… protein with many targets, is essential for growth and bears some resemblance to the oncogene myb - Full text - MIT Libraries
QD Ju, BE Morrow, JR Warner - Mol. Cell. Biol, 1990 - pubmedcentral.nih.gov
... Saccharomyces cerevisiae, such as ABF1, RAP1, GCN4, and HSF1. There was some homology
between a portion of REB1 and the DNA-binding domain of the oncogene myb. ...
Cited by 34 - Web Search - ncbi.nlm.nih.gov

B-Myb and cyclin D 1 mediate heat shock element dependent activation of the human HSP 70 promoter - Full text - MIT Libraries
H Kamano, KH Klempnauer - Oncogene, 1997 - nature.com
... It is conceiva- ble that B-Myb, in a speci®c manner, activates factors (such as
HSF1) that are normally activated during heat fI ∆3 ∆Ear ∆Apo ∆Fsp ...
Cited by 21 - Web Search - nature.com - ncbi.nlm.nih.gov

Temperature-dependent Modification and Activation of B-MYB - Full text - MIT Libraries
G Santilli, R Schwab, R Watson, C Ebert, BJ Aronow … - J. Biol. Chem, 2005 - jbc.org
... redox modification induced by heat causes a change in electrophoretic mobility of
heat shock factor 1 (HSF1) (37). To assess whether B-MYB could be modified by ...
Web Search - jbc.org

Rapid and reversible relocalization of heat shock factor 1 within seconds to nuclear stress granules - Full text - MIT Libraries
C Jolly, Y Usson, RI Morimoto - Cell, 1999 - dx.doi.org
... nuclear compartment for the temporal regulation and spatial organization of HSF1
activity and ... JC Reed, and S. Ishii p53 Suppresses the c-Myb-induced Activation ...
Cited by 32 - Web Search - pnas.org - pubmedcentral.nih.gov - biochem.northwestern.edu - all 8 versions »

Stress–inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection - Full text - MIT Libraries
RI Morimoto, MG Santoro - Nature Biotechnology, 1998 - nature.com
... Activation of heat shock transcription factor 3 by c-Myb in the absence of cellular
stress. ... Molecular chaperones as HSF1-specific transcriptional repressors. ...
Cited by 121 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

HSF 3 is a major heat shock responsive factor duringchicken embryonic development - Full text - MIT Libraries
Y Kawazoe, M Tanabe, N Sasai, K Nagata, A Nakai - European Journal of Biochemistry, 1999 - content.febsjournal.org
... As HSF3 can specifically bind to and is activated by the proto-oncogene c-myb [25],
and HSF1 cooperates with a signal transducer and activator of transcription ...
Cited by 10 - Cached - Web Search - ejbiochem.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Table I. SUMO targets and SUMOylation functions
RN Transporter - nature.com
... c-Myb Transcriptional activator K499, 523 Reduces c-Myb transcriptional activity ...
HSF1 Heat shock factor K298 Stimulates DNA binding and heat induced HSF1 ...
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Characterization of constitutive HSF2 DNA-binding activity in mouse embryonal carcinoma cells - Full text - MIT Libraries
SP Murphy, JJ Gorzowski, KD Sarge, B Phillips - Mol. Cell. Biol, 1994 - pubmedcentral.nih.gov
... by oligomerization, modification, and rapid translocation of heat shock transcription
factor HSF1. ... SA, Kowenz-Leutz E, Casini T, Graf T, Leutz A. Myb and NF-M ...
Cited by 32 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Involvement of nuclear factor-1 (NF1) binding motif in the regucalcin gene expression of rat kidney …
H Misawa, M Yamaguchi - Molecular and Cellular Biochemistry, 2001 - springerlink.com
... Potential binding sites by HSF1, HSF2, NF1, c-Myb, GATA-2, and HSF are
marked by solid lines above (sense) or below (antisense). ...
Cited by 2 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulation and Function of SUMO Modification - Full text - MIT Libraries
RS Hilgarth, LA Murphy, HS Skaggs, DC Wilkerson, H … - J Biol Chem, 2004 - jbc.org
... to also be important for localization of the transcription factor HSF1 to nuclear ...
LEF, c-Jun, Ah receptor nuclear translocator (ARNT), CEBP , c-Myb, Sp3, IRF-1 ...
Cited by 8 - Web Search - jbc.org - ncbi.nlm.nih.gov

Glycogen Synthase Kinase 3 beta Negatively Regulates Both DNA-binding and Transcriptional Activities … - Full text - MIT Libraries
IJ Xavier, PA Mercier, CM McLoughlin, A Ali, JR … - J Biol Chem, 2000 - jbc.org
... Myc and Myb family members (46). Therefore, it appears that the inhibitory action
of GSK3 may be common to a variety of transcription factors including HSF1. ...
Cited by 30 - Web Search - jbc.org - kinase.uhnres.utoronto.ca - ncbi.nlm.nih.gov - all 5 versions »

A Nuclear Localization Signal Is Essential for Stress-induced Dimer-to-Trimer Transition of Heat … - Full text - MIT Libraries
A Nakai, T Ishikawa - J Biol Chem, 2000 - intl.jbc.org
... however, the activation mechanism of cHSF3 may be similar to that of HSF1 (32 ... cHSF3
is also specifically activated by the c-Myb proto-oncogene product through a ...
Cited by 9 - Web Search - jbc.org - jbc.org - ncbi.nlm.nih.gov

Regulation of the heat shock transcriptional response: cross talk between a family of heat shock … - Full text - MIT Libraries
RI Morimoto - Genes Dev, 1998 - genesdev.org
... even though HSF1 is expressed (Tanabe et al. 1998 ). HSF3 also interacts with other
transcription factors and can be activated by the Myb oncogene, independent ...
Cited by 319 - Web Search - dqb.fc.ul.pt - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcriptional regulation of {alpha} B-crystallin in astrocytes: analysis of HSF and AP1 activation … - Full text - MIT Libraries
MW Head, L Hurwitz, JE Goldman - J Cell Sci, 1996 - jcs.biologists.org
... c-myb and perhaps arachidonic acid each can modulate stress protein expression
(Engelberg et al., 1994; Kanei-Ishii et al., 1994; Jurivich et al., 1994), HSF1 ...
Cited by 19 - Web Search - jcs.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Post-translational modification by the small ubiquitin-related modifier SUMO has big effects on …
G Gill - Curr. Opin. Genet. Dev, 2003 - genetics.biol.ttu.edu
... SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor ...
paper, the authors show that heat shock transcription factor 1, HSF1, is post ...
Cited by 32 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Disruption of the HSF 3 gene results in the severe reduction of heat shock gene expression and loss … - Full text - MIT Libraries
M Tanabe, Y Kawazoe, S Takeda, RI Morimoto, K … - The EMBO Journal, 1998 - embojournal.npgjournals.com
... the myb-mediated growth response (Kanei-Ishii et al., 1997 ). As a stress-responsive
factor, HSF3 is activated by the same stress conditions which induce HSF1, ...
Cited by 33 - Web Search - emboj.org - biochem.northwestern.edu - wwwlib.bionet.nsc.ru - all 8 versions »

Heat shock response and protein degradation: regulation of HSF2 by the ubiquitin-proteasome pathway - Full text - MIT Libraries
A Mathew, SK Mathur, RI Morimoto - Mol. Cell. Biol, 1998 - mcb.asm.org
... In avian cells expressing HSF1 but in which the HSF3 gene is deleted, the ...
protein-protein interaction with the DNA binding domain of the c-Myb proto-oncogene ...
Cited by 65 - Web Search - pubmedcentral.nih.gov - biochem.northwestern.edu - ncbi.nlm.nih.gov - all 5 versions »

Arrest of spermatogenesis in mice expressing an active heat shock transcription factor 1 - Full text - MIT Libraries
A Nakai, M Suzuki, M Tanabe - The EMBO Journal, 2000 - embojournal.npgjournals.com
... Complex formation of HSF3 with c-Myb (Kanei-Ishii et al., 1997) and of HSF1 with
signal transducer and activation of transcription 1 (STAT1) (Stephanou et al ...
Cited by 30 - Web Search - emboj.org - nature.com - pubmedcentral.nih.gov - all 7 versions »

Role of the Heat-Shock Response in the Life and Death of Proteins
BPOFM CHAPERONES - biochem.northwestern.edu
... extreme stress-induced factor activated under non-stress con- ditions by association
with c-Myb, and the expression of which is required for HSF1 activation in ...
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Generation of dominant-negative effects on the heat shock response in Arabidopsis thaliana by … - Full text - MIT Libraries
M Wunderlich, W Werr, F Schoffl - The Plant Journal, 2003 - blackwell-synergy.com
... the heat shock response in transgenic tobacco expressing Arabidopsis HSF1 fusion
proteins ... JJ and Watson, RJ (1996) Interference of Myb transactivation activity ...
Cited by 5 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Histone modifications: Now summoning sumoylation
D Nathan, DE Sterner, SL Berger - Proceedings of the National Academy of Sciences - pnas.org
... factor HSF1 and tumor suppressor p53 (11-13). However, sumoylation most frequently
correlates with decreased transcriptional activity (eg, Elk1, Sp3, c-Myb, ...
Cited by 6 - Web Search - intl.pnas.org - pubmedcentral.nih.gov - dx.doi.org - all 7 versions » - Get it from MIT Libraries

Modification with SUMO - Full text - MIT Libraries
A Verger, J Perdomo, M Crossley - EMBO Reports, 2003 - emboreports.npgjournals.com
... For example, sumoylation of the heat shock factors HSF1 and HSF2 (Goodson et al ... many
diverse transcription factors, such as Sp3, c-Jun, c-Myb, AP2 (activating ...
Cited by 15 - Web Search - nature.com - emboreports.npgjournals.com - nature.com

In vivo growth of a murine lymphoma cell line alters regulation of expression of HSP72 - Full text - MIT Libraries
S Davidson, P Hoj, T Gabriele, RL Anderson - Mol Cell Biol, 1995 - mcb.asm.org
... v-Myb can activate the human hsp72 promoter, this activation being de- pendent on ...
HSP72 synthesis may act by correcting a defect in the HSF1-mediated pathway ...
Cited by 4 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

Glutathione depletion impairs transcriptional activation of heat shock genes in primary cultures of … - Full text - MIT Libraries
K Rokutan, T Hirakawa, S Teshima, S Honda, K Kishi - J Clin Invest, 1996 - jci.org
... by oligomerization, modification, and rapid translocation of heat shock transcription
factor HSF1. ... Reduction of a conserved Cys is essential for Myb DNA-binding ...
Cited by 19 - Web Search - pubmedcentral.nih.gov - jci.org - ncbi.nlm.nih.gov - all 5 versions »

www. labonweb. com Home Help [Feedback][For Subscribers][Archive][Search][Contents] - Full text - MIT Libraries
HS Proteins, C Pathophysiology - J. Cell Sci, 2003 - pnas.org
... Gene Expression and Activity by Heat-Shock Transcription Factor 1 (HSF1) J. Biol ...
Si Matsuzawa, JC Reed, and S. Ishii p53 Suppresses the c-Myb-induced Activation ...
Web Search

MY ACCOUNT| E-ALERTS| SUBSCRIBE| REGISTER| HELP - Full text - MIT Libraries
JST CREST - The EMBO Journal, 1998 - nature.com
... the myb-mediated growth response (Kanei-Ishii et al., 1997). As a stress-responsive
factor, HSF3 is activated by the same stress conditions which induce HSF1, ...
Web Search - nature.com

Heat Shock Factor 1 Represses Transcription of the IL-1 beta Gene through Physical Interaction with … - Full text - MIT Libraries
Y Xie, C Chen, MA Stevenson, PE Auron, SK … - J Biol Chem, 2002 - jbc.org
... NF- B, v-Myb, AP-1, and retinoblastoma protein (36-41). As shown in Fig. 2C, both
full-length NF-IL6 and the bZIP region of NF-IL6 bind to the HSF1-GST fusion ...
Cited by 14 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcriptional activation of a heat shock gene promoter in sunflower embryos: synergism between ABI … - Full text - MIT Libraries
A Rojas, C Almoguera, J Jordano - The Plant Journal, 1999 - blackwell-synergy.com
... has been demonstrated, to our knowledge, in only two cases, both in animal systems:
for HSF3 and c-Myb ( Kanei-Ishii et al. 1997), and for HSF1 and STAT1 ...
Cited by 12 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Noncovalent SUMO-1 Binding Activity of Thymine DNA Glycosylase(TDG) Is Required for Its SUMO-1 … - Full text - MIT Libraries
H Takahashi, S Hatakeyama, H Saitoh, KI Nakayama - J Biol Chem, 2005 - jbc.org
... as has been demonstrated for the androgen receptor, the glucocorticoid receptor,
Sp3, Myb, and C/EBP. Transcription factors such as p53, HSF1, and HSF2 are ...
Cited by 1 - Web Search - jbc.org - ncbi.nlm.nih.gov

Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat … - Full text - MIT Libraries
V Hietakangas, JK Ahlskog, AM Jakobsson, M … - Mol. Cell. Biol, 2003 - mcb.asm.org
... the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription
factor ... HSF1 granules: a novel stress-induced nuclear compartment of human cells ...
Cited by 25 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Regulation of Myeloid Zinc Finger Protein 2 A Transactivation Activity through Phosphorylation by … - Full text - MIT Libraries
H Ogawa, A Murayama, S Nagata, R Fukunaga - J Biol Chem, 2003 - jbc.org
... of several hematopoietic cell-specific genes, such as CD34, c-myb, lactoferin, and ...
transcriptional activators, c-Myc, Elk-1, c-Jun, ATF2, and HSF1 (20-29), as ...
Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

SUMO Substrates and Sites Prediction Combining Pattern Recognition and Phylogenetic Conservation
Y Xue, F Zhou, H Lu, G Chen, X Yao, X Yao - Arxiv preprint q-bio.GN/0409011, 2004 - arxiv.org
... K229 AKME, LKEE, IKAE 1/3; (1/4) c-Myb K503, K527 IKQE, IKQE 2/5; (2/10) Elk-1 ... hnRNP
C K237 IKKE, VKME 0/4; (1/12) HSF1 (Heat shock transcription factor 1) ...
View as HTML - Web Search - arxiv.org - adsabs.harvard.edu

5a-Androstane-3a, 17b-diol activates pathway that resembles the epidermal growth factor responsive …
RA Zimmerman, I Dozmorov, EH Nunlist, Y Tang, X Li … - Prostate Cancer and Prostatic Diseases, 2004 - nature.com
... of several heat shock proteins (HSP; HSPs 27 (X54079), 40 (D49547), 70 (X51757),
and 75 (U12595)), heat shock transcription factor 1 (HSF1; M64673), and cell ...
Cited by 1 - Web Search

Cyclophilins and their possible role in the stress response - Full text - MIT Libraries
L Andreeva, R Heads, CJ Green - International Journal of Experimental Pathology, 1999 - blackwell-synergy.com
... Furthermore, it has been shown that DNA binding activity of the c-Myb protooncogene
transcription factor is negatively regulated by Cyp40 ( Leverson & Ness 1998 ...
Cited by 39 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

The Structure and Function of PKN, a Protein Kinase Having a Catalytic Domain Homologous to That of … - Full text - MIT Libraries
H Mukai - Journal of Biochemistry, 2003 - jb.oupjournals.org
... of the rat c-erbA gene (29), and an exon of the c-myb proto-oncogene ... At least 3 HSFs
have been isolated from mammalian cells, and among them HSF1 functions as ...
Cited by 8 - Web Search - jb.oupjournals.org - jb.oupjournals.org - ncbi.nlm.nih.gov

Galactinol synthase1. A Novel Heat Shock Factor Target Gene Responsible for Heat-Induced Synthesis … - Full text - MIT Libraries
TJ Panikulangara, G Eggers-Schumacher, M … - Plant Physiology, 2004 - plantphysiol.org
... that other HSFs, whose expression depends on the activity of HSF1/HSF3, are ... light-,
abscisic acid-, and ethylene-responsive elements and a MYB recognition site ...
Web Search - plantphysiol.org - ncbi.nlm.nih.gov

Plant responses to drought, salinity and extreme temperatures: towards genetic engineering for …
W Wang, B Vinocur, A Altman - Planta, 2003 - springerlink.com
... 2002 HSF1 and HSF3 A. thaliana JH Lee et al. 1995; Prändl et al. ... Most of these TFs
belong to a few large multigene families, eg MYB, AP2/EREBP, bZIP and WRKY. ...
Cited by 33 - Web Search - biologie.uni-halle.de - ncbi.nlm.nih.gov - Get it from MIT Libraries

PROTEIN MODIFICATION BY SUMO - Full text - MIT Libraries
ES Johnson - Annual Review of Biochemistry, 2004 - arjournals.annualreviews.org
... the opposite effect on sumoylation of the heat shock transcription factor HSF1,
which must ... transcription factors Elk-1, Sp-3, SREBPs, STAT-1, SRF, c-myb, C/EBPs ...
Cited by 47 - Web Search - soc.annualreviews.org - soc.annualreviews.org - ncbi.nlm.nih.gov

The heat shock response and cytoprotection of the intestinal epithelium - Full text - MIT Libraries
JJ Malago, J Koninkx, JE van Dijk - Cell Stress Chaperones, 2002 - cest.allenpress.com
... DNA-binding proteins called the HSFs (HSF1–4, of which the best known is HSF1). ... Nuclear
and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, Hsp70 ...
Cited by 7 - Web Search - bioone.org - pubmedcentral.nih.gov - apt.allenpress.com - all 7 versions »

A Seed-specific Heat-shock Transcription Factor Involved in Developmental Regulation during … - Full text - MIT Libraries
C Almoguera, A Rojas, J Diaz-Martin, P Prieto- … - J Biol Chem, 2002 - jbc.org
... HSF1 and HSF3 also have other functions in addition to their involvement in
heat-shock ... An example of this is the interaction between c-Myb factor and HSF3 (3 ...
Cited by 4 - Web Search - genetics.biol.ttu.edu - jbc.org - ncbi.nlm.nih.gov

Transcription factors and their genes in higher plants - Full text - MIT Libraries
L Liu, MJ White, TH MacRae - Eur. J. Biochem, 1999 - ejbiochem.org
... For instance, most plant Myb-related proteins have two Myb domains, whereas the
potato MybSt1 (Myb Solanum tuberosum 1) [71] and the Arabidopsis CCA1 [38] each ...
Cited by 40 - Web Search - content.febsjournal.org - blackwell-synergy.com - ingentaconnect.com - all 9 versions »

Structural Organization and Promoter Analysis of Murine Heat Shock Transcription Factor-1 Gene - Full text - MIT Libraries
Y Zhang, S Koushik, R Dai, NF Mivechi - J Biol Chem, 1998 - jbc.org
... 3, is found in chicken and has recently been shown to be activated by c-Myb in the ...
The 5'-end PCR primer used to generate CTF mutation for HSF1 was as follow: 5 ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Full Text View - Full text - MIT Libraries
JJ Malago, JFJG Koninkx, JE van Dijk - Cell Stress & Chaperones - bioone.org
... DNA-binding proteins called the HSFs (HSF1–4, of which the best known is HSF1). ... 1989,
Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53 ...
Web Search - bioone.org

Nuclear and unclear functions of SUMO - Full text - MIT Libraries
JS Seeler, A Dejean - Nature Reviews Molecular Cell Biology, 2003 - nature.com
... The phosphorylation of a specific serine residue of HSF1 precedes sumoylation, thereby
providing an excellent example for the interplay between two types of ...
Cited by 98 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the … - Full text - MIT Libraries
S Maheswaran, C Englert, G Zheng, SB Lee, J Wong, … - Genes Dev, 1998 - genesdev.org
... homolog, HSF3, appears to bind directly to the product of c-myb and mediate ... WT1,
we were unable to distinguish between the known family members HSF1 and HSF2 ...
Cited by 39 - Web Search - genesdev.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Identification of novel heat shock factor-dependent genes and biochemical pathways in Arabidopsis … - Full text - MIT Libraries
W Busch, M Wunderlich, F Schoffl - The Plant Journal, 2005 - blackwell-synergy.com
... had no detectable effects on the HS response, only hsfA1a/hsfA1b (hsf1/3) double ...
factor superfamily (74 members; Eulgem et al., 2000) and the MYB family (133 ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Promoter specificity and deletion analysis of three heat stress transcription factors of tomato
E Treuter, L Nover, K Ohme, KD Scharf - Mol. Gen. Genet, 1993 - springerlink.com
Page 1. Mol Gen Genet (1993) 240:113-125 © Springer-Verlag 1993 Promoter specificity
and deletion analysis of three heat stress transcription factors of tomato ...
Cited by 36 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Origin and evolution of avian microchromosomes - Full text - MIT Libraries
DW Burt, FTC Alert - Cytogenetic and Genome Research, 2002 - content.karger.com
... MYC 2 8 15 24 Schmid et al. 2000 HSF1 2 8 15 Schmid et al. 2000 TRHR 2 8 15 Schmid
et al. ... 2000 ME1 3 6 9 Schmid et al. 2000 MYB 3 6 10 23 Schmid et al. 2000 ...
Cited by 21 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

BMC Genomics - Full text - MIT Libraries
J Besco, A Frostholm, MC Popesco, AHM Burghes, A … - BMC Genomics, 2001 - biomedcentral.com
Page 1. ...
View as HTML - Web Search - dx.doi.org - pubmedcentral.nih.gov - bmc.ub.uni-potsdam.de - all 9 versions »

SUMO: ligases, isopeptidases and nuclear pores - Full text - MIT Libraries
F Melchior, M Schergaut, A Pichler - Trends Biochem. Sci, 2003 - fhcrc.org
... Positive regulation of sumoylation by phosphorylation has recently been
shown for the SUMO target Hsf1. Hieta- kangas et al. found ...
Cited by 40 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov