Chromosomal abnormalities and tumor development: from genes to therapeutic mechanisms - Full text - MIT Libraries
C Cobaleda, J Perez-Losada, I Sanchez-Garcia - BioEssays, 1998 - doi.wiley.com
... 14)(p13;q11) T-ALL LMO2, TCR- /TCR- t(7;11)(q35;p13) T-ALL TCR- , LMO2 Homeodomain
t ... t(4;16)(q26;p13) T lymphoma IL-2, BCM inv(2;2)(p13;p11–14) NHL REL/NGR inv ...
Cited by 13 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

The hare and the tortoise: an embryonic haematopoietic race - Full text - MIT Libraries
I Godin, A Cumano - Nat Rev Immunol, 2002 - nature.com
... The T-cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis ... The
combined absence of the transcription factors Rel and RelA leads to multiple ...
Cited by 26 - Web Search - nature.com - ncbi.nlm.nih.gov

Coordinated Changes in Classes of Ribosomal Protein Gene Expression Is Associated with Light-Induced … - Full text - MIT Libraries
R Grewal, J Stepczynski, R Kelln, T Erickson, R … - Investigative Ophthalmology & Visual Science, 2004 - iovs.org
... corresponding to the following DNA-binding factors: FoxD3, AP-1, v-Myb, Pax-4, USF,
Oct-1, HNF-3b, CDP CR1, HNF-4, FoxJ2, Evi-1, Lmo2 complex, c-Rel, GATA-1 ...
Cited by 1 - Web Search - dx.doi.org - iovs.org - ncbi.nlm.nih.gov

Cloning and characterization of the proximal murine Phex promoter - Full text - MIT Libraries
S Liu, R Guo, LD Quarles - Endocrinology, 2001 - endo.endojournals.org
... at the position -1573 (30); AP-4 at position -1263 (31); NF-Y at position -1057
(32); C/EBP at position -928 (33); C-Rel at position -897 (34); Lmo2 complex at ...
Cited by 10 - Web Search - endo.endojournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Identification of outcome predictors in diffuse large B-cell lymphoma. Immunohistochemical profiling … - Full text - MIT Libraries
ES PLZ, PPP LA, MT VS, EM GM - Haematologica, 2005 - haematologica.org
... ones, and found that t(14;18) and amplification of the c-rel locus were ... have focused
their attention on six genes (LMO2, BCL6, FN1, CCDN2, SCYA2, and BCL2) and ...
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peer-review
PL Zinzani, S Dirnhofer, E Sabattini, L Alinari, … - haematologica.it
... ones, and found that t(14;18) and amplification of the c-rel locus were ... have focused
their attention on six genes (LMO2, BCL6, FN1, CCDN2, SCYA2, and BCL2) and ...
Cached - Web Search - haematologica.it - haematologica.org - haematologica.org

Notch signaling in leukemia
JC Aster, WS Pear - Curr. Opin. Hematol, 2001 - co-hematology.com
... Moreover, misexpression of TAL1, LMO1, or LMO2, the genes most commonly dysregulated ...
Rel-type transcription factors represent a second potential target for the ...
Cited by 27 - Web Search - co-hematology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Molecular diagnosis of lymphoid malignancies by gene expression profiling
RE Davis, LM Staudt - Curr. Opin. Hematol, 2002 - co-hematology.com
... Germinal center B-like (GCB) DLBCLs express LMO2, CD10, BCL-6, A-myb and ... Amplification
of the c-rel locus of chromosome 2p is another recurrent abnormality in ...
Cited by 21 - Web Search - co-hematology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Physical interaction of the bHLH LYL 1 protein and NF-κB 1 p 105 - Full text - MIT Libraries
R Ferrier, R Nougarede, S Doucet, B Kahn-Perles, J … - Oncogene, 1999 - nature.com
... mediated by specific interactions in erythroid cells with the Lim-only protein LMO2
which is ... NF- B1 belongs to the large NF- B/Rel family and encodes p105 and ...
Cited by 10 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

E 7-expressing HaCaT keratinocyte cells are resistant to oxidative stress-induced cell deathvia the … - Full text - MIT Libraries
JH Shim, KJ Cho, KA Lee, SH Kim, PK Myung, YK Choe … - PROTEOMICS, 2005 - doi.wiley.com
Page 1. R EGULAR A RTICLE E7-expressing HaCaT keratinocyte cells are resistant to
oxidative stress-induced cell death via the induction of catalase ...
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Dynamic spatiotemporal expression of LIM genes and cofactors in the embryonic and postnatal cerebral … - Full text - MIT Libraries
S Bulchand, L Subramanian, S Tole - Developmental Dynamics, 2003 - doi.wiley.com
... an Ap dimer bridged by a CHIP dimer, a process that is regulated by the rel- ative
levels ... The cortical hem displays expres- sion of Clim1a, Lmx1a, and Lmo2 (Fig ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

Comparative Analysis of the Genetic Structure and Chromosomal Mapping of the Murine Gadd45g/CR6 Gene
B HOFFMAN, D LIEBERMANN - DNA AND CELL BIOLOGY, 2003 - dx.doi.org
... al., 2001), the Gadd45g genes also contains C/EBPb, NF-kappaB/c-Rel and STATx ... criteria
for the for- mation of enhanceosomes with DNA elements for Lmo2 at 2583 ...
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Journal of Medicine
A Rosenwald, G Wright, WC Chan, JM Connors, E … - llmpp.nih.gov
... A-myb Gene LMO2 Jnk3 CD10 bcl-6 Cyclin D2 IRF-4 Flip CD44 0.0 1.0 C 0 10 0.2 0.4
0.6 ... Oncogenic Abnormality c-rel amplification bcl-2 t(14;18) 17 26 0 0 0 0 no. ...
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Embryonic stem cells and transgenic mice in the study of hematopoiesis
SH Orkin - Int. J. Dev. Biol, 1998 - ijdb.ehu.es
... regulatory network and the leukemic oncoproteins SCL/tal-1 and Rbtn2/Lmo2. ... molecular
approaches enriches our understanding of the biological rel- evance and ...
Cited by 29 - View as HTML - Web Search - ijdb.ehu.es - ncbi.nlm.nih.gov - Get it from MIT Libraries

[CITATION] Journal of Medicine
A Conclusions
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Progress in Hematology
KJ Savage, RD Gascoyne - Int J Hematol, 2004 - cardenjennings.metapress.com
... a hallmark of germinal center B-cells [8]. Interestingly, although c-REL amplifica-
tion ... striking impact on outcome (BCL6, cyclin D2, BCL2, SCYA3, LMO2, and FN1 ...
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Stem cell leukaemia gene and its role in normal and leukaemic haematopoiesis
CG Begley - haematologica.org
... The mechanisms by which SCL is controlled are rel- atively poorly understood. ... ization
between Lmo2 (Rbtn2) and Tal1 alters thy- mocyte development and ...
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Transcript profiling of human dendritic cells maturation-induced under defined culture conditions: … - Full text - MIT Libraries
F Moschella, A Maffei, RP Catanzaro, KP … - British Journal of Haematology, 2001 - ingentaconnect.com
... formed one cluster, displaying increased expression of erg B, aml-1 and LMO2. ... grouping,
these mature DCs showed enhanced expression of c-rel, homeobox protein ...
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Recent advances in the molecular diagnosis of diffuse large B-cell lymphoma
K Fu, J Iqbal, WC Chan - Expert Rev. Mol. Diagn, 2005 - future-drugs.com
... A-myb LMO2 Jnk3 CD10 Bcl-6 ... The amplification of the c-rel gene on chromosome 2p
occurs much more frequently in PMBL than GCB- or ABC- DLBCL. ...
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TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... 27 The LMO2 Master Gene; Its Role as a Transcription Regulator Determining
Cell Fate in Leukemogenesis and in Hematopoiesis 483 ...
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Genomic approaches to hematologic malignancies - Full text - MIT Libraries
BL Ebert, TR Golub - Blood, 2004 - bloodjournal.org
... expression of the key oncogenes HOX11, TAL1 (SCL), LYL1, LMO1, and LMO2 and indicated ...
2 gene, was present in 26 cases, and amplification of the c-rel gene was ...
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New Molecular Methods for Classification, Diagnosis and Therapy Prediction of Hematological … - Full text - MIT Libraries
A Zvara, L Hackler Jr, BZ Nagy, T Micsik, LG … - Pathol. Oncol. Res, 2002 - webio.hu
... with fluorescent antibodies, the direct visualization of the rel- ative position
of ... that important for cell-maturation (eg HOX11, LMO1, LMO2) become regulated ...
Cited by 1 - View as HTML - Web Search - ncbi.nlm.nih.gov - webio.hu

Transcriptional Control of T Lymphocyte Differentiation - Full text - MIT Libraries
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - Stem Cells, 2001 - stemcells.alphamedpress.org
... erythroid cells containing TAL1-E2A heterodimers as well as LMO1 and LMO2 proteins
[57 ... identified in the Il2 minimal promoter such as the NF- B/Rel factors and ...
Cited by 17 - Web Search - dx.doi.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Cross-linked Small Polyethylenimines: While Still Nontoxic, Deliver DNA Efficiently to Mammalian …
M Thomas, Q Ge, JJ Lu, J Chen, A Klibanov - Pharmaceutical Research, 2005 - springerlink.com
... ln rel /c, where rel t solution /t solvent and c is the concentra- tion ... LMO2- associated
clonal T cell proliferation in two patients after gene therapy for SCID ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

[PS] Framework and formalism for expressing ontologies
B Wielinga, AT Schreiber, W Jansweijer, A … - ESPRIT Project, 1994 - www-old.swi.psy.uva.nl
Page 1. KACTUS Esprit Project 8145 Framework and Formalism for Expressing
Ontologies Bob Wielinga Guus Schreiber Wouter Jansweijer ...
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CL-46, a novel collectin highly expressed in bovine thymus and liver - Full text - MIT Libraries
S Hansen, D Holm, V Moeller, L Vitved, C Bendixen, … - J. Immunol, 2002 - jimmunol.org
... B, c-Rel, and the gut-enriched Krueppel-like factor (28, 29). Besides the sites
listed in Table I, several potential sites for the factors, Gata1-3, Lmo2, MZF1 ...
Cited by 10 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 6 versions »

Molecular and Genetic Mechanisms of Lymphomagenesis
R Kušec - cmj.hr
... V(D)J-mediated translocations in lymphoid neoplasm – type 1 and type 2. Type 1 are
translocations involv- ing LMO2, TAL2, and ... REL 2p13 gene amplification ...
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Regulation and function of transcription factor GATA-1 during red blood cell differentiation - Full text - MIT Libraries
K Briegel, P Bartunek, G Stengl, KC Lim, H Beug, … - Development, 1996 - dev.biologists.org
... transcription factor Tal-1/SCL and the LIM domain transcription factor LMO2 (previously
called ... ER antibody detected the expected 90×10 3 M r v-rel/ER fusion ...
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Studies of the Ribosomal Protein S19 in Erythropoiesis
H MATSSON - publications.uu.se
... devel- opment is regulated by several transcription factors including TAL1, LMO2
and GATA2 (4 ... of a putative site for the transcription factors c-Rel and Rel-a ...
Web Search - diva-portal.org

S tem C ells
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - immuneweb.xxmc.edu.cn
Page 1. Transcriptional Control of T Lymphocyte Differentiation F RANK
JT S TAAL , a F LOOR W EERKAMP , a A NTON W. L ANGERAK , a ...
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Expression of Galectin-3 in Skeletal Tissues Is Controlled by Runx 2 - Full text - MIT Libraries
M Stock, H Schaefer, S Stricker, G Gross, S … - J Biol Chem, 2003 - jbc.org
... binding sites for AP1, AP4, C/EBP , CDP CR, c-Ets, CP2, c-Rel, GATA proteins, GFI1,
HNF3b, Ikaros factors, Lmo2 complex, MyoD, MZF1, NF1, NF-AT, NF- B, NFY, Nkx ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov

Searching for cis-elements in Mouse-Human Orthologous Promoter Regions
N Polouliakh, W Fujibuchi, T Natsume, P Horton - jsbi.org
... NF -Y NR F - 2 Oc t _ 1 GATA-1 Ha nd1/E47 US F Nkx2-5 Sox-5 c- Rel C C AAT CRE-
B P1 F OXD3 RFX 1 S OX-9 ATF CP2 CRE- Ik-1 C HOP - E47 HNF -3be t a Lmo2 GATA-2 ...
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Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia - Full text - MIT Libraries
R Hubmann, JD Schwarzmeier, M Shehata, M Hilgarth, … - Blood, 2002 - bloodjournal.org
... 29 several potential binding sites for Ikaros (IK1-2), GATA1-3, LMO2, and MZF1 ...
Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression ...
Cited by 17 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... not CAGG LMO2COM 01 Complex of Lmo2 bound to Tal-1, E2A proteins, and
GATA-1, half-site 1 Core should be CAGGTG not CAGG E47 01 ...
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Annual Report 2002-2003
FP Board - 2003 - crg.es
Page 1. Annual Report 2002-2003 SCIENTIFIC BOARD Page 2. CENTRE DE REGULACIÓ GENÒMICA
Annual Report 2002-2003 SCIENTIFIC BOARD Design by Estudi Freixes ...
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Ectopic TAL-1/SCL expression in phenotypically normal or leukemic myeloid precursors: proliferative … - Full text - MIT Libraries
GL Condorelli, A Tocci, R Botta, F Facchiano, U … - Mol Cell Biol, 1997 - mcb.asm.org
... Further- more, tal-1 is associated in complex with Lmo2/rbtn-2 protein in erythroid
(54; also, unpublished data) and T leukemic (58) cells. ...
Cited by 29 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

Comparison of genome profiles for identification of distinct subgroups of diffuse large B-cell … - Full text - MIT Libraries
H Tagawa, M Suguro, S Tsuzuki, K Matsuo, S Karnan, … - Blood, 2005 - bloodjournal.org
... These 67 genes are BARD1, PIK3CG, LRMP, Hs.1098, BCL6, HDAC1, MYBL2, MME (CD10),
STAG3, LMO2, APS, Hs.151051, ADPRT, ITPKB, REL, FLJ20094 Hs.211563, MEF2B, CD44 ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Regulation OF Lymphoid Development,
N Pathway - arjournals.annualreviews.org
... 28). Interactions with other key factors in this process, such as LMO2,
GATA-2, AML1, and SCL/Tal-1, need to be explored. Ligand ...
Web Search - arjournals.annualreviews.org

CONSEQUENCES OF CHROMOSOMAL ABNORMALITIES IN TUMOR DEVELOPMENT - Full text - MIT Libraries
I Sanchez-Garcia - Annual Review of Genetics, 1997 - dx.doi.org
... abnormalities have been particularly informative about recombinase involvement,
especially breakpoints within the chromosome band 11p13 that activate LMO2 (112 ...
Cited by 25 - Web Search - wwwlib.bionet.nsc.ru - genet.annualreviews.org - ncbi.nlm.nih.gov - all 6 versions »

Lentiviral vectors transcriptionally targeted to hematopoietic cells by WASP gene proximal promoter …
G Therapy - Gene Therapy, 2005 - nature.com
... hematopoietic transcription factors (two for Ets-1, one for c-Rel, and one ...
LMO2-associated clonal T cell proliferation in two patients after gene therapy for ...
Web Search - nature.com

The remarkable photochemistry of quadruply bonded metal-metal complexes
DG Nocera - Journal of Cluster Science, 1994 - springerlink.com
... » For )-x= 313 nm. Data taken from Rel. 16. ... 4.0 20 0,0 -- lAl9(gg" ) 1A2u (Sa')
)aA2 (88") 1A19 (8 2) Cl Cl CHCH LMo2[O2P(OPh)] 4 CI - = (CHGH , CIMoi"Mo ") ...
Web Search

Luciferase Reporters: Less is More
A Paguio, B Almond, F Fan, P Stecha, D Garvin, M … - promega.com
... Sox-5 HoxC-Rel HNF1 CDE HNF3 HNF4 MEIS1 Msx-1 Pax2/5/8 TALE GBF1 E4BP4 Arnt
FAST-1/Smad WTS STs S8 Pro L HLF NF Y NF-kB MRE MIS POZ HLF SF1 Tax Lmo2 ST/TA RP58 ...
Web Search

Cloning, genomic organization, expression, and effect on h-casein promoter activity of a novel … - Full text - MIT Libraries
FQ Zhao, Y Zheng, B Dong, T Oka - Gene, 2004 - uvm.edu
... M00203), c-Rel (M00053), AP-2 (M00189), GC (M00255), MZF1 (M00083 and M00084),
c-Myb (M00183), c-Ets-1 (M00074 and M00032), cap (M00253), Lmo2 (M00277), Freac ...
Cited by 1 - View as HTML - Web Search - w3.ualg.pt - ncbi.nlm.nih.gov

Acute Lymphoblastic Leukemia - Full text - MIT Libraries
D Hoelzer, N Gokbuget, O Ottmann, CH Pui, MV … - Hematology, 2002 - asheducationbook.org
Page 1. 162 American Society of Hematology Acute Lymphoblastic Leukemia
Dieter Hoelzer, Nicola Gökbuget, Oliver Ottmann, Ching-Hon ...
Cited by 23 - Web Search - ohsu.edu - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Microarray Analysis of B-Cell Lymphoma Cell Lines with the t (14; 18)
RS Robetorye, SD Bohling, JW Morgan, GC Fillmore, … - Mol. Diagn, 2004 - jmd.amjpathol.org
... Calculation of fold in- crease or decrease in expression of selected genes rel-
ative to expression levels in tonsillar B-cells was accom- plished using the ...
Cited by 6 - Web Search - jmd.amjpathol.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

by RNA interference - Full text - MIT Libraries
ZJ Chen, BT Kren, YPW Phillip, WC Low, CJ Steer - Biochemical and Biophysical Research Communications, 2005 - huntington.pl
... with zeocin, the levels of Htt mRNA were significantly decreased rel- ative to ... Rabbitts,
F. Le Deist, A. Fischer, M. Cavazzana-Calvo, LMO2- associated clonal T ...
Cited by 1 - View as HTML - Web Search - ncbi.nlm.nih.gov

The Group 3 LIM Domain Protein Paxillin Potentiates Androgen Receptor Transactivation in Prostate … - Full text - MIT Libraries
M Kasai, J Guerrero-Santoro, R Friedman, ES Leman, … - Cancer Res, 2003 - intl-cancerres.aacrjournals.org
... contain a homeodomain, such as Lhx-3/P-LIM, bind directly to specific transcriptional
regulatory sites (59) , some LIMO proteins, such as LMO2, are recruited ...
Cited by 4 - Web Search - pharmacology.case.edu - pharmacology.cwru.edu - 129.22.208.68 - all 8 versions »

Lentiviral vectors transcriptionally targeted to hematopoietic cells by WASP gene proximal promoter …
IJ Molina - Gene Therapy, 2005 - nature.com
... have characterized a 170 bp fragment containing four potential binding sites for
hematopoietic transcription factors (two for Ets-1, one for c-Rel and one for ...
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Characterization of Interactions between Transcription Factors and a Regulatory Region Spanning nt …
LA Pereira, MJ Churchill, AG Elefanty, T Gouskos, … - Journal of Biomedical Science, 2002 - content.karger.com
Page 1. Original Paper J Biomed Sci 2002;9:68–81 Characterization of Interactions
between Transcription Factors and a Regulatory Region ...
Cited by 4 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

NHL-BFM
B im Kindes - kinderkrebsinfo.de
... Genetik t(1;7) TAL1/TCRß t(1;7) LCK/TCRß t(8;14) C-MYC/TCRa/d t(11;14)
LMO1/TCRa/d t(11;14) LMO2/TCRa/d t(10;14) HOX11/TCRa/d t(1;14) TAL1TZRa/d ... MAL, REL + ...
View as HTML - Web Search - kinderkrebsinfo.de