Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice - Full text - MIT Libraries
JJ Moskow, F Bullrich, K Huebner, IO Daar, AM … - Mol. Cell. Biol, 1995 - mcb.asm.org
... 10 0270-7306/95/$04.00 0 Copyright 1995, American Society for Microbiology Meis1,
a PBX1-Related Homeobox Gene Involved in Myeloid Leukemia in BXH-2 Mice ...
Cited by 96 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine …
N Pineault, CD Helgason, HJ Lawrence, RK Humphries - Exp. Hematol, 2002 - ingentaconnect.com
... Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells
throughout murine hematopoietic ontogeny. Authors: Pineault ...
Cited by 31 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in … - Full text - MIT Libraries
PS Knoepfler, KR Calvo, H Chen, SE Antonarakis, MP … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
... 14553-14558, December 1997. Genetics. Meis1 and pKnox1 bind DNA cooperatively with
Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1. ...
Cited by 64 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins - Full text - MIT Libraries
WF Shen, JC Montgomery, S Rozenfeld, JJ Moskow, HJ … - Mol Cell Biol, 1997 - mcb.asm.org
... The homeodomain of Meis1 has homology with that of Pbx1, and both proteins contain
a 3-amino-acid insertion which is a feature of the TALE class of homeobox ...
Cited by 86 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

[CITATION] Meis1, a PBX1-related homeobox gene involved in BXH-2 murine myeloid leukemia - Full text - MIT Libraries
JJ Moscow, F Bullrich, K Huebner, IO Daar, AM … - Mol. Cell. Biol, 1995
Cited by 3 - Web Search

The subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals … - Full text - MIT Libraries
J Berthelsen, C Kilstrup-Nielsen, F Blasi, F … - Genes Dev, 1999 - genesdev.org
... Moskow, J., F. Bullrich, K. Huebner, I. Daar, and A. Buchberg. 1995. Meis1, a
PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol. Cell. ...
Cited by 78 - Web Search - genesdev.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Hoxa 9 transforms primary bone marrow cells through specific collaboration with Meis 1 a but not Pbx … - Full text - MIT Libraries
E Kroon, J Krosl, U Thorsteinsdottir, S Baban, AM … - The EMBO Journal, 1998 - embojournal.npgjournals.com
... Hoxa9, Meis1 and Pbx1 encode homeodomaincontaining proteins implicated
in leukemic transformation in both mice and humans. Hoxa9 ...
Cited by 114 - Web Search - emboj.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Conserved regulation of proximodistal limb axis development by Meis1/Hth - Full text - MIT Libraries
N Mercader, E Leonardo, N Azpiazu, A Serrano, G … - Nature, 1999 - nature.com
... 9. Moskow,JJ, Bullrich,F., Huebner,K., Daar,IO & Buchberg,AM Meis1, a PBX1-related
homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol. Cell. Biol. ...
Cited by 52 - Web Search - nature.com - adsabs.harvard.edu - ncbi.nlm.nih.gov - all 5 versions »

Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins - Full text - MIT Libraries
CP Chang, Y Jacobs, T Nakamura, NA Jenkins, NG … - Mol. Cell. Biol, 1997 - mcb.asm.org
... Meis1 and Pbx1 dimerize on the composite DNA sequence TGATTGACAG containing 5 Pbx
and 3 Meis half sites. ... c Consensus for sites bound by Pbx1-Meis1 complexes. ...
Cited by 85 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

[CITATION] Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice - Full text - MIT Libraries
JJ Moscow, F Bullrich, K Huebner, IO Daar, AM … - Mol. Cell. Biol, 1995
Cited by 2 - Web Search

Cooperative activation of Hoxa and Pbx 1-related genes in murine myeloid leukaemias
T Nakamura, DA Largaespada, JD Shaughnessy, NA … - Nature Genetics, 1996 - ncbi.nlm.nih.gov
... we identify three genes whose expression is activated by proviral integration in
BXH-2 leukaemias; Hoxa7, Hoxa9, and a Pbx1-related homeobox gene, Meis1. ...
Cited by 117 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells - Full text - MIT Libraries
WF Shen, S Rozenfeld, A Kwong, LG Koemueves, HJ … - Mol Cell Biol, 1999 - mcb.asm.org
... Each of the epitope-tagged MEIS1, PBX1, and HOXA9 proteins was shown to be functional
in DNA site selection or EMSA analyses (see Results) and in previous ...
Cited by 19 - Web Search - mcb.asm.org - pubmedcentral.nih.gov

Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias
HJ Lawrence, S Rozenfeld, C Cruz, K Matsukuma, A … - Leukemia, 1999 - nature.com
... Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid
leukemias ... 1 MEIS1 expression in leukemic cell lines ...
Cited by 47 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Prep 1, a novel functional partner of Pbx proteins - Full text - MIT Libraries
J Berthelsen, V Zappavigna, F Mavilio, F Blasi - The EMBO Journal, 1998 - embojournal.npgjournals.com
... Meis1-Pbx DNA-binding activities are present in extracts from several cell lines,
and can be reconstituted with in vitro translated Meis1 and Pbx1 (Chang et al ...
Cited by 66 - Web Search - emboj.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov - all 6 versions »

The Hexapeptide LFPWMR in Hoxb-8 is Required for Cooperative DNA Binding with Pbx1 and Pbx2 Proteins - Full text - MIT Libraries
STC Neuteboom, LTC Peltenburg, MA van Dijk, C … - Proceedings of the National Academy of Sciences - pnas.org
... Antonarakis, and MP Kamps Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing
an interaction surface disrupted in oncoprotein E2a-Pbx1 PNAS, December 23 ...
Cited by 51 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia - Full text - MIT Libraries
U Thorsteinsdottir, E Kroon, L Jerome, F Blasi, G … - Mol Cell Biol, 2001 - dx.doi.org
... In this report, we demonstrate that HOXB3, which is highly divergent from HOXA9,
also genetically interacts with MEIS1, but not with PBX1, in generating AML. ...
Cited by 44 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Dorsotonals/homothorax, the Drosophila homologue of meis1, interacts with extradenticle in … - Full text - MIT Libraries
E Kurant, CY Pai, R Sharf, N Halachmi, YH Sun, A … - Development, 1998 - dev.biologists.org
... the hth gene. hth encodes a homeodomain-containing protein that is most
similar to the murine proto-oncogene meis1. The hth gene ...
Cited by 65 - Web Search - dev.biologists.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov

A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors … - Full text - MIT Libraries
P Knoepfler, DA Bergstrom, T Uetsuki, I Dac- … - Nucleic Acids Research, 1999 - nar.oupjournals.org
... and partially disrupted the tetrameric complex; (iii) that inclusion of a C-terminal
deletion of Meis1 increases the mobility of both Meis1-Pbx1 and of the ...
Cited by 16 - Web Search - nar.oxfordjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Meis1-mediated apoptosis is caspase-dependent and can be suppressed by coexpression of HoxA9 in … - Full text - MIT Libraries
PJ Wermuth, AM Buchberg - Blood, 2005 - bloodjournal.org
... Results demonstrated that the ability of Meis1 and Pbx1 to induce apoptosis is not
restricted to lymphoid cells but includes myeloid and nonhematopoietic cells ...
Cited by 3 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Identification of Homeodomain Proteins, PBX1 and PREP1, Involved in the Transcription of Murine … - Full text - MIT Libraries
SH Chao, JR Walker, SK Chanda, NS Gray, JS … - Mol Cell Biol, 2003 - mcb.asm.org
... nonleukemogenic retrovirus. It has been shown previously that PBX1-MEIS1
or PBX1-PREP1 heterodimers bind the PCE (5, 24). To test ...
Cited by 2 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

Induction of acute myeloid leukemia (AML) in mice by the human leukemia-specific fusion gene NUP98- … - Full text - MIT Libraries
N Pineault, C Buske, M Feuring-Buske, C Abramovich … - Mol. Cell. Biol, 2004 - bloodjournal.org
... specific fusion gene NUP98-HOXD13 in concert with Meis1 ... Running Title: Induction
of AML by NUP98-HOXD13 and Meis1 Word Count: 5769 Abstract Count: 195 ...
Cited by 14 - Web Search - dx.doi.org - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

HOXA10, Pbx2, and Meis1 protein expression in the human endometrium: formation of multimeric … - Full text - MIT Libraries
JL Sarno, HJ Kliman, HS Taylor, HS Taylor, A … - J Clin Endocrinol Metab, 2005 - jcem.endojournals.org
... Using immunohistochemical analysis, we found that Pbx2 and Meis1, but not
Pbx1, Pbx3, or Meis2, were expressed in human endometrium. ...
Cited by 2 - Web Search - jcem.endojournals.org - ncbi.nlm.nih.gov

Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex - Full text - MIT Libraries
HD Ryoo, T Marty, F Casares, M Affolter, RS Mann - Development, 1999 - dev.biologists.org
... Further, these results are consistent with the interaction domains defined in the
vertebrate proteins, MEIS1 and PBX1 (Chang et al., 1997; Knoepfler et al ...
Cited by 56 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and … - Full text - MIT Libraries
L Selleri, MJ Depew, Y Jacobs, SK Chanda, KY Tsang … - Development, 2001 - dev.biologists.org
... The subcellular localization of PBX1 and EXD proteins depends on nuclear import ... Members
of the meis1 and pbx homeodomain protein families cooperatively bind a ...
Cited by 27 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Meis and Hox: a mighty pair defeats apoptosis - Full text - MIT Libraries
T Nakamura - Blood, 2005 - bloodjournal.org
... Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells
throughout murine hematopoietic ontogeny. Exp Hematol. ...
Web Search

Rapid Generation of de novo Biological Pathways from Large-Scale Gene Expression Data Using the …
DC Siu - ingenuity.com
... Application RBBP7 MST4 SH3BP2 FLI1 SYK HDAC6 (In Network 1.Data not shown)
MBP MEIS1 HOXA9 PBX1 PBX2 LGALS1 CD44 CD4 regulates MBP ...
View as HTML - Web Search

Meis1 (C-17): sc-10599
S CRUZ - cosmobio.co.jp
... Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface
disrupted in oncoprotein E2a-Pbx1. Proc. Natl. Acad. Sci. ...
View as HTML - Web Search

MEIS C Termini Harbor Transcriptional Activation Domains That Respond to Cell Signaling - Full text - MIT Libraries
H Huang, M Rastegar, C Bodner, SL Goh, I Rambaldi, … - J Biol Chem, 2005 - jbc.org
... We correlate transcriptional activation of Hoxb1 with histone acetylation and MEIS1,
PBX1, and HOX recruitment to the ARE and map TSA- and PKA-responsive ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias
N Genetics - Nature Genetics, 1996 - nature.com
... ISI | ChemPort |; Moscow, JJ, Bullrich, F., Huebner, K., Daar, IO & Buchberg, AM
Meis1, a PBX1-related homeobox gene involved in BXH-2 murine myeloid leukemia. ...
Web Search - nature.com - Get it from MIT Libraries

20, 847–854 (1998). - Full text - MIT Libraries
N Methods, J Microsc - Proc. Natl Acad. Sci. USA, 1994 - nature.com
... Meis1 regulates Pbx1 activity by promoting nuclear import of the Pbx1 protein; and
that ectopic expression of Meis1 in chicken and hth in Drosophila disrupts ...
Web Search

Differences in Gene Expression between Wild Type and Hoxa 1 Knockout Embryonic Stem Cells after … - Full text - MIT Libraries
E Martinez-Ceballos, P Chambon, LJ Gudas - Journal of Biological Chemistry - jbc.org
... and Hox Gene Transcription in the ES Cell Lines: Pbx1 and Meis1—Hox proteins exert
their activity by forming protein complexes with Meis1 or Pbx1 that bind ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization - Full text - MIT Libraries
BB Zeisig, T Milne, MP Garcia-Cuellar, S Schreiner … - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... Moskow, JJ, F. Bullrich, K. Huebner, IO Daar, and AM Buchberg. 1995. Meis1, a
PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol. Cell. ...
Cited by 12 - Web Search - dx.doi.org - mcb.asm.org - ncbi.nlm.nih.gov - all 6 versions »

Pbx1 is Converted into a Transcriptional Activator Upon Acquiring the N-Terminal Region of E2A in … - Full text - MIT Libraries
MAV Dijk, PM Voorhoeve, C Murre - Proceedings of the National Academy of Sciences - pnas.org
... Antonarakis, and MP Kamps Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing
an interaction surface disrupted in oncoprotein E2a-Pbx1 PNAS, December 23 ...
Cited by 1 - Web Search - pubmedcentral.nih.gov

Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with … - Full text - MIT Libraries
N Pineault, C Abramovich, H Ohta, RK Humphries - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... are the key to leukemic transformation, several of the fusions tested (NB3, NB4,
ND13, ND13hd, and NA10hd) lacked both known Pbx1- and Meis1-interacting motifs ...
Cited by 11 - Web Search - dx.doi.org - mcb.asm.org - ncbi.nlm.nih.gov - all 6 versions »

Members of the Meis 1 and Pbx Homeodomain Protein Families Cooperatively Bind a cAMP-responsive … - Full text - MIT Libraries
LJ Bischof, N Kagawa, JJ Moskow, Y Takahashi, A … - J Biol Chem, 1998 - jbc.org
... This further supports Meis1 as a Pbx1 binding partner on CRS1 within nuclear extract
and also indicates a putative Meis1 binding site adjacent to the Pbx site. ...
Cited by 31 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause … - Full text - MIT Libraries
DB Sykes, MP Kamps - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... on target genes and that E2a/Pbx1 heterodimerizes with Hox proteins on target genes
presents the possibility that both E2a/Pbx1 and Meis1 could function by ...
Cited by 4 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Phylogenetic classification and molecular evolution of knotted1 homeobox genes - Full text - MIT Libraries
ADDWRGP Mulay, VSGPK Ranjekar - Theor Appl Genet, 1999 - springerlink.com
... present study shows PKNOX1 to be closer to MEIS1 than to KN1, which is well supported
by the common DNA-binding sites of PKNOX1 and MEIS1 with PBX1 (Knoep#er ...
Web Search

Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires … - Full text - MIT Libraries
GG Wang, MP Pasillas, MP Kamps - Blood, 2005 - bloodjournal.org
... Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells
throughout murine hematopoietic ontogeny. Exp Hematol. ...
Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov

Transplantable cell lines generated with NUP98–Hox fusion genes undergo leukemic progression by …
V Columbia, C BC - Leukemia, 2005 - nature.com
... online 3 March 2005 Keywords: complementation; transplantable; Meis1; NUP98-Hox ...
expression and by translocations involving their cofactor Pbx1 and upstream ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Fusion Genes Transplantable cell lines generated with NUP98− Hox fusion genes undergo leukemic …
N Pineault, C Abramovich, RK Humphries - Leukemia, 2005 - nature.com
... Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout
murine hematopoietic ontogeny. Exp Hematol 2002; 30: 49−57. ...
Web Search

Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells - Full text - MIT Libraries
C Buske, M Feuring-Buske, C Abramovich, K … - Blood, 2002 - bloodjournal.org
... that lead to the differential gene effect are not known, but data point to a pivotal
role of the TALE homeobox genes and Hox cofactors Meis1 and Pbx1 for the ...
Cited by 23 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

The novel homeoprotein Prep 1 modulates Pbx-Hox protein cooperativity - Full text - MIT Libraries
J Berthelsen, V Zappavigna, E Ferretti, F Mavilio, … - The EMBO Journal, 1998 - embojournal.npgjournals.com
... Similarly, the Meis1-Pbx1 complex binds preferentially to a combined Pbx-Meis binding
site TGAT-TGACAG, in which the Meis halfsite is identical to the TGACAG ...
Cited by 77 - Web Search - emboj.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov - all 7 versions »

The Role of NUP98 Gene Fusions in Hematologic Malignancy
C SLAPE, PD APLAN - therapy - dx.doi.org
... Some orphan homeobox genes, such as MEIS1 and PBX1, encode transcriptional
co-activators which interact with the HOX proteins and are required for these ...
Cited by 4 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The tandem complex of BEL and KNOX partners is required for transcriptional repression of ga 20 ox 1 - Full text - MIT Libraries
H Chen, AK Banerjee, DJ Hannapel - The Plant Journal, 2004 - blackwell-synergy.com
... Two interacting TALE proteins of vertebrates, Meis1 and Pbx1, dimerize and bind
to the composite DNA sequence, TGATTGACAG, containing 5'-Pbx and 3'-Meis half ...
Cited by 6 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity - Full text - MIT Libraries
Y Jacobs, CA Schnabel, ML Cleary - Mol. Cell. Biol, 1999 - mcb.asm.org
... Moskow, JJ, F. Bullrich, K. Huebner, IO Daar, and AM Buchberg. 1995. Meis1, a
PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol. Cell. ...
Cited by 74 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

HOMEOBOX GENE NETWORKS AND THE REGULATION OF HEMATOPOIESIS
GUY SAUVAGEAU, RK HUMPHRIES, HJ LAWRENCE, C … - doi.wiley.com
... This indicates a potential combinatorial code for Hox gene action, and, as shown
in Figure 9.1, suggests that Meis1 and Pbx1 may induce transformation when ...
Web Search

Application of Ingenuity Pathways Analysis to Identify Putative Biomarkers of Childhood Leukemia …
IA Spectrum - Cancer - ingenuity.com
... CD19,CD2, CD28 CHD4,Histone H3,Histone H4, MADH1, MADH4,MEIS1, MLL,PBX1,
SIN3A, SMARCA2, SPP1,TAF6,TBP CDKN1A,E2F1, HOXA10, HOXA11 ...
View as HTML - Web Search

Estrogen-dependent E2a/Pbx1 myeloid cell lines exhibit conditional differentiation that can be … - Full text - MIT Libraries
DB Sykes, MP Kamps - Blood, 2001 - bloodjournal.org
... E2a/Pbx1 arrests myeloid differentiation in a DNA binding-dependent manner, possibly ...
Furthermore, expression of Meis1, Meis2, and Meis3 was not detected in the ...
Cited by 10 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov - all 5 versions »

Myeloid Leukemia: Disease Genes and Mouse Models
BXH Mice - content.karger.com
... 16 Moskow JJ, Bullrich F, Huebner K, Daar IO, Buchberg AM: Meis1, a PBX1-related
homeobox gene involved in myeloid leukemia in BXH-2 mice. ...
Web Search - content.karger.com

Functional and Cooperative Interactions between the Homeodomain PDX 1, Pbx, and Prep 1 Factors on … - Full text - MIT Libraries
G Goudet, S Delhalle, F Biemar, JA Martial, B … - J Biol Chem, 1999 - jbc.org
... 6 shows that a very strong cooperative binding occurs using Pbx1a and Prep-1 (lane
6), whereas formation of a Pbx1-Meis1 complex was also detectable, but much ...
Cited by 33 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov