The Transcription Factor SOX 9 Regulates Cell Cycle and Differentiation Genes in Chondrocytic CFK 2 … - Full text - MIT Libraries
DK Panda, D Miao, V Lefebvre, GN Hendy, D Goltzman - J Biol Chem, 2001 - intl.jbc.org
... buffered saline (PBS) and overlaid with 2 µg of SOX9-Myc or SOX9-Myc NLS in 500 ... Human
SOX9 cDNA (12), mouse L-SOX5 (a long product of the Sox5 gene) cDNA (22 ...
Cited by 17 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

T-targets: Clues to understanding the functions of T-box proteins - Full text - MIT Libraries
M Tada, JC Smith - Development Growth and Differentiation, 2001 - dx.doi.org
... 1999), while fgf4 is activated by SOX2, but not by SOX5, by interacting with Oct ...
protein that contains two separate DNA-binding motifs; one is a Myc-like basic ...
Cited by 40 - Web Search - blackwell-synergy.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Basic Helix-loop-helix Protein DEC 1 Promotes Chondrocyte Differentiation at the Early and Terminal … - Full text - MIT Libraries
M Shen, E Yoshida, W Yan, T Kawamoto, K Suardita, … - J Biol Chem, 2002 - jbc.org
... is required for the condensation of prechondrogenic mesenchymal cells, and Sox5
and Sox6 ... decreasing its own transcription, as well as that of c-myc, through the ...
Cited by 14 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov

SOX 7 transcription factor: sequence, chromosomal localisation, expression, transactivation and … - Full text - MIT Libraries
W Takash, J Canizares, N Bonneaud, F Poulat, MG … - Nucleic Acids Research, 2001 - nar.oupjournals.org
... 20°C for 1 min, and then incubated for 30 min with anti-Myc 9E10 (diluted 1 ... within
the same subgroup F (SOX17 and SOX18) and within subgroup D (Sox5, Sox6 and ...
Cited by 26 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Sox 6 regulation of cardiac myocyte development - Full text - MIT Libraries
O Cohen-Barak, Z Yi, N Hagiwara, K Monzen, I … - Nucleic Acids Research, 2003 - nar.oupjournals.org
... conserved between the mouse and human SOX6, and has a 91% identity to L-Sox5 (10). ...
1). A c-Myc epitope tag was attached to the Sox6 bait, and an HA epitope tag ...
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WISP 3-dependent regulation of type II collagen and aggrecan production in chondrocytes - Full text - MIT Libraries
M Sen, YH Cheng, MB Goldring, MK Lotz, DA Carson - Arthritis & Rheumatism, 2004 - doi.wiley.com
... protein with an anti-Myc antibody in the supernatant collected from Myc-tagged WISP3 ...
SOX9, together with L-SOX5 and SOX6, regulates the expression of cartilage ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Interactions between Sox9 and beta-catenin control chondrocyte differentiation - Full text - MIT Libraries
H Akiyama, JP Lyons, Y Mori-Akiyama, X Yang, R … - Genes Dev, 2004 - genesdev.org
... 2000 ) and that L-Sox5 and Sox6 cooperate with Sox9 to activate the Col2a1and ... Cells
are cotransfected with 6x myc-tagged st -catenin and 3xHA-tagged Sox9. ...
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SUMO Represses Transcriptional Activity of the Drosophila SoxNeuro and Human Sox3 Central Nervous … - Full text - MIT Libraries
J Savare, N Bonneaud, F Girard - Mol Biol Cell, 2005 - molbiolcell.org
... cells were transfected with the indicated plasmids and immunostained with either
anti-myc or anti ... Dm SoxN), group C (Hs Sox11 and Dm SoxC), group D (Hs Sox5/6/13 ...
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SOX2 functions to maintain neural progenitor identity - Full text - MIT Libraries
V Graham, J Khudyakov, P Ellis, L Pevny, N Center - Neuron, 2003 - healthsystem.virginia.edu
... Inhibition of SOX2 Activity Results in Lateral fused to a myc epitope-tagged
Engrailed-Repressor (ER) domain, SOX2ER myc , converting SOX2 from a tran- ... myc ...
Cited by 39 - View as HTML - Web Search - bio.unc.edu - ingentaconnect.com - all 6 versions »

Identification of a novel Sry-related gene and its germ cell-specific expression - Full text - MIT Libraries
E Osaki, Y Nishina, J Inazawa, NG Copeland, DJ … - Nucleic Acids Research, 1999 - nar.oupjournals.org
... Some Sox genes, including Sox5 and Sox17, are differentially expressed during ... generated
by inserting a synthesized oligonucleotide containing a myc tag sequence ...
Cited by 13 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Smad-Dependent Recruitment of a Histone Deacetylase/Sin3A Complex Modulates the Bone Morphogenetic … - Full text - MIT Libraries
DW Kim, AB Lassar - Mol Cell Biol, 2003 - pubmedcentral.nih.gov
... 3, 4, 37, 53, 60) and other prochondrogenic genes such as L-Sox5 and Sox6 ... Smad3 can
support TGF-β-dependent transcriptional repression of the c-myc promoter (7 ...
Cited by 5 - Web Search - dx.doi.org - mcb.asm.org - ncbi.nlm.nih.gov

Molecular genetics of pineal region neoplasms
MD Taylor, TG Mainprize, JA Squire, JT Rutka - Journal of Neuro-Oncology, 2001 - springerlink.com
... They also found high levels of expres- sion of C-myc in one case of pineocytoma
simi- lar ... They found three genes encoded within the SROA: KRAS2, JAW1 and SOX5. ...
Cited by 2 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Pathogenesis of testicular germ cell tumours - Full text - MIT Libraries
LH Looijenga, JW Oosterhuis - Rev Reprod, 1999 - ror.reproduction-online.org
... Three known genes are located in the SROA: SOX5, JAW1 and K-RAS (Fig. ... Overexpression
of c-MYC has been de- tected in < 10% of nonseminomas (Misaki et al., 1989 ...
Cited by 48 - Web Search - dx.doi.org - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon- … - Full text - MIT Libraries
M Osaki, L Tan, BK Choy, Y Yoshida, KS Cheah, PE … - Biochem. J, 2003 - biochemj.org
... increased Sox5 and Sox6 mRNA levels in the presence but not in the absence
of IFN-γ. ... However, a consensus GAS element in the c-myc ...
Cited by 15 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Sox genes and cancer - Full text - MIT Libraries
C Dong, D Wilhelm, P Koopman, F Alert - Cytogenetic and Genome Research, 2004 - content.karger.com
... v-ras and v-mos oncogenes and by co-transfection with c-myc and polyoma ... Stoop H,
Millan J, Oosterhuis J, Looijenga L: Coamplification of DAD-R, SOX5, and EKI1 ...
Cited by 1 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

Restricted 12p amplification and RAS mutation in human germ cell tumors of the adult testis - Full text - MIT Libraries
H Roelofs, MC Mostert, K Pompe, G Zafarana, M van … - Am J Pathol, 2000 - ajp.amjpathol.org
... 42– 45 We showed that the shortest region of overlap of amplification (SROA) is
1.7 Mbases, contain- ing three known genes, ie, SOX5, JAW1, and K-RAS. 45 It ...
Cited by 20 - Web Search - ajp.amjpathol.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Constitutive E2F1 Overexpression Delays Endochondral Bone Formation by Inhibiting Chondrocyte … - Full text - MIT Libraries
B Scheijen, M Bronk, T van der Meer, R Bernards - Mol Cell Biol, 2003 - mcb.asm.org
... the chondrocyte differentiation pathway and is required for expression of Sox5 and
Sox6. ... p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression ...
Cited by 2 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... 2 MINI20 B Muscle initiator sequence-20 MUSCLE INI B Muscle initiator NF1 Q6 Nuclear
factor 1 NFAT Q6 Nuclear factor of activated T-cells NMYC 01 N-Myc OCT1 02 ...
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The testicular germ cell tumour genome - Full text - MIT Libraries
RI SKOTHEIM, RA LOTHE - Apmis, 2003 - ingentaconnect.com
... MYBL2 B-MYB v-myb myeloblastosis viral oncogene homolog 20q13.12 67 (avian)-like
2 MYCL1 L-MYC v-myc myelocytomatosis viral oncogene homolog 1, 1p34.2 67 ...
Cited by 14 - Web Search - ingentaconnect.com - folk.uio.no - ncbi.nlm.nih.gov

Divergent Regulation of the Growth-promoting Gene IEX-1 by the p 53 Tumor Suppressor and Sp 1 - Full text - MIT Libraries
HJ Im, MR Pittelkow, R Kumar - J Biol Chem, 2002 - jbc.org
... growth factor stimulation include nuclear proteins (eg c-Fos, c-Jun, c-Myc, zinc
finger ... TCT TCA CCA CCA ATC CTG GCA GAG-3'. Other Sox cDNAs (Sox5, Sox6, and ...
Cited by 10 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Ovary: Germ cell tumors
O Note, E Carcinoma, MGC Tumour - caroll.vjf.cnrs.fr
... Several genes including KRAS2, JAW1 and SOX5 have been suggested as the ... N-myc gene
amplification and neuron specific enolase production in immature teratomas. ...
Cached - Web Search

Genomic Mechanisms of p210
S Ray, Y Lu, SH Kaufmann, WC Gustafson, JE Karp, I … - bioinfo.utmb.edu
... of p21 ras , either by administration of antisense oligonucleotides or microinjection
of blocking antibodies, prevents expression of the c-myc proto-oncogene ...
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Genomic Mechanisms of p210 BCR-ABL Signaling - Full text - MIT Libraries
S Ray, Y Lu, SH Kaufmann, WC Gustafson, JE Karp, I … - J. Biol. Chem, 2004 - jbc.org
... microinjection of blocking antibodies, prevents expression of the c-myc proto-oncogene ...
C-binding enigma; HOX, homeobox; MYB, c-myb oncogene; SOX5, Sry-related ...
Cited by 2 - Web Search - dx.doi.org - jbc.org

Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted … - Full text - MIT Libraries
X Ma, T Husain, H Peng, S Lin, O Mironenko, N Maun … - Blood, 2002 - bloodjournal.org
... Sox4 Important for very early B-cell differentiation 2.1 1.1 2.7 0.26 Sox5 SRY-box
containing gene 5 — 3.1 0.22 Tal1 T-cell acute lymphocytic leukemia 1 ...
Cited by 6 - Web Search - info.med.yale.edu - dx.doi.org - ncbi.nlm.nih.gov - all 8 versions »

Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel … - Full text - MIT Libraries
V Bourdon, F Naef, PH Rao, V Reuter, SC Mok, GJ … - Cancer Res, 2002 - cancerres.aacrjournals.org
... These included SOX5, LRMP (JAW1), KRAS2, FGF6, TEL, CDKN1B (KIP1), PTHLH, LDHB ... PH,
Murty VV, Louie DC, Chaganti RS Nonsyntenic amplification of MYC with CDK4 ...
Cited by 10 - Web Search - ws1.izbi.uni-leipzig.de - cancerres.aacrjournals.org

Effectors of mammalian telomere dysfunction: a comparative transcriptome analysis using mouse models - Full text - MIT Libraries
S Franco, A Canela, P Klatt, MA Blasco - Carcinogenesis, 2005 - carcin.oxfordjournals.org
... functional classes: (i) the Sry/Sox family of transcription factors (Sry, Sox5,
Sox9 and ... AHR/ARNT), upstream stimulating factor (USF), as well as n-Myc and Max ...
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TUMEURS DU TESTICULE
AT GERMINALES - urofrance.org
... Au sein de la région amplifiée 12p11.2-p12.1 siègent plusieurs gènes candidats tels
que K-Ras, JAW 1, SOX5 et PTLH ... c-kit, gene SCF, c-MOS, c-myc, N-myc ...
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The T-box transcription factor Brachyury mediates cartilage development in mesenchymal stem cell … - Full text - MIT Libraries
A Hoffmann, S Czichos, C Kaps, D Bachner, H Mayer, … - J Cell Sci, 2002 - jcs.biologists.org
Summary of this Article. Figures Only for this Article. PDF Version of this Article.
Email this article to a friend. Similar articles found in: JCS Online PubMed ...
Cited by 13 - Web Search - jcs.biologists.org - ncbi.nlm.nih.gov

Genetics and biology of adult human male germ cell tumors - Full text - MIT Libraries
RSK Chaganti, J Houldsworth - Cancer Res, 2000 - cancerres.aacrjournals.org
... 3 ). Although the RASK2, SOX5, and JAW1 genes have been shown to be contained within
this region, their functional roles in GCT development remain to be ...
Cited by 66 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

Inhibition of chondrocyte differentiation in vitro by constitutive and inducible overexpression of … - Full text - MIT Libraries
DP Thomas, A Sunters, A Gentry, AE Grigoriadis - J. Cell Sci, 2000 - jcs.biologists.org
Page 1. INTRODUCTION The control of proliferation and differentiation of
chondrogenic cells is central to the coordinated development ...
Cited by 16 - Web Search - jcs.biologists.org - ncbi.nlm.nih.gov

Transcriptionally Targeted Adenovirus Vectors
H Sadeghi, MM Hitt - Current Gene Therapy, 2005 - ingentaconnect.com
... 2). E-boxes located at -165 to-160 and +44 to +49 relative to the transcriptional
start site are recognized by Myc and Mad factors, binding of which induces or ...
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Germinal tumor invasion and the role of the testicular stroma
A Diez-Torre, U Silvan, O DE WEVER, E Bruyneel, M … - Int. J. Dev. Biol, 2004 - ijdb.ehu.es
Page 1. Germinal tumor invasion and the role of the testicular stroma
ALEJANDRO DÍEZ-TORRE 1 , UNAI SILVÁN 1 , OLIVIER DE WEVER ...
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A Bayesian Insertion/Deletion Algorithm for Distant Protein Motif Searching via Entropy Filtering - Full text - MIT Libraries
J Xie, KC Li, M Bina - Journal of the American Statistical Association, 2004 - ingentaconnect.com
Page 1. A Bayesian Insertion/Deletion Algorithm for Distant Protein Motif Searching
via Entropy Filtering Jun X IE , Ker-Chau L I , and Minou B INA ...
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