 MUSCLE INI B Muscle initiator NF1 Q6 Nuclear ...
LMO2COM 01 Complex of Lmo2 bound to Tal-1, E2A proteins, and GATA-1, half ...
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Testing of New Agents in Childhood Cancer Preclinical Models - Full text - MIT Libraries
CE Biomarkers, PMC Therapeutics - Clinical Cancer Research, 2002 - clincancerres.aacrjournals.org
... As an example, JMML has been modeled using Nf1 mutant mice. Approximately
10% of mice with heterozygous inactivation of Nf1 develop ...
Web Search - clincancerres.aacrjournals.org

Members of the GATA family of transcription factors bind to the U3 region of Cas-Br-E and Graffi … - Full text - MIT Libraries
C Barat, E Rassart - J. Virol, 1998 - jvi.asm.org
... Conserved binding sites for other transcription factors (CBF, LVb, NF1, and E-box)
are ... participate in a large oligomeric complex with E47, GATA-1, Lmo2, and Ldb ...
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Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms - Full text - MIT Libraries
ME Massari, C Murre, R Articles - Mol. Cell. Biol, 2000 - dx.doi.org
... to facilitate nucleosome disruption and allow occupancy of the TATA box and NF1
site at ... a chromosomal translocation found in a subset of T-ALLs (9). Lmo2 is a ...
Cited by 292 - Web Search - mcb.asm.org - www-biology.ucsd.edu - sig.biostr.washington.edu - all 9 versions »

Childhood and Adolescent Lymphoid and Myeloid Leukemia - Full text - MIT Libraries
CH Pui, M Schrappe, RC Ribeiro, CM Niemeyer - Hematology, 2004 - asheducationbook.org
... Together with the findings of mutations in RAS and NF1 in the other patients ... basis
of involvement of one or more specific oncogenes: LYL1 plus LMO2, HOX11, TAL1 ...
Cited by 1 - Web Search - dx.doi.org - asheducationbook.org - ncbi.nlm.nih.gov

Mapping and characterization of the mouse and human SS18 genes, two human SS18-like genes and a …
DRH de Bruijn, E Kater-Baats, M Eleveld, G Merkx, … - Cytogenet Cell Genet, 2001 - content.karger.com
... the hematopoietic specific transcription factors IK2, c-ETS I MZF1, LMO2 and GATA1,
as well as the general transcription factors AP2, AP4, SP1, NF1, GC1, TCF11 ...
Cited by 7 - Web Search - content.karger.com - dx.doi.org - karger.com

Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors.
P Haviernik, KD Bunting - Current Gene Therapy, 2004 - ingentaconnect.com
... of transduced cell clones in the SCID leukemia patients was done using the LM-PCR
technique, where integration of the retroviral vector into the LMO2 locus in ...
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Ex vivo culture of Fancc-/-stem/progenitor cells predisposes cells to undergo apoptosis, and … - Full text - MIT Libraries
X Li, MM Le Beau, S Ciccone, FC Yang, B Freie, S … - Blood, 2005 - bloodjournal.org
... LMO2-associated clonal T cell proliferation in two patients after gene therapy ... Nf1
regulates hematopoietic progenitor cell growth and ras signaling in response ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov