Identification of a breakpoint cluster region 3'of the ribophorin I gene at 3q21 associated with the … - Full text - MIT Libraries
K Suzukawa, E Parganas, A Gajjar, T Abe, S … - Blood, 1994 - bloodjournal.org
Page 1. Identification of a Breakpoint Cluster Region 3’ of the Ribophorin
I Gene at 3q21 Associated With the Transcriptional Activation ...
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DNA rearrangements proximal to the EVI1 locus associated with the 3q21q26 syndrome - Full text - MIT Libraries
ER Levy, E Parganas, K Morishita, S Fichelson, L … - Blood, 1994 - bloodjournal.org
... Aberrant expression of the Ecotropic virus integration-l (EVI1) gene, located at
3q26, has been reported in individuals with AML and translocations or ...
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P Segar, KE Richkind, B Haas, P Challinor, P Mowery-Rushton, D De Bauche 2, V Suri 3, M Thangavelu 4
G Genetics, NM Santa Fe, FL Tampa, NY Yonkers, CA … - genzymegenetics.com
... chromosome 3 and immediately distal to MYC on chromosome 8. Possible candidate
genes disrupted by this translocation are EVI1 on 3q26.2 ...
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MDS1/EVI1 enhances TGF-b1 signaling and strengthens its growthinhibitory effect but the leukemia- …
R Sood, A Talwar-Trikha, SR Chakrabarti, G … - Leukemia, 1999 - nature.com
... MDS1/EVI1 enhances TGF- 1 signaling and strengthens its growth-inhibitory effect,
but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3 ...
Cited by 35 - Web Search - ingentaconnect.com - ijp-online.com - ncbi.nlm.nih.gov - all 8 versions » - Get it from MIT Libraries

The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the … - Full text - MIT Libraries
M Stewart, N MacKay, ER Cameron, JC Neil - J. Virol, 2002 - jvi.asm.org
... that longer-range activation can occur, as such effects have been noted at the Mlvi1
and Cb1/Fim3 loci, which appear to activate the c-Myc and Evi1 genes from ...
Cited by 17 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

… of murine CBF 1, a runt domain transcription factor, as a putative Myc collaborator in T cell …
J Neil, M Stewart, A Terry, MH MO’Hara, K Blyth, … - Leukemia, 1999 - nature.com
... 1 we found that very few virus-accelerated CD2-myc tumours involved these loci ...
translocations in myeloid leukaemias (C-terminal fusions with ETO, EVI1, etc) or ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Interaction of EVI 1 with cAMP-responsive Element-binding Protein-binding Protein(CBP) and p 300/CBP … - Full text - MIT Libraries
S Chakraborty, V Senyuk, S Sitailo, Y Chi, G … - J Biol Chem, 2001 - jbc.org
... of pCMV-myc-nuc. This region encodes the first 269 amino acids of EVI1
and was named pCMV-myc-nuc EVI1-269. A larger EVI1 region ...
Cited by 10 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov

Association of 3q21q26 syndrome with different RPN1/EVI1 fusion transcripts - Full text - MIT Libraries
G Martinelli, E Ottaviani, S Buonamici, A Isidori, … - Haematologica-, 2003 - haematologica.org
... 20 In addition to MDS1- EVI1, other members of this protein family include
PRDI-BF1/BLIMPI (a transcription repressor of c-MYC) 21 ...
Cited by 2 - View as HTML - Web Search - ncbi.nlm.nih.gov - haematologica.it - haematologica.it - all 7 versions »

Evi-1 Transforming and Repressor Activities Are Mediated by CtBP Co-repressor Proteins - Full text - MIT Libraries
S Palmer, JP Brouillet, A Kilbey, R Fulton, M … - J Biol Chem, 2001 - jbc.org
... Creation of the Myc-tagged EVI1 expression vector will be described elsewhere.
2 FLAG-tagged mCtBP2 was created by replacing Smad2 ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov

EVI1 REARRANGEMENTS IN MALIGNANT HEMATOPOIESIS
G NUCIFORA - doi.wiley.com
Page 1. CHAPTER 22 EVI1 REARRANGEMENTS IN MALIGNANT HEMATOPOIESIS ... MDS1/EVI1
is ident- ical to EVI1aside from the N-terminus exten- ...
Web Search

The PR Domain of the Rb-binding Zinc Finger Protein RIZ 1 Is a Protein Binding Interface and Is … - Full text - MIT Libraries
S Huang, G Shao, L Liu - J Biol Chem, 1998 - dx.doi.org
... This family includes the MDS1-EVI1 gene inactivated in myeloid leukemia, the
PRDI-BF1/BLIMP1 transcription repressor of c-myc involved in driving B-cell ...
Cited by 30 - Web Search - jbc.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

EVI 1 Promotes Cell Proliferation by Interacting with BRG 1 and Blocking the Repression of BRG 1 on … - Full text - MIT Libraries
Y Chi, V Senyuk, S Chakraborty, G Nucifora - J Biol Chem, 2003 - jbc.org
... To generate EVI1-positive or vector (control) SW13 stable transfectants, the cells
were transfected with pCMV-myc-nuc-HA-EVI1 or the empty vector by calcium ...
Cited by 2 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Advances in targeted therapy for chronic myeloid leukemia
KW Yee, A Keating - Expert Rev Anticancer Ther, 2003 - dx.doi.org
... less frequent acquired abnormalities include deletions of the retinoblastoma tumor
suppressor gene, upregulation of the oncogene c-myc and EVI1 expression and ...
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Assignment of the Ect2 protooncogene to mouse chromosome band 3B by in situ hybridization
S Takai, MV Lorenzi, JE Long, K Yamada, T Miki - Cytogenet Cell Genetics, 1998 - content.karger.com
... EVI1 is a new type of GATA-binding transactivator. Leuke- mia 11:352–358 (1997).
Takahashi E, Hori T, O’Connell P, Leppert M, White R: Mapping of the MYC ...
Cited by 3 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Oligo GEArray® Mouse TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... Col3a1, Fos, Gsc, Igf1, Igfbp3, Il6, Itgb7, Ivl, Jun, Junb, Myc, Pdgfb, Plat ... of
TGF-β superfamily: Bambi, Bmper, Cdkn2b, Cer1, Chrd, Eng, Evi1, Fkbp1b, Fst ...
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Oligo GEArray® Rat TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... Col3a1, Fos, Gsc, Igf1, Igfbp3, Il6, Itgb7, Ivl, Jun, Junb, Myc, Pdgfb, Plat ... the
TGF-β superfamily: Bambi, Cdkn2b, Chrd, Cktsf1b1, Cst3, Eng, Evi1, Fkbp1b, Fmod ...
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Oligo GEArray® Human TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... INHA, INHBA, INHBB, INHBC, PDGFB, PLAU, SERPINE1 Transcription Factors and Regulators:
DLX2, EVI1, FOS, GSC, HIPK2, ID1, ID3, ID4, JUN, JUNB, MYC, NR0B1, RUNX1 ...
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Cytogenetics and molecular genetics of childhood leukemia
SK Ma, TSK Wan, LC Chan - Hematological Oncology, 1999 - doi.wiley.com
... 1 t(1;7)(p34;q34) LCK-TCRb T <1 t(7;9)(q34;q32) TAL2-TCRb T <1 t(7;9)(q34;q34)
TAN1-TCRb T <1 t(8;14)(q24;q11) myc-TCRa/d T ... t(3;21)(q26;q22) EVI1-AML1 1±2 AML ...
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Smad-dependent and Smad-independent pathways in TGF-b family signalling - Full text - MIT Libraries
R Derynck, YE Zhang - Nature, 2003 - nature.com
Page 1. Smad-dependent and Smad-independent pathways in TGF- b family
signalling Rik Derynck 1 & Ying E. Zhang 2 1 Departments of ...
Cited by 172 - Web Search - nature.com - ucsf.edu - ncbi.nlm.nih.gov - all 5 versions »

DETECTION OF MINIMAL RESIDUAL DISEASE IN ACUTE LEUKEMIA
C Karyotyping, CC Techniques - ishapd.org
... T-cell ALL TAL TAL-SIL 5-7 4 t(8;14)(q24;q11) MYC (TCRD)< 1 < 1 ... inv(16)(p13q22)
CBFb-MYHII 3 8-15 inv(3)(q21q26) EVI1 1 < 1 t(9;11)(p21-22;q23) MLL-AF9 1-2 7-9 ...
View as HTML - Web Search - haem.nus.edu.sg

Positive Regulatory Domain I Binding Factor 1 Silences Class II Transactivator Expression in … - Full text - MIT Libraries
N Ghosh, I Gyory, G Wright, J Wood, KL Wright - J Biol Chem, 2001 - jbc.org
... The PR domain of MDS1-EVI1 is a common target of viral insertions and chromosomal ...
domain of Blimp-1 significantly reduced its ability to repress c-myc (25). ...
Cited by 13 - Web Search - jbc.org - ncbi.nlm.nih.gov

Recurrent chromosomal translocations and fusion genes in leukemia-lymphoma cell lines
HG Drexler, RAF MacLeod, A Borkhardt, JWG Janssen - Leukemia, 1995 - ncbi.nlm.nih.gov
... Cultured. Gene Symbols: ALK; AML-1; BCL1; BCL2; BCL6; BLC3; E2A; EAP; EVI1; HOX11;
IL3; LCK; LYL1; LYT10; MDS; MTCP1; MYC; PBX1; RCK; SIS; TAL1; TAL2; TAN1; TTG11 ...
Cited by 40 - Web Search - Get it from MIT Libraries

Molecular cytogenetic analyses of HIG, a novel human cell line carrying t (1; 3)(p36. 3; q25. 3) …
N Hosoya, S Ogawa, T Motokura, A Hangaishi, L Wang … - Int J Hematol, 2003 - cardenjennings.metapress.com
... A discriminating screening is necessary to ascertain EVI1 expression by RT-PCR in
malignant cells ... a chromosome 15 locus at least 72 kb from the c-myc oncogene. ...
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RB and hbrm cooperate to repress the activation functions of E2F1 - Full text - MIT Libraries
D Trouche, C Le Chalony, C Muchardt, M Yaniv, T … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
... O. Coqueret The STAT3 Transcription Factor Is a Target for the Myc and Riboblastoma ...
page Y. Chi, V. Senyuk, S. Chakraborty, and G. Nucifora EVI1 Promotes Cell ...
Cited by 126 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

ZNF198-FGFR1 transforming activity depends on a novel proline-rich ZNF198 oligomerization domain - Full text - MIT Libraries
S Xiao, JG McCarthy, JC Aster, JA Fletcher - Blood, 2000 - bloodjournal.org
... 3 and 6), and then analyzed directly (INP) or immunoprecipitated with anti-HA or
anti-MYC. ... Fusion of ETV6 to MDS1/EVI1 as a result of t(3;12)(q26;p13) in ...
Cited by 25 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Multicolor COBRA-FISH analysis of chronic myeloid leukemia reveals novel cryptic balanced …
A Barbouti, B Johansson, M Hoeglund, N Mauritzson, … - Genes Chromosomes and Cancer, 2002 - doi.wiley.com
... genes (eg, TP53, CDKN2A, and RB1) and oncogenes (eg, RAS and MYC), whereas limited ...
or acute myeloid leukemias (AMLs) (eg, t(3;21)(q26;q22)/CBFA2-EVI1, t(7;11 ...
Cited by 6 - Web Search - lu-research.lub.lu.se - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Establishment of a myeloid leukaemia cell line(Kasumi-4) with t (9; 22; 11)(q 34; q 11; q 13), inv ( … - Full text - MIT Libraries
H Asou, M Eguchi, K Suzukawa, K Morishita, K … - British Journal of Haematology, 1996 - blackwell-synergy.com
... the T-cell receptor -chain gene and sequences on the 3 0 side of MYC. ... K., Parganas,
E., Matsugi, T. & Ihle, JN (1992) Expression of the EVI1 zinc finger gene ...
Cited by 5 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

The tumor suppressor gene RIZ in cancer gene therapy (Review) - Full text - MIT Libraries
R CANOTE, Y DU, T CARLING, F TIAN, Z PENG, SHI … - ONCOLOGY REPORTS, 2002 - 147.52.72.117
... In addition to RIZ and MDS1-EVI1, other cancer genes of the PR/SET superfamily include
PRDM1 (a repressor of c-myc oncogene) (23), ALL1 (24), and MMSET (25). ...
Cited by 2 - View as HTML - Web Search - virology.med.uoc.gr - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Molecular biology of leukemia and lymphoma
AT Look, JR Dowing - Rev Invest Clin, 1994 - ncbi.nlm.nih.gov
... Gene Symbols: AF4; ALL1; E2A; ENL; ETO; EVI1; FEL; HLF; HOX11; HRX; LY1; MLL; MYC;
PBM1; PBX1; PLZF-RAR; PML-RAR; RHOMB1; RHOMB2; SCL; TAL1; TAL2; TCL5; TTG1; TTG2 ...
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Histone methyltransferases, diet nutrients and tumour suppressors - Full text - MIT Libraries
S Huang - Nat. Rev. Cancer, 2002 - nature.com
... of the c-MYC oncogene 38 . In addition to RIZ1, the 1p36.23 region harbours another
PR-domain gene, PRDM16 (MEL1), which is a paralogue of MDS1-EVI1 (Ref. 39). ...
Cited by 14 - Web Search - nature.com

The molecular biology of chronic myeloid leukaemia
JV Melo - Leukemia, 1996 - ncbi.nlm.nih.gov
... RAS and MYC, or of tumour suppressor genes, in particular RB, p53 and p16, or with
the generation of chimeric transcription factors, as in the AML1-EVI1 gene ...
Cited by 72 - Web Search - Get it from MIT Libraries

ASB TransScript
TF Antibodies, P Array, N Antibodies, N Antibodies - avivasysbio.com
... Examples of basic helix-loop-helix containing transcription factors include: Myc,
Max, and ... ARP32265 Anti-EVI1 Human IB, IHC Peptide Affinity 50 µg/100 µg $180 ...
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Core-binding factors in haematopoiesis and leukaemia - Full text - MIT Libraries
NA Speck, DG Gilliland - Nature Reviews Cancer, 2002 - nature.com
... and fluorescence in situ hybridization detect novel chromosomal aberrations, a
recurring involvement of chromosome 21 and amplification of the MYC oncogene in ...
Cited by 60 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

PRDI-BF 1 recruits the histone H 3 methyltransferase G 9 a in transcriptional silencing - Full text - MIT Libraries
I Gy… - Nature Immunology, 2004 - nature.com
... 7. Lin, Y. , Wong, K. & Calame, K. Repression of c-myc transcription by Blimp-1,
an ... Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in ...
Cited by 10 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Diagnostic value of fluorescence in situ hybridization for the detection of genomic aberrations in … - Full text - MIT Libraries
S Froehling, S Kayser, C Mayer, S Miller, C … - Haematologica, 2005 - haematologica.org
... 3q 858_c_9/14EE12 3q26 EVI1, D3S1212 CEPH/ICI +4q F06184 4q22 RZPD ... 8q K19268
8q24 MYC RZPD +11q 785_c_6/856_b_9 11q23 MLL1,THY1 CEPH ...
View as HTML - Web Search - ncbi.nlm.nih.gov

Transcriptional Repression Mediated by the PR Domain Zinc Finger Gene RIZ - Full text - MIT Libraries
M Xie, G Shao, IM Buyse, S Huang - J Biol Chem, 1997 - jbc.org
... It is of considerable interest to determine whether EVI1 and MDS1-EVI1, or RIZ1 ... shown
to be a physiological transcriptional repressor of the c-myc oncogene (15 ...
Cited by 20 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Rearrangements of Chromosome Band 3 q 21 in Myeloid Leukemia
R Wieser - Leukemia & Lymphoma, 2002 - dx.doi.org
... of expression and their clinical implications of the GATA family, stem cell leukemia
gene, and EVI1 in leukemia and ... [62] Dang, C. (1999) “c-myc target genes ...
Cited by 4 - Web Search - taylorandfrancis.metapress.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Identification of a Functionally Impaired Positive Regulatory Domain I Binding Factor 1 … - Full text - MIT Libraries
C Tunyaplin, AL Shaffer, CD Angelin-Duclos, X Yu, … - The Journal of Immunology, 2003 - jimmunol.org
... It represses the transcription of specific target genes, including c-myc, the MHC
class ... are highly analogous to the PRDM2 (RIZ) and PRDM3 (MDS1-EVI1) genes, in ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease … - Full text - MIT Libraries
A Barbouti, M Hoglund, B Johansson, C Lassen, PG … - Cancer Res, 2003 - cancerres.aacrjournals.org
... genes (eg, TP53, CDKN2A, and RB1) and oncogenes (eg, RAS and MYC), but thus ... of
AML-associated translocations/fusion genes, eg, t(3;21)(q26;q22)/RUNX1-EVI1, t(7 ...
Cited by 8 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - lu-research.lub.lu.se - all 5 versions »

PRIMARY SMALL-CELL LUNG CARCINOMAS AND THEIR METASTASES ARE CHARACTERIZED BY A RECURRENT PATTERN OF …
A Schwendel, H Langreck, M Reichel, E Schrock, T … - Cancer - doi.wiley.com
... gene at 3q26, the ETV5 (ets variant gene 5) gene at 3q27-29, the EVI1 gene at ... all
tumors showed an amplification at 2p22-24 which harbors the N-myc oncogene. ...
Cited by 37 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Fusion genes in leukemia: an emerging network
SK Bohlander, FTC Alert - Cytogenet Cell Genet, 2000 - content.karger.com
... D, Hagemeijer A, Van den Berghe H, Marynen P: Fusion of ETV6 to MDS1/EVI1 as a ... C,
Lenoir G, Swam D, Aaronson S, Leder P: Translocation of the c-myc gene into ...
Cited by 13 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Targeted Therapy: For Kids, Too
S TRANSDUCTION - Pediatr Blood Cancer, 2005 - doi.wiley.com
... 8;14 Myc TF Burkitt, ALL 14;18 Bcl2 Anti-apoptotic Follicular lymphoma 4;11
MLL-AF4 TF ALL 8;21 AML1-ETO TF AML, M2 15;17 PML-RAR TF AML, M3 3;21 Evi1-ETO TF ...
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[CITATION] MEDICAL PROGRESS
C LEUKEMIAS, R Factors - THE NEW ENGLAND JOURNAL OF MEDICINE, 1995
... t(8;14)(q24;q32.3) 1 or 2 MYC-IGH fusion B-cell phenotype, predominantly in boys,
L3 ... inv(3)(q21q26) or 1 EVI1 activation Thrombocytosis, abnormal platelets ...
Web Search - indianpediatrics.net - indianpediatrics.net - Get it from MIT Libraries

Friend murine leukemia virus (F-MuLV) induces leukemia by Hoatlin et al 8 suggested that the Fv2 …
RW Friedrich, M Veit, D Eisel, U Friedrich, M Pass … - Leukemia, 1997 - nature.com
... transcribed into differentially spliced mRNAs of 1.9 and 3.7 kb
Fim2/c-fms, Fim3/CB1/Evi1, Fis1, Pim1, c-myc and p53. 11–16 have ...
Web Search - nature.com

Mechanisms of BCR–ABL in the pathogenesis of chronic myelogenous leukaemia - Full text - MIT Libraries
R Ren - Nature Reviews Cancer, 2005 - nature.com
... 118 . Page 4. © 2005 Nature Publishing Group NATURE REVIEWS | CANCER VOLUME 5 |
MARCH 2005 | 175 REVIEWS overexpression of genes such as EVI1 and MYC. ...
Cited by 2 - Web Search - nature.com - ncbi.nlm.nih.gov

Prevalence estimates of recurrent balanced cytogenetic aberrations and gene fusions in unselected …
F Mitelman, F Mertens, B Johansson - GENES, CHROMOSOMES & CANCER, 2005 - doi.wiley.com
Page 1. Prevalence Estimates of Recurrent Balanced Cytogenetic Aberrations and
Gene Fusions in Unselected Patients with Neoplastic Disorders ...
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Activation of a novel proto-oncogene, Frat 1, contributes to progression of mouse T-cell lymphomas - Full text - MIT Libraries
J Jonkers, HC Korswagen, D Acton, M Breuer, A … - The EMBO Journal, 1997 - embojournal.npgjournals.com
... and Ptashne, 1987 ; Sigler, 1988 ), and several proto-oncogenes, such as Evi1 (Perkins
et al., 1991 ), c-myb (Weston and Bishop, 1989 ) and Myc (Blackwell et al ...
Cited by 43 - Web Search - emboj.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... 1 NFAT Q6 Nuclear factor of activated T-cells NMYC 01 N-Myc OCT1 02 ... EVI1 06 Ectopic
viral integration site 1 encoded factor Core should be ACAAGAT not AGAT ...
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Chromosomal Translocations in Hematologic Malignancies
CG Brunstein, SJ Dylla, CM Verfaillie - Current Genomics, 2002 - ingentaconnect.com
Page 1. Current Genomics, 2002, 3, 313-334 313 1389-2029/02 $35.00+.00 © 2002
Bentham Science Publishers Ltd. Chromosomal Translocations ...
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GEArray Q Series Human TGFβ BMP Signaling Pathway Gene Array Cat. No.* Kit Size HS-023-2/HS-023N-2 …
FG Grouping - tebu-bio.com
... b5), ITGB7 (integrin b7), IVL (involucrin), JUN, JUNB, MYC, Goosecoid, PDGFB ... CER1
(cerberus), CHRD (chordin), CKTSF1B1 (gremlin), ENG (endoglin), EVI1 (Evi-1 ...
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