Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice - Full text - MIT Libraries
JJ Moskow, F Bullrich, K Huebner, IO Daar, AM … - Mol. Cell. Biol, 1995 - mcb.asm.org
... The nucleotide sequence of the two alternative forms of Meis1 has been submitted
to ... common sites of viral integration in BXH-2 myeloid tumors: c-myb and Evi2 (5 ...
Cited by 96 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires … - Full text - MIT Libraries
GG Wang, MP Pasillas, MP Kamps - Blood, 2005 - bloodjournal.org
... immortalized by Hoxa9 plus Meis1 versus 3 others immortalized by Hoxa9 alone. This
analysis considered genes expressed as low as 1/30 that of c-Myb and one ...
Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov

Myeloid Leukemia: Disease Genes and Mouse Models
BXH Mice - content.karger.com
... 14 Wolf L: Myb-induced transformation. ... 16 Moskow JJ, Bullrich F, Huebner K, Daar
IO, Buchberg AM: Meis1, a PBX1-related homeobox gene involved in myeloid ...
Web Search - content.karger.com

Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable … - Full text - MIT Libraries
KR Calvo, DB Sykes, M Pasillas, MP Kamps - Mol Cell Biol, 2000 - dx.doi.org
... Although Hoxa9 and Meis1 can bind DNA as heterodimers, both can also ... exhibited a
promyelocytic transcriptional profile, expressing PU.1, AML1, c-Myb, C/EBP ...
Cited by 33 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a … - Full text - MIT Libraries
JD Shaughnessy Jr, DA Largaespada, E Tian, CF … - Oncogene, 1999 - nature.com
... al., 1996). As expected, nearly all of the viral integrations at Myb, Hoxa7,
Hoxa9, and Meis1 loci are B-ecotropic viruses. This is ...
Cited by 9 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Application of Ingenuity Pathways Analysis to Identify Putative Biomarkers of Childhood Leukemia …
IA Spectrum - Cancer - ingenuity.com
... CHD4,Histone H3,Histone H4, MADH1, MADH4,MEIS1, MLL,PBX1, SIN3A, SMARCA2, SPP1 ... CREB1,
CREBBP,HDAC1, HDAC2,HOXA9, HOXC8, KIAA0601, MBD3,MTA2, MYB,PPIE, PPP1R15A ...
View as HTML - Web Search

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias
N Genetics - Nature Genetics, 1996 - nature.com
... Moscow, JJ, Bullrich, F., Huebner, K., Daar, IO & Buchberg, AM Meis1, a PBX1 ... AD,
Klinman, DM, Smith, HR & Mushinski, JF Autoimmunity and c-myb transcription. ...
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Drosophila in cancer research
CJ Potter, GS Turenchalk, T Xu - Trends Genet, 2000 - botany.utoronto.ca
... aurora aurora 1, aurora 2, AIM-1 gigas TSC2 cactus IB homothorax Meis1 haywire
ERCC3 costal-2 ? ... D.myb myb spellchecker hMSH2 l(2)talc ? ...
Cited by 33 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell … - Full text - MIT Libraries
T Nakamura, Y Yamazaki, Y Saiki, M Moriyama, DA … - Mol. Cell. Biol, 2000 - mcb.asm.org
... growth and differentiation factor, Myb (myeloblastosis oncogene); three homeobox
genes, Hoxa7 (homeobox A7), Hoxa9 (homeobox A9), and Meis1 (myeloid ecotropic ...
Cited by 15 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Activation of the Rap 1 Guanine Nucleotide Exchange Gene, CalDAG-GEF I, in BXH-2 Murine Myeloid … - Full text - MIT Libraries
AJ Dupuy, K Morgan, FC von Lintig, H Shen, H Acar, … - J Biol Chem, 2001 - jbc.org
... myeloblastosis oncogene (Myb); three homeobox genes, homeobox A7 (Hoxa7), homeobox
A9 (Hoxa9), and myeloid ecotropic viral integration site 1 (Meis1); a zinc ...
Cited by 12 - Web Search - dx.doi.org - intl.jbc.org - ncbi.nlm.nih.gov - all 6 versions »

A Set of Hox Proteins Interact with the Maf Oncoprotein to Inhibit Its DNA Binding, Transactivation, … - Full text - MIT Libraries
K Kataoka, K Yoshitomo-Nakagawa, S Shioda, M … - J Biol Chem, 2001 - jbc.org
... with the Hox proteins, while a distantly related Hox family member, Meis1, could
not ... case of c-Maf, interaction with the proto-oncogene product c-Myb was found ...
Cited by 22 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Estrogen-regulated Conditional Oncoproteins: Tools to Address Open Questions in Normal Myeloid Cell …
DB Sykes, MP Kamps - Leukemia & Lymphoma, 2003 - dx.doi.org
... to that induced by retroviral co-expression of Hoxa9 and Meis1”, Oncogene 21 ... G.,
Kreider, B., Rovera, G. and Reddy, EP (1993) “v-myb blocks granulocyte ...
Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Evi27 encodes a novel membrane protein with homology to the IL17 - Full text - MIT Libraries
J D Shaughnessy Jr - Oncogene, 2000 - nature.com
... myeloblastosis oncogene (Myb); three homeobox genes, homeobox A7 (Hoxa7), homeobox
A9 (Hoxa9), and myeloid ecotropic viral integration site 1 (Meis1); a zinc ...
Web Search

Retroviral integration at the Epi1 locus cooperates with Nf1 gene loss in the progression to acute … - Full text - MIT Libraries
SM Blaydes, SC Kogan, BT Truong, DJ Gilbert, NA … - J. Virol, 2001 - jvi.asm.org
... up-regulation of a c-myb transgene. Mol. Cell. Biol. 10:705-710[Medline]. 25. Moscow,
JJ, F. Bullrich, K. Huebner, IO Daar, and AM Buchberg. 1995. Meis1, a PBX1 ...
Cited by 8 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements - Full text - MIT Libraries
T Rozovskaia, O Ravid-Amir, S Tillib, G Getz, E … - Proceedings of the National Academy of Sciences, 2003 - pnas.org
... This includes activation of oncogenes (MYC, HOX A9 and MEIS1, LMO2, etc.), inactivation
of ... of genes involved in cell proliferation (eg, cyclin A1 and myb-like 2 ...
Cited by 23 - Web Search - 171.66.122.165 - santafe.edu - weizmann.ac.il - all 10 versions »

Retroviral insertional mutagenesis identifies oncogene cooperation. - Full text - MIT Libraries
T Nakamura - Cancer Science, 2005 - blackwell-synergy.com
... (4,5) In approximately 10% of BXH2 leukemias we identified overlapping
of retroviral integrations in Meis1 and Hoxa7/a9 loci. (11 ...
Web Search - ncbi.nlm.nih.gov

Development of leaf shape
M Byrne, M Timmermans, C Kidner, R Martienssen - Curr. Opin. Plant Biol, 2001 - biology.ed.ac.uk
... PHAN is a myb-domain transcription factor that is expressed in lateral ... class three
amino-acid extension (TALE)-homeobox genes homothorax/Meis1 induces the ...
Cited by 30 - View as HTML - Web Search - jic.ac.uk - jic.bbsrc.ac.uk - all 4 versions »

E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause … - Full text - MIT Libraries
DB Sykes, MP Kamps - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... throughout their differentiation (E2A (3, 14), Ikaros (15), PU.1, c-Myb, and Egr2
(2 ... E2a/Pbx1 and SCF for pro-T-cell proliferation or between Meis1 and SCF for ...
Cited by 4 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Genetic programs regulating HSC specification, maintenance and expansion - Full text - MIT Libraries
J Lessard, A Faubert, G Sauvageau - Oncogene, 2004 - nature.com
... C-Myb Embryonic lethality, primitive hematopoiesis normal, impaired fetal liver ... Meis1
Embryonic lethality, absence of megakaryocytes, reduced fetal liver CFCs ...
Web Search - ncbi.nlm.nih.gov

Research Paper Routine expression profiling of microarray gene signatures in acute leukaemia by real … - Full text - MIT Libraries
E Sakhinia, M Faranghpour, JAL Yin, G Brady, JA … - British Journal of Haematology, 2005 - blackwell-synergy.com
... Specifically, c-MYB (P 0·04) was significantly increased in ALL in the total fraction,
whilst HOXA9 (P 0·19) and cystatin c (P 0·01) were increased in AML ...
Web Search

Luciferase Reporters: Less is More
A Paguio, B Almond, F Fan, P Stecha, D Garvin, M … - promega.com
... B-cell B-cell EBV FOXL1 CPBP EG3 MOK-2 NFAT RFX1 STAT5 MMC c-Myb MEIS1 MEIS1 C2HC1
Mus MyT1 MIBP-1 v-Myb Neu-r Neu-r NKX3.1 NKX3.1 c-Myb v-Myb HOX RFX1 TATA ...
Web Search

Control of Self-Renewal and Differentiation of Hematopoietic Stem Cells: HOXB4 on the Threshold - Full text - MIT Libraries
H KLUMP, B SCHIEDLMEIER, C BAUM - Ann. NY Acad. Sci, 2005 - annalsnyas.org
... stages of haemopoiesis is dependent on distinct threshold levels of c-Myb. ... Differential
expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout ...
Web Search - annalsnyas.org - ncbi.nlm.nih.gov

Transcriptional profile analysis of in vivo adult subventricular zone (SVZ) neurogenesis
DA Lim, M Suarez-Farinas, F Naef, C Hacker, B Menn … - asterion.rockefeller.edu
... oncogenic roles including Klf5, Tle1, Myb, Pou3f4, and Meis1/2. Chromatin-remodeling
genes Mll, Bmi1, Smarcad1, Baf53a, Hmgb2, and Hmgb3 were also identified. ...
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Oncogene activation in myeloid leukemias by Graffi murine leukemia virus proviral integration - Full text - MIT Libraries
C Denicourt, E Edouard, E Rassart - J Virol, 1999 - jvi.asm.org
... Structural organization and nucleotide sequence of the mouse c-myb oncogene. ... Meis1,
a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. ...
Cited by 9 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

pGL3 Luciferase Reporter Vectors
I Description, IIIP Components, IVC Methods, I … - promega.com
... B-cell B-cell EBV FOXL1 CPBP EG3 MOK-2 NFAT RFX1 STAT5 MMC c-Myb MEIS1 MEIS1 C2HC1
Mus MyT1 MIBP-1 v-Myb Neu-r Neu-r NKX3.1 NKX3.1 c-Myb v-Myb HOX RFX1 TATA ...
Web Search - genomics.sbg.ac.at - sci.sdsu.edu - shpromega.cn - all 8 versions »

Transcriptional Profiling During the Early Differentiation of Granulocyte and Monocyte Progenitors …
DB Sykes, J Scheele, M Pasillas, MP Kamps - Leukemia & Lymphoma, 2003 - dx.doi.org
... E2a–Pbx1 can heterodimerize with Hox proteins but cannot heterodimerize with Meis1
because the ... factors important in myeloid cell function (CBFb, c-Myb, c/EBPa ...
Cited by 2 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

HOX and Non-HOX Homeobox Genes in Leukemic Hematopoiesis - Full text - MIT Libraries
BM Owens, RG Hawley - Stem Cells, 2002 - stemcells.alphamedpress.org
... contribute to leukemia development in the case of HOXA7/9 and MEIS1 [48, 49 ... GBX2
has also been identified as a downstream target of the Myb oncogene; therefore ...
Cited by 32 - Web Search - stemcells.alphamedpress.org - dx.doi.org - ncbi.nlm.nih.gov

Estrogen-dependent E2a/Pbx1 myeloid cell lines exhibit conditional differentiation that can be … - Full text - MIT Libraries
DB Sykes, MP Kamps - Blood, 2001 - bloodjournal.org
... or c/EBP gene expression, or by maintaining high levels of c-Myb, which has ... Furthermore,
expression of Meis1, Meis2, and Meis3 was not detected in the myeloid ...
Cited by 10 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov - all 5 versions »

The role of homeobox genes in hematopoiesis
MC Magli - Biotherapy, 1998 - ingentaconnect.com
... view is supported by the finding that the human homologues of Meis1, Meis2 and ... might
be mediated by nuclear proto- oncogenes (c-myc, c-myb), or, alternatively ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genomic screen for genes involved in mammalian craniofacial development - Full text - MIT Libraries
LF Fowles, JS Bennetts, JL Berkman, E Williams, P … - genesis, 2003 - doi.wiley.com
... midkine, CRABPI), and a number of HMG and homeodomain proteins (Dlx1, Dlx5, Meis1). ...
1 U33197 Y-box binding protein (mYB-1b) R Cold shock protein domain *R ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Programme at a glance
G DINNER - anr2004.org
... 155.1 MEIS1 functions as a neuroblastoma oncogene Dirk Geerts, Nathalie Schilderink ...
immune stimulatory effect synergising with an anti-c-myb effect Chiara ...
View as HTML - Web Search - blackwell-synergy.com - ingentaconnect.com

I. I ntroduction
IV References - promega.com
... v-Myb v-Myb v-Myb PAX2/5/8 c-Myb C-Myb c-Myb c-Myb v-Myb v-Myb Pbx1/Meis1 RFX1 TATA
Brn3 CHOP CCAAT CCAAT CCAAT VIS1 CDE/CHR Smad4 Se-CtRNA ST/TA ST/TA ST/TA ...
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The Kinetic Status of Hematopoietic Stem Cell Subpopulations Underlies a Differential Expression of … - Full text - MIT Libraries
R Manfredini, R Zini, S Salati, M Siena, E … - Stem Cells, 2005 - stemcells.alphamedpress.org
... some cell cycle–related genes, such as NFY and c-myb, which regulate ... 5A ). Among
them, HOXA5, HOXA9, HOXA10, HOXB2, HOXB5, Meis1, and PBX2 are preferentially ...
Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov

Ethidium Bromide Provides a Simple Tool for Identifying Genuine DNA-Independent Associations - Full text - MIT Libraries
J Lai, W Herr - Proceedings of the National Academy of Sciences - pnas.org
... Biol. Home page WF Shen, S. Rozenfeld, A. Kwong, LG Komuves, HJ Lawrence, and C.
Largman HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid Cells Mol. ...
Web Search - adsabs.harvard.edu

Large scale molecular analysis identifies genes with altered expression in salivary adenoid cystic … - Full text - MIT Libraries
HF Frierson, AK El-Naggar, JB Welsh, LM Sapinoso, … - Am J Pathol, 2002 - ajp.amjpathol.org
... Known genes that were the most specific for ACC relative to the other car-
cinomas included versican, TGF- type III receptor, and c-myb. ...
Cited by 13 - Web Search - ajp.amjpathol.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Sox4 blocks cytokine-induced differentiation of 32Dcl3 cells and is a possible cooperating partner …
KE Boyd, A Poholek, O Mironenko, NG Copeland, NA … - yalepath.org
... factors including cMyb, Hoxa9, Hoxa7, Fli1, Meis1, and Evi1 8-12 . ... leukemia 38 .
Similarly, it has been shown that Hoxa9 and Meis1, which were identified as ...
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Identification of Cis-Element Regulating Expression of the Mouse Fgf10 Gene during Inner Ear …
H Ohuchi, A Yasue, K Ono, S Sasaoka, S Tomonari, A … - Key words, 2005 - doi.wiley.com
Page 1. PATTERNS & PHENOTYPES Identification of Cis-Element Regulating Expression
of the Mouse Fgf10 Gene during Inner Ear Development ...
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Interaction of AF 4 wild-type and AF 4· MLL fusion protein with SIAH proteins: indication for t (4; … - Full text - MIT Libraries
A Bursen, S Moritz, A Gaussmann, S Moritz, T … - Oncogene, 2004 - nature.com
... although in some of these experimental systems Hoxa7, Hoxa9 and Meis1 are
transcriptionally ... N-CoR (Zhang et al., 1998), and the c-Myb protein (Tanikawa et ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Serial analysis of gene expression (SAGE): application in cancer research - Full text - MIT Libraries
R Tuteja, N Tuteja - Med Sci Monit, 2004 - medscimonit.com
... In contrast, the presence of PGP9.5 and B-myb was much less frequent ... with the other
amplified genes MYCN, neuroblastoma amplified gene, and MEIS1, which sugge ...
Cited by 3 - View as HTML - Web Search - medscimonit.com - ncbi.nlm.nih.gov

TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... 497 Gerd A. Blobel V. ONCOGENESIS AND HEMATOPOIESIS 519 29 The Roles of the
c-myc and c-myb Oncogenes in Hematopoiesis and Leukemogenesis 521 ...
Web Search

Microarrays as Cancer Keys: An Array of Possibilities - Full text - MIT Libraries
S Mohr, GD Leikauf, G Keith, BH Rihn - Journal of Clinical Oncology, 2002 - jco.org
... Full Text]; Kauraniemi P, Hedenfalk I, Persson K, et al: MYB oncogene amplification
in ... Rozovskaia T, Feinstein E, Mor O, et al: Upregulation of Meis1 and HoxA9 ...
Cited by 30 - Web Search - dx.doi.org - jco.org - ncbi.nlm.nih.gov - all 5 versions »

Transcript map of the 3.7-Mb D19S112-D19S246 candidate tumor suppressor region on the long arm of … - Full text - MIT Libraries
C Hartmann, L Johnk, G Kitange, Y Wu, LK Ashworth, … - Cancer Res, 2002 - cancerres.aacrjournals.org
... Interestingly, the highly similar family member Meis1 was isolated as a common site ...
centromeric to the 150-kb small deletion region, containing a Myb-like DNA ...
Cited by 10 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

THE ROLE OF KNOX GENES IN PLANT DEVELOPMENT# - Full text - MIT Libraries
S Hake, HMS Smith, H Holtan, E Magnani, G Mele, J … - Annual Review of Cell and Developmental Biology, 2004 - arjournals.annualreviews.org
... A negative regulator found in different species is a MYB transcription factor called
ROUGH SHEATH2 (RS2) in maize, ASSYMETRIC LEAVES1 (AS1) in Arabidopsis, and ...
Cited by 5 - Web Search - nutr.annualreviews.org - nutr.annualreviews.org - ncbi.nlm.nih.gov - all 5 versions »

Gene Expression Profile in AML Gene expression profile reveals deregulation of genes with relevant …
NC Gutierrez, R Lopez-Perez, JM Hernandez, I … - Leukemia, 2005 - nature.com
... L, Blasi F & Sauvageau G. Defining roles for HOX and MEIS1 genes in ... Myeloblastin
is an Myb target gene: mechanisms of regulation in myeloid leukemia cells ...
Web Search - nature.com

Gene expression profile reveals deregulation of genes with relevant functions in the different …
S Salamanca-CSIC - Leukemia, 2005 - nature.com
... Members of HOX family (A5, A6, A7, A9, A10, B2, B5 and B7) and the TALE proteins
(MEIS1 and PBX3) were jointly overexpressed in non-APL leukemias. ...
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Knots in the family tree: evolutionary relationships and functions of knox homeobox genes
L Reiser, P Sanchez-Baracaldo, S Hake - Plant Mol. Biol, 2000 - springerlink.com
... X92392), KNAT4 (A. thaliana, X92393), KNAT5 (A. thaliana, X92394), Mrg1a (Mus musculus,
U68383), CEH-25 (Caenorhabditis elegans, AJ000533), X-Meis1-3 (Xenopus ...
Cited by 65 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to … - Full text - MIT Libraries
A Yokoyama, Z Wang, J Wysocka, M Sanyal, DJ … - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... J. Manak for generously providing a rabbit polyclonal anti-Drosophila Myb antibody,
P ... Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 ...
Cited by 16 - Web Search - dx.doi.org - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Animal models of acute myelogenous leukaemia– development, application and future perspectives
E Mc Cormack, O Bruserud, BT Gjertsen - Leukemia, 2005 - nature.com
... disease induction in chickens, lead to the discovery of the v-myb oncogene ... Co-expression
and interaction of NUP98−HOX9 with Meis1 has been shown to accelerate ...
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Identification of a Hoxd10-regulated transcriptional network and combinatorial interactions with … - Full text - MIT Libraries
E Hedlund, SL Karsten, L Kudo, DH Geschwind, EM … - Journal of Neuroscience Research, 2004 - doi.wiley.com
Page 1. Identification of a Hoxd10-Regulated Transcriptional Network and
Combinatorial Interactions With Hoxa10 During Spinal Cord Development ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Class Discovery in Acute Lymphoblastic Leukemia using Gene Expression Analysis
U Einav, U Einav, PEDPE Domany, PEDPE Domany - 2003 - weizmann.ac.il
Page 1. Class Discovery in Acute Lymphoblastic Leukemia using Gene Expression
Analysis Uri Einav Uri Einav Uri Einav Uri Einav M.Sc. ...
Cited by 1 - View as HTML - Web Search - weizmann.ac.il