Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice - Full text - MIT Libraries
JJ Moskow, F Bullrich, K Huebner, IO Daar, AM … - Mol. Cell. Biol, 1995 - mcb.asm.org
... Omgp, located within intron 27b of the neurofibromatosis type 1 (Nf1) gene (33 ... common
site of viral integration in BXH-2 tumors termed Meis1 (myeloid ecotropic ...
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Retroviral integration at the Epi1 locus cooperates with Nf1 gene loss in the progression to acute … - Full text - MIT Libraries
SM Blaydes, SC Kogan, BT Truong, DJ Gilbert, NA … - J. Virol, 2001 - jvi.asm.org
... Nf1 deficiency causes Ras-mediated granulocyte/macrophage stimulating factor
hypersensitivity ... Meis1, a PBX1-related homeobox gene involved in myeloid leukemia ...
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Myeloid Leukemia: Disease Genes and Mouse Models
BXH Mice - content.karger.com
... Lange BJ, Freedamn MH, McCormick F, Jacks T, Shannon K: Loss of NF1 results in ... 16
Moskow JJ, Bullrich F, Huebner K, Daar IO, Buchberg AM: Meis1, a PBX1-related ...
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Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias
N Genetics - Nature Genetics, 1996 - nature.com
... ChemPort |; Largaespada, DA, Brannan, CI, Jenkins, NA & Copeland, NG Nf1 deficiency
causes ... JJ, Bullrich, F., Huebner, K., Daar, IO & Buchberg, AM Meis1, a PBX1 ...
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Evi27 encodes a novel membrane protein with homology to the IL17 - Full text - MIT Libraries
J D Shaughnessy Jr - Oncogene, 2000 - nature.com
... homeobox A9 (Hoxa9), and myeloid ecotropic viral integration site 1 (Meis1); a zinc ...
the genes are proven or suspected human disease genes: EVI1, NF1 and HOXA9 ...
Web Search

Drosophila in cancer research
CJ Potter, GS Turenchalk, T Xu - Trends Genet, 2000 - botany.utoronto.ca
... aurora aurora 1, aurora 2, AIM-1 gigas TSC2 cactus IB homothorax Meis1 haywire ERCC3
costal-2 ? ... dorsal NF- B/Rel family D.NF1 NF1 lats Lats1, Lats2 ...
Cited by 33 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a … - Full text - MIT Libraries
JD Shaughnessy Jr, DA Largaespada, E Tian, CF … - Oncogene, 1999 - nature.com
... all of the viral integrations at Myb, Hoxa7, Hoxa9, and Meis1 loci are B-ecotropic
viruses. This is not the case, however, for the viruses located at Nf1. ...
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TABLE
AECLF BSMC - ajrcmb.org
... Airway Epithelial Cells, Lung Fibroblasts, BSMC. OTF2, 7.3, Ring 4, 2.5, MEIS1,
5.9. Heat shock factor 4, 3.8, ZNF76, 2.5, alg-4, 4.8. ... NSCL-2, 2.3. NF1, 2.1. ZNF143 ...
Web Search

Activation of the Rap 1 Guanine Nucleotide Exchange Gene, CalDAG-GEF I, in BXH-2 Murine Myeloid … - Full text - MIT Libraries
AJ Dupuy, K Morgan, FC von Lintig, H Shen, H Acar, … - J Biol Chem, 2001 - jbc.org
... They include a tumor suppressor gene, Neurofibromatosis type 1 (Nf1); a gene with ...
A9 (Hoxa9), and myeloid ecotropic viral integration site 1 (Meis1); a zinc ...
Cited by 12 - Web Search - dx.doi.org - intl.jbc.org - ncbi.nlm.nih.gov - all 6 versions »

Making Better Drugs for Children with Cancer
PC Adamson, SL Weiner, JV Simone - ipcr.us
... TEL-AML1 <2,500 AML-ETO MLL (HOXA9, Meis1) Juvenile myelomonocytic leukemia Somatic
PTPN11 mutations NF1 GM-CSF hypersensitivity Overactivation of SHP ...
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Blood First Edition Paper, prepublished online August 1, 2002; DOI 10.1182/blood-2002-04-1244
W Count - bloodjournal.org
... 5. Thorsteinsdottir U, Kroon E, Jerome L, Blasi F, Sauvageau G. Defining roles for
HOX and MEIS1 genes in induction of acute myeloid leukemia. ... Nf1 deficiency ...
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Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell … - Full text - MIT Libraries
T Nakamura, Y Yamazaki, Y Saiki, M Moriyama, DA … - Mol. Cell. Biol, 2000 - mcb.asm.org
... They include a tumor suppressor gene, Nf1 (neurofibromatosis type 1); a gene with ...
genes, Hoxa7 (homeobox A7), Hoxa9 (homeobox A9), and Meis1 (myeloid ecotropic ...
Cited by 15 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Oncogenic interaction between BCR-ABL and NUP98-HOXA9 demonstrated by the use of an in vitro purging … - Full text - MIT Libraries
N Mayotte, DC Roy, J Yao, E Kroon, G Sauvageau - Blood, 2002 - bloodjournal.org
... F, Sauvageau G. Defining roles for HOX and MEIS1 genes in ... Nf1 deficiency causes
Ras-mediated granulocyte/macrophage colony stimulating 7factor hypersensitivity ...
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Neuroblastoma: biological insights into a clinical enigma - Full text - MIT Libraries
GM Brodeur - Nature Reviews Cancer, 2003 - nature.com
... Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome
1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers ...
Cited by 95 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
YP Mosse, J Greshock, A Margolin, T Naylor, K Cole … - GENES, CHROMOSOMES & CANCER, 2005 - doi.wiley.com
... Homozygous deletions appear to be exceedingly rare in this tumor, with CDKN2A or
NF1 biallelic deletion identified in very few cases (Martinsson et al., 1997 ...
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Sox4 blocks cytokine-induced differentiation of 32Dcl3 cells and is a possible cooperating partner …
KE Boyd, A Poholek, O Mironenko, NG Copeland, NA … - yalepath.org
... and IL-3 3-5 ), growth factor receptors (c-fms 6 ), signaling molecules (Nf1 7 ),
and transcription factors including cMyb, Hoxa9, Hoxa7, Fli1, Meis1, and Evi1 ...
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Retroviral insertions in Evi12, a novel common virus integration site upstream of Tra1/Grp94, … - Full text - MIT Libraries
PJ Valk, Y Vankan, M Joosten, NA Jenkins, NG … - J Virol, 1999 - jvi.asm.org
... 1995. Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2
mice ... Loss of the normal NF1 allele from the bone marrow of children with type 1 ...
Cited by 15 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

Bone marrow reconstitution as a relevant model of genetically programmed leukemia.
A Dolnikov, S Shen, T Passioura, G Symonds - Curr Med Chem Cardiovasc Hematol Agents, 2003 - ingentaconnect.com
... of the HoxA9 gene with some other genes such as Meis1, E2A-PBX1 NUP98 ... It was recently
shown that mice transplanted with hematopoietic cells from NF1-null mice ...
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Neuroblastoma tumour genetics: clinical and biological aspects - Full text - MIT Libraries
N Bown - J Clin Pathol, 2001 - jcp.bmjjournals.com
... both MYCN and sequences derived from other sites—for example, MYCN plus MDM2 in
the 12q hsr of the LS cell line, 65 or MYCN plus the MEIS1 homeobox gene from ...
Cited by 25 - Web Search - doccancers.info - doccancers.info - ncbi.nlm.nih.gov - all 6 versions »

The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene … - Full text - MIT Libraries
SJ Erkeland, M Valkhof, C Heijmans-Antonissen, R … - Blood, 2003 - bloodjournal.org
... demonstrated to be involved in MuLV-induced leukemias (eg, Notch-1, Nf1, p53,
Fli-1 ... E, Jerome L, Blasi F, Sauvageau G. Defining roles for HOX and MEIS1 genes in ...
Cited by 9 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Animal models of acute myelogenous leukaemia– development, application and future perspectives
E Mc Cormack, O Bruserud, BT Gjertsen - Leukemia, 2005 - nature.com
... and interaction of NUP98−HOX9 with Meis1 has been shown to accelerate disease
progression. 113 Finally, patients exhibiting mutations in the Nf1 45, 87, 114 ...
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STRUCTURE FUNCTION STUDIES OF AKR, A HOMEODOMAIN REPRESSOR OF APOVLDLII GENE EXPRESSION
ML Tejada - geocities.com
... AKR is grouped together with the Meis1 and Prep1 homeodomain proteins on the basis
of their structural ... factors Sp1 and CTF/NF1, respectively [59; 60]. Page 16. ...
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Cloning and characterization of a 5'regulatory region of the PRAP/17 {beta} HSD7 gene - Full text - MIT Libraries
M Risk, A Shehu, J Mao, CO Stocco, LT Goldsmith, … - Endocrinology, 2005 - endo.endojournals.org
... (C/EBPs), nuclear factor 1 (NF1), CCAAT displacement protein (CDP) and CCAAT
binding 23 protein/ nuclear factor Y (CBP/NF-Y) [35-37]. ...
Web Search - dx.doi.org - endo.endojournals.org - ncbi.nlm.nih.gov

The Molecular Basis of Leukemia - Full text - MIT Libraries
DG Gilliland, CT Jordan, CA Felix, CT Jordan - Hematology, 2004 - asheducationbook.org
... 6 Germline NF1 mutations and somatic RAS mutations are known to activate the ... MLL
translocations, it recently was observed that the Hoxa9 and Meis1 genes are ...
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Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in …
N Van Roy, H Van Limbergen, J Vandesompele, M Van … - Genes Chromosomes and Cancer, 2001 - doi.wiley.com
... M. Rocchi, Resources for Molecu- lar Cytogenetics, Institute of Genetics, Bari,
Italy), BAC clones RPCI 11 89G16 (2p16), RPCI 11 444B4 for the MEIS1 gene (2p14 ...
Cited by 14 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Plenary Talk P01: Experience-dependent modification of neural circuits–cellular and molecular … - Full text - MIT Libraries
MM Poo - Journal of Neurochemistry - blackwell-synergy.com
... USA Benign peripheral nerve tumors called neurofibromas are a major source of morbidity
for patients with the inherited disease neurofibro- matosis type 1 (NF1 ...
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Bibliography Current World Literature
J Arcaroli, KY Yang, HK Yum… - Current Opinion in Hematology, 2004 - co-hematology.com
... SHP-2 and myeloid malignancies. Review (pp 44-50). Birnbaum RA, OMarcaigh A, Wardak
Z, et al.: Nf1 and Gmcsf interact in myeloid leukemogenesis. ...
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Expression of genes involved in vascular development and angiogenesis in endothelial cells freshly … - Full text - MIT Libraries
CJ Favre, M Mancuso, K Maas, JW McLean, P Baluk, … - Am. J. Physiol. Heart. Circ. Physiol, 2003 - ajpheart.physiology.org
Page 1. Am. J. Physiol.- Heart & Circ. Physiol. #H-00983-2002.R1 FINAL ACCEPTED
VERSION June 27, 2003 Expression of genes involved in vascular development ...
Cited by 12 - Web Search - intl-ajpheart.physiology.org - ajpheart.physiology.org - ncbi.nlm.nih.gov