THE LMO2 MASTER GENE; ITS ROLE AS A TRANSCRIPTION REGULATOR DETERMINING CELL FATE IN LEUKEMOGENESIS …
C TRANSLOCATIONS, D REGULATION - doi.wiley.com
... hematopoiesis. It is important to note in rela- tion to development of
T-cell tumors that Lmo2 is not expressed in mature T cells. ...
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This Week IN
C Salts, P Resonances - sciencemag.org
... up-regulation of LMO2 apparently stimu- lated unchecked clonal T cell proliferation.
Sexual Deception by Orchids In most plant-pollinator rela- tionships, the ...
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Perspectives
NC Ahead - olemiss.edu
... themselves have remained healthy over prolonged periods of observation (5). The
LMO2 gene encodes ... oilseed rape forms hy- brids with some of its wild rela- tives ...
View as HTML - Web Search - olemiss.edu - hartford-specialty.com

Genomic structure, alternative transcripts and chromosome location of the human LIM domain binding …
M Drechsler, V Schumacher, S Friedrich, G … - Cytogenet Cell Genet, 1999 - content.karger.com
... In a complex with other protein factors like LMO2 and SCL, Nli/Ldb1 regulates ery ...
on formation of a functional complex with Chip and that the rela- tive levels ...
Cited by 2 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

The hare and the tortoise: an embryonic haematopoietic race - Full text - MIT Libraries
I Godin, A Cumano - Nat Rev Immunol, 2002 - nature.com
... The T-cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis ... The
combined absence of the transcription factors Rel and RelA leads to multiple ...
Cited by 26 - Web Search - nature.com - ncbi.nlm.nih.gov

Report from the 2 ndStem Cell Clonality and Genotoxicity Retreat
RM Frederickson - Molecular Therapy, 2005 - asgt.org
... progenitors may have predisposed the cells to transformation by LMO2 expression
and ... pointed out by the previous speaker, he suggested that rela- tively simple ...
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Expression profiling in cancer using gene chips - Full text - MIT Libraries
J Nasir - Clinical Genetics, 2000 - ingentaconnect.com
... CLL were found next to resting B cells, reflecting their rela- tively low ... previously
associated with translocation events including BCL-6, BCL- 7A and LMO2. ...
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Progress in Hematology
R Ono, T Nosaka, Y Hayashi - Int J Hematol, 2005 - cardenjennings.metapress.com
... 2]. The genes identified to date include Tal1/SCL and LMO2/rbtn2, which ... little sequence
homology among the various MLL fusion partners, the rela- tionships of ...
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Modulating gene expression in stem cells without recombinant DNA and permanent genetic modification. - Full text - MIT Libraries
BC Heng, YHHT Cao - Cell Tissue Res, 2005 - springerlink.com
... cell proliferation, which was driven by retrovirus enhancer activity on the LMO2
promoter ... 2004), it is rela- tively easy to covalently link PTD sequences to PNA ...
Web Search - ncbi.nlm.nih.gov

Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem … - Full text - MIT Libraries
S Gerecht-Nir, JE Dazard, M Golan-Mashiach, S … - Developmental Dynamics, 2005 - doi.wiley.com
... cells were also observed and included TAL1, a basic helix-loop-helix protein; and
LMO2, a LIM-Zn finger protein; both of which are expressed in early ...
Cited by 2 - Web Search - weizmann.ac.il - weizmann.ac.il - ncbi.nlm.nih.gov

Gene therapy of monogenic and cardiovascular disorders
P Blomberg, CIE Smith - Expert Opinion on Biological Therapy, 2003 - dx.doi.org
... [8] . Limitations of the current retrovirus vectors are their rela- tively low titres,
their ... the retroviral vector into the same gene locus, the LMO2 gene [8,32 ...
Web Search - extenza-eps.com - ashley-pub.com - ingentaconnect.com - all 9 versions »

Choose your fate: artery, vein or lymphatic vessel?
NL Harvey, G Oliver - Current Opinion in Genetics & Development, 2004 - stjude.org
... the Lin-11, Isl-1 and Mec-3 genes) domain protein Lmo2 induce the ... EphrinB2 and EphB4,
acting via a ligand–receptor rela- tionship, have also been implicated ...
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From the yolk sac to the spleen: new roles for Notch in regulating hematopoiesis - Full text - MIT Libraries
I Maillard, Y He, WS Pear - Immunity, 2003 - microbio.uab.edu
... known to be involved in the generation of early hematopoietic progenitors, such
as the transcription factors SCL/Tal-1, GATA-2, LMO2, AML1, HoxB4 ... The rela- ...
Cited by 4 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Bioinformatic Analyses of the Bacterial L-Ascorbate Phosphotransferase System Permease Family
RHABC Milton, H Saier Jr - J Mol Microbiol Biotechnol, 2003 - content.karger.com
... 90 16801861 144 Listeria monocytogenes EGD-e gram+ bacteria Lmo2 16804686
432 11 16804687 90 16804688 144 Listeria monocytogenes ...
Cited by 2 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Deregulated expression of the TAL1 gene by t (1; 5)(p32; q31) in patient with T-cell acute …
S Francois, E Delabesse, L Baranger, M Dautel, C … - GENES, CHROMOSOMES & CANCER, 1998 - doi.wiley.com
... of tumor formation in transgenic mice already overex- pressing LMO2 (RHOMBOTIN2)
(Larson ... Taken together with the rela- tively subtle nature of the chromosomal ...
Cited by 8 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Luciferase Reporters: Less is More
A Paguio, B Almond, F Fan, P Stecha, D Garvin, M … - promega.com
... BACH1 GBF1 AD-b FLI Hox1.3 CREB CREB PAR PAR Lmo2 KLF3 Cut-like Pax-3 Pax1 Pax1
Pax1 AC-t ... 100,000 1,000,000 10,000,000 Luminescence (Rela t ive Ligh t Uni t s) ...
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Transcriptional Control of T Lymphocyte Differentiation - Full text - MIT Libraries
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - Stem Cells, 2001 - stemcells.alphamedpress.org
... in erythroid cells containing TAL1-E2A heterodimers as well as LMO1 and LMO2 proteins
[57 ... TF family includes NF- B1 (p50/p105), NF- B2 (p52/p100), RelA (p65), c ...
Cited by 17 - Web Search - dx.doi.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Progress in Hematology
KJ Savage, RD Gascoyne - Int J Hematol, 2004 - cardenjennings.metapress.com
... the most striking impact on outcome (BCL6, cyclin D2, BCL2, SCYA3, LMO2, and FN1 ...
genomic gain was noted for the majority of analyzed genes (eg, RelA, MYC, BCL2 ...
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Molecular heterogeneity of regulatory elements of the mouse GATA-1 gene
A Ronchi, M Ciro, L Cairns, L Basilico, P Corbella … - Genes Funct, 1997 - ingentaconnect.com
... The rela- tively strong site 2 corresponds to the previously characterized promoter ...
Interestingly, it was recently shown that Lmo2 and Tal1, two factors crucial ...
Cited by 7 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Characterization of Interactions between Transcription Factors and a Regulatory Region Spanning nt …
LA Pereira, MJ Churchill, AG Elefanty, T Gouskos, … - Journal of Biomedical Science, 2002 - content.karger.com
Page 1. Original Paper J Biomed Sci 2002;9:68–81 Characterization of Interactions
between Transcription Factors and a Regulatory Region ...
Cited by 4 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

[PS] SHADE: Technology for Knowledge-Based Collaborative Engineering
JG McGuire, DR Kuokka, JC Weber, JM Tenenbaum, TR … - Journal of Concurrent Engineering: Applications and Research …, 1993 - ksl.stanford.edu
... must be demonstrated as being expressive enough to bridge rela- tionships among ... Report,
Digital Equipment Cor- poration, 111 Locke Drive (LMO2/K11), Marlboro ...
Cited by 80 - View as HTML - Web Search - edge.mcs.drexel.edu - ksl-web.stanford.edu - ksl.stanford.edu - all 7 versions »

S tem C ells
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - immuneweb.xxmc.edu.cn
Page 1. Transcriptional Control of T Lymphocyte Differentiation F RANK
JT S TAAL , a F LOOR W EERKAMP , a A NTON W. L ANGERAK , a ...
View as HTML - Web Search

Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic … - Full text - MIT Libraries
E Missiaglia, E Blaveri, B Terris, YH Wang, E … - International Journal of Cancer, 2004 - doi.wiley.com
Page 1. ANALYSIS OF GENE EXPRESSION IN CANCER CELL LINES IDENTIFIES CANDIDATE
MARKERS FOR PANCREATIC TUMORIGENESIS AND METASTASIS ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

State-of-the-Art Review on Vascular Stem Cells and Angiogenesis
A EICHMANN, LUC PARDANAUD, LI YUAN, D MOYON - JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH, 2002 - dx.doi.org
... 1A); however, no further information concerning a possible clonal rela- tion between ...
Lmo2 and GATA-3 associated expression in intraembryonic he- mogenic sites. ...
Web Search - liebertonline.com - liebertonline.com

SHADE: Technology for knowledge-based collaborative engineering
DR Kuokka, JG McGuire, JC Weber, JM Tenenbaum, TR … - Journal of Concurrent Engineering: Applications and Research, 1993 - edge.mcs.drexel.edu
... must be demonstrated as being expressive enough to bridge rela- tionships among ... Report,
Digital Equipment Cor- poration, 111 Locke Drive (LMO2/K11), Marlboro ...
Cited by 15 - View as HTML - Web Search

Cross-linked Small Polyethylenimines: While Still Nontoxic, Deliver DNA Efficiently to Mammalian …
M Thomas, Q Ge, JJ Lu, J Chen, A Klibanov - Pharmaceutical Research, 2005 - springerlink.com
... the applicability of the conjugates in vivo, particularly as rela- tively high ... LMO2-
associated clonal T cell proliferation in two patients after gene therapy ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Chromatin structure and transcriptional regulation of the stem cell leukaemia (SCL) gene in mast …
JL Fordham, B Gottgens, F McLaughlin, AR Green - Leukemia, 1999 - nature.com
... By contrast, the addition of +17/+18HS resulted in a 3.5-fold increase in luciferase
activity over −0.2E3 and a 1350-fold increase rela- tive to pGL2 basic. ...
Cited by 5 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

The Group 3 LIM Domain Protein Paxillin Potentiates Androgen Receptor Transactivation in Prostate … - Full text - MIT Libraries
M Kasai, J Guerrero-Santoro, R Friedman, ES Leman, … - Cancer Res, 2003 - intl-cancerres.aacrjournals.org
... as a thyroid hormone-interacting protein (40) , functions as a relA coactivator
(51) . ... regulatory sites (59) , some LIMO proteins, such as LMO2, are recruited ...
Cited by 4 - Web Search - pharmacology.case.edu - pharmacology.cwru.edu - 129.22.208.68 - all 8 versions »

Gene therapy in primary immunodeficiencies
AJ Thrasher, HB Gaspar - future-drugs.com
... The rela- tive risk for each type of vector modification needs to be deter- mined
in clinically relevant animal-model systems and the effectiveness of these ...
Web Search - future-drugs.com

CLUB ESPANOL DE CITOLOGIA HEMATOLOGICA: EL LINFOBLASTO EN EL CONTEXTO
A DE LA LEUCEMIA LINFOBLASTICA - db2.doyma.es
Page 1. CLUB ESPAÑOL DE CITOLOGÍA HEMATOLÓGICA: EL LINFOBLASTO EN EL CONTEXTO DE
LA LEUCEMIA LINFOBLÁSTICA AGUDA C OORDINADORAS : M.ªC. J IMÉNEZ . ...
View as HTML - Web Search

abaxial cell fate in ago1 indicates that miRNA regulation is required for leaf polarity. Other … - Full text - MIT Libraries
MT Juarez, JS Kui, J Thomas, BA Heller, MCP … - Genes Dev, 2002 - nature.com
... Consistent with the rela- tively low abundance of precursor transcripts 9,14–17 ,
no hybridiz- ation was detected using probes excluding the miRNA (data not ...
Web Search - nature.com

Genetic Vaccines and Therapy - Full text - MIT Libraries
DS Anson - Genetic Vaccines and Therapy, 2004 - immuneweb.xxmc.edu.cn
... a recent movement of HIV into the population with a resulting imbalance between
viral pathogenicity and host defences, which, after a rela- tively long period ...
View as HTML - Web Search - bmc.ub.uni-potsdam.de

[PS] Assumptions of Problem-Solving Methods
VR Benjamins, C Pierret-Golbreich - EKAW, 1996 - lri.fr
... A causal model could be referred to by a static role of a Psm and can be
described as a set of states ST related by causal rela- ...
Cited by 24 - View as HTML - Web Search - lri.fr - portal.acm.org

Epstein-BarrVirus (EBV) LMP2Ainduces alterations in gene transcription similar to those observed in … - Full text - MIT Libraries
L LMP2Atransgenicmice, L humanB-celllines - BLOOD, 2003 - bugs.mimnet.northwestern.edu
... Ebf, Pax-5, Lef-1, and Spi-B (Table 2). 25 Other transcription factors repressed
by LMP2A included E4f, Ets2, Nf-y (bone marrow); Bcl-6, Lmo2, Nfkb2 (spleen ...
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Serpa Cheese: Technological, biochemical and microbiological characterisation of a PDO ewe's milk …
LB Roseiro, R Andrew Wilbey, M Barbosa - Le Lait, 2003 - edpsciences.org
... The other, dairy C, was a rela- tively new dairy that produced Serpa cheese using
the traditional approach with some improvements of the technology on a semi ...
Web Search - edpsciences.org - dx.doi.org

Human immunodeficiency virus type 1 (HIV-1) derived vectors: safety considerations and controversy …
G ROMANO, PP CLAUDIO, T TONINI, A GIORDANO - Eur J Dermatol, 2003 - john-libbey-eurotext.fr
... Rela- tively healthier patients are therefore excluded from gene therapy clinical ...
effect of chromosomal translocations in acute leukemias: the LMO2 paradigm in ...
Cited by 1 - View as HTML - Web Search - john-libbey-eurotext.fr - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulation and function of transcription factor GATA-1 during red blood cell differentiation - Full text - MIT Libraries
K Briegel, P Bartunek, G Stengl, KC Lim, H Beug, … - Development, 1996 - dev.biologists.org
... helix-loop-helix (bHLH) transcription factor Tal-1/SCL and the LIM domain transcription
factor LMO2 (previously called rbtn-2) are essential for establishment ...
Cited by 24 - Web Search - wwwlib.bionet.nsc.ru - dev.biologists.org - ncbi.nlm.nih.gov

PAINT: A Promoter Analysis and Interaction Network Generation Tool for Gene Regulatory Network …
R Vadigepalli, P Chakravarthula, DE Zak, JS … - Omics A Journal of Integrative Biology, 2003 - dx.doi.org
... this distribution is monotonically de- creasing indicating that most of the TREs
are present on few genes each (fine-tuned regulation) and rela- tively few ...
Cited by 4 - Web Search - liebertonline.com - che.udel.edu - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Therapy for haemophilia: recent advances and goals for the future
G Young, L Aledort - Expert Opinion on Emerging Drugs, 2005 - dx.doi.org
... Considering the rela- tively short half-life of both recombinant FVIII and FIX,
once-weekly therapy leaves a sizable period of time when there is no measurable ...
Web Search - ingentaconnect.com - ashley-pub.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

[PS] Framework and formalism for expressing ontologies
B Wielinga, AT Schreiber, W Jansweijer, A … - ESPRIT Project, 1994 - www-old.swi.psy.uva.nl
Page 1. KACTUS Esprit Project 8145 Framework and Formalism for Expressing
Ontologies Bob Wielinga Guus Schreiber Wouter Jansweijer ...
Cited by 16 - View as HTML - Web Search - swi.psy.uva.nl

BLOOD - Full text - MIT Libraries
RA Shivdasani, SH Orkin - Blood, 1996 - bloodjournal.org
... call for due caution in interpreting the results of gene knockouts in a single mouse
train.4' A DIFFERENTIATION ARREST PHENOCOPY THE CASE OF rbtn2/LMO2 The Lim ...
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BMC Biotechnology - Full text - MIT Libraries
BMC Biotechnology - BMC Biotechnology, 2005 - biomedcentral.com
... MBP fusions (Table 4). In several cases (ELF1, Fli1, Ldb1, BC031407, Nfkb1
and RelA-p65) truncating the proteins to minimise the ...
View as HTML - Web Search - dx.doi.org - gdrs-intranet.ath.cx - botany.sinica.edu.tw - all 6 versions »

Effective Lagrangians and Field Algebras with Chiral Symmetry - Full text - MIT Libraries
S GASIOROWICZ, DA GEFFEN - Reviews of Modern Physics, 1969 - link.aps.org
... The nomenclature is related to the commutation rela - tions [Q±A, Q+B] =
ieABCQ+0, (3.2) [Q ... 2 ) = 49,,4 . ( -,a/, aX 4 ) 2 20= - 1- ( Fup)2-!(G;,,v )2+lMO2( ...
Cited by 204 - Web Search - adsabs.harvard.edu

C01.
W Aberer, C Foti, JD Johansen, S Seidenari, F … - DERMATITIS - blackwell-synergy.com
... dermatitis. The proposed instrument might be useful in further studies on
contact dermatitis and occupationally rela- ted hand eczema. ...
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Biomedicine and Diseases: Review The Wiskott-Aldrich syndrome
JS Orange, KD Stone, SE Turvey, K Krzewski - springerlink.com
Page 1. Biomedicine and Diseases: Review The Wiskott-Aldrich syndrome JS
Orange a, *, KD Stone b , S. E.Turvey c and K. Krzewski d ...
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Anna Aris i Giralt
DG i de Microbiologia - tdx.cesca.es
... de la leucèmia murina (5), es produïa mutagènesi insercional per integració del
vector en la regió reguladora d’un oncogen del cromosoma 11 anomenat Lmo2 ...
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