GATA1 Function, a Paradigm for Transcription Factors in Hematopoiesis - Full text - MIT Libraries
R Ferreira, K Ohneda, M Yamamoto, S Philipsen - Mol Cell Biol, 2005 - mcb.asm.org
... To clarify this issue, the authors performed a more detailed analysis of the
interactions between Myc and GATA1 and showed that GATA1 represses transcription ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Extracellular Signal-Regulated Kinase Induces the Megakaryocyte GPIIb/CD41 Gene through MafB/ … - Full text - MIT Libraries
JR Sevinsky, AM Whalen, NG Ahn - Mol. Cell. Biol, 2004 - pubmedcentral.nih.gov
... MYC-GATA1 clearly bound the GATA/Ets motif (demonstrated by supershifting
of GATA1/GPIIb complexes with anti-c-MYC antibodies) (Fig. ...
Cited by 2 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

WT1 and GATA1 expression in myelodysplastic syndrome and acute leukemia
P Patmasiriwat, G Fraizer, H Kantarjian, GF … - Leukemia, 1999 - nature.com
... WT1 and GATA1 expression in myelodysplastic syndrome and acute leukemia ... several genes
expressed in hematopoietic cells (ie CSF-1, TGF -1, RAR , c-myc, and bcl-2 ...
Cited by 18 - Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Ski Negatively Regulates Erythroid Differentiation through Its Interaction with GATA1 - Full text - MIT Libraries
N Ueki, L Zhang, MJ Hayman - Mol Cell Biol, 2004 - mcb.asm.org
... Immunocomplexes were recovered using protein A (for GATA1)/G (for Myc-tagged
protein)-Sepharose for 8 h at 4°C on a rotating wheel, followed by four washings ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

USF/c-Myc enhances, while Yin-Yang 1 suppresses, the promoter activity of CXCR4, a coreceptor for … - Full text - MIT Libraries
M Moriuchi, H Moriuchi, DM Margolis, AS Fauci - J. Immunol, 1999 - jimmunol.org
... 20 µg of pBpuro-c-myc-ER, and either untreated (control) or treated (Myc) with 10 ...
5 B); however, Ab to GATA1, GATA2, or GATA3 did not affect the mobility or ...
Cited by 19 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP - Full text - MIT Libraries
J Vervoorts, JM Luescher-Firzlaff, S Rottmann, R … - EMBO Reports, 2003 - emboreports.npgjournals.com
... relevance of c-MYC acetylation, we tested whether DNA binding is affected, as
acetylation of several transcription factors, including c-MYB, GATA1 and E2F, has ...
Cited by 14 - Web Search - nature.com - qb.fcen.uba.ar - ncbi.nlm.nih.gov - all 6 versions »

Developmental stage− selective effect of somatically mutated leukemogenic transcription factor … - Full text - MIT Libraries
Z Li, FJ Godinho, JH Klusmann, M Garriga-Canut, C … - Nature Genetics, 2005 - nature.com
... Among the genes that are not properly downregulated in Gata1 N megakaryocytes (Fig.
3n), five transcription factors (Myc, Myb, GATA2, PU.1 and ZNFN1A1 (also ...
Cited by 2 - Web Search - nature.com - ncbi.nlm.nih.gov

… by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc … - Full text - MIT Libraries
MJ McConnell, N Chevallier, W Berkofsky-Fessler, … - Mol Cell Biol, 2003 - pubmedcentral.nih.gov
... Growth Suppression by Acute Promyelocytic Leukemia-Associated Protein PLZF Is Mediated
by Repression of c-myc Expression. ... Identification of c-myc responsive.
Cited by 7 - Web Search - dx.doi.org - mcb.asm.org - ncbi.nlm.nih.gov

Direct association of YY-1 with c-Myc and the E-box binding protein in regulation of glycophorin … - Full text - MIT Libraries
JH Zhao, T Inoue, W Shoji, Y Nemoto, M Obinata - Oncogene, 1998 - nature.com
... of the b-globin gene, multiple nuclear factor binding sites including GATA1 and
NF ... regulates glycophorin gene in MEL cells, we are interested in c-Myc because YY ...
Cited by 4 - Web Search - nature.com - ncbi.nlm.nih.gov

Myc Target in Myeloid Cells-1, a Novel c-Myc Target, Recapitulates Multiple c-Myc Phenotypes - Full text - MIT Libraries
X Yin, L Grove, K Rogulski, EV Prochownik - J Biol Chem, 2002 - jbc.org
... 7). The MT-MC1 Promoter Is a Direct c-Myc Target—We cloned and ... Multiple binding sites
for the hematopoietic-specific transcrip- tion factors GATA1–3, TCF-II ...
Cited by 2 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Chromosomal Abnormalities, Cancer and Mouse Models: The Critical Role of Translocation-Associated …
WIS CANCER, IOF ONCOGENES - Current Genomics, 2000 - ingentaconnect.com
... Fibrosarcoma (14%) MT-c-myc C57BL/6 Normal GATA1 pr -c-MYC FVB/N Erythroleukemia
t(14;18)(q32;q21) FL bc12-Ig C57BL/6 Follicular lym pr oliferation ...
Web Search

Terminal differentiation in vitro of patient-derived post-TMD megakaryoblastic AML cells - Full text - MIT Libraries
CF Classen, A Gnekow, KM Debatin - Annals of Hematology, 2003 - springerlink.com
... Recently, mutations of the GATA1 transcription factor have been identified in ...
downregulation of erythroid antigens, going along with downregulation of c-myc. ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

research paper Microarray transcript profiling distinguishes the transient from the acute type of … - Full text - MIT Libraries
S McElwaine, C Mulligan, J Groet, M Spinelli, A … - British Journal of Haematology, 2004 - blackwell-synergy.com
... It has been shown that concomitant induction of c-MYC expression completely abolishes
the GATA1-mediated increase in CDKN2C transcription (Rylski et al, 2003). ...
Web Search

GP0334 TRANSCRIPTION FACTORS
POFT FACTOR, GELSA EMSA, GELSA EMSA - kcl.ac.uk
... Oct1, Oct2 2. PROLINE-rich CTF/N1 3. SERINE/THREONINE-rich GATA1 4. ACIDIC ... CO-REPRESSORS
mediate active repression 1.C-MYC/MAX heterodimers forms an activator. ...
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Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU. 1 - Full text - MIT Libraries
F Rosenbauer, K Wagner, JL Kutok, H Iwasaki, MM Le … - Nature Genetics, 2004 - nature.com
... Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down Syndrome ... Article |
PubMed | ChemPort |; Marcu, KB, Bossone, SA & Patel, AJ myc function and ...
Cited by 13 - Web Search - nature.com - ncbi.nlm.nih.gov - origin.www.nature.com

Microarray transcript profiling distinguishes the transient from the acute type of megakaryoblastic … - Full text - MIT Libraries
S McElwaine, C Mulligan, J Groet, M Spinelli, A … - British Journal of Haematology, 2004 - ingentaconnect.com
... The TMD and AMKL blasts are morphologically and immuno-phenotypically identical,
and have the same acquired mutations in GATA1. ... RNA utiliz ation GATA1 exon 2 ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

SUMO-1 Modification Activated GATA 4-dependent Cardiogenic Gene Activity - Full text - MIT Libraries
J Wang, X Feng, RJ Schwartz - J Biol Chem, 2004 - jbc.org
... In striking contrast to studies of GATA1 and GATA2, SUMO modification resulted in
enhanced GATA4 ... Myc-tagged full-length mouse GATA4 was described (42). ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Semaphorin3a1 regulates angioblast migration and vascular development in zebrafish embryos - Full text - MIT Libraries
W Shoji, S Isogai, M Sato-Maeda, M Obinata, JY … - Development, 2003 - dev.biologists.org
... hpf (F). gata1 expression is normal in yot embryos (G) and in hsp70: gfp sema3a1
myc transgenic embryos at 25 hpf following heat induction at 15 hpf (H). Scale ...
Cited by 18 - Web Search - dx.doi.org - dev.biologists.org - ncbi.nlm.nih.gov

Vegfc is required for vascular development and endoderm morphogenesis in zebrafish - Full text - MIT Libraries
EA Ober, B Olofsson, T Maekinen, SW Jin, W Shoji, … - EMBO Reports, 2004 - emboreports.npgjournals.com
... to estimations from reducing SDS–PAGE analysis without the myc tag) zVegfc ...
knock-down embryos did not exhibit any discernible difference in gata1 (Detrich ...
Cited by 5 - Web Search - nature.com - emboreports.npgjournals.com - ncbi.nlm.nih.gov

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5 - Full text - MIT Libraries
AOP Nature - Nature, 2003 - nature.com
... are expressed predominantly in haematopoietic cells, and heterozygous mutations
of GATA1 and GATA3 ... generated by PCR and cloned into pcDNA3.1-N-Myc and pcDNA3.1 ...
Web Search - nature.com

Oligo GEArray® Human Hematopoietic Stem Cells and Hematopoiesis Microarray
S Conditions - search.cosmobio.co.jp
... CD86, CEBPE, CEBPG, EGR1, ETS1, ETV6, GATA1, GATA2, GFI1, HDAC4, HDAC5, HDAC7A,
HDAC9, HOXB4, IFI16, IL31RA, IRF4, IRF8, KLF6, LEF1, MAFB, MYC, NCOA6, NFYA ...
View as HTML - Web Search

JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic … - Full text - MIT Libraries
TA Chatila, F Blaeser, N Ho, HM Lederman, C … - J Clin Invest, 2000 - jci.org
... The mouse scurfy (sf) mutation is tightly linked to Gata1 and Tfe3 on the ... Human
N-myc is closely related in organization and nucleotide sequence to c-myc. ...
Cited by 66 - Web Search - jci.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

The transcriptional co-activator P/CAF potentiates TGF-ß/Smad signaling - Full text - MIT Libraries
S Itoh, J Ericsson, J Nishikawa, CH Heldin, P ten … - Nucleic Acids Res, 2000 - nar.oupjournals.org
... a supershifted band upon addition of a Myc antibody, which recognizes 6x Myc–P/CAF ...
has been reported for p300 following acetylation of p53 and GATA1 (25,26,50 ...
Cited by 25 - Web Search - nar.oupjournals.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Oncogenes et leucemies: historique et perspectives
S Gisselbrecht, BG Roussy - M e decine et Science, 2003 - erudit.org
... the breackpoints of chromosome rearrangements in human malignancies, such as the
MYC gene in ... playing a key role in hematopoiesis such as C/EBPα, GATA1 and AML1 ...
Cited by 2 - Cached - Web Search

Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle-and … - Full text - MIT Libraries
MP Cosma, T Tanaka, K Nasmyth - Cell, 1999 - tetrad.ucsf.edu
... Ash1p has GATA1-like zinc fingers (Bo- bola et al., 1996; Sil and Herskowitz ... Figure
3. HO Expression and Association of Swi4-Myc with URS2 after Release from ...
Cited by 314 - View as HTML - Web Search - 150.164.24.201 - molbio.ku.dk - cmm.ucsd.edu - all 12 versions »

scientificreport - Full text - MIT Libraries
EA Ober, B Olofsson, T Maekinen, SW Jin, W Shoji, … - EMBO reports, 2004 - nature.com
... knock-down embryos did not exhibit any discernible difference in gata1 (Detrich
et al ... includes an immunoglobulin k signal sequence and a C-terminal Myc epitope. ...
Web Search - nature.com

ChIP-chip: considerations for the design, analysis, and application of genome-wide chromatin … - Full text - MIT Libraries
MJ Buck, JD Lieb - Genomics, 2004 - stat.ohio-state.edu
... Initial ChIP-chip experiments identified binding sites for the c-Myc, Max, Gata1,
E2F, and Rb transcrip- tion factors in cultured human cells [18,20–22]. ...
Cited by 20 - View as HTML - Web Search - mbi.osu.edu - papakilo.icmb.utexas.edu - bio.unc.edu - all 9 versions »

Proliferating cell nuclear antigen (PCNA) as a proliferative marker during embryonic and adult …
AYH Leung, JCK Leung, LYY Chan, ESK Ma, TTF Kwan, … - springerlink.com
... In conclusion, we demonstrated the use of transgenic fli1-eGFP and gata1-eGFP zebrafish
in ... Lin S, Prochownik E, Trede NS, Zon LI, Look AT (2003) Myc-induced T ...
Web Search

Regulation of E 2 A Activities by Histone Acetyltransferases in B Lymphocyte Development - Full text - MIT Libraries
C Bradney, M Hjelmeland, Y Komatsu, M Yoshida, TP … - J Biol Chem, 2003 - jbc.org
... A, Myc-E2A was immunoprecipitated from transfected 293T cells. ... For example, the
acetylation of p53 and GATA1 leads to an increase in sequence-specific DNA ...
Cited by 15 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

In Silico Identification of Regulatory Elements of GRIN 1 Genes
MK Mejia-Guerra, LR Lareo - Omics A Journal of Integrative Biology, 2005 - dx.doi.org
... Position 800 to 700 MEF2 Bsap, SRF- ARNT- HMG-IY, AGL3, nMyc SQUA Max- Myc- Max,
ARNT- nMyc ... HNF-3b (2 copies) 700 to 600 GATA1, GATAX, CdxA SRY Mkx-2 ...
Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in … - Full text - MIT Libraries
AG Muntean, JD Crispino - Blood, 2005 - bloodjournal.org
... in a new window], Figure 1. Characterization of neo HS Gata1 knockdown megakaryocytes. ...
Notably, qRT-PCR analysis demonstrated that c-myc and c-myb were changed ...
Cited by 1 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Expression profiling of CD34 hematopoietic stem/progenitor cells reveals distinct subtypes of … - Full text - MIT Libraries
Z Qian, AA Fernald, LA Godley, RA Larson, MM Le … - N. Engl. J. Med, 2005 - dx.doi.org
... control (CCNA2, CCNE2, CDC2), checkpoints (BUB1), or growth (MYC), and loss of ... of
transcription factors involved in early hematopoiesis (TAL1, GATA1, and EKLF ...
Cited by 21 - Web Search - pnas.org - pubmedcentral.nih.gov - fgf.bsd.uchicago.edu - all 7 versions »

Targets of the transcriptional repressor oncoprotein Gfi-1 - Full text - MIT Libraries
Z Duan, M Horwitz - Proceedings of the National Academy of Sciences, 2003 - pnas.org
... Myc epitope-tagged rat Gfi-1 was synthesized in vitro by using ... GATA1 transcription
factor is indispensable for erythroid and megakaryocyte development (29, 30 ...
Cited by 9 - Web Search - pnas.org - dx.doi.org - ncbi.nlm.nih.gov

Alternative Translation Initiation Site Usage Results in Two Functionally Distinct Forms of the GATA … - Full text - MIT Libraries
R Calligaris, S Bottardi, S Cogoi, I Apezteguia, C … - Proceedings of the National Academy of Sciences - pnas.org
... Kempski, OA Haas, and S. Izraeli Mutations in exon 2 of GATA1 are early ... MAPPING THE
FUNCTIONAL DOMAINS INVOLVED IN DOWN-REGULATION OF THE c-myc PROTOONCOGENE J ...
Cited by 33 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

HOX and Non-HOX Homeobox Genes in Leukemic Hematopoiesis - Full text - MIT Libraries
BM Owens, RG Hawley - Stem Cells, 2002 - stemcells.alphamedpress.org
... levels increase upon differentiation of HEL with hemin, and antisense oligonucleotides
to DLX7 in K562 lead to apoptosis and decreases in c-MYC and GATA1 levels ...
Cited by 32 - Web Search - stemcells.alphamedpress.org - dx.doi.org - ncbi.nlm.nih.gov

A panorama of lineage-specific transcription in hematopoiesis - Full text - MIT Libraries
Y Kluger, Z Lian, X Zhang, PE Newburger, SM … - BioEssays, 2004 - doi.wiley.com
... motif in lineage differentiation as is described above for GATA1 and PU.1 ... examples
of target competition include the alternate formation of Myc–Max complexes ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

acquises de la cellule souche hematopoietique ou d’un precurseur deja commis vers les lignees …
S YNTHESE - MEDECINE/SCIENCES, 2003 - ist.inserm.fr
... Citons aussi la surexpression de la tyrosine kinase LCK, de MYC et d’une forme tronquée ...
Ces leucémies présentent des mutations ponctuelles du gène GATA1. ...
View as HTML - Web Search - erudit.org

Cooperation between the GATA and RUNX factors Serpent and Lozenge during Drosophila hematopoiesis - Full text - MIT Libraries
L Waltzer, G Ferjoux, L Bataille, M Haenlin - The EMBO Journal, 2003 - embojournal.npgjournals.com
... shown in Figure 4D, a flag-tagged version of N-terminally deleted GATA1 expressed
in COS-7 cells was specifically co-immunoprecipitated with myc-tagged RUNX1. ...
Cited by 7 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 6 versions »

Identification of the Spermatogenic Zip Protein Spz 1 as a Putative Protein Phosphatase-1(PP 1) … - Full text - MIT Libraries
C Hrabchak, S Varmuza - J Biol Chem, 2004 - jbc.org
... Goat anti-PP1c , rat anti-GATA1, and horseradish peroxidase-coupled secondary
antibodies ... Chicken antibodies recognizing Myc and HA epitopes were from Aves Labs ...
Cited by 1 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

Targets of the transcriptional repressor oncoprotein Gfi-1 - Full text - MIT Libraries
S Tables, Z Duan, M Horwitz - Proc Natl Acad Sci US A, 2003 - pubmedcentral.nih.gov
... Myc epitope-tagged rat Gfi-1 was synthesized in vitro by using ... GATA1 transcription
factor is indispensable for erythroid and megakaryocyte development (29, 30 ...
Web Search

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... Description GATA1 02 GATA-binding factor 1 GATA1 03 GATA-binding factor 1 GATA1
04 GATA ... 1 NFAT Q6 Nuclear factor of activated T-cells NMYC 01 N-Myc OCT1 02 ...
View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Technical Bulletin
H Protein, H ELISA - sigmaaldrich.com
... area from entire array demonstrates binding of anti-c-Myc-Cy3 to the panel containing
CAMK4. Array not drawn to scale. Cy3/Cy5-biotin BSA CAMK4 GATA1 APSCR1 ...
View as HTML - Web Search - sigmaaldrich.com

Oncogenes and leukemia: history and perspectives
S Gisselbrecht - Med. Sci.(Paris), 2003 - ncbi.nlm.nih.gov
... at the breakpoints of chromosome rearrangements in human malignancies, such as the
MYC gene in ... a key role in hematopoiesis such as C/EBP alpha, GATA1 and AML1. ...
Cited by 1 - Web Search - Get it from MIT Libraries

Therapy-related myeloid leukaemia: A model for leukemogenesis in humans.
RA Larson, MM Le Beau - Chem Biol Interact, 2005 - ncbi.nlm.nih.gov
... control (CCNA2, CCNE2, CDC2), checkpoints (BUB1), or growth (MYC), and loss of ... of
transcription factors involved in early hematopoiesis (TAL1, GATA1, and EKLF ...
Web Search - Get it from MIT Libraries

NF-kappa B transcription factors are involved in normal erythropoiesis - Full text - MIT Libraries
MY Zhang, SC Sun, L Bell, BA Miller - Blood, 1998 - bloodjournal.org
... 10 BFU-E-derived cells, p50, p52, and p65 were able to form complexes, which bound
to B sites in the promoters of both the c-myb and c-myc genes, suggesting ...
Cited by 25 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Characterization of the Myeloid-Specific CDllb Promoter
I HindIIIISma - bloodjournal.org
... Myc Myc Myc ... V, Orkin SH, Constantini F: Erythroid differentiation in chimeric mice
blocked by a targeted mutation in the gene for transcription factor GATA1. ...
Web Search

Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming … - Full text - MIT Libraries
SRTCCBP To, RBMPI Transcription - J. Biol. Chem, 2005 - dx.doi.org
... Negatively Regulates Erythroid Differentiation through Its Interaction with GATA1
Mol. ... Factor {beta}-Mediated Transcriptional Repression of c-myc Is Dependent ...
Cited by 67 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

The‘definitive’(and‘primitive’) guide to zebrafish hematopoiesis - Full text - MIT Libraries
AJ Davidson, LI Zon - Oncogene, 2004 - nature.com
... indication of hematopoietic commitment occurs at the 4-somite stage with the expression
of the erythroid-specific transcription factor gata1 (Detrich et al ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Rapid turnover of GATA-2 via ubiquitin-proteasome protein degradation pathway - Full text - MIT Libraries
N Minegishi, N Suzuki, Y Kawatani, R Shimizu, M … - Genes to Cells, 2005 - blackwell-synergy.com
... was found in Gata1 /y ::Gata2 / double knockout embryos than in Gata1 /y or ... also
been observed in other transcription factors, E2F1, Fos, Jun, c-Myc, and GCN-5 ...
Web Search - ingentaconnect.com - genestocellsonline.org - ncbi.nlm.nih.gov

Essential role of Plzf in maintenance of spermatogonial stem cells - Full text - MIT Libraries
JA Costoya, RM Hobbs, M Barna, G Cattoretti, K … - Nature Genetics, 2004 - nature.com
... Leukemia-Associated protein PLZF is mediated by repression of c-myc expression. ...
development, activates Tpo receptor expression and interacts with GATA1 protein ...
Cited by 5 - Web Search - med.unr.edu - ncbi.nlm.nih.gov - origin.www.nature.com - all 5 versions »