Oligo GEArray® Human Hematopoietic Stem Cells and Hematopoiesis Microarray
S Conditions - search.cosmobio.co.jp
... ASH2L, BCL11A, CD164, CSF1, DLL1, ERAF, FEZ2, FUT10, IFI16, IL10, IL20, IL31RA,
JAG1, LMO2, MLF1, MMP9 ... JAK-STAT cascade: IL31RA, SOCS5, STAT1, STAT3, STAT4. ...
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Immune Deficiencies Due to Defects in Cytokine Signaling - Full text - MIT Libraries
J Kelly, WJ Leonard - Current Science, 2003 - current-reports.com
... Four JAKs (Jak1, Jak2, Jak3, and Tyk2) and seven STATs (Stat1, Stat2, Stat3, Stat4,
Stat5a, Stat5b, and Stat6) have been identified in mammals [2, 3]. ...
Cited by 1 - Web Search - current-reports.com - biomedcentral.com - ncbi.nlm.nih.gov - all 5 versions »

Modulation of the Interleukin-6 Receptor Subunit Glycoprotein 130 Complex and Its Signaling by LMO 4 …
V Novotny-Diermayr, B Lin, L Gu, X Cao - Journal of Biological Chemistry - jbc.org
... In our experiments we also detected associations of LMO2 with Jak1 and gp130 ... and
hematopoiesis and for erythropoiesis, respectively (42), and Stat3 and Stat5 ...
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New insights into erythropoiesis
MJ Koury, ST Sawyer, SJ Brandt - Curr Opin Hematol, 2002 - co-hematology.com
... factors GATA-1 and TAL1 (or SCL) and the LIM domain protein LMO2 [2]. This ... When
erythropoietin receptor was mutated to activate STAT3 instead of STAT5, neither ...
Cited by 24 - Web Search - co-hematology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The‘definitive’(and‘primitive’) guide to zebrafish hematopoiesis - Full text - MIT Libraries
AJ Davidson, LI Zon - Oncogene, 2004 - nature.com
... (2000b) ldb1 LIM domain binding — Toyama et al. (1998) lmo2 LIM domain — Thompson
et al. (1998) ... (1998) stat3 STAT — Oates et al. (1999) ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Interleukin-7 in T-cell acute lymphoblastic leukemia: An extrinsic factor supporting leukemogenesis?
J Barata, A Cardoso, V Boussiotis - Leukemia & Lymphoma, 2005 - dx.doi.org
... of the bHLH (MYC, TAL1, TAL2, LYL1, BHLHB1), LIM (LMO1, LMO2) and homeodomain ... have
been characterized in mammalian cells: STAT1, STAT2, STAT3, STAT4, STAT5a ...
Web Search - taylorandfrancis.metapress.com

Zebrafish: An emerging genetic model for the study of cytokines and hematopoiesis in the era of …
GJ Lieschke - Int. J. Hematol, 2001 - cardenjennings.metapress.com
... reference 24, NP_032116; gata1 U18311, S04655 [24]; lmo2 AF191560, NM_008505 ... AJ005690,
NM_008413 [30]; stat1 AJ005692, NM_009283 [31]; stat3 AJ005693, U30709 ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

RNA interference as a potential tool in the treatment of leukaemia
A Borkhardt, O Heidenreich - Expert Opinion on Biological Therapy, 2004 - extenza-eps.com
... Whereas STAT1 mainly has a differentiation-supportive and antiproliferative role,
STAT3 and -5 have been shown to sup- port tumour proliferation. ...
Web Search - ashley-pub.com - dx.doi.org - ingentaconnect.com - all 8 versions »

The Kinetic Status of Hematopoietic Stem Cell Subpopulations Underlies a Differential Expression of … - Full text - MIT Libraries
R Manfredini, R Zini, S Salati, M Siena, E … - Stem Cells, 2005 - stemcells.alphamedpress.org
... stimulatory effects of interferon-gamma due to phosphorylation of Stat1 and Stat3. ...
The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA ...
Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov

Recent advances in the molecular diagnosis of diffuse large B-cell lymphoma
K Fu, J Iqbal, WC Chan - Expert Rev. Mol. Diagn, 2005 - future-drugs.com
... Subgroup of DLBCL 0.25 0.50 1.00 2.00 4.00 Relative level of expression (× median
value) A-myb LMO2 Jnk3 CD10 Bcl-6 Cyclin D2 IRF-4 Flip CD44 Probability ...
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TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... 27 The LMO2 Master Gene; Its Role as a Transcription Regulator Determining
Cell Fate in Leukemogenesis and in Hematopoiesis 483 ...
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The origin of hematopoietic cell type diversity - Full text - MIT Libraries
T Hoang - Oncogene, 2004 - nature.com
... LMO2 ... between self-renewal and differentiation in ES cells appears to depend on the
balance between the BMP-Smad (acting via Id) and the LIF-STAT3 path- ways ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Cytokines and immunodeficiency diseases: critical roles of the gammac-dependent cytokines … - Full text - MIT Libraries
PE Kovanen, WJ Leonard - Immunological Reviews, 2004 - blackwell-synergy.com
Full Article. View/Print PDF article (774K). Download to reference manager.
Immunological Reviews Volume 202 Issue 1 Page 67 - December ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... not CAGG LMO2COM 01 Complex of Lmo2 bound to Tal-1, E2A proteins, and
GATA-1, half-site 1 Core should be CAGGTG not CAGG E47 01 ...
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Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expression … - Full text - MIT Libraries
AC Oates, A Brownlie, SJ Pratt, DV Irvine, EC Liao … - Blood, 1999 - bloodjournal.org
... nomenclature for alternately spliced forms of the mammalian STAT1 and STAT3 genes ...
hematopoietic stem cells (HSCs) and progenitor cells such as scl, lmo2, 73 and ...
Cited by 27 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

GATA-2/estrogen receptor chimera regulates cytokine-dependent growth of hematopoietic cells through … - Full text - MIT Libraries
S Ezoe, I Matsumura, S Nakata, K Gale, K Ishihara, … - Blood, 2002 - bloodjournal.org
... protein (CBP), PU.1, c-Myb, erythroid Kruppel-like factor (EKLF), Lmo2, and Sp1 ... promoter
is activated by Ras/Raf signaling and gp130-activated STAT3, 50 , 51 ...
Cited by 7 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov - all 5 versions »

Genetic programs regulating HSC specification, maintenance and expansion - Full text - MIT Libraries
J Lessard, A Faubert, G Sauvageau - Oncogene, 2004 - nature.com
... Lmo2 Embryonic lethality, absence of primitive erythropoiesis, presence of YS derived ...
HSCs engineered to overexpress an activated form of STAT3 (STAT3c) behave ...
Web Search - ncbi.nlm.nih.gov

The Role of Stat1 in Retinoic Acid-Induced Myelomonocytic Differentiation of Human Leukemia Cells
A DIMBERG - publications.uu.se
... of transgene mice expressing the G-CSFR mutated at the Stat3 activation site ... acute
lymphoblastic leukemia (ALL), while dysregulation of both rbtn/LMO2 and tal- 1 ...
Web Search - diva-portal.org

Stem cell bioengineering for regenerative medicine
J Audet - Expert Opinion on Biological Therapy, 2004 - dx.doi.org
... One important mecha- nism of action of gp130 signalling is to activate the transcrip-
tion factor signal transducer and activator of transcription 3 (STAT3) [33 ...
Cited by 2 - Web Search - extenza-eps.com - ashley-pub.com - ingentaconnect.com - all 9 versions »

STRUCTURAL AND FUNCTIONAL SIMILARITIES AND DIFFERENCES BETWEEN THE GPS PROTEINS - Full text - MIT Libraries
H Jafar-Nejad, HJ Bellen - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... IL-6-mediated signaling through STAT3 is involved in the proliferation of T cells
upon antigenic stimulation, and the observation that Gfi-1 physically ...
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Leukemia Cells and the Cytokine Network: Therapeutic Prospects - Full text - MIT Libraries
S Moqattash, JD Lutton - Experimental Biology and Medicine, 2004 - ebmonline.org
... mice are defective in IFN-mediated functions; STAT4 and STAT6 knockout mice show
defective responses to IL-12 and IL-4, respectively; and STAT3 plays a ...
Cited by 1 - Web Search - ebmonline.org - ebmonline.org - ncbi.nlm.nih.gov

Cross Talk between Retinoic Acid Signaling and Transcription Factor GATA-2 - Full text - MIT Libraries
S Tsuzuki, K Kitajima, T Nakano, A Glasow, A … - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... GATA factors have been shown to associate with other regulatory proteins (like Sp1,
Lmo2, CBP, other GATA factors, and PML) by virtue of the C4C4 zinc fingers ...
Cited by 1 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

Immunotherapy in multiple myeloma-possibility or probability?
SJ Harrison, G Cook - blackwell-synergy.com
... transformation in two of nine undergoing gene therapy for X-linked severe combined
immunodeficiency due to the activation of the oncogene LMO2 (Hacein-Bey ...
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Supplementary Data ‘Stemness’: Transcriptional Profiling of Embryonic and Adult Stem Cells
M Ramalho-Santos, S Yoon, Y Matsuzaki, RC Mulligan … - intl.sciencemag.org
... cycle/oncogenesis (70) eg Mapk 12/14, Mapkk3, K-Ras2, H-Ras, RhoB, All1, Fos, FosB,
Jun, JunB, Myc, N-Myc, Elf1, Ext2, Meis1, PU.1, Tal1 (Scl), Lmo2, Yes, ski ...
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Jak 3, severe combined immunodeficiency, and a new class of immunosuppressive drugs - Full text - MIT Libraries
M Pesu, F Candotti, M Husa, SR Hofmann, LD … - Immunological Reviews, 2005 - blackwell-synergy.com
... 1 ). Several Stats are activated by c cytokines including Stat1, Stat3 and Stat5;
by contrast, Stat6 is particularly important for mediating IL-4 signaling (46 ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Technical Bulletin
H Protein, H ELISA - sigmaaldrich.com
Page 1. Panorama ™ Human Protein Function Microarray Cancer v1 Technical Bulletin
Catalog Number HPFM2 HPFM2_TechBul .indd i HPFM2_TechBull.indd i ...
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Androgen Receptor Coregulators in Prostate Cancer - Full text - MIT Libraries
M Rahman, H Miyamoto, C Chang - Clinical Cancer Research, 2004 - intl-clincancerres.aacrjournals.org
... DJ, Gao AC. Interleukin-6 induces prostate cancer cell growth accompanied
by activation of stat3 signaling pathway. Prostate, 42 ...
Cited by 1 - Web Search - clincancerres.aacrjournals.org - urmc.rochester.edu - ncbi.nlm.nih.gov

Targeting Gene Therapy for Prostate Cancer
NJ Maitland, LJ Stanbridge, V Dussupt - Current Pharmaceutical Design, 2004 - ingentaconnect.com
Page 1. Current Pharmaceutical Design, 2004, 10, 531-555 531 1381-6128/04
$45.00+.00 © 2004 Bentham Science Publishers Ltd. Targeting ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Marko Pesu Fabio Candotti Matthew Husa Sigrun R. Hofmann - Full text - MIT Libraries
LD Notarangelo, JJ O’Shea - Immunological Reviews, 2005 - ingentaconnect.com
... 1). Several Stats are activated by g c cytokines including Stat1, Stat3 and Stat5;
by contrast, Stat6 is particularly important for mediating IL-4 signaling (46 ...
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Current World Literature; Bibliography
T Blake, N Adya, CH Kim… - Current Opinion in Hematology, 2001 - co-hematology.com
... Leukemia 2000, 14:1885-1891. Davenport J, Neale GAM, Goorha R: Identification
of genes potentially involved in LMO2-induced leukemogenesis. ...
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Exploitation of stem cell plasticity - Full text - MIT Libraries
E Martin-Rendon, SM Watt - Transfusion Medicine, 2003 - blackwell-synergy.com
... A novel factor, Nanog, that promotes pluripotency and self-renewal in the mouse
embryo and murine ES cells independently of the LIF/Stat3 pathway has also been ...
Cited by 4 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

Vascular Endothelial Growth Factors and the Bmx Tyrosine Kinase in the Regulation of Angiogenesis …
K Paavonen - ethesis.helsinki.fi
Page 1. Helsinki University Biomedical Dissertations No. 44 Vascular Endothelial
Growth Factors and the Bmx Tyrosine Kinase in the Regulation ...
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