Meis homeoproteins directly regulate Pax 6 during vertebrate lens morphogenesis - Full text - MIT Libraries
X Zhang, A Friedman, S Heaney, P Purcell, RL Maas - Genes & Development, 2002 - genesdev.org
... 4) Meis2 interacts genetically with Pax6 and leads to increased Pax6 expression
in developing lens; (5) dominant-negative Meis1 represses Pax6 expression in ...
Cited by 12 - Web Search - genesdev.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Hematopoietic, angiogenic and eye defects in Meis 1 mutant animals - Full text - MIT Libraries
T Hisa, SE Spence, RA Rachel, M Fujita, T Nakamura … - The EMBO Journal, 2004 - embojournal.npgjournals.com
... the development of the microvasculature and the mammalian eye, a role consistent
with a recent report suggesting that MEIS1 regulates Pax6 expression during ...
Cited by 9 - Web Search - nature.com - embojournal.npgjournals.com - ncbi.nlm.nih.gov

A Set of Hox Proteins Interact with the Maf Oncoprotein to Inhibit Its DNA Binding, Transactivation, … - Full text - MIT Libraries
K Kataoka, K Yoshitomo-Nakagawa, S Shioda, M … - J Biol Chem, 2001 - jbc.org
... MBP-Maf and analyzed by SDS-PAGE. B, pull-down assay of 35 S-labeled Pax6
and Meis1 (indicated by asterisks) using MBP or MBP-Maf. ...
Cited by 22 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Heterodimeric Pbx-Prep 1 Homeodomain Protein Binding to the Glucagon Gene Restricting Transcription … - Full text - MIT Libraries
S Herzig, L Fuezesi, W Knepel - J Biol Chem, 2000 - jbc.org
... Antibodies-- Homeodomain protein-specific antibodies against Pax6 ( Pax6) (53),
Meis1 ( Meis1) (54), Cdx-2 ( Cdx-2) (55), and Engrailed-1/2 ( Enhb-1) (56) have ...
Cited by 12 - Web Search - intl.jbc.org - jbc.org - ncbi.nlm.nih.gov

Hox regulation of normal and leukemic hematopoietic stem cells.
C Abramovich, RK Humphries - Current Opinion in Hematology, 2005 - co-hematology.com
... performed in Drosophila [80] and by the reported ability of Meis1 to bind and activate
the promoter of Pax6 and platelet factor 4 gene in mammalian cells [81,82 ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Lens differentiation and crystallin regulation: a chick model
HM REZA, K YASUDA - Int. J. Dev. Biol, 2004 - bsw3.aist-nara.ac.jp
... Transgenic experiments revealed that Meis2, but not Meis1, could upregulate ectodermal
Pax6 expression in mice, whereas loss-of- function experiments using ...
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Pbx genes are required in Xenopus lens development.
R MORGAN, J SOHAL, M PALEJA, R PETTENGELL - Int. J. Dev. Biol, 2004 - ijdb.ehu.es
... (C) The explants were also analysed for Pax6, L-Maf ... binding domains of myogenic bHLH
transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1 ...
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PAX 6 and Congenital Eye Malformations - Full text - MIT Libraries
IM HANSON - Pediatric Research, 2003 - intl.pedresearch.org
... 4) binds the homeoproteins Six3, Meis1, and Meis2, which are expressed in the lens
placode (56, 67, 68). Pax6 expression is up regulated in the lenses of ...
Cited by 3 - Web Search - med.nyu.edu - pedresearch.org - ncbi.nlm.nih.gov - all 5 versions »

Transcriptional profile analysis of in vivo adult subventricular zone (SVZ) neurogenesis
DA Lim, M Suarez-Farinas, F Naef, C Hacker, B Menn … - asterion.rockefeller.edu
... or St. Transcription factors Meis1, Mrg1/Meis2, Pbx1, Pbx3, Pax6, Madh1/Smad1,
Runx2, and Dlx5 were found in this group. These transcription ...
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Retinoic acid signalling specifies intermediate character in the developing telencephalon - Full text - MIT Libraries
M Marklund, M Sjoedal, BC Beehler, TM Jessell, T … - Development, 2004 - dev.biologists.org
... RA acts as an activator of MEIS1 and MEIS2 expression in the proximal region of
the ... 6% in untreated stage 14 I explants, P<0.01), the number of PAX6 + cells (7 ...
Cited by 1 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

The homeodomain Pbx2-Prep1 complex modulates hepatocyte nuclear factor 1 alpha-mediated activation … - Full text - MIT Libraries
PA Gregory, PI Mackenzie - Mol. Pharmacol, 2002 - intl-molpharm.aspetjournals.org
... The Prep1 antibody does not recognize in vitro translated Meis1 on Western blots ...
with the glucagon enhancer element G3 and attenuate Pax6-mediated activation ...
Cited by 4 - Web Search - molpharm.aspetjournals.org - ncbi.nlm.nih.gov

Patterning defects in the primary axonal scaffolds caused by the mutations of the extradenticle and … - Full text - MIT Libraries
T Nagao, K Endo, H Kawauchi, U Walldorf, K … - Development Genes and Evolution, 2000 - springerlink.com
... In ad- dition, expression of a Drosophila Pax6 gene, eyeless, is significantly
suppressed in the mutants except for the most anterior region. ...
Cited by 6 - Web Search - uniklinik-saarland.de - med-rz.uni-sb.de - biol.tsukuba.ac.jp - all 7 versions »

Luciferase Reporters: Less is More
A Paguio, B Almond, F Fan, P Stecha, D Garvin, M … - promega.com
... HNF1 Brn-3 HNF 1 HNF 1 AD-b Nkx2.5 GBF3 GBF3 HIF-1 ATF EKLF Musc. GBF1 PAX6
Tax/CREB MEIS1 X-Box B-cell Elk-1 IRF2 FoxA2 HMX3 LHX3 Neu1/3 Sox-5 HoxC-Rel ...
Web Search

A genomewide survey of developmentally relevant genes in Ciona intestinalis - Full text - MIT Libraries
S Wada, M Tokuoka, E Shoguchi, K Kobayashi, A Di … - Dev Genes Evol, 2003 - springerlink.com
... 93% $ Pax3/7 Pax3/7 genewise.209.17.1 36362 Q96H85 Pax-3 99% $ Pax4/6 Pax6
genewise.337.13.1 32251 P26367 Pax-6 98% $ orphan Pax3 ...
Cited by 22 - Web Search - ncbi.nlm.nih.gov

Meis family proteins are required for hindbrain development in the zebrafish - Full text - MIT Libraries
SK Choe, N Vlachakis, CG Sagerstrom - Development, 2002 - dev.biologists.org
... 4Q). Expression of pax6 reveals six boundaries in control embryos (Fig. ... Meis1 and
pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface ...
Cited by 12 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The last common bilaterian ancestor - Full text - MIT Libraries
DH Erwin, EH Davidson - Development, 2002 - dev.biologists.org
... the terminus of the developmental process, just as is the case of pax6. ... and of other
homologous transcription factors to specify proximal regions (meis1/2 and ...
Cited by 37 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

pGL3 Luciferase Reporter Vectors
I Description, IIIP Components, IVC Methods, I … - promega.com
... HNF1 Brn-3 HNF 1 HNF 1 AD-b Nkx2.5 GBF3 GBF3 HIF-1 ATF EKLF Musc. GBF1 PAX6
Tax/CREB MEIS1 X-Box B-cell Elk-1 IRF2 FoxA2 HMX3 LHX3 Neu1/3 Sox-5 HoxC-Rel ...
Web Search - genomics.sbg.ac.at - sci.sdsu.edu - shpromega.cn - all 8 versions »

Expression profiling of lineage differentiation in pluripotential human embryonal carcinoma cells - Full text - MIT Libraries
J Houldsworth, SC Heath, GJ Bosl, L Studer, RS … - Cell Growth Differ, 2002 - cgd.aacrjournals.org
... program (CCND1 and MYCN), or up-regulated (CDKN1A, NEFL, PAX6, and ANXA1 ... transcript
levels of other homeobox-containing genes were identified [MEIS1, MRG1, and ...
Cited by 6 - Web Search - cgd.aacrjournals.org - ncbi.nlm.nih.gov

The role of homeobox genes in hematopoiesis
MC Magli - Biotherapy, 1998 - ingentaconnect.com
... is supported by the finding that the human homologues of Meis1, Meis2 and ... and Aniridia
can be correlated with molecular alterations of PAX2, PAX3 and PAX6. ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Loss of Gli3 and Shh function disrupts olfactory axon trajectories. - Full text - MIT Libraries
CW BALMER, AS La MANTIA - THE JOURNAL OF COMPARATIVE NEUROLOGY, 2004 - doi.wiley.com
... Saco, ME; Gong and Shipley, 1996; Morse et al., 1998), MASH1 (rabbit; generously
provided by J. Johnson; Horton et al., 1999), MEIS1 (rabbit; generously ...
Web Search - ncbi.nlm.nih.gov

Prep 1. 1 has essential genetic functions in hindbrain development and cranial neural crest cell … - Full text - MIT Libraries
G Deflorian, N Tiso, E Ferretti, D Meyer, F Blasi, … - Development, 2004 - dev.biologists.org
... 1 (RZPD clone MPMGp609C2025Q8), krox20 (Oxtoby and Jowett, 1993), pax6.1 (Puschel ...
Dendrogram, obtained using the ClustalW program, of zebrafish Meis1.1, Meis2.1 ...
Cited by 1 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Ethidium Bromide Provides a Simple Tool for Identifying Genuine DNA-Independent Associations - Full text - MIT Libraries
J Lai, W Herr - Proceedings of the National Academy of Sciences - pnas.org
... Lawrence, and C. Largman HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid ...
Kamachi, M. Uchikawa, A. Tanouchi, R. Sekido, and H. Kondoh Pax6 and SOX2 ...
Web Search - adsabs.harvard.edu

Activation of Stem-Cell Specific Genes by HOXA9 and HOXA10 Homeodomain Proteins in CD34 Human Cord …
CM Ferrell, ST Dorsam, H Ohta, RK Humphries, MK … - stemcells.alphamedpress.org
... potentials of multiple NUP98-Hox fusion proteins alone or with Meis1. ... Identification
of differentially expressed genes in mouse Pax6 heterozygous lenses. ...
Web Search - dx.doi.org - stemcells.alphamedpress.org

Gene expression analysis in mice with elevated glial fibrillary acidic protein and Rosenthal fibers … - Full text - MIT Libraries
TL Hagemann, SA Gaeta, MA Smith, DA Johnson, JA … - Human Molecular Genetics, 2005 - hmg.oxfordjournals.org
... The transcription factor Pax6, which is expressed in periglomerular cells (31 ... Pbx1,
Pbx3 and Meis1, co-factors for homeodomain transcription factors, also ...
Web Search - hmg.oxfordjournals.org

Full Article - Full text - MIT Libraries
FR Goodman, PJ Scambler - Clinical Genetics, 2001 - blackwell-synergy.com
... Similar mutations in other homeodomain proteins, such as PAX6 [28], EMX2 [29 ... implicated
in leukaemogenesis [59,60], and co-activation of MEIS1 and HOXA9 may be ...
Web Search - blackwell-synergy.com

Xpbx 1 b and Xmeis 1 b play a collaborative role in hindbrain and neural crest gene expression in … - Full text - MIT Libraries
R Maeda, A Ishimura, K Mood, EK Park, AM Buchberg, … - Proceedings of the National Academy of Sciences, 2002 - pnas.org
... Anti-Meis1 antibody or anti-Pbx1b antibody was used to detect the indicated ... P. Purcell,
and RL Maas Meis homeoproteins directly regulate Pax6 during vertebrate ...
Cited by 9 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Structure and Regulation of the mDot1 Gene, a Murine Histone H3 Methyltransferase
W Zhang, Y Hayashizaki, BC Kone, BC Kone, F FCP - biochemj.org
Page 1. BJ2003/0839.R1. 1 Structure and Regulation of the mDot1 Gene, a Murine
Histone H3 Methyltransferase Wenzheng Zhang 1 , Yoshihide ...
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Human HOX gene mutations - Full text - MIT Libraries
FR Goodman, PJ Scambler - Clinical Genetics, 2001 - ingentaconnect.com
... Similar mutations in other homeodomain proteins, such as PAX6 (28), EMX2 (29), PITX2
(formerly RIEG) (30) and HLXB9 (31, 32), appear to act as null alleles ...
Cited by 31 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Combinatorial control of Drosophila eye development by Eyeless, Homothorax, and Teashirt - Full text - MIT Libraries
J Bessa, B Gebelein, F Pichaud, F Casares, RS Mann - Genes & Development, 2002 - genesdev.org
... 2001 ). Toy, a second Pax6 family member in flies (Czerny et al. 1999 ), may also
be part of the combinatorial control of eye development described here. ...
Cited by 17 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Identification of Cis-Element Regulating Expression of the Mouse Fgf10 Gene during Inner Ear …
H Ohuchi, A Yasue, K Ono, S Sasaoka, S Tomonari, A … - Key words, 2005 - doi.wiley.com
Page 1. PATTERNS & PHENOTYPES Identification of Cis-Element Regulating Expression
of the Mouse Fgf10 Gene during Inner Ear Development ...
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TERATOLOGY SOCIETY
P SESSIONS - doi.wiley.com
... At least 9 proteins associated with this pathway were detected, including Pax6,
Cdc25c, Mphosph 10, Chimaerin, Gem, Rtkn, Tnfr, Nemo and 14-3-3. The classical ...
Web Search - doi.wiley.com

ES cell neural differentiation reveals a substantial number of novel ESTs
G Bain, FC Mansergh, MA Wride, JE Hance, A Isogawa … - Functional & Integrative Genomics, 2000 - springerlink.com
Page 1. Abstract We have used a method for synchronously dif- ferentiating murine
embryonic stem (ES) cells into func- tional neurons and glia in culture. ...
Cited by 4 - Web Search - 136.159.173.207 - camit.org - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Homeodomain revisited: a lesson from disease-causing mutations - Full text - MIT Libraries
YI Chi - Human Genetics, 2005 - springerlink.com
... R271H PS/DB PS/DB PS PS/DB DB DB Coloboma of optic nerve PAX6 607108
Pairedbox-homeodomain (210–269) F258S PS Neuroblastoma PHOX2B ...
Web Search - ncbi.nlm.nih.gov

Identification of a Hoxd10-regulated transcriptional network and combinatorial interactions with … - Full text - MIT Libraries
E Hedlund, SL Karsten, L Kudo, DH Geschwind, EM … - Journal of Neuroscience Research, 2004 - doi.wiley.com
Page 1. Identification of a Hoxd10-Regulated Transcriptional Network and
Combinatorial Interactions With Hoxa10 During Spinal Cord Development ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The role of Wingless signaling in establishing the anteroposterior and dorsoventral axes of the eye … - Full text - MIT Libraries
JD Lee, JE Treisman - Development, 2001 - dev.biologists.org
... To determine whether axin mutant cells showed other indications of anterior identity,
we stained axin clones for the Pax6 protein Eyeless (Ey), which is ...
Cited by 18 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Hox Genes and Their Candidate Downstream Targets in the Developing Central Nervous System
ZN Akin, AJ Nazarali - springerlink.com
... The PBC proteins together with the MEIS protein family (myeloid ecotropic insertion
site genes: MEIS1, MEIS2, MEIS3; and Pbx regulating protein genes: PREP1 ...
Web Search

Hearing in Drosophila: development of Johnston's organ and emerging parallels to vertebrate ear … - Full text - MIT Libraries
G Boekhoff-Falk - Dev. Dyn, 2005 - doi.wiley.com
... In the case of eye development, selectors such as eye- less/Pax6, sine oculis, eyes
absent, and dachshund are conserved from Dro- sophila to vertebrates as are ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase - Full text - MIT Libraries
W ZHANG, Y HAYASHIZAKI, C Bruce - Biochem. J, 2004 - biochemj.org
Page 1. Biochem. J. (2004) 377, 641–651 (Printed in Great Britain) 641 Structure
and regulation of the mDot1 gene, a mouse histone H3 methyltransferase ...
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cis-Regulatory Control of Cell Fate-Specific Genes in Caenorhabditis elegans Vulval Organogenesis
M Kirouac, PW Sternberg - etd.caltech.edu
Page 1. cis-Regulatory Control of Cell Fate-Specific Genes in Caenorhabditis elegans
Vulval Organogenesis Martha Kirouac and Paul W. Sternberg ...
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Retinoid-Induced Limb Malformations
GS Lee, DM Kochhar, MD Collins - Current Pharmaceutical Design, 2004 - ingentaconnect.com
Page 1. Current Pharmaceutical Design, 2004, 10, 2657-2699 2657 1381-6128/04
$45.00+.00 © 2004 Bentham Science Publishers Ltd. Retinoid ...
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cis-Regulatory control of three cell fate-specific genes in vulval organogenesis of C. elegans and C … - Full text - MIT Libraries
M Kirouac, PW Sternberg - Dev Biol, 2003 - etd.caltech.edu
Page 1. cis-Regulatory Control of Three Cell Fate-Specific Genes in Vulval
Organogenesis of C. elegans and C. briggsae Thesis by Martha Kirouac ...
Cited by 16 - View as HTML - Web Search - etd.caltech.edu - ncbi.nlm.nih.gov