The homeobox gene MEIS1 is amplified in IMR-32 and highly expressed in other neuroblastoma cell … - Full text - MIT Libraries
TA Jones, RH Flomen, G Senger, D Nizetic, D Sheer - Eur J Cancer, 2000 - ncbi.nlm.nih.gov
... High expression of MEIS1 without amplification was also found in other neuroblastoma
cell lines, with and without MYCN amplification, and in medulloblastoma ...
Cited by 14 - Web Search - ncbi.nlm.nih.gov

… profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma - Full text - MIT Libraries
QR Chen, S Bilke, J Wei, C Whiteford, N Cenacchi, … - BMC Genomics, 2004 - biomedcentral.com
... clone: 241343), NCYM, and MYCN. We identified 9 previously reported co-amplified
genes (HPCAL1, ODC1, NSE1, NAG, DDX1, NCYM, POMC, DNMT3A, ALK, MEIS1, TEM8) [16 ...
Cited by 4 - Cached - Web Search - dx.doi.org - pubmedcentral.nih.gov - citebase.eprints.org - all 7 versions »

A 17 p 11. 2 germline deletion in a patient with Smith-Magenis syndrome and neuroblastoma - Full text - MIT Libraries
T Hienonen, H Sammalkorpi, P Isohanni, R Versteeg, … - Journal of Medical Genetics, 2005 - jmg.bmjjournals.com
... More specifically, we studied the pathways of MYCN and Meis1, which are amplified
in a subset of neuroblastomas, 12, 13 and of TrkA, the expression of which is ...
Web Search - jmedgenet.com - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Characterization of the gene expression profile of neuroblastoma cell line IMR-5 using serial … - Full text - MIT Libraries
M FISCHER, F BERTHOLD - Cancer Lett, 2003 - ingentaconnect.com
... amplified gene DDX1 were conspicuously overrepresented in comparison to the other
amplified genes MYCN, neuroblastoma amplified gene and MEIS1, which suggests ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Chromosomal localization of DNA amplifications in neuroblastoma tumors using cDNA microarray …
B Beheshti, I Braude, P Marrano, P Thorner, M … - Neoplasia, 2003 - ingentaconnect.com
... Chromosome CGH of IMR32 showed expected MYCN amplification at 2p24, with an ... to determine
that the gene amplification at 2p15 corresponded to MEIS1, which was ...
Cited by 27 - Web Search - jamesbirrell.ca - individual.utoronto.ca - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of … - Full text - MIT Libraries
K De Preter, F Pattyn, G Berx, K Strumane, B … - BMC Genomics, 2004 - biomedcentral.com
... Using FISH analysis, it was demonstrated that the MYCN, DDX1, NAG, MEIS1, NSE1 and
TEM8 genes and the g10d12 clone are present as multiple copies on all 3 ...
Cited by 1 - Cached - Web Search - dx.doi.org - pubmedcentral.nih.gov - citebase.eprints.org - all 11 versions »

The Phox2B homeobox gene is mutated in sporadic neuroblastomas - Full text - MIT Libraries
V van Limpt, A Schramm, A Lakeman, P van Sluis, A … - Oncogene, 2004 - nature.com
... MYCN is amplified in 20% of tumours, while amplifications of Cyclin D1, MDM2, Cdk4
and Meis1 were reported for only a few cases (Brodeur et al., 1984; Schwab ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

BMC Genomics - Full text - MIT Libraries
K De Preter, F Pattyn, G Berx, K Strumane, B … - BMC Genomics, 2004 - biomedcentral.com
... Using FISH analysis, it was demonstrated that the MYCN, DDX1, NAG, MEIS1, NSE1 and
TEM8 genes and the g10d12 clone are present as multiple copies on all 3 ...
View as HTML - Web Search - bmc.ub.uni-potsdam.de - cbgate.ugent.be - archive.ugent.be

Neuroblastoma tumour genetics: clinical and biological aspects - Full text - MIT Libraries
N Bown - J Clin Pathol, 2001 - jcp.bmjjournals.com
... both MYCN and sequences derived from other sites—for example, MYCN plus MDM2 in
the 12q hsr of the LS cell line, 65 or MYCN plus the MEIS1 homeobox gene from ...
Cited by 25 - Web Search - doccancers.info - doccancers.info - ncbi.nlm.nih.gov - all 6 versions »

Neuroblastoma: biological insights into a clinical enigma - Full text - MIT Libraries
GM Brodeur - Nature Reviews Cancer, 2003 - nature.com
... Nature 305, 245-248 (1983). Reports the cloning of the MYCN proto-oncogene as the
gene amplified in neuroblastoma cell lines and a primary tumour. ...
Cited by 95 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

BMC Genomics - Full text - MIT Libraries
QR Chen, S Bilke, JS Wei, CC Whiteford, N Cenacchi … - BMC Genomics, 2004 - biomedcentral.com
... clone: 241343), NCYM, and MYCN. We identified 9 previously reported co-amplified
genes (HPCAL1, ODC1, NSE1, NAG, DDX1, NCYM, POMC, DNMT3A, ALK, MEIS1, TEM8) [16 ...
Cited by 3 - View as HTML - Web Search - bmc.ub.uni-potsdam.de - ccr.cancer.gov - bioinformatics.med.yale.edu - all 6 versions »

High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
YP Mosse, J Greshock, A Margolin, T Naylor, K Cole … - GENES, CHROMOSOMES & CANCER, 2005 - doi.wiley.com
... genomic hybridization (aCGH) to measure genomic copy number alterations (CNAs) in
42 neuroblastoma cell lines with known 1p36.3, 2p24 (MYCN), 11q23, and ... MYCN ...
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Oligonucleotide microarray analysis of gene expression in neuroblastoma displaying loss of … - Full text - MIT Libraries
L McArdle, M McDermott, R Purcell, D Grehan, A O' … - Carcinogenesis, 2004 - carcin.oupjournals.org
... that MYCN enhances the expression of a number of genes involved with protein synthesis
(10), while other SAGE studies have revealed that the MEIS1 oncogene is ...
Cited by 1 - Web Search - bioinf.ucd.ie - ingentaconnect.com - peo.cshl.org - all 8 versions »

Clustering of Gene Hypermethylation Associated With Clinical Risk Groups in Neuroblastoma - Full text - MIT Libraries
M Alaminos, V Davalos, NKV Cheung, WL Gerald, M … - Journal of the National Cancer Institute, 2004 - jncicancerspectrum.oupjournals.org
... Results: Clustering of neuroblastoma cell lines on the basis of hypermethylation
distinguished lines with MYCN amplification (a negative prognostic factor ...
Cited by 5 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Microarray CGH
B Beheshti, PC Park, I Braude, JA Squire, JA … - Methods Mol Biol, 2002 - individual.utoronto.ca
... In this study, the MYCN (chromosome ... In the cell line IMR32, cDNA array CGH confirmed
a recently described co-amplified oncogene, MEIS1 (15,16). ...
Cited by 13 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in …
N Van Roy, H Van Limbergen, J Vandesompele, M Van … - Genes Chromosomes and Cancer, 2001 - doi.wiley.com
... BAC clones RPCI 11 89G16 (2p16), RPCI 11 444B4 for the MEIS1 gene (2p14 ... was mapped
using cosmid clones selected from a cosmid contig covering the MYCN gene: cN7 ...
Cited by 14 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Serial analysis of gene expression (SAGE): application in cancer research - Full text - MIT Libraries
R Tuteja, N Tuteja - Med Sci Monit, 2004 - medscimonit.com
... the amplified gene DDX1 were conspicuously over-repre- sented compared with the
other amplified genes MYCN, neuroblastoma amplified gene, and MEIS1, which sugge ...
Cited by 3 - View as HTML - Web Search - medscimonit.com - ncbi.nlm.nih.gov

Programme at a glance
G DINNER - anr2004.org
... 155.1 MEIS1 functions as a neuroblastoma oncogene Dirk Geerts, Nathalie Schilderink ...
identifies genomic alterations specific to stage and MYCN-amplification in ...
View as HTML - Web Search - blackwell-synergy.com - ingentaconnect.com

Spontaneously immortalized human T lymphocytes develop gain of chromosomal region 2 p 13-24 as an …
JK Siwicki, M Berglund, J Rygier, B Pienkowska- … - Genes Chromosomes and Cancer, 2004 - doi.wiley.com
... 16 and 2p23–25, contained known genes promoting cell-cycle pro- gression, such as
REL (2p12–13), MYCN (2p24.1), ALK (2p23.1), ID2 (2p25), and MEIS1 (2p14). ...
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Expression profiling of lineage differentiation in pluripotential human embryonal carcinoma cells - Full text - MIT Libraries
J Houldsworth, SC Heath, GJ Bosl, L Studer, RS … - Cell Growth Differ, 2002 - cgd.aacrjournals.org
... be either down-regulated during the differentiation program (CCND1 and MYCN), or
up ... levels of other homeobox-containing genes were identified [MEIS1, MRG1, and ...
Cited by 6 - Web Search - cgd.aacrjournals.org - ncbi.nlm.nih.gov

Gene Expression Profiling of Adult Acute Myeloid Leukemia Identifies Novel Biologic Clusters for …
CS Wilson, GS Davidson, SB Martin, E Andries, Y Xu … - hsc.unm.edu
... MEIS1 ... however, the HOX genes play the central role while MEIS1 primarily
accelerates the occurrence of leukemia once established. ...
View as HTML - Web Search - hsc.unm.edu