Response to Wang et al. - Full text - MIT Libraries
L Weng, J Cohen, R McPherson, LA Pennacchio - J Clin Invest, 2005 - jci.org
... completely normal (Duke treadmill score, low risk; normal rest and stress ... right
ventricular hypertrophy, an abnormality noted in murine Mef2a deficiency, and ...
Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

New insights into porcine-human synteny conservation - Full text - MIT Libraries
NJ Larsen, S Marklund, KA Kelly, M Malek, CK … - Mammalian Genome, 1999 - springerlink.com
... KLK3); MADS box transcription enhancer factor 2, polypeptide A (MEF2A); retinoid
X ... ADCYAP1, ANT1, FGF7, GRIA2, GRIA3, and KLK3), while the rest were expected ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov

Bioconductor’s multtest package
S Dudoit, Y Ge - mssm.edu
... resT$rawp[ord] > maxT <- resT$adjp[ord] > teststat <- resT$teststat[ord ... Myosin light
chain (alkali)" [39] "DHPS Deoxyhypusine synthase" [40] "MEF2A gene (myocyte ...
View as HTML - Web Search - maths.lth.se - pbil.univ-lyon1.fr - inn.weizmann.ac.il - all 8 versions »

Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca 2 - Full text - MIT Libraries
EO Ojuka, TE Jones, LA Nolte, M Chen, BR Wamhoff, … - Regulation, 2002 - ajpendo.physiology.org
... dependent protein kinase (CAMK) inhibitor KN93 from Calbiochem (La Jolla, CA), MEF2A
and GLUT3 ... The rest of the reagents were purchased from Sigma Chemical. ...
Cited by 28 - Web Search - ajpendo.physiology.org - ncbi.nlm.nih.gov

This Week IN
ID Effect, F Color, M Electronics, MD Invitations, … - sciencemag.org
... fabrication lines will subject such a memory, along with the rest of the ... wide linkage
analysis identified an autosomal dominant locus that included MEF2A, an en ...
Web Search - sciencemag.org

Cloning of the novel gene TM6SF1 reveals conservation of clusters of paralogous genes between human …
L Carim-Todd, M Escarceller, X Estivill, L Sumoy, … - Cytogenetics and Cell Genetics, 2000 - content.karger.com
... peripheral blood leukocytes, while it appeared absent from the rest of tissues ...
proteoglycan core proteins with hyaluronic acid binding activity; and MEF2A (Acc ...
Cited by 3 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Exercise Increases Nuclear AMPK {alpha} 2 in Human Skeletal Muscle - Full text - MIT Libraries
SL McGee, KF Howlett, RL Starkie, D Cameron-Smith, … - Diabetes, 2003 - diabetes.diabetesjournals.org
... and reported as the means ± SEM (n = 6). *Significantly different from rest (P =
0.024 ... 2001 [Abstract/Free Full Text]; Mora S, Pessin JE: The MEF2A isoform is ...
Cited by 6 - Web Search - diabetes.diabetesjournals.org - ncbi.nlm.nih.gov

Specificity Determinants in MAPK Signaling to Transcription Factors - Full text - MIT Libraries
D Barsyte-Lovejoy, A Galanis, AD Sharrocks - J Biol Chem, 2002 - jbc.org
... of active p38 2 , a 14-fold stimulation of wild-type MEF2A was observed ... The rest
of the mutations, including residues from the basic and hydrophobic clusters ...
Cited by 19 - Web Search - dx.doi.org - ncbi.nlm.nih.gov - all 4 versions »

E00512-2001-Revision
EO Ojuka, TE Jones, LA Nolte, M Chen, BR Wamhoff, … - ajpendo.physiology.org
... 2+ is mediated by activation of CAMK, and indicate that MEF2A and MEF2D are involved
in this adaptive response. ... Louis, MO). The rest of the reagents ...
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Hepatocyte growth factor(HGF) inhibits skeletal muscle cell differentiation: A role for the bHLH … - Full text - MIT Libraries
Y Leshem, DB Spicer, R Gal-Levi, O Halevy - Journal of Cellular Physiology, 2000 - doi.wiley.com
... hu- man MEF2A but cross-react with both human and mouse MEF2A, MEF2C, and ... rest and
differentiation in the absence of HGF (Skapek et al., 1995) (data not shown ...
Cited by 16 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

[CITATION] Specificity Determinants in MAPK - Full text - MIT Libraries
DBL Dagger, AG Dagger, ADSDD Dagger - J. Biol. Chem
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Multifunctional role of Erk5 in multiple myeloma - Full text - MIT Libraries
X Carvajal-Vergara, S Tabera, JC Montero, A … - Blood, 2005 - bloodjournal.org
... 4 proteins (MEF2A, B, C, and D), 32 and 3 of them (MEF2A, C, and ... The rest of the
immunoprecipitation and Western blotting protocol was carried out as described ...
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Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors - Full text - MIT Libraries
SH Yang, A Galanis, AD Sharrocks - Mol. Cell. Biol, 1999 - mcb.asm.org
... transcription (8). In mammals, there are four MEF2C-related genes, MEF2A, MEF2B,
MEF2C ... DNA binding domains and to a lesser extent throughout the rest of the ...
Cited by 98 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Mef2 proteins, required for muscle differentiation, bind an essential site in the Ig lambda enhancer - Full text - MIT Libraries
E Satyaraj, U Storb - J. Immunol, 1998 - jimmunol.org
... Mef2A and Mef2C proteins were made by T7-directed in vitro transcription-translation ...
to determine the ß-galactosidase activity (40), and the rest was heated ...
Cited by 6 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Mef2 Proteins, Required for Muscle Differentiation, Bind an Essential Site in the Ig Enhancer
E Satyaraj, U Storb - jimmunol.org
... Mef2A and Mef2C proteins were made by T7-directed in vitro transcription ... was removed
to determine the -galactosidase activity (40), and the rest was heated to 60 ...
Web Search

UCP-mediated energy depletion in skeletal muscle increases glucose transport despite lipid … - Full text - MIT Libraries
DH Han, LA Nolte, JS Ju, T Coleman, JO Holloszy, … - Am J Physiol Endocrinol Metab, 2004 - intl-ajpendo.physiology.org
... induction of MEF2A and MEF2D, resulting in increased GLUT4 expression and enhanced ...
muscle of transgenic mice selectively affects muscles at rest and decreases ...
Cited by 3 - Web Search - intl-ajpendo.physiology.org - ncbi.nlm.nih.gov

Conservation of Brachyury, Mef 2, and Snail in the Myogenic Lineage of Jellyfish: A Connection to … - Full text - MIT Libraries
J Spring, N Yanze, C Josch, AM Middel, B Winninger … - Developmental Biology, 2002 - unibas.ch
... (B) Podocoryne Mef2 shares 92% sequence identity with human MEF2A in the MADS-box
and Mef2 domain, but little sequence similarity in the rest of the protein. ...
Cited by 30 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Simulated microgravity suppresses osteoblast phenotype, Runx 2 levels and AP-1 transactivation - Full text - MIT Libraries
C Ontiveros, LR McCabe - Journal of Cellular Biochemistry, 2003 - doi.wiley.com
... Abstract Conditions of disuse such as bed rest, space flight, and immobilization
result in decreased mechanical loading ... MEF2A ATT CAA CTC CAA TTC CTC TTC CTC ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov

Mechanisms regulating GLUT 4 glucose transporter expression and glucose transport in skeletal muscle - Full text - MIT Libraries
A Zorzano, M Palacin, A Guma - Acta Physiologica Scandinavica, 2005 - blackwell-synergy.com
... the metabolic reservoirs necessary to maintain the energetic demands during rest,
but also ... of MEF2 isoforms are expressed in skeletal muscle (MEF2A, MEF2C, and ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

ATF 1 Phosphorylation by the ERK MAPK Pathway Is Required for Epidermal Growth Factor-induced c-jun … - Full text - MIT Libraries
P Gupta, R Prywes - J Biol Chem, 2002 - jbc.org
... p38 family phosphorylates and activates MEF2A and MEF2C whereas ERK5 activates MEF2A,
MEF2C, and ... Ras then activates Raf-1 and the rest of the ERK1/2 pathway (5 ...
Cited by 10 - Web Search - columbia.edu - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

ERK (MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38 (SAPK) - Full text - MIT Libraries
JA Aguirre-Ghiso, Y Estrada, D Liu, L Ossowski - Cancer Res, 2003 - cancerres.aacrjournals.org
... Controls lacking the transactivator constructs (Elk-, CHOP-, or MEF2A-GAL4) but
including the GAL4-tk ... inoculated on CAMs (T-HEp3 at 2 x 10 5 , the rest of the ...
Cited by 39 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - all 4 versions »

Time-dependent changes in the expression of the MEF 2 transcription factor family during topographic … - Full text - MIT Libraries
I Leysen, E Van der Gucht, UT Eysel, R Huybrechts, … - European Journal of Neuroscience, 2004 - blackwell-synergy.com
... Analysis of the laminar distribution profile of MEF2A in cat striate cortex revealed ...
II, and in layer IVc, a moderate expression pattern in the rest of layer ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

A MADS box protein consensus binding site is necessary and sufficient for activation of the opaque- … - Full text - MIT Libraries
SR Lockhart, M Nguyen, T Srikantha, DR Soll - J. Bacteriol, 1998 - jb.asm.org
... binding site of Arabidopsis (17), SRF binding site of humans (35), and Mef2a binding
site ... 24 bp, between 404 and 380 bp in CROP7, which removed the rest of the ...
Cited by 14 - Web Search - pubmedcentral.nih.gov - jb.asm.org - ncbi.nlm.nih.gov

Role of histone and transcription factor acetylation in diabetes pathogenesis.
SG Gray, P De Meyts - Diabetes Metab Res Rev, 2005 - doi.wiley.com
... As NRSF/REST has been demonstrated to utilize HDACs to repress transcription [84 ...
In regenerating muscle isoforms MEF2A, C and D have been shown to transactivate ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Experimental Physiology Effect of short-term training on GLUT-4 mRNA and protein expression in human … - Full text - MIT Libraries
GN Kraniou, D Cameron-Smith, M Hargreaves - Experimental Physiology, 2004 - blackwell-synergy.com
... After a brief period of supine rest, subjects then performed their first 60 ... activation
were associated with increased expression of both the MEF2A and MEF2D ...
Web Search - ingentaconnect.com - dx.doi.org - ep.physoc.org - all 6 versions »

Fashioning the vertebrate heart: earliest embryonic decisions - Full text - MIT Libraries
MC Fishman, KR Chien - Development, 1997 - dev.biologists.org
... In mice, MEF2B and MEF2C are expressed in the precardiac mesoderm at e7.75, followed
by MEF2A and MEF2D (Edmondson et al., 1994; Molkentin et al., 1996). ...
Cited by 186 - Web Search - dev.biologists.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov

REGULATION OF THE C-JUN ENaANCER/PROMOTER BY MXF2
PD MYOGENESIS - collectionscanada.ca
... the bHLH protein myogenin can interact with MEF2A, as well as MEFZD. ... Bédard, Natalie,
and the rest of the Bédard lab for their help throughout these ...
View as HTML - Web Search

Asynchronous activation of 10 muscle‐specific protein(MSP) genes during zebrafish somitogenesis - Full text - MIT Libraries
Y Xu, J He, X Wang, TM Lim, Z Gong - Developmental Dynamics, 2000 - doi.wiley.com
... the same zebrafish gene. The rest of seven zebrafish cDNA sequences are
reported for the first time. Tissue Distribution of MSP ...
Cited by 23 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Exercise and gene expression: physiological regulation of the human genome through physical activity - Full text - MIT Libraries
FW Booth, MV Chakravarthy, EE Spangenburg - The Journal of Physiology, 2002 - blackwell-synergy.com
... into the coronary venous blood of soccer players while at rest, as compared ... in
epitrochlearis muscles or L6 myocytes increased GLUT4 as well as MEF2A and MEF2D ...
Cited by 21 - Web Search - jp.physoc.org - dx.doi.org - jphysiol.org - all 6 versions »

Classification and phylogeny of the MADS-box multigene family suggest defined roles of MADS-box gene … - Full text - MIT Libraries
G Theissen, JT Kim, H Saedler - J Mol Evol, 1996 - springerlink.com
... 1988 P11746 MEF2A Hs MEF2A Hs Homo sapiens Yu et al. 1992; Kaushal et al. 1994
S25831 MEF2A Mm MEF2A Mm Mus musculus Martin et al. 1994 U30823 ...
Cited by 139 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Genomewide Linkage Scan Identifies a Novel Susceptibility Locus for Restless Legs Syndrome on … - Full text - MIT Libraries
S Chen, WG Ondo, S Rao, L Li, Q Chen, Q Wang - The American Journal of Human Genetics, 2004 - journals.uchicago.edu
... to move the limbs with or without paresthesia; (2) worsening of symptoms at rest;
(3) at ... L, Fan C, Topol SE, Topol EJ, Wang Q (2003) Mutation of MEF2A in an ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

[CITATION] NF-B-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia - Full text - MIT Libraries
DC Guttridge, MW Mayo, LV Madrid, CY Wang, AS … - Science, 2000
Cited by 32 - Web Search

Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases … - Full text - MIT Libraries
L Genesca, A Aubareda, JJ Fuentes, X Estivill, S … - Biochem. J, 2003 - biochemj.org
... Calcineurin has been shown to enhance the DNA binding activity of MEF2A, thereby ...
proteins for each member of the family as also happens when the rest of the ...
Cited by 7 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Control of muscle bioenergetic gene expression: implications for allometric scaling relationships of … - Full text - MIT Libraries
CD Moyes, CMR LeMoine - Journal of Experimental Biology, 2005 - jeb.biologists.org
... When at rest, oxidative muscles tend to have higher levels of Ca 2+ (100-300 ... deficiency
and cardiac sudden death in mice lacking the MEF2A transcription factor ...
Web Search - biology.queensu.ca - jeb.biologists.org - ncbi.nlm.nih.gov

Anthrax lethal factor-cleavage products of mitogen-activated protein kinase (MAPK) kinases exhibit … - Full text - MIT Libraries
AJ Bardwell, M Abdollahi, L Bardwell - Biochem J, 2004 - bj.portlandpress.com
... 24]. Anthrax LF cleavage of MEK1, MEK2, MKK3, MKK4 and MKK6 detaches the
MAPK-docking site from the rest of the polypeptide. These ...
Cited by 2 - View as HTML - Web Search - biochemj.org - devcell.bio.uci.edu - dx.doi.org - all 8 versions »

Adaptive evolution in the Arabidopsis MADS-box gene family inferred from its complete resolved … - Full text - MIT Libraries
LP Martinez-Castilla, ER Alvarez-Buylla - Proc Natl Acad Sci US A, 2003 - pubmedcentral.nih.gov
... IKC structure but share conserved motifs in their MADS-boxes with the rest of the ...
16 is within the MADS-domain, and its homologous position in MEF2A plays a ...
Cited by 8 - Web Search - dx.doi.org - pnas.org - ncbi.nlm.nih.gov - all 5 versions »

Exercise, diet, and skeletal muscle gene expression
M Hargreaves, D Cameron-Smith, LL SPRIET, RM … - Med Sci Sports Exerc, 2002 - acsm-msse.org
... altered after a single exercise bout but was increased at rest and after ... The MEF2A
isoform is required for striated muscle-specific expression of the insulin ...
Cited by 6 - Web Search - aleixo.com - aleixomkt.com.br - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

Novel transcription factors in human CD34 antigen-positive hematopoietic cells - Full text - MIT Libraries
I Gomes, TT Sharma, S Edassery, N Fulton, BG Mar, … - Blood, 2002 - bloodjournal.org
... Hs.182280 MEF2A MADS box transcription enhancer factor 2, polypeptide A (myocyte
enhancer ... Hs.227630 REST RE1-silencing transcription factor 4q12-q13.3 4.3 L W ...
Cited by 3 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Deacetylase enzymes: biological functions and the use of small-molecule inhibitors - Full text - MIT Libraries
CM Grozinger, SL Schreiber - Chem. Biol, 2002 - www-schreiber.chem.harvard.edu
... Sin3 and NuRD (reviewed in [22]), whereas REST, which silences neuronal-specific
genes in non-neuronal cells yet been demonstrated for this protein [26, 27]. ...
Cited by 61 - View as HTML - Web Search - faculty.biu.ac.il - broad.mit.edu - all 8 versions »

Comparative genomics provides evidence for an ancient genome duplication event in sh
JS Taylor, Y Van de Peer, I Braasch, A Meyer - Phil. Trans. R. Soc. Lond. B, 2001 - journals.royalsoc.ac.uk
... The goal of our study was to use a phylogenetic approach to evaluate the hypothesis
that the `extra’ Hox genes and the rest of the genome in ¢shes were ...
Cited by 102 - Web Search - evolutionsbiologie.uni-konstanz.de - mit.edu - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Regulation of TNF expression by multiple mitogen-activated protein kinase pathways - Full text - MIT Libraries
W Zhu, JS Downey, J Gu, F Di Padova, H Gram, J Han - J. Immunol, 2000 - jimmunol.org
... There are a number of transcription factors, such as c-Jun, MEF2A/2C, ELK-1, serum ...
on a 43-bp sequence surrounding the TATA box rather than on the rest of the ...
Cited by 36 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

The gene orders on human chromosome 15 and chicken chromosome 10 reveal multiple inter-and … - Full text - MIT Libraries
R Crooijmans, RJM Dijkhof, T Veenendaal, JJ van … - Mol Biol Evol, 2001 - mbe.oupjournals.org
... 20 human chromosomes have remained unchanged during evolution and that the rest
have had ... is in case of linkage group 18 with the genes CYP19 and MEF2A) can be ...
Cited by 19 - Web Search - mbe.oupjournals.org - apt.allenpress.com - ncbi.nlm.nih.gov

Cytogenetic localization of 136 genes in the horse: comparative mapping with the human genome - Full text - MIT Libraries
D Milenkovic, A Oustry-Vaiman, TL Lear, A Billault … - Mammalian Genome, 2002 - springerlink.com
... 21-q11.23 G MEF2A MADS box transcription enhancer factor 2, polypeptide A
(myocyte enhancer factor 2A) 1q14-p15 15q26 G CYP19 Cytochrome ...
Cited by 20 - Web Search - uky.edu - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Silence of the Genes: A Targeted Approach to the Suppression of Specific Genes in Human Disease …
J Apostolopoulos - Current Genomics, 2003 - ingentaconnect.com
Page 1. Current Genomics, 2003, 4, 587-598 587 1389-2029/03 $41.00+.00
©2003 Bentham Science Publishers Ltd. Silence of the Genes ...
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Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions - Full text - MIT Libraries
RM Biondi, AR Nebreda - Biochem. J, 2003 - bj.portlandpress.com
... regions of the kinase is indicated in the p38α MAPK–MEF2A peptide magnification. ...
PKB: a peculiar PDK1 substrate PKB is different from the rest of the PDK1 ...
Cited by 38 - View as HTML - Web Search - biochemj.org - safar.pitt.edu - dx.doi.org - all 7 versions »

Evolutionary patterns of gene families generated in the early stage of vertebrates - Full text - MIT Libraries
Y Wang, X Gu - J. Mol. Evol, 2000 - springerlink.com
... For the rest (7 families), at least one gene duplication event had occurred before
the divergence ... forms (Mef2A, D, and C) are related to genome duplica- tion(s ...
Cited by 35 - Web Search - xgu.zool.iastate.edu - csb.yale.edu - ncbi.nlm.nih.gov - all 6 versions »

Transcriptional reprogramming and ultrastructure during atrophy and recovery of mouse soleus muscle - Full text - MIT Libraries
C Dapp, S Schmutz, H Hoppeler, M Fluck - Physiol Genomics, 2004 - physiolgenomics.physiology.org
... the proportion of type I fibers is above 80%, with the rest being IIa or ... Mean values
(per soleus) of myogenic factors (MEF2A, MEF2C, MYF6, MYOD, and MYOG) from ...
Cited by 2 - Web Search - physiolgenomics.physiology.org - ncbi.nlm.nih.gov

TOPICAL REVIEW Exercise and gene expression: physiological regulation of the human genome through …
FW Booth, MV Chakravathy, EE Spangenburg - jp.physoc.org
... added that major adaptations for human survival ‘were consonant with habitual physical
activity, including endurance and peak effort alternated with rest.’ ...
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Recent advances in the molecular diagnosis of diffuse large B-cell lymphoma
K Fu, J Iqbal, WC Chan - Expert Rev. Mol. Diagn, 2005 - future-drugs.com
... separate branches on the hierarchical cluster dendrogram) to the rest of the ABC ...
p21CIP1 RGS9 IMAGE:1340508 NFKB2 KIAA0339 ITGAM IL23A SPINT2 MEF2A PFDN5 ZNF141 ...
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Stem cells and the formation of the myocardium in the vertebrate embryo
LM Eisenberg, SW Kubalak, CA Eisenberg - The Anatomical Record, 2004 - doi.wiley.com
... While targeted disruption of these individual genes (eg, Nkx2.5, GATA4, MEF2a, MEF2c,
Bop, etc.) in knockout mice dramatically affected ... the rest of the mesoderm ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries