SRY Interacts with and Negatively Regulates Androgen Receptor Transcriptional Activity - Full text - MIT Libraries
X Yuan, ML Lu, T Li, SP Balk - J Biol Chem, 2001 - jbc.org
... on SDS-polyacrylamide gel electrophoresis, the upper half of the gel was immunoblotted
for AR, and the lower half was immunoblotted for the SRY Myc epitope tag ...
Cited by 13 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

SOX 9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors - Full text - MIT Libraries
R SEKIDO, I BAR, V NARVAEZ, G PENNY, R LOVELLBADGE - Developmental Biology, 2004 - ncbi.nlm.nih.gov
... of a stable reporter, human placental alkaline phosphatase (hPLAP), while the second
gives expression of a functional Myc-epitope tagged SRY protein (SRYMYC). ...
Cited by 7 - Web Search

Structural organization and chromosomal localization of the mouse tesk1 (testis-specific protein … - Full text - MIT Libraries
J Toshima, K Nakagawara, M Mori, T Noda, K Mizuno - Gene, 1998 - ingentaconnect.com
... region is devoid of a TATA box, but does contain several potential binding sites
for transcription factors, including Sp1, AP-1, c-Myc, SRY and CREM (cyclic AMP ...
Cited by 4 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

From SRY to SOX9: Mammalian Testis Differentiation - Full text - MIT Libraries
Y Kanai, R Hiramatsu, S Matoba, T Kidokoro - Journal of Biochemistry, 2005 - jb.oxfordjournals.org
... Sekido et al. (Ref. 16 ) generated two types of transgenic lines containing most
of the 14.6-kb murine Sry genomic sequence (Sry-Myc and Sry-hPLAP in Fig. ...
Web Search - jb.oxfordjournals.org

Identification of a novel Sry-related gene and its germ cell-specific expression - Full text - MIT Libraries
E Osaki, Y Nishina, J Inazawa, NG Copeland, DJ … - Nucleic Acids Research, 1999 - nar.oupjournals.org
... thereafter, regulation of male development by expression of Sry was clearly ... generated
by inserting a synthesized oligonucleotide containing a myc tag sequence ...
Cited by 13 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Interleukin-2 overexpresses c-myc and down-regulates cytochrome P-450 in rat hepatocytes - Full text - MIT Libraries
M Tinel, J Elkahwaji, MA Robin, N Fardel, V … - J Pharmacol Exp Ther, 1999 - jpet.aspetjournals.org
... of JAK3: Possible involvement in signal transduction for c-myc induction and ... MA
(1998) IRE-ABP (insulin response element-A binding protein), an SRY-like protein ...
Cited by 13 - Web Search - jpet.aspetjournals.org - ncbi.nlm.nih.gov

RNA binding domain of HDV antigen is homologous to the HMG box of SRY - Full text - MIT Libraries
S Veretnik, M Gribskov - Archives of Virology, 1999 - springerlink.com
... It has been shown that the HMG box of the SRY protein is involved in specific ... In
fact, the expression of the proto-oncogene c-myc is a hallmark of chronic HDV ...
Cited by 1 - Web Search - bio.purdue.edu - ncbi.nlm.nih.gov

Identification of genes that are regulated transcriptionally by Myc in childhood tumors
EA Raetz, MKH Kim, P Moos, M Carlson, C Bruggers, … - Cancer, 2003 - doi.wiley.com
... 71 Expression ratio a C-Myc target? Neuroblastoma cell lines Medulloblastoma cell
lines ... ELF3 166096 AF017307 1.82 1.66 1.47 2.96 1.60 2.14 Yes SOX8 SRY
Cited by 10 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Sex reversal by loss of the C–terminal transactivation domain of human SOX 9
P Suedbeck, ML Schmitz, PA Baeuerle, G Scherer - Nature Genetics, 1996 - nature.com
... Clark, HM et al.Mutations in the coding region of c-myc in AIDS-associated and other
aggressive lymphomas. ... SRY, like HMG1, recognizes sharp angles in DNA. ...
Cited by 87 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Muscle Differentiation Is Antagonized by SOX 15, a New Member of the SOX Protein Family - Full text - MIT Libraries
F Beranger, C Mejean, B Moniot, P Berta, M … - J Biol Chem, 2000 - jbc.org
... nuclear extracts were prepared from COS 7 cells transfected with Myc-tagged sox15 ...
probes corresponding to two SOX binding site consensus sequences (SRY and T ...
Cited by 12 - Web Search - jbc.org - ncbi.nlm.nih.gov

High expression of the HMG box factor Sox-13 in arterial walls during embryonic development - Full text - MIT Libraries
J Roose, W Korver, E Oving, A Wilson, G Wagenaar, … - J. Biol. Chem, 2004 - nar.oupjournals.org
... the X chromosome and appears to be the closest relative of Sry, together arguing ...
was constructed by inserting a HindIII-BamHI fragment containing a MYC-tag and ...
Cited by 17 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

CATALOGS OF GENES OF INTEREST IN ENDOCRINOLOGY AND REPRODUCTION FROM METATHERIAN & PROTOTHERIAN …
M MAMMALS - il-st-acad-sci.org
... X, SRY, sex determining region Y. WALLAROO (Macropus robustus): 5 loci. Chromosome,
Symbol, Name. 4, MYC, avian myelocytomatosis viral (v-myc) oncogene homolog. ...
Cached - Web Search

Deletion of Y-chromosome specific genes in human prostate cancer
G Perinchery, M Sasaki, A Angan, V Kumar, P … - J Urol, 2000 - jurology.com
... In the present study, we examined six different Y-chromosome-specific genes (SRY,
ZFY, BPY1 ... 12 and Y, and loss of chromosome 8 and extra copies of c-myc gene in ...
Cited by 10 - Web Search - jurology.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

One tissue, two fates: molecular genetic events that underlie testis versus ovary development - Full text - MIT Libraries
J Brennan, B Capel - Nature Reviews Genetics, 2004 - nature.com
... This paper, which tracked the expression of the SRY protein through a MYC tag and
promoter activation through alkaline phosphatase, showed that SRY is ...
Cited by 18 - Web Search - cellbio.duke.edu - note.cellbio.duke.edu - ncbi.nlm.nih.gov - all 5 versions »

UTP Induces Osteopontin Expression through a Coordinate Action of NF {kappa} B, Activator Protein-1, … - Full text - MIT Libraries
MA Renault, S Jalvy, M Potier, I Belloc, E Genot, … - J Biol Chem, 2005 - jbc.org
... AP-4/Ebox (probe 2) (–1788 to–1759); AP-4 (–1790 to–1777); Sry (–1778 to ... USF-2 (kindly
provided by Dr. B. Viollet (31)), anti-p65, anti-c-Myc, and anti ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Cpf1 protein induced bending of yeast centromere DNA element I - Full text - MIT Libraries
RK Niedenthal, M Sen-Gupta, A Wilmen, JH Hegemann - Nucleic Acids Res, 1993 - pubmedcentral.nih.gov
... SRY, like HMG1, recognizes sharp angles in DNA. ... The human myc gene family:
structure and activity of L-myc and an L-myc pseudogene. ...
Cited by 15 - Web Search - nar.oupjournals.org - ncbi.nlm.nih.gov

In simple synthetic promoters YY 1-induced DNA bending is important in transcription activation and … - Full text - MIT Libraries
J Kim, DJ Shapiro - Nucleic Acids Research, 1996 - nar.oupjournals.org
... transcription regulators are LEF1 ( 27 , 28 ), HMG I/Y ( 29 ), SRY ( 30 , 31 ... YY1
activates transcription of the c- myc promoter ( 36 ), and the promoters of ...
Cited by 23 - Web Search - nar.oupjournals.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Untitled
dx.doi.org
... M., Oosterwegel, M., van Norren, K. & Clevers, H. Sox-4, an Sry-like HMG ... Cerni, C.,
Luscher-Firzlaff, JM & Luscher, B. YY1 can inhibit c-Myc function through a ...
Cited by 83 - nature.com - nature.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Differential splicing creates a diversity of transcripts from a neurospecific developmentally … - Full text - MIT Libraries
VL Buchman, NN Ninkina, YD Bogdanov, AL Bortvin, … - Nucleic Acids Res, 1992 - pubmedcentral.nih.gov
... sry h-1, a new Drosophila melanogaster multifingered protein gene showing ... Novel zinc
finger gene implicated as myc collaborator by retrovirally accelerated ...
Cited by 14 - Web Search - nar.oupjournals.org - ncbi.nlm.nih.gov

A Drosophila nuclear localisation signal included in an 18 amino acid fragment from the serendipity …
S Noselli, A Vincent - FEBS Lett, 1991 - ncbi.nlm.nih.gov
... amino acids, with homology to the SV40 large T and c-myc nuclear localisation ... fusion
proteins, containing (or not) an 18 residue segment of sry delta including ...
Cited by 2 - Web Search - Get it from MIT Libraries

Research Letter TSPY Detection in Blood, Buccal, and Urine Cells of Patients With 45, X Karyotype - Full text - MIT Libraries
X tionsforpatientswithUTSstigmataand45 - American Journal of Medical Genetics, 2004 - doi.wiley.com
... There were no positive results for SRY and DAZ in blood samples. ... chain reaction compared
with dot blotting for determination of N-myc gene amplification in ...
Web Search

Microphthalmia-Associated Transcription Factor(MITF) is Required but is Not Sufficient to Induce the … - Full text - MIT Libraries
C Gaggioli, R Busca, P Abbe, JP Ortonne, R … - Pigment Cell Research, 2003 - ingentaconnect.com
... SOX10, a sex-determining(SRY) related tran- scription factor has been shown to
stimulate DCT ... Both sequences were tagged at the C-terminal with the c-myc tag. ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The Transcription Factor SOX 9 Regulates Cell Cycle and Differentiation Genes in Chondrocytic CFK 2 … - Full text - MIT Libraries
DK Panda, D Miao, V Lefebvre, GN Hendy, D Goltzman - J Biol Chem, 2001 - intl.jbc.org
... heart and is a relative of the mammalian Y-linked sex-determining gene, SRY. ... A SOX9
deletion mutant (SOX9-Myc NLS) lacking the first 176 amino acids (within ...
Cited by 17 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Molecular evolution of the plant R regulatory gene family - Full text - MIT Libraries
MD Purugganan, SR Wessler - Genetics, 1994 - genetics.org
... ily encode myc-like proteins which contain a basic helix-loop-helix (bHLH) motif
found in other eukary- otic transcriptional activators such as Max and MyoDl ...
Cited by 27 - Web Search - plantbio.uga.edu - botany.uga.edu - ncbi.nlm.nih.gov - all 5 versions »

Screens for piwi Suppressors in Drosophila Identify Dosage-Dependent Regulators of Germline Stem … - Full text - MIT Libraries
TK Smulders-Srinivasan, H Lin - Genetics, 2003 - genetics.org
... Ovarioles in C, C' and D, D' show no significant difference in the Myc-Piwi
expression, implying that sry- does not regulate piwi expression. ...
Cited by 1 - Web Search - linweb.cellbio.duke.edu - genetics.org - ncbi.nlm.nih.gov - all 5 versions »

Supplementary data Table I.
T NP, SV VP, SV VP - emboreports.npgjournals.com
... SRY. Sudbeck and Scherer (1997). PRRRK. SRY. Sudbeck and Scherer (1997).
KRPMNAFMVWAQAARRK. SOX9. ... Dang and Lee (1989). PPQKKIKS. N-myc. Dang and Lee (1989). ...
Web Search

Renal Tubule-specific Transcription and Chromosomal Localization of Rat Thiazide-sensitive Na-Cl … - Full text - MIT Libraries
Y Taniyama, K Sato, A Sugawara, A Uruno, Y Ikeda, … - J Biol Chem, 2001 - jbc.org
... indicate the following putative cis-acting elements: TATA, TATA box; SRY, SRY biding
site ... CRE, cAMP-responsive element; AP-2, AP-2 binding site; c-MYC, c-MYC ...
Cited by 6 - Web Search - jbc.org - ncbi.nlm.nih.gov

Genetics for the paediatric surgeon
AD Lander, AD Lander - Surgery, 2004 - extenza-eps.com
... The SOX9 product is related to SRY and, when mutated, may block its action. ... contain
multiple copies of a gene, MYCN, a member of the myc oncogene family. ...
Web Search - extenza-eps.com - dx.doi.org

Cbfa1, an essential transcription factor for bone formation, is expressed in testis from the same … - Full text - MIT Libraries
S Ogawa, H Harada, M Fujiwara, S Tagashira, T … - DNA Res, 2000 - dna-res.kazusa.or.jp
... 3). 12 GATA-1, SRY, AP-1 and c-Myc are expressed in testicular germ cells and are
thought to function in transcriptionalregulation during spermatogenesis. ...
Cited by 8 - View as HTML - Web Search - dna-res.kazusa.or.jp - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cooperative Transcriptional Activation by Serum Response Factor and the High Mobility Group Protein … - Full text - MIT Libraries
JA Spencer, MH Baron, EN Olson - J Biol Chem, 1999 - jbc.org
... which includes the lymphoid enhancer-binding factor, LEF-1, the sex-determining
factor, SRY, the related ... Myc-SSRP1 expression plasmid was provided by M. Baron. ...
Cited by 17 - Web Search - jbc.org - ncbi.nlm.nih.gov

Dihydrotestosterone stimulates branching morphogenesis, cell proliferation, and programmed cell … - Full text - MIT Libraries
BM Levesque, RJ Vosatka, HC Nielsen - Pediatr Res, 2000 - pedresearch.org
... DNA shows amplified bands at 147 bases (Sry 1 and 3), 404 bases (Sry 2 and 4 ... the
expression of a variety of cell cycle–regulating genes, including c-myc and h ...
Cited by 7 - Web Search - pedresearch.org - ncbi.nlm.nih.gov

Interleukin-6 from intrahepatic cells of bone marrow origin is required for normal murine liver … - Full text - MIT Libraries
X Aldeguer, F Debonera, A Shaked, AM Krasinkas, AE … - Hepatology, 2002 - dx.doi.org
... 6 disrupted allele, whereas males receiving female marrow demonstrated no SRY or
IL ... of transcription 3 (STAT3) activation, and depressed AP-1, Myc, and cyclin ...
Cited by 18 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Appendix: Finding nuclear localization signals
M Cokol, R Nair, B Rost - cubic.bioc.columbia.edu
... KRPMNAFIVWSRDQRRK SRY Sudbeck and Scherer, 1997. PRRRK SRY Sudbeck and Scherer,
1997. ... PLLKKIKQ c-myb Dang and Lee, 1989. PPQKKIKS N-myc Dang and Lee, 1989. ...
Cached - Web Search

Original Research Article Microphthalmia-Associated Transcription Factor (MITF) is Required but is … - Full text - MIT Libraries
C Gaggioli, R Busca, P Abbe, JP Ortonne, R … - Pigment Cell Research, 2003 - blackwell-synergy.com
... SOX10, a sex-determining (SRY) related transcription factor has been shown to stimulate
DCT ... Both sequences were tagged at the C-terminal with the c-myc tag. ...
Web Search

Translocation breakpoints in three patients with campomelic dysplasia and autosomal sex reversal map … - Full text - MIT Libraries
J Wirth, T Wagner, J Meyer, RA Pfeiffer, HU Tietze … - Hum. Genet, 1996 - springerlink.com
... dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene ...
Burkitt’s lymphoma cells fall within a region 140 kilobases distal from c-myc. ...
Cited by 38 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Genome and Hormones: Gender Differences in Physiology - Full text - MIT Libraries
H Ostrer - J Appl Physiol, 2001 - jap.physiology.org
... Dubin, RA, and Ostrer H. Sry is a transcriptional activator. ... Multiple androgen response
elements and a Myc consensus site in the androgen receptor (AR) coding ...
Cited by 2 - Web Search - jap.physiology.org

Conservation of read-through transcription of the Drosophila serendipity genes during evolution is … - Full text - MIT Libraries
S Ibnsouda, P Ferrer, A Vincent - Mol Gen Genet, 1998 - springerlink.com
... in Drosophila) density of functionally independent transcription units at the
janus/sry/rp49 gene ... end formation of a DNA fragment from the human c-myc 3¢-end ...
Cited by 2 - Web Search - springerlink.com - ncbi.nlm.nih.gov

SOX 7 transcription factor: sequence, chromosomal localisation, expression, transactivation and … - Full text - MIT Libraries
W Takash, J Canizares, N Bonneaud, F Poulat, MG … - Nucleic Acids Research, 2001 - nar.oupjournals.org
... been given for HMG containing proteins sharing >60% homology to SRY in the ... deleted
constructs, shown in Figure 5, were inserted into the Myc-tagged modified ...
Cited by 26 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

A Direct{beta}-Catenin-independent Interaction between Androgen Receptor and T Cell Factor 4 - Full text - MIT Libraries
AL Amir, M Barua, NC McKnight, S Cheng, X Yuan, SP … - J Biol Chem, 2003 - jbc.org
... Primers flanking Tcf4 binding element 1 in the c-myc promoter (CCTTTGATT at ... data
demonstrating a protein-protein interaction between AR and SRY that was ...
Cited by 9 - Web Search - jbc.org - ncbi.nlm.nih.gov

Differential roles for SOX 15 and SOX 2 in transcriptional control in mouse embroyonic stem cells - Full text - MIT Libraries
M Maruyama, T Ichisaka, M Nakagawa, S Yamanaka - Journal of Biological Chemistry, 2005 - jbc.org
... arise from a group of genes related to the mammalian testis-determining factor Sry
(15, 16). ... oct3/4) were recombined with pCAG-IP-HA-gw and pCAG-IP-Myc-gw by ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Molecular Genetic Analysis of Placental Site Trophoblastic Tumors and Epithelioid Trophoblastic … - Full text - MIT Libraries
RJ Oldt, RJ Kurman, IM Shih - American Journal of Pathology, 2002 - ajp.amjpathol.org
... organization, and promoter sequence of the human sex-determining region Y (SRY)
gene, using ... Mok SC, Genest DR, Szigetvari I, Cseh I, Berkowitz RS: c-myc, c-erbB ...
Cited by 2 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Intrinsically bent DNA in a eukaryotic transcription factor recognition sequence potentiates … - Full text - MIT Libraries
J Kim, S Klooster, DJ Shapiro - J Biol Chem, 1995 - jbc.org
... factor (LEF-1)(18) , YY1(19) , and the mammalian sex determining factor SRY(18 ... have
also been reported for homo- and heterodimeric complexes of c-Myc and Max (28 ...
Cited by 22 - Web Search - jbc.org - ncbi.nlm.nih.gov

Position effect in human genetic disease - Full text - MIT Libraries
D Kleinjan, V van Heyningen - Human Molecular Genetics, 1998 - dx.doi.org
... For instance, in Burkitt's lymphoma a translocation places the c-MYC gene under
the control of an immunoglobulin ... SRY, Sex reversal, 3 kb, 5[prime]/3[prime], 54,55 ...
Cited by 118 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Murine protein kinase CK2: gene and oncogene
X Xu, E Landesman-Bollag, PL Channavajhala, DC … - Mol Cell Biochem, 1999 - kluweronline.com
... ad.jp/ SITITFSEARCH.html) and other potential transcriptional factor binding sites
were identified, including sites for SRY, CRE-BP, AP-1, p300, Myc, and C ...
Cited by 14 - Web Search - springerlink.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Mint Represses Transactivation of the Type II Collagen Gene Enhancer through Interaction with {alpha … - Full text - MIT Libraries
X Yang, J Li, H Qin, H Yang, J Li, P Zhou, Y Liang … - J. Biol. Chem, 2005 - jbc.org
... Col2a1 in chondrocytes (5–9). Several transcription factors, including SOX9
(Sry-type high ... Expression vectors pCMV-Myc-MINTF6, pCMV-FLAG-CRYBP1-C, and pCMV-HA ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Cisplatin resistance and transcription factors.
T Torigoe, H Izumi, H Ishiguchi, Y Yoshida, M … - Curr. Med. Chem.-Anti-Cancer Agents, 2005 - ingentaconnect.com
... cisplatin: p53/p73, c-Myc, YB-1, CTF2, ATF4, ZNF143 and mtTFA. ... mtTFA*, UBF TBP,
YB-1*, ZNF143* HMG1/2, SRY, SSRP1 XPE, XPA, MutSα, MSH2 Histone H1 ...
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Molecular diagnosis of sex chromosome aneuploidy using quantitative PCR - Full text - MIT Libraries
GL Mutter, RJ Pomponio - Nucleic Acids Res, 1991 - pubmedcentral.nih.gov
... [ Free Full text in PMC]; Schreiber G, Dubeau L. C-myc proto-oncogene ... P, Lovell-Badge
R. Male development of chromosomally female mice transgenic for Sry. ...
Cited by 6 - Web Search - nar.oupjournals.org - ncbi.nlm.nih.gov

Molecular Pathways of Regeneration and Repair after Liver Transplantation - Full text - MIT Libraries
KM Olthoff - World Journal of Surgery, 2002 - springerlink.com
... Up-regulation of c-jun and c-myc was seen in both the minimally ischemic and ... 9. a.
DNA PCR demonstrating the presence of the SRY locus of the Y chromosome in ...
Cited by 13 - Web Search - ncbi.nlm.nih.gov

Inconclusive presence of adenovirus sequences in human leukemias and lymphomas - Full text - MIT Libraries
… , J FORTEZA, C PARADA, R SANCHEZ-PRIETO, SRY CAJAL - ONCOLOGY REPORTS, 2002 - 147.52.72.117
... A, Sagara M, Sugiyama F, Horiguchi H, Kamma H, Hatae T, Ogata T, Yagami K and Murakami
K: Neuroecto- dermal tumors expressing c-, L-, and N-myc in transgenic ...
Cited by 1 - View as HTML - Web Search - virology.med.uoc.gr

In Silico Identification of Regulatory Elements of GRIN 1 Genes
MK Mejia-Guerra, LR Lareo - Omics A Journal of Integrative Biology, 2005 - dx.doi.org
... was far from the site where the transcription began, a binding motif for Sry-delta
since it ... s GRIN1 they are for D1, E12, SRF, Sp1, MTB-Zf, ROR , Myc-Max, Nkx-2 ...
Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries