SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase - Full text - MIT Libraries
BL Bennett, DT Sasaki, BW Murray, EC O'Leary, ST … - Blood, 2005 - dx.doi.org
... and JM Redondo c-Jun N-terminal Kinase (JNK) Positively Regulates NFATc2
Transactivation through Phosphorylation within the N-terminal Regulatory Domain ...
Cited by 410 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

[CITATION] Induction of T Helper Type 2 Immunity by a Point Mutation in the LAT Adaptor - Full text - MIT Libraries
E Aguado, S Richelme, S Nunez-Cruz, A Miazek, AM … - Immunity, 1998
... Xiao-Jun Guo, 1* Danielle Sainty, 2 Hai-Tao He, 1 Bernard Malissen, 1 ... 4 C), the values
of which exceeded those reported for mice deprived of NFATc2 and NFATc3 ...
Cited by 55 - Web Search - biology.ccsu.edu - img.cas.cz - dx.doi.org - all 7 versions »

Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and … - Full text - MIT Libraries
A Behrens, K Sabapathy, I Graef, M Cleary, GR … - J. Biol. Chem, 2005 - dx.doi.org
... and JM Redondo c-Jun N-terminal Kinase (JNK) Positively Regulates NFATc2
Transactivation through Phosphorylation within the N-terminal Regulatory Domain ...
Cited by 30 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

c-Jun N-terminal Kinase (JNK) Positively Regulates NFATc2 Transactivation through Phosphorylation … - Full text - MIT Libraries
I Ortega-Perez, E Cano, F Were, M Villar, J … - J. Biol. Chem, 2005 - jbc.org
... c-Jun N-terminal Kinase (JNK) Positively Regulates NFATc2 Transactivation through
Phosphorylation within the N-terminal Regulatory Domain * {boxs}. ...
Web Search - jbc.org - ncbi.nlm.nih.gov

… expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun - Full text - MIT Libraries
F Macian, C Garcia-Rodriguez, A Rao - The EMBO Journal, 2000 - embojournal.npgjournals.com
... formed by the nuclear factor of activated T cells (NFAT) and Fos–Jun (AP-1 ... factors
contains five distinct NFAT proteins: NFAT1 (NFATp or NFATc2), NFAT2 (NFATc ...
Cited by 73 - Web Search - nature.com - emboj.org - smbs.buffalo.edu - all 8 versions »

c-Jun N-terminal kinases(JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT … - Full text - MIT Libraries
Q Liang, OF Bueno, BJ Wilkins, CY Kuan, Y Xia, JD … - The EMBO Journal, 2003 - embojournal.npgjournals.com
... extracellular signal-regulated protein kinases (ERKs), the c-Jun N-terminal ... activated
resulting in the direct dephosphorylation of NFATc1, NFATc2, NFATc3 and ...
Cited by 12 - Web Search - nature.com - emboj.org - medicine.uiowa.edu - all 7 versions »

NFATc2 (M-20): sc-1151
I Santa Cruz Biotechnology - genetimes.com.cn
... factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. ... T cells
(1-5). Members of the family include NFATc1 (NFATc), NFATc2 (NFATp), NFATn ...
View as HTML - Web Search

Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation - Full text - MIT Libraries
S Diehl, CW Chow, L Weiss, A Palmetshofer, T … - J. Exp. Med, 2002 - intl.jem.org
... NFATc1 and NFATc2 together control both T and B cell activation and differentiation. ...
c-Jun NH(2)-terminal kinase inhibits targeting of the protein phosphatase ...
Cited by 18 - Web Search - dx.doi.org - jem.org - ncbi.nlm.nih.gov - all 5 versions »

Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast … - Full text - MIT Libraries
F Ikeda, R Nishimura, T Matsubara, S Tanaka, J … - J Clin Invest, 2004 - jci.org
... Blockade of c-Jun signaling also markedly inhibited soluble RANKL-induced osteoclast ...
of nuclear factor of activated T cells 1 (NFAT1) (NFATc2/NFATp) or NFAT2 ...
Cited by 7 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

RANKing c-Jun in osteoclast development - Full text - MIT Libraries
SL Teitelbaum, M Similarly - J. Clin. Invest, 2004 - jci.org
... JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and
-independent mechanisms. ... Regulation of the Murine Nfatc1 Gene by NFATc2. ...
Cited by 4 - Web Search - pubmedcentral.nih.gov - tufts.edu - ncbi.nlm.nih.gov - all 5 versions »

A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1 - Full text - MIT Libraries
H Okamura, C Garcia-Rodriguez, H Martinson, J Qin, … - Mol. Cell. Biol, 2004 - pubmedcentral.nih.gov
... is composed of four calcium-regulated members, NFAT1 (also known as NFATc2 or NFATp ...
synthase kinase 3 (GSK3), casein kinase 1 (CK1), p38, and c-Jun N-terminal ...
Cited by 8 - Web Search - dx.doi.org - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

… the Orientation of Fos-Jun Binding and the Transcriptional Cooperativity of Fos-Jun-NFAT 1 Complexes - Full text - MIT Libraries
VR Ramirez-Carrozzi, TK Kerppola - J Biol Chem, 2001 - jbc.org
... 23, 24). The interaction between Fos-Jun and NFAT1 (NFATp, NFATc2) has
been characterized in greatest detail. Cooperative binding ...
Cited by 3 - Web Search - jbc.org - ncbi.nlm.nih.gov

Involvement of c-Jun N-terminal kinase activities in skeletal muscle differentiation
A Khurana, CS Dey - Journal of Muscle Research and Cell Motility, 2004 - springerlink.com
... A, Teixeira LK, Werneck MB, Barcinski MA and Viola JP (2002) NFATC2 transcription
factor ... Zenz R, Wagner EF and Zatloukal, K (1999) Functions of c-Jun in liver ...
Web Search - ingentaconnect.com - ijp-online.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

NFAT expression in human osteoclasts - Full text - MIT Libraries
CJ Day, MS Kim, CM Lopez, GC Nicholson, NA … - Journal of Cellular Biochemistry, 2005 - doi.wiley.com
... NFATc1 expression during osteoclast forma- tion has been linked to c-fos
[Matsuo et al., 2004], NFATc2 and c-jun [Ikeda et al., 2004]. ...
Web Search - ncbi.nlm.nih.gov

[CITATION] Transcription Factor NFAT in Striated Muscle Development
CW Chow
Web Search

Oligo GEArray® Mouse Th1-Th2-Th3 Microarray
S Conditions - search.cosmobio.co.jp
... Transcription factor activity: Ccl5, Cebpb, Fos, Gata3, Irf1, Irf4, Jun, Junb, Jund1,
Nfatc1, Nfatc2, Nfatc3, Nfatc4, Nfkb1, Stat1, Stat4, Stat6, Tbx21, Yy1 ...
View as HTML - Web Search

[CITATION] Bio/Pharma Quarterly Journal: Volume 9, Issue 1 March, 2003
C Editors, P Executives
Web Search

NFATc1 (K-18): sc-1149
I Santa Cruz Biotechnology - genetimes.com.cn
... factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. ... T cells
(1-5). Members of the family include NFATc1 (NFATc), NFATc2 (NFATp), NFATn ...
View as HTML - Web Search

NFATc3 (P-20): sc-1154
I Santa Cruz Biotechnology - genetimes.com.cn
... factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. ... T cells
(1-5). Members of the family include NFATc1 (NFATc), NFATc2 (NFATp), NFATn ...
View as HTML - Web Search

NFATc3 (C-20): sc-1152
I Santa Cruz Biotechnology - genetimes.com.cn
... factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. ... T cells
(1-5). Members of the family include NFATc1 (NFATc), NFATc2 (NFATp), NFATn ...
View as HTML - Web Search

NFATc4 (C-20): sc-1153
I Santa Cruz Biotechnology - genetimes.com.cn
... factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. ... T cells
(1-5). Members of the family include NFATc1 (NFATc), NFATc2 (NFATp), NFATn ...
View as HTML - Web Search

Transcriptional regulation of the IL-5 gene in peripheral T cells of asthmatic patients - Full text - MIT Libraries
K OGAWA, O KAMINUMA, H OKUDAIRA, H KIKKAWA, K … - Clinical and Experimental Immunology, 2002 - blackwell-synergy.com
... The slower migrating complex contained NFATc1, NFATc2, c-Jun and c-Fos but not NFATc3,
because its formation was prevented by the addition of their specific ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Kinetics of cytokine and NFAT gene expression in human interleukin-2-dependent T lymphoblasts … - Full text - MIT Libraries
T Sareneva, S Matikainen, J Vanhatalo, K Melen, J … - Immunology, 1998 - ingentaconnect.com
... revealed by RNA hybridization, functionally monospecific bioas- expression of
c-jun, c-fos, NFATc1, NFATc2 and NFATc3 says, and monoclonal antibodies. ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling - Full text - MIT Libraries
JE Jun, CC Goodnow - Nature Immunology, 2003 - nature.com
... 19. Peng, SL, Gerth, AJ, Ranger, AM & Glimcher, LH NFATc1 and NFATc2 together control
both T and B cell activation and differentiation. ... 59. Jun, JE et al. ...
Cited by 16 - Web Search - nature.com - ncbi.nlm.nih.gov

GEArray Q series Mouse Ca2+/NF-AT Signaling Pathway Gene Array: AR-SAMM-022
FG Grouping, RT Factors, E Cebpb, NA Receptors, C … - eurogentec.be
... Members: Nfatc1, Nfatc2, Nfatc3, Nfatc4, Nfat5 Related Transcription Factors: Cebpb,
Egr2, Egr3, Fos, Fosb, Fosl1 (Fra-1), Fosl2 (Fra-2), Gata4, Jun (v-Jun ...
View as HTML - Web Search - eurogentec.com

Blockade of Nuclear Factor of Activated T Cells Activation Signaling Suppresses Balloon Injury- … - Full text - MIT Libraries
Z Liu, C Zhang, N Dronadula, Q Li, GN Rao - Journal of Biological Chemistry - jbc.org
... Jun proteins (16). In regard to expression and functional aspects of these
transcription factors, earlier studies have reported the presence of NFATc1, NFATc2, ...
Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

GEArray Q Series Human Th1-Th2-Th3 Gene Array: AR-SAHS-021.2
FG Grouping - eurogentec.com
... IL4, IL4R, IL5, JAK1, JAK3, JUNB, MAF, MHC2TA (CIITA), NFATC1 (NFATc), NFATC2 (NFATp),
NFATC3 ... ATF2, FADD (Fas), FOS, FOSL1 (Fra-1), FOSL2 (Fra-2), JUN (c-JUN ...
View as HTML - Web Search - eurogentec.be

[CITATION] The Yins of T Cell Activation
JO Liu
... Prywes, Regulatory role of MEF2D in serum induction of the c-jun promoter ... Medline];
SL Peng, AJ Gerth, AM Ranger, LH Glimcher, NFATc1 and NFATc2 together control ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Reduced expression of NFAT-associated genes in UCB versus adult CD4 T lymphocytes during primary … - Full text - MIT Libraries
BA Kaminski, S Kadereit, RE Miller, P Leahy, KR … - Blood, 2003 - bloodjournal.org
... 17-19 NFATc2 interacts with the Fos-Jun heterodimer activator protein-1 (AP-1) for
the transcriptional regulation of many genes including IL-2, IL-3, IL-4 ...
Cited by 7 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov - all 7 versions »

Transcription Cooperation by NFAT· C/EBP Composite Enhancer Complex - Full text - MIT Libraries
TT Yang, CW Chow - J. Biol. Chem, 2003 - jbc.org
... EBP -- Previous structural analysis indicated that Arg 468 , Ile 469 , and Thr 535
on the Rel homology domain of NFATc2 interact with AP-1 (Fos-Jun) to promote ...
Cited by 6 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

Calcineurin: a central controller of signalling in eukaryotes - Full text - MIT Libraries
J Aramburu, J Heitman, GR Crabtree - EMBO Reports, 2004 - emboreports.npgjournals.com
... NFAT in lymphocyte function A. Rao (Boston, MA, USA) showed that NFATc2 can induce ...
depending on whether its transcriptional partner AP-1 (Fos/Jun) is available ...
Cited by 4 - Web Search - nature.com - nature.com - ncbi.nlm.nih.gov

Cyclosporin A-sensitive induction of the Epstein-Barr virus lytic switch is mediated via a novel … - Full text - MIT Libraries
S Liu, P Liu, A Borras, T Chatila, SH Speck - The EMBO Journal, 1997 - embojournal.npgjournals.com
... necrosis factor gene promoter, Ca 2+ induction in T cells is dependent on cooperation
between NFATc2 and a heterodimer of ATF-2 and Jun (Tsai et al., 1996 ). ...
Cited by 42 - Web Search - nature.com - emboj.org - ncbi.nlm.nih.gov - all 6 versions »

[CITATION] Actin cytoskeleton regulates calcium dynamics and NFAT nuclear duration - Full text - MIT Libraries
FV Rivas, JP O’Keefe, ML Alegre, TF Gajewski - Mol. Cell. Biol, 2004
... Abs to NFATc1, NFATc2, phospho-c-Jun, phospho-Elk-1, lamin A, and lamin B were
obtained from Santa Cruz Biotechnology. Calcium flux assays. ...
Cited by 6 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 4 versions »

GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... NFAT Family Members: NFATC1, NFATC2, NFATC3, NFATC4, NFAT5. ... NIP45), FOS, FOSL1, FOXO1A,
FOXO3A, GATA3, GATA4, GRLF1, ICOS, IRF1, ISGF3G, JUN, JUNB, MADH4 ...
View as HTML - Web Search - eurogentec.be

A potential role for nuclear factor of activated T-cells in receptor tyrosine kinase and G-protein- … - Full text - MIT Libraries
CR Yellaturu, SK Ghosh, RK Rao, LK Jennings, A … - Biochem J, 2002 - biochemj.org
... Fos or Jun proteins (15). In regard to the functional role of these transcription
factors, earlier studies have reported the presence of NFATc1, NFATc2 and ...
Cited by 8 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

FK506, an immunosuppressant targeting calcineurin function
FJ Dumont - Curr. Med. Chem, 2000 - ingentaconnect.com
... that CaN may also affect the function of the c-jun N-terminal kinase, JNK ... In mature
T and B lymphocytes, NFATc1, NFATc2 and NFATc3 are co-expresssed but form ...
Cited by 42 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

[CITATION] Signal Transduction Virtual Journal - Full text - MIT Libraries
FV Rivas, JP O'Keefe, ML Alegre, TF Gajewski - Mol. Cell. Biol
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Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in … - Full text - MIT Libraries
S Jayanthi, X Deng, B Ladenheim, MT McCoy, A … - Proceedings of the National Academy of Sciences, 2005 - pnas.org
... of the three members of the Jun family of TFs, namely c-Jun, JunB, and ... These include
NFAT1 (NFATp or NFATc2), NFAT2 (NFATc1), NFAT3 (NFATc4), NFAT4 (NFATc3 or ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Role of Transcription Factor NFAT in the Immune Response
EM Kuklina, SV Shirshev - BIOCHEMISTRY (Moscow), 2001 - kluweronline.com
... Five members of NFAT family are now recognized: NFAT1 (NFATp, NFATc2), NFAT2 (NFATc,
NFATc1), NFAT3 (NFATc4), NFAT4 (NFATx, NFATc3) [811], and NFAT5 [12 ... Jun Fos ...
Cited by 4 - Web Search - springerlink.com - ncbi.nlm.nih.gov - maik.ru - Get it from MIT Libraries

GEArray Q Series Mouse Th1-Th2-Th3 Gene Array: AR-SAMM-021
FG Grouping - eurogentec.be
... ST2), Il4, Il4ra, Il5, Il9, Jak1, Jak3, Junb, Maf, Nfatc1 (NFATc), Nfatc2 (NFATp),
Nfatc2ip ... Cish5 (SOCS5), Fos, Fosl1 (Fra-1), Fosl2 (Fra-2), Jun, Jund1, Map2k7 ...
View as HTML - Web Search - eurogentec.com

Nuclear factor of activated T cells balances angiogenesis activation and inhibition - Full text - MIT Libraries
TA Zaichuk, EH Shroff, R Emmanuel, S Filleur, T … - Journal of Experimental Medicine, 2004 - jem.org
... c-Jun NH 2 -terminal kinases (JNKs) as essential upstream regulators of NFAT activity
in angiogenesis. We distinguished JNK-2 as responsible for NFATc2 ...
Cited by 5 - Web Search - jem.org - ncbi.nlm.nih.gov

MAP-kinase signaling pathways in T cells - Full text - MIT Libraries
M Rincon - Curr. Opin. Immunol, 2001 - ceiba3.cc.ntu.edu.tw
... ERK1/ERK2 JNK1/JNK2/JNK3 p38α/p38β/p38γ/p38δ Elk-1 Jun CHOP MEF2C Elk-1 SAP-1 NFATc2
NFAT4 NFATc1 Growth factors Cytokines, cell stress ATF2 Ets ...
Cited by 46 - View as HTML - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

GEArray Q Series Mouse Th1-Th2-Th3 Gene Array
FG Grouping - superarray.com
... ST2), Il4, Il4ra, Il5, Il9, Jak1, Jak3, Junb, Maf, Nfatc1 (NFATc), Nfatc2 (NFATp),
Nfatc2ip ... Cish5 (SOCS5), Fos, Fosl1 (Fra-1), Fosl2 (Fra-2), Jun, Jund1, Map2k7 ...
View as HTML - Web Search - superarray.com

GEArray Q Series Human Th1-Th2-Th3 Gene Array
FG Grouping - superarray.com
... IL4R, IL5, JAK1, JAK3, JUNB, MAF, MHC2TA (CIITA), NFATC1 (NFATc), NFATC2 (NFATp),
NFATC3 ... FOS, FOSL1 (Fra-1), FOSL2 (Fra-2), JUND, MAP2K7 (c-JUN), NAP4 (Socs-7 ...
View as HTML - Web Search - cosmobio.co.jp - cosmobio.co.jp

The Granulocyte-Macrophage Colony-Stimulating Factor/Interleukin 3 Locus is Regulated by an … - Full text - MIT Libraries
PN Cockerill, MF Shannon, AG Bert, GR Ryan, MA … - Proceedings of the National Academy of Sciences - pnas.org
... in the presence or absence of cooperative recruitment of Fos and Jun EMBO J ... Nuclear
Factor of Activated T Cells (NFAT) Transcription Factor NFATp (NFATc2) Is a ...
Cited by 71 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Two Functional Epitopes of Pigment Epithelial–Derived Factor Block Angiogenesis and Induce … - Full text - MIT Libraries
S Filleur, K Volz, T Nelius, Y Mirochnik, H Huang, … - Cancer Research, 2005 - cancerres.aacrjournals.org
... PEDF activates c-jun-NH 2 kinases (JNK), which restore NFAT inactive state ... 34-mer
causes JNK-dependent endothelial cell apoptosis due to NFATc2 deactivation and ...
Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

Multisite phosphorylation provides sophisticated regulation of transcription factors - Full text - MIT Libraries
CI Holmberg, SE Tran, JE Eriksson, L Sistonen - Trends Biochem. Sci, 2002 - mit.edu
... kinase; HIPK2, homeodomain-interacting protein kinase-2; JNK, c-Jun N-terminal ... the
C-terminal transcriptional activation domain (AD2) of NFATc2 are indicated. ...
Cited by 31 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Morphine Negatively Regulates Interferon-{gamma} Promoter Activity in Activated Murine T Cells … - Full text - MIT Libraries
J Wang, RA Barke, R Charboneau, HH Loh, S Roy - J Biol Chem, 2003 - jbc.org
... experiments, 5 µg of plasmid (NF- B p65, c-fos, NFATc1, or NFATc2) was used ... Reverse
Transcriptase-PCR Analysis of c-fos and c-jun mRNA— Splenic T cells were ...
Cited by 2 - Web Search - jbc.org - ncbi.nlm.nih.gov

Inhibitors of the calcineurin/NFAT pathway
S Martinez-Martinez, JM Redondo - Curr Med Chem, 2004 - ingentaconnect.com
... The activation of c-Jun NH 2 -terminal kinase (JNK) has been demonstrated to oppose ...
of p38 MAP kinase selectively promotes the nuclear exclusion of NFATc2 [51 ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation - Full text - MIT Libraries
N Mukerjee, KM McGinnis, ME Gnegy, KK Wang - Biochem. Biophys. Res. Commun, 2001 - mbi.ufl.edu
... by cooperatively interacting with AP-1 family members (Fos/Jun) and transacti ... protein
family consists of several isoforms; NFATp (NFAT1 or NFATc2), NFATc (NFAT2 ...
Cited by 14 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »