Cooperative signaling between cytokine receptors and the glucocorticoid receptor in the expansion of … - Full text - MIT Libraries
A Kolbus, M Blazquez-Domingo, S Carotta, W Bakker, … - Blood, 2003 - bloodjournal.org
... activated (Figure 1B). In contrast, the ratio between c-MYB and GATA1 remains
constant in the presence of Epo, SCF, and Dex. Steady-state ...
Cited by 15 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov - all 7 versions »

Increased expression of the distal, but not of the proximal, Gata 1 transcripts during … - Full text - MIT Libraries
AM Vannucchi, S Linari, CS Lin, MJ Koury, MC … - Journal of Cellular Physiology, 1999 - doi.wiley.com
... as Eklf, Scl, and Nfe2, and precedes by 24 h the repression of the expression of
Gata2 and Myb, indicating that the levels of the distal Gata1 transcripts are ...
Cited by 9 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Abnormal WT 1 expression in the CD 34-negative compartment in myelodysplastic bone marrow - Full text - MIT Libraries
JP van Dijk, GHJN Knops, LTF van de Locht, AL … - British Journal of Haematology, 2002 - dx.doi.org
... A haematopoietic specific enhancer has been identified in the WT1 gene that can
be activated by interactions with c-myb or GATA1 (Zhang et al, 1997). ...
Cited by 3 - Web Search - blackwell-synergy.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

… and erythromyeloid differentiation in embryonal stem cells constitutively expressing c-myb - Full text - MIT Libraries
P Melotti, B Calabretta - Blood, 1996 - bloodjournal.org
... Undifferentiated ES cells transfected with intact c-myb, but not cells transfected
with mutant c-myb, expressed CD34, c-kit, GATA1, and flt3 mRNA as well as ...
Cited by 12 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

WT1 and GATA1 expression in myelodysplastic syndrome and acute leukemia
P Patmasiriwat, G Fraizer, H Kantarjian, GF … - Leukemia, 1999 - nature.com
... WT1 and GATA1 expression in myelodysplastic syndrome and acute leukemia P
Patmasiriwat 1,2 , G Fraizer 1,3 , H Kantarjian 4 and GF Saunders 1 ...
Cited by 18 - Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Increased Affinity of c-Myb for CREB-binding Protein(CBP) after CBP-induced Acetylation - Full text - MIT Libraries
Y Sano, S Ishii - J Biol Chem, 2001 - jbc.org
... to the activation domain of c-Myb and mediates c-Myb-dependent transcriptional ... not
only histones but also certain transcriptional factors such as GATA1 and p53 ...
Cited by 18 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb - Full text - MIT Libraries
N Emambokus, A Vegiopoulos, B Harman, E Jenkinson, … - The EMBO Journal, 2003 - embojournal.npgjournals.com
... We are grateful to Stuart Orkin and Susan Dymecki for providing us with the
GATA1-Cre and ... Allen,RD, Bender,TP and Siu,G. (1999) c-Myb is essential for early ...
Cited by 14 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 6 versions »

The making of an erythroid cell
AR Migliaccio, G Migliaccio - Biotherapy, 1998 - ingentaconnect.com
... On the other hand, phenotypes with impaired definitive eythropoiesis have been obtained
knocking-out the expression of Myb, Gata1, Gata2 and Nfe2. ...
Cited by 2 - Web Search

GATA1 Function, a Paradigm for Transcription Factors in Hematopoiesis - Full text - MIT Libraries
R Ferreira, K Ohneda, M Yamamoto, S Philipsen - Mol Cell Biol, 2005 - mcb.asm.org
... The first evidence of the role of GATA1 in eosinophil development came from the
observation that forced GATA1 expression in Myb-Ets-transformed chicken ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Developmental stage− selective effect of somatically mutated leukemogenic transcription factor … - Full text - MIT Libraries
Z Li, FJ Godinho, JH Klusmann, M Garriga-Canut, C … - Nature Genetics, 2005 - nature.com
... Among the genes that are not properly downregulated in Gata1 N megakaryocytes (Fig.
3n), five transcription factors (Myc, Myb, GATA2, PU.1 and ZNFN1A1 (also ...
Cited by 2 - Web Search - nature.com - ncbi.nlm.nih.gov

EKLF and the development of the erythroid lineage
JJ Bieker - Transcription Factors: Normal and Malignant Development of …, 2000 - doi.wiley.com
... Most of these were related to Friend virus genes, metabolic clones (eg, car- bonic
anhydrase), and transcription factors (eg, c-Myb and GATA1), but some clones ...
Cited by 2 - Web Search

Catastrophic for contaminated chickens, murder on mutant mice: harmful to human hematopoiesis? - Full text - MIT Libraries
DP Steensma - Blood, 2005 - bloodjournal.org
... These c-Myb mutant mice are barely out of the wee pup stage, and ... is appropriate:
other putative MMM-modeling mice that either underexpress GATA1 (eg, GATA1 low ...
Web Search

Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion.
SM Onnebo, MM Condron, DO McPhee, GJ Lieschke, AC … - Experimental Hematology, 2005 - eanimal.snu.ac.kr
... In addition, zebrafish homologs of key genes expressed in mammalian erythroid cells
(for example, c-myb and gata1), myeloid cells (for example, spi1 and l ...
View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Neuromedin U: a Myb-regulated autocrine growth factor for human myeloid leukemias - Full text - MIT Libraries
SE Shetzline, R Rallapalli, KJ Dowd, S Zou, Y … - Blood, 2004 - bloodjournal.org
... Of genes known to be induced by Myb, many regulate cell proliferation, differentiation,
and survival including c-myc, 8-12 cdc2, 13 c-kit, 14-16 GATA1, 17 mim1 ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP - Full text - MIT Libraries
J Vervoorts, JM Luescher-Firzlaff, S Rottmann, R … - EMBO Reports, 2003 - emboreports.npgjournals.com
... relevance of c-MYC acetylation, we tested whether DNA binding is affected, as
acetylation of several transcription factors, including c-MYB, GATA1 and E2F, has ...
Cited by 14 - Web Search - nature.com - qb.fcen.uba.ar - ncbi.nlm.nih.gov - all 6 versions »

Zebrafish: a genetic approach in studying hematopoiesis
BH Paw, LI Zon - Curr. Opin. Hematol, 2000 - co-hematology.com
... Expression of GATA1 and c -myb is greatly reduced in the ICM as well as in the dorsal
aorta with normal expression of LMO2 and GATA2 in the posterior portion ...
Cited by 16 - Web Search - co-hematology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Developmental biology of zebrafish myeloid cells
MO Crowhurst, JE Layton, GJ Lieschke - Int. J. Dev. Biol, 2002 - ijdb.ehu.es
... At 18 hpf, zebrafish myb expression in the ICM resembles the pattern of gata1, with
later expression observed in two dispersed populations of cells: one flat ...
Cited by 4 - View as HTML - Web Search - ncbi.nlm.nih.gov - ijdb.ehu.es - Get it from MIT Libraries

Characterization of whole genome radiation hybrid mapping resources for non-mammalian vertebrates - Full text - MIT Libraries
C Kwok, RM Korn, ME Davis, DW Burt, R Critcher, L … - Nucleic Acids Research, 1998 - nar.oupjournals.org
... Zebrafish cDNAs for Tie1, GATA1, GATA2, TTG2, PU.1, c-myb, embryonic [alpha]-globin
(hbe1 on LG3), [alpha]x-globin (hbx on LG12) and retinoic acid receptor 2 ...
Cited by 62 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION - Full text - MIT Libraries
CT Kuo, JM Leiden - Annual Review of Immunology, 1999 - immunol.annualreviews.org
... These factors include GATA2, c-myb, Tal-1/Scl, AML1, and PU.1. The ... The GATA family
of vertebrate transcription factors contains six members, GATA1-GATA6, each ...
Cited by 125 - Web Search - immunol.annualreviews.org - ncbi.nlm.nih.gov

The Zebrafish moonshine Gene Encodes Transcriptional Intermediary Factor 1γ, an Essential Regulator … - Full text - MIT Libraries
DG Ransom, N Bahary, K Niss, D Traver, C Burns, NS … - PLoS Biol, 2004 - dx.doi.org
... arrow). Whole-mount in situ hybridization at 22 hpf including scl, gata2,
gata1, ikaros, and myb in mon tg234 mutants. Expression ...
Cited by 2 - Web Search - medicine.plosjournals.org - plbi.allenpress.com - pubmedcentral.nih.gov - all 8 versions »

Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... COUP HNF4 1698.5 NFY PBX1 170.4 NFKAPPAB50 SP1 57.6 CEBP GATA1 28.9 AHRARNT
MYCMAX 1424.3 HSF2 NFAT 170.3 BRN2 HNF1 56.6 ISRE MYB 28.7 ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

Supplementary Material
C Thisse, LI Zon - sciencemag.org
... Gata1 is expressed in erythroid cells and is required for red cell formation (Fig ...
Some differences exist among the vertebrates, such as c-myb being expressed in ...
Web Search

Immortalization of yolk sac-derived precursor cells - Full text - MIT Libraries
WM Yu, TS Hawley, RG Hawley, CK Qu - Blood, 2002 - bloodjournal.org
... factor, stem cell factor, basic fibroblast growth factor, and interleukin 6. They
also expressed the transcription factors SCL, GATA2, GATA1, PU.1, and c-myb. ...
Cited by 2 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov - all 6 versions »

Expression of alpha4-integrin defines the earliest precursor of hematopoietic cell lineage diverged … - Full text - MIT Libraries
M Ogawa, M Kizumoto, S Nishikawa, T Fujimoto, H … - Blood, 1999 - bloodjournal.org
... Different dilutions of cDNA prepared from sorted cells were subjected to PCR
amplification specific for Gata1, Gata2, Tal1, Lmo2, Myb, and Gapd transcripts. ...
Cited by 35 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Scl is required for dorsal aorta as well as blood formation in zebrafish embryos - Full text - MIT Libraries
LJ Patterson, M Gering, R Patient - Blood, 2005 - bloodjournal.org
... differentiation genes, E1 and alas2, and regulators, gata1, pu.1, c-myb and ikaros,
was never observed in morphants at early stages of PLM development (Figure ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

transcripts including those of the PU. 1 gene - Full text - MIT Libraries
H Okada, T Watanabe, M Niki, H Takano, N Chiba, N … - Oncogene, 1998 - nature.com
... AML1 PEBP2 b/CBF b PEBP2 aA GATA1 GATA2 Ikaros Scl/tal1 PU.1 NFE2 c-Myb ¯k-1
¯k-2/¯t-3 ¯t-1 SCF c-Kit Epo Epo receptor M-CSF M-CSF receptor G-CSF G-CSF ...
Cited by 30 - Web Search - nature.com - ncbi.nlm.nih.gov

Zebrafish: An emerging genetic model for the study of cytokines and hematopoiesis in the era of …
GJ Lieschke - Int. J. Hematol, 2001 - cardenjennings.metapress.com
... U01530 [22,23]; gata2 U18312 and reference 24, NP_032116; gata1 U18311, S04655 ... 4
[59]; ikaros AF092175, NM_006060 [60]; oct1 AF030519, X56230; c-myb P06876 [57 ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genomic structure and refined chromosomal localization of the mouse Ptch2 gene - Full text - MIT Libraries
L Froehlich, Z Liu, DR Beier, B Lanske, FTC Alert - Cytogenetic and Genome Research, 2002 - content.karger.com
... boxes (SP1 elements), and several other elements, including sites for interaction
with AP-1, AP-2, CREB-2, c/EPB , c-Ets-1, c-Myb, Egr-1, GATA1, NF1, NF- B, Oct ...
Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

Runx 3 is required for hematopoietic development in zebrafish - Full text - MIT Libraries
ML Kalev-Zylinska, JA Horsfield, MVC Flores, JH … - Developmental Dynamics, 2003 - doi.wiley.com
... Early Expression of scl, lmo2, and gata1 Is Preserved in runx3-Morpholino Injected
Embryos To further investigate the nature and the time of onset of the ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Haemangioblast commitment is initiated in the primitive streak of the mouse embryo - Full text - MIT Libraries
TL Huber, V Kouskoff, H Joerg Fehling, J Palis, G … - Nature, 2004 - nature.com
... 1d). The non-adherent population expressed the haematopoietic markers H1 and -major
globin, as well as Gata1, c-fms (also known as Csf1r) and Myb (Fig. ...
Cited by 11 - Web Search - nature.com - ncbi.nlm.nih.gov

Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells - Full text - MIT Libraries
H Ohta, A Sawada, JY Kim, S Tokimasa, S Nishiguchi … - J Exp Med, 2002 - jem.org
... gp130, Epo receptor, G-CSF receptor, GM-CSF receptor, c-erbA , c-Mpl, c-jun, c-fos,
c-myc, c-myb, tal1/SCL, AML1, GATA1, GATA2, and PU.1. Expression of none of ...
Cited by 29 - Web Search - intl.jem.org - ncbi.nlm.nih.gov

Critical Review - Full text - MIT Libraries
C Das, S Philip, GH Mahabeleshwar, A Bulbule, GC … - IUBMB Life, 2005 - taylorandfrancis.metapress.com
... CBP mediated acetylation increases the trans-activating capacity of C-Myb (26).
(c) GATA. The transcriptional activator GATA1 also plays an important role in ...
Web Search - taylorandfrancis.metapress.com

GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood … - Full text - MIT Libraries
K Kitajima, M Masuhara, T Era, T Enver, T Nakano - The EMBO Journal, 2002 - embojournal.npgjournals.com
... the transcriptional interaction of GATA-2 and GATA-2/ER with c-Myb was analyzed
(Figure 7B). When a GATA-1 promoter (GATA1-luc) was used, c-Myb inhibited GATA-2 ...
Cited by 20 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 7 versions »

A transcription factor party during blood cell differentiation
MH Sieweke, T Graf - Curr. Opin. Genet. Dev, 1998 - ciml.univ-mrs.fr
... c-Maf can inhibit the synergistic activity of c-Ets-1 and c-Myb on the ... factors:
complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1. ...
Cited by 62 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

Histone modification enzymes: novel targets for cancer drugs
R Kristeleit, L Stimson, P Workman, W Aherne - Expert Opinion on Emerging Drugs, 2004 - dx.doi.org
... p300/CBP p300 CBP 300 260 H2A, H2B, H3, H4 H2A, H2B, H3, H4 Co-activators p53,
c-myb, NF-κB, HMG1, HMG14, GATA1, EKLF, ACTR, SRC1, TIF2, AML1, TFIIE, TFIIF ...
Web Search - extenza-eps.com - ashley-pub.com - ingentaconnect.com - all 8 versions »

Molecular Mechanisms of Megakaryocyte Differentiation - Full text - MIT Libraries
H Schulze, RA Shivdasani - Seminars in Thrombosis and Hemostasis, 2004 - thieme-connect.com
... 986 12 Hitzler JK, Cheung J, Li Y, Scherer SW, Zipursky A. GATA1 mutations in ... A
functional c-myb gene is required for normal murine fetal hepatic hematopoiesis ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Giving rice the time of day. Molecular identification of a major photoperiod sensitivity … - Full text - MIT Libraries
NA Eckardt - Plant Cell, 2000 - plantcell.org
... LHY) and CIRCADIAN CLOCK ASSOCIATED1 (CCA1), which encode similar MYB proteins,
EARLY ... CO encodes a protein showing similarity to GATA1-type zinc finger ...
Web Search - ncbi.nlm.nih.gov

Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in … - Full text - MIT Libraries
AG Muntean, JD Crispino - Blood, 2005 - bloodjournal.org
... Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis. ... P, Kralova
J, Blendinger G, Dvorak M, Zenke M. GATA-1 and c-myb crosstalk during ...
Cited by 1 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Structural organization and classification of the human mucin genes
N Moniaux, F Escande, N Porchet, JP Aubert, SK … - Front Biosci, 2001 - xylian.igh.cnrs.fr
... in mammary epithelial cells (MAF, MGF, MP4, RME, PMR, SpA, and WAP), elements specific
for transcription in hemapoetic cells (BKLF/TEFII, GATA1, v-Myb, c-Myb ...
Cited by 57 - Cached - Web Search - bioscience.org - bioscience.org - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

Uroporphyrinogen III Synthase - Full text - MIT Libraries
GI Aizencang, DF Bishop, D Forrest, KH Astrin, RJ … - J Biol Chem, 2000 - jbc.org
... E47 has been shown to be a DNA binding partner of GATA1 and Tal1 in the ... MYB is a
protein target for binding by the murine c-Maf protein, and this complex has ...
Cited by 16 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish - Full text - MIT Libraries
EC Liao, NS Trede, D Ransom, A Zapata, M Kieran, … - Development, 2002 - dev.biologists.org
... of both primitive and definitive hematopoiesis such as Scl, Lmo2, Gata1, Gata2 and
Flk1 ... for definitive but not primitive hematopoiesis, such as Myb, Kit, Slf ...
Cited by 12 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Giving Rice the Time of Day: Molecular Identification of a Major Photoperiod Sensitivity …
OF FLOWERING - yale.edu
... LHY) and CIRCADIAN CLOCK ASSOCIATED1 (CCA1), which encode similar MYB proteins,
EARLY ... CO encodes a protein showing similarity to GATA1-type zinc finger ...
View as HTML - Web Search

Loss of hspa9b in zebrafish recapitulates the ineffective hematopoiesis of the myelodysplastic … - Full text - MIT Libraries
SE Craven, D French, W Ye, F de Sauvage, A … - Blood, 2005 - bloodjournal.org
... (GL) Whole-mount in situ hybridization for gata1 (GJ) and e3 globin (L) at 33 ... (GH)
Whole-mount in situ hybridization for c-myb + stem cells at 42 hpf in wild ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Oncogenes et leucemies: historique et perspectives
S Gisselbrecht, BG Roussy - M e decine et Science, 2003 - erudit.org
... de la famille Ras, Harvey et Kirsten Ras, des oncogènes nucléaires Myc, Myb, et
de Ets1 ... Ces leucémies présentent des mutations ponctuelles du gène GATA1. ...
Cited by 2 - Cached - Web Search

A transgenic mouse model for non-immune hydrops fetalis induced by the NS1 gene of human parvovirus … - Full text - MIT Libraries
H Chisaka, E Morita, K Murata, N Ishii, N Yaegashi … - J Gen Virol, 2002 - jgv.sgmjournals.org
... Although the GATA1 promoter is known to be activated specifically in erythroid-lineage
cells ... A functional c-myb gene is required for normal murine fetal hepatic ...
Cited by 8 - Web Search - vir.sgmjournals.org - jgv.sgmjournals.org - ncbi.nlm.nih.gov - all 6 versions »

A Placenta-Specific Enhancer of the Human Syncytin Gene - Full text - MIT Libraries
YH Cheng, S Handwerger, S Handwerger - BIOLOGY OF REPRODUCTION, 2005 - biolreprod.org
... Olignucleotide-directed mutagenesis of the SP1, ETS2, MYB ( v-myb myeloblastosis
viral oncogene homolog (avian)) , and GATA1 and GATA2 ...
Web Search - biolreprod.org - ncbi.nlm.nih.gov

NF-kappa B transcription factors are involved in normal erythropoiesis - Full text - MIT Libraries
MY Zhang, SC Sun, L Bell, BA Miller - Blood, 1998 - bloodjournal.org
... nuclear extracts from day 10 BFU-E-derived cells, p50, p52, and p65 were able to
form complexes, which bound to B sites in the promoters of both the c-myb and c ...
Cited by 25 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Effect of transcription-factor concentrations on leukemic stem cells - Full text - MIT Libraries
F Rosenbauer, S Koschmieder, U Steidl, DG Tenen - Blood, 2005 - bloodjournal.org
... key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb. ... Interplay
of pu.1 and gata1 determines myelo-erythroid progenitor cell fate in ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Intron 1 Elements Promote Erythroid-specific GATA-1 Gene Expression - Full text - MIT Libraries
D Seshasayee, JN Geiger, P Gaines, DM Wojchowski - J Biol Chem, 2000 - jbc.org
... at a penultimate stage (1). In addition, in viral myb-ets transformed ... at levels
sufficient to rescue the erythroid differentiation of GATA1-deficient embryonic ...
Cited by 9 - Web Search - jbc.org - ncbi.nlm.nih.gov

In vitro Use of Primary Human Hematopoietic Cells as a Model to Investigate the Regulation of …
V Maguer-Satta, F Alert - Transfusion Medicine and Hemotherapy, 2004 - content.karger.com
... erythroid-specific cytokine erythropoi- etin (EPO)) that permit cellular proliferation
and regulation of lineage-specific genes such as GATA2, c-Myb, and EPO-R ...
Web Search - content.karger.com - dx.doi.org - karger.com