Human c-myb Protooncogene: Nucleotide Sequence of cDNA and Organization of the Genomic Locus - Full text - MIT Libraries
B Majello, LC Kenyon, R Dalla-Favera - Eur. J. Biochem, 2003 - pnas.org
... J. WANG, and SC LU The role of c-Myb and Sp1 in the up-regulation of methionine
adenosyltransferase 2A gene expression in human hepatocellular carcinoma FASEB J ...
Cited by 46 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

B-Myb protein in cellular proliferation, transcription control, and cancer: Latest developments - Full text - MIT Libraries
A Sala, R Watson - Journal of Cellular Physiology, 1999 - doi.wiley.com
... Mutagenesis of SP1 sites of the B-Myb promoter abolishes B-Myb response, and B-Myb
and SP1 cooperatively activate the reporter vectors (Sala et al., in press). ...
Cited by 25 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Effect of tumor suppressors on cell cycle-regulatory genes: RB suppresses p34 cdc2 expression and … - Full text - MIT Libraries
M Yamamoto, M Yoshida, K Ono, T Fujita, N Ohtani- … - Exp. Cell Res, 1994 - ncbi.nlm.nih.gov
... that the promoter region of the p34cdc2 gene contains putative E2F-like binding
sites which are recognized by Rb and binding sites for c-myb, Sp1, and ATF, and ...
Cited by 46 - Web Search

The v-Rel oncoprotein increases expression from Sp1 site-containing promoters in chicken embryo …
S Sif, AJ Capobianco, TD Gilmore - Oncogene, 1993 - ncbi.nlm.nih.gov
... However, v-Ras and v-Src (but not v-Myb) induced increases in transcription from
the reporter plasmid containing Sp1 sites to the same extent as v-Rel, but ...
Cited by 24 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

CCAAT/Enhancer-binding Proteins(C/EBP) beta and delta Activate Osteocalcin Gene Transcription and … - Full text - MIT Libraries
S Gutierrez, A Javed, DK Tennant, M van Rees, M … - J Biol Chem, 2002 - jbc.org
... For example, Ets-1, c-Myb, Sp1, and C/EBP, together with Runx factors, stimulate
the transcription of hematopoietic and osteogenic genes (13, 14, 23, 42-44 ...
Cited by 39 - Web Search - ncbi.nlm.nih.gov

The role of c-Myb and Sp 1 in the up-regulation of methionine adenosyltransferase 2 A gene … - Full text - MIT Libraries
H YANG, ZZHI HUANG, J WANG, SC LU - The FASEB Journal, 2001 - fasebj.org
... The role of c-Myb and Sp1 in the up-regulation of methionine adenosyltransferase
2A gene expression in human hepatocellular carcinoma. ...
Cited by 3 - Web Search - dx.doi.org - fasebj.org - ncbi.nlm.nih.gov

Repression of the c-myb gene by WT 1 protein in T and B cell lines. - Full text - MIT Libraries
S McCann, J Sullivan, J Guerra, M Arcinas, LM … - J Biol Chem, 1995 - jbc.org
... Similar results were obtained in the DHL-9 cell line (Fig. 7D). Figure 7:
Cotransfection of WT1, EGR-1, and Sp1 with the c-myb promoter constructs. ...
Cited by 19 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Physical interaction between retinoic acid receptor and the oncoprotein Myb inhibits retinoic acid- … - Full text - MIT Libraries
E Pfitzner, J Kirfel, P Becker, A Rolke, R Schuele - Biochemistry, 1998 - dx.doi.org
... and S. Kojima Physical Interaction Between Retinoic Acid Receptor and Sp1: Mechanism
for ... J. Kralova, P. Pajer, Z. Kozmik, and M. Dvorak Myb-interacting Protein ...
Cited by 18 - Web Search - pnas.org - pubmedcentral.nih.gov - ukl.uni-freiburg.de - all 7 versions »

B-Myb acts as a repressor of human COL1A1 collagen gene expression by interacting with Sp1 and CBF … - Full text - MIT Libraries
L CICCHILLITTI, SA JIMENEZ, A SALA, B SAITTA, B … - Biochem. J, 2004 - bj.portlandpress.com
... However, we found that B-Myb decreases Sp1 and CBF binding for their ... region [25].
Furtermore, we performed gel shift assays using B-Myb, Sp1 and CBF specific ...
Cited by 3 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

The Human Tissue Inhibitor of Metalloproteinases(TIMP)-1 Gene Contains Repressive Elements within … - Full text - MIT Libraries
G Dean, DA Young, DR Edwards, IM Clark - J Biol Chem, 2000 - jbc.org
... This revealed protection across a sequence containing consensus binding
sites for the transcription factors c-Myb, Sp1, and c-Ets. ...
Cited by 12 - Web Search - jbc.org - ncbi.nlm.nih.gov

Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter - Full text - MIT Libraries
Z Wang, S Melmed - Endocrinology, 2000 - endo.endojournals.org
... Database searching demonstrated several potential transcription factor-binding sites,
including Sp1, activating protein-4, and c-Myb, within -313 nt to 1 nt of ...
Cited by 10 - Web Search - endo.endojournals.org - ncbi.nlm.nih.gov

[CITATION] … (PARC) stimulates tyrosine phosphorylation, activation of Sp1, Smad 3/4 and c-Myb, and production of …
SP Atamas, IG Luzina, J Choi, N Tsymbalyuk, B … - Arthritis Rheum, 2002
Cited by 3 - Web Search - Get it from MIT Libraries

SV 40 large T antigen transactivates the human cdc 2 promoter by inducing a CCAAT box binding factor … - Full text - MIT Libraries
H Chen, J Campisi, R Padmanabhan - J Biol Chem, 1996 - jbc.org
... The human cdc2 promoter contains consensus binding sites for several cellular
transcription factors, including ATF, c-Myb, Sp1, E2F, and CCAAT box binding ...
Cited by 18 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Activation of human B-MYB by cyclins - Full text - MIT Libraries
A Sala, M Kundu, I Casella, A Engelhard, B … - Proc. Natl Acad. Sci. USA, 1997 - dx.doi.org
... and M. Mudryj Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription ...
The highly conserved DNA-binding domains of A-, B- and c-Myb differ with ...
Cited by 52 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Combinatorial regulation of the murine RAG-2 promoter by Sp1 and distinct lymphocyte-specific … - Full text - MIT Libraries
GA Miranda, M Villalvazo, Z Galic, J Alva, R … - Mol. Immunol, 2002 - ingentaconnect.com
... Although BSAP and c-Myb were deemed necessary for lymphocyte-specific ... DNA binding
assays demonstrated that this element was specifically recognized by Sp1. ...
Cited by 4 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Growth factor-induced promoter activation of murine phospholipase C delta 4 gene - Full text - MIT Libraries
K Fukami, K Takenaka, K Nagano, T Takenawa - European Journal of Biochemistry, 2000 - content.febsjournal.org
... the PLC 4 activation pathway, but there is still a possibility that they affect
transcription when present in combination, because deletion of c-Myb, Sp1 plus c ...
Cited by 8 - Cached - Web Search - ejbiochem.org - blackwell-synergy.com - ingentaconnect.com - all 7 versions »

Promoter of TRAIL-R2 gene
T Yoshida, T Sakai - Vitam Horm, 2004 - ncbi.nlm.nih.gov
... Computer analysis shows putative transcription factor binding sites such as
c-Ets, AML-1a, c-Myb, Sp1, and GATA-1 in TRAIL-R2 promoter. ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

[CITATION] B-MYB autoregulates its own promoter through the SP1-binding site - Full text - MIT Libraries
A Sala, B Saitta, P DeLuca, M Cervellera, I … - Oncogene, 1999
Cited by 1 - Web Search

Effect of cysteamine on redox-sensitive thiol-containing proteins in the duodenal mucosa - Full text - MIT Libraries
T Khomenko, X Deng, MR Jadus, S Szabo - Biochem Biophys Res Commun, 2003 - panomics.com
... compared to the initial elevation but, at the same time, DNA binding of
c-Myb and Sp1 was markedly elevated. In separate experiments ...
Cited by 2 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Transactivation of the GATA-1 promoter by a myb-ets-containing mouse retrovirus is mediated by CACCC …
L Sun-Hoffman, RE Aurigemma, B Sun, SK Ruscetti - Oncogene, 1996 - ncbi.nlm.nih.gov
... Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Retroviridae Proteins,
Oncogenic; Trans-Activators; Transcription Factor, Sp1; Transcription Factors; ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Murine macrophage mannose receptor promoter is regulated by the transcription factors PU. 1 and SP1 - Full text - MIT Libraries
Q Eichbaum, D Heney, D Raveh, M Chung, M Davidson, … - Blood, 1997 - bloodjournal.org
... site. Transcription factor binding sites contained within this sequence
include PU.1, Sp1, ETS, GATA, and MYB motifs. Serial 100 ...
Cited by 34 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

… nuclear differentiation antigen promoter: Evidence for the role of Sp 1 and not of c-Myb or PU. 1 … - Full text - MIT Libraries
WY Kao, JA Briggs, MC Kinney, RA Jensen, RC Briggs - Journal of Cellular Biochemistry, 1997 - doi.wiley.com
... Cell Nuclear Differentiation Antigen Promoter: Evidence for the Role of Sp1 and
Not of c-Myb or PU.1 in Myelomonocytic Lineage-Specific Expression ...
Cited by 10 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcriptional regulation of myelopoiesis
AD Friedman - Int J Hematol, 2002 - cardenjennings.metapress.com
... granulocytes mim-1 C/EBPs, c-Myb Myeloperoxidase (MPO) C/EBPs, PU.1, CBF, c-Myb
Neutrophil elastase (NE) C/EBPs, PU.1/GABP, CBF, c-Myb, Sp1 Myeloblastin (MBN) C ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulation of the cyclin D1 and cyclin A1 promoters by B-Myb is mediated by Sp1 binding sites. - Full text - MIT Libraries
T Bartusel, S Schubert, KH Klempnauer - Gene, 2005 - ncbi.nlm.nih.gov
... Our data show that the C-terminal domain of B-Myb is required for the activation
of the cyclin D1 promoter and that this part of B-Myb interacts with Sp1. ...
Web Search

Isolation and characterization of the human A-myb promoter: regulation by NF-Y and Sp1 - Full text - MIT Libraries
M Introna, J Golay - Oncogene, 2000 - nature.com
... a) or Sp1- II oligonucleotide (b) (lanes 1). The indicated unlabelled competitor
oligos were added at 100 fold molar excess (lanes 2 ± 4): I: A- myb Sp1-I; II ...
Web Search

Sp1 and C/EBP are necessary to activate the lactoferrin gene promoter during myeloid differentiation - Full text - MIT Libraries
A Khanna-Gupta, T Zibello, C Simkevich, AG … - Blood, 2000 - bloodjournal.org
... compartment, several granulocyte-macrophage-specific genes are regulated by
combinations of the transcription factors C/EBP, PU.1, c-Myb, AML-1, and Sp1, 9 ...
Cited by 25 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

c-Myb-binding Sites Mediate G/S-associated Repression of the Plasma Membrane Ca 2-ATPase-1 Promoter - Full text - MIT Libraries
T Afroze, M Husain - J Biol Chem, 2000 - jbc.org
... Also shown are key restriction endonuclease sites, two Myb-binding sites, SP1 and
CAAT box sites, as well as the positions and lengths of single stranded DNA ...
Cited by 14 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Myb binding sites within the N-ras promoter repress transcription - Full text - MIT Libraries
B Ganter, JS Lipsick - Oncogene, 1997 - nature.com
... Downstream of the proposed Myb sites several Sp1-binding sites are found (Paciucci
and Pellicer, 1991) which are characteristic of growth control genes. ...
Cited by 9 - Web Search - stanford.edu - nature.com - ncbi.nlm.nih.gov

S-Adenosylmethionine: a control switch that regulates liver function - Full text - MIT Libraries
JM MATO, FJ Corrales, SC Lu, MA Avila - The FASEB Journal, 2002 - fasebj.org
... analysis (61) . These protected sites (-354 to -312 and -73 to -28) contain
consensus binding sites for c-Myb and Sp1. Mutation of ...
Cited by 28 - Web Search - fasebj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 … - Full text - MIT Libraries
G Watanabe, C Albanese, RJ Lee, A Reutens, G Vairo … - Mol. Cell. Biol, 1998 - mcb.asm.org
... cyclin D1 promoter reporter constructs (1, 70), the wild-type B-Myb promoter reporter ...
The cyclin D1 promoter Sp1 site between 127 and 99 was deleted by PCR ...
Cited by 84 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Effects of B-Myb on Gene Transcription - Full text - MIT Libraries
LR Johnson, TK Johnson, M Desler, TA Luster, T … - J. Biol. Chem, 2002 - jbc.org
... Previous studies have shown that B-Myb can interact indirectly with Sp1 and function
through Sp1 cis-regulatory elements (7). To test the role of the Sp1 sites ...
Cited by 6 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3 - Full text - MIT Libraries
M Tone, MJ Powell, Y Tone, SA Thompson, H Waldmann - J Immunol, 2000 - jimmunol.org
... myb promoter (24). Furthermore, the transcription factors Sp1 and Egr-1
also bind to this c-myb element (24). We wondered whether ...
Cited by 58 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 6 versions »

The Pro-apoptotic Protein Bim Is a Convergence Point for cAMP/Protein Kinase A- and Glucocorticoid- … - Full text - MIT Libraries
L Zhang, PA Insel - J Biol Chem, 2004 - www-insel.ucsd.edu
... It is possible that cAMP/PKA regulates Bim expression by c-Myb or SP1. Farrar et
al. (37) found that 8-Br-cAMP stimulated c-Myb mRNA accumulation. ...
Cited by 3 - View as HTML - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The myeloid-cell-specific c-fes promoter is regulated by Sp1, PU. 1, and a novel transcription … - Full text - MIT Libraries
A Heydemann, G Juang, K Hennessy, MS Parmacek, MC … - Mol. Cell. Biol, 1996 - mcb.asm.org
... 10A, lanes 6 and 7). Furthermore, FP4-3 is not affected by Sp1 or AP-1
oligonucleotides or by antibodies to PU.1, Myb, Elf-1, Fos, or Jun (Fig. ...
Cited by 52 - Web Search - uphs.upenn.edu - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Transcription factor Sp1 is essential for early embryonic development but dispensable for cell … - Full text - MIT Libraries
M Marin, A Karis, P Visser, F Grosveld, S … - Cell, 1997 - dspace.ubib.eur.nl
... reductase Sp1 was one of the first eukaryotic transcription factors (DHFR)
(Lin et al., 1996) and b-myb (Zwicker et al., 1996). ...
Cited by 172 - View as HTML - Web Search - ep.eur.nl - ncbi.nlm.nih.gov - all 5 versions »

Promoter structure and transcription initiation sites of the human death receptor 5/TRAIL-R2 gene - Full text - MIT Libraries
T Yoshida, A Maeda, N Tani, T Sakai - FEBS Lett, 2001 - genomics10.bu.edu
... tential transcription regulatory factor binding sites that might transcriptionally
regulate DR5 gene expression, such as c-Ets 2, AML-1a, c-Myb, Sp1 and GATA-1 ...
Cited by 16 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

… HERV-H human endogenous retrovirus contain binding sites for transcriptional regulation by the Myb … - Full text - MIT Libraries
N de Parseval, H Alkabbani, T Heidmann - J. Gen. Virol, 1999 - vir.sgmjournals.org
... Consensus Myb binding sites are in tinted boxes and the previously identified
Sp1 binding sites are in untinted boxes. Restriction ...
Cited by 8 - Web Search - vir.sgmjournals.org - jgv.sgmjournals.org - ncbi.nlm.nih.gov

Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction - Full text - MIT Libraries
SY Lin, AR Black, D Kostic, S Pajovic, CN Hoover, … - Mol. Cell. Biol, 1996 - mcb.asm.org
... The involvement of TATA-less genes containing E2F and Sp1 binding sites in DNA ... the
DHFR, DNA polymerase , and thymidine kinase genes, c-myc, B-myb, and the ...
Cited by 142 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Full Text View - Full text - MIT Libraries
KM Lele, DJ Wolgemuth - Biology of Reproduction - bioone.org
... for A-myb and Hsf2 binding are located between −4.8 kb and −1.3 kb of the putative
Ccna1 transcriptional start site, and A-myb and Sp1 consensus sequences ...
Web Search - bioone.org

c-myb transactivates the human cyclin A1 promoter and induces cyclin A1 gene expression - Full text - MIT Libraries
C Muller, R Yang, G Idos, N Tidow, S Diederichs, … - Blood, 1999 - bloodjournal.org
... The 3 potential myb binding sites are shown along with the important Sp1 binding
sites and the transcription start sites (marked in bold). ...
Cited by 21 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Targeted treatments for cirrhosis
JA Fallowfield, JP Iredale - Expert Opinion on Therapeutic Targets, 2004 - extenza-eps.com
... factor (PDGF), and endothelin (ET)-1, which stimulate transcription factors such
as NF-κB, c-jun, activation protein (AP)1, c-myb, Sp1, signal transducers and ...
Web Search - ashley-pub.com - dx.doi.org - ingentaconnect.com - all 8 versions »

Structure and biological activity of the transcriptional initiation sequences of the murine c-myb … - Full text - MIT Libraries
PW Sobieszczuk, TJ Gonda, AR Dunn - Nucleic Acids Res, 1989 - pubmedcentral.nih.gov
... used in all cell lines but others are unique; all are located in a region of the
c-myb gene that is GC rich, contains a number of potential Sp1 binding sites ...
Cited by 5 - Web Search - nar.oupjournals.org - ncbi.nlm.nih.gov

trans Activation of gene expression by v-myb - Full text - MIT Libraries
CE Ibanez, JS Lipsick - Mol. Cell. Biol, 1990 - pubmedcentral.nih.gov
... Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell
differentiation ... Full text in PMC]; Courey AJ, Tjian R. Analysis of Sp1 in vivo ...
Cited by 22 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Induction of Human Methionine Adenosyltransferase 2A Expression by Tumor Necrosis Factor {alpha} - Full text - MIT Libraries
H Yang, MR Sadda, V Yu, Y Zeng, TD Lee, X Ou, L … - J. Biol. Chem, 2003 - jbc.org
... and increased expression of c-Myb and Sp1 with subsequent trans-activation of the
MAT2A promoter contribute to transcriptional up-regulation of MAT2A in HCC ( ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cloning of Drosophila transcription factor Adf-1 reveals homology to Myb oncoproteins. - Full text - MIT Libraries
BP England, A Admon, R Tjian - Proc Natl Acad Sci US A, 1992 - pubmedcentral.nih.gov
... is essential for growth and bears some resemblance to the oncogene myb. ... Synergistic
activation by the glutamine-rich domains of human transcription factor Sp1. ...
Cited by 15 - Web Search - pnas.org - ncbi.nlm.nih.gov

The cellular oncogene c-myb can interact synergistically with the Epstein-Barr virus BZLF1 … - Full text - MIT Libraries
SC Kenney, E Holley-Guthrie, EB Quinlivan, D … - Mol. Cell. Biol, 1992 - pubmedcentral.nih.gov
... C, Garcia A, Graf T, Lipsick J. Transformation by v-myb correlates with ... Direct
interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic ...
Cited by 24 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

Association of p107 with Sp1: genetically separable regions of p107 are involved in regulation of E2 … - Full text - MIT Libraries
PK Datta, P Raychaudhuri, S Bagchi - Mol. Cell. Biol, 1995 - mcb.asm.org
... transcription of several cell cycle-regulated genes, including the n-myc, c-myc,
myb, thymidine kinase ... The transcription factor Sp1 plays a major role in the ex ...
Cited by 67 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase - Full text - MIT Libraries
T Haug, F Skorpen, PA Aas, V Malm, C Skjelbred, HE … - Nucleic Acids Research, 1998 - nar.oupjournals.org
... regulatory functions. P A contains putative binding elements for c-Myc,
c-Myb, Ap2 and Sp1 and a CCAAT box (Fig. 1). Mutations in ...
Cited by 30 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Physical interaction between retinoic acid receptor and Sp1: mechanism for induction of urokinase by … - Full text - MIT Libraries
Y Suzuki, J Shimada, K Shudo, M Matsumura, MP … - Blood, 1999 - bloodjournal.org
... of gene expression through interaction between RAR and AP-1, NF-IL6, or Myb has
been reported, 53-55 one may ask whether the RAR/RXR-Sp1 interaction affects ...
Cited by 35 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

c-Myb transcription is activated by protein kinase B (PKB) following interleukin 2 stimulation of T … - Full text - MIT Libraries
A Lauder, A Castellanos, K Weston - Mol Cell Biol, 2001 - mcb.asm.org
... E2F and NF- B sites are underlined and shown in bold, and the putative SP1 site
is overlined. (B) NIH 3T3 cells were transfected with the c-myb- G reporter ...
Cited by 21 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »