Nkx5-1 controls semicircular canal formation in the mouse inner ear - Full text - MIT Libraries
T Hadrys, T Braun, S Rinkwitz-Brandt, HH Arnold, E … - Development, 1998 - dev.biologists.org
... WT Fig. 4. Pax2 and Msx1 expression is unaffected in Nkx5-1 −/− mutants.
(A) The Nkx5-1 expression pattern during otic vesicle ...
Cited by 45 - Web Search - dev.biologists.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov

Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord - Full text - MIT Libraries
Y Muroyama, M Fujihara, M Ikeya, H Kondoh, S … - Genes & Development, 2002 - genesdev.org
... Primer pairs used to amplify chick LH2A, Islet1, Pax2, and Msx1 sequences were as
follows: LH2A 5', 5'-GCATTTCAATCACTCGGATG TAGCTGC-3'; LH2A 3', 5 ...
Cited by 49 - Web Search - cnc.cj.uc.pt - biology.missouri.edu - dx.doi.org - all 10 versions »

PAX2 is expressed in multiple spinal cord interneurons, including a population of EN1 interneurons … - Full text - MIT Libraries
JD Burrill, L Moran, MD Goulding, H Saueressig - Development, 1997 - dev.biologists.org
... et al., 1995) and both activate expression of Pax3, Msx1 and Slug ... analyzed cells
that express one of these transcription factors, PAX2, demonstrating multiple ...
Cited by 72 - Web Search - dev.biologists.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov

Msx1-Deficient Mice Fail to Form Prosomere 1 Derivatives, Subcommissural Organ, and Posterior …
P Fernandez-Llebrez, JM Grondona, J Perez, MF … - Journal of Neuropathology and Experimental Neurology - jneuropath.com
... interactions of several regulatory genes, among which Pax6, Pax2, Pax5, and ... Msx1
is a regulatory gene involved in epithelio-mesenchymal interactions at sites ...
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Molecular anatomy of placode development in Xenopus laevis - Full text - MIT Libraries
G SCHLOSSER, K Ahrens - Developmental Biology, 2004 - ncbi.nlm.nih.gov
... We analyzed the spatiotemporal pattern of expression of 15 transcription factors
(Six1, Six4, Eya1, Sox3, Sox2, Pax6, Pax3, Pax2, Pax8, Dlx3, Msx1, FoxI1c, Tbx2 ...
Cited by 3 - Web Search

Role of homeobox genes in normal mammary gland development and breast tumorigenesis
H Chen, S Sukumar - J Mammary Gland Biol Neoplasia, 2003 - kluweronline.com
... In the mouse, the loss-of-function alleles of Hoxc6 (12), the 9th paral- ogous Hox
(26), PAX2 (38), Msx1, and Msx2 share somedefectsinmammaryglanddevelopment(45 ...
Cited by 4 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The role of homeobox genes in kidney development
M Rauchman - Curr. Opin. Nephrol. Hypertens, 2000 - co-nephrolhypertens.com
... In contrast to Pax2 [15] and Lim1 [18] mutants, the ureteric bud grows out ... Although
Msx1 and Msx2 single mutants do not exhibit a kidney phenotype, the double ...
Cited by 5 - Web Search - co-nephrolhypertens.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Stem cell biology and neurodegenerative disease - Full text - MIT Libraries
RD McKay - Philos Trans R Soc Lond B Biol Sci, 2004 - journals.royalsoc.ac.uk
... by Shh (sonic hedgehog) co-treatment; inhibition of Shh by cyclopamine promotes
induction of Bmpr-1b and Msx1. ... En-1 / Pax2 En-1 / Otx2 En-1 / Bf1 En-1 / TH ...
Cited by 8 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Pax3 and Pax7 are expressed in commissural neurons and restrict ventral neuronal identity in the … - Full text - MIT Libraries
A Mansouri, P Gruss - Mech. Dev, 1998 - invivo.caltech.edu
... V1 interneurons and corroborated by a distinct change in the Pax2 and Lim1 ... Specifically,
the expression of dorsal markers like the homeobox genes msx1 and msx2 ...
Cited by 41 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Extensive Cell Movements Accompany Formation of the Otic Placode - Full text - MIT Libraries
A Streit - Developmental Biology, 2002 - kcl.ac.uk
... stages reveals molecular heterogeneity of otic precursor cells in terms of their
expression of dlx5, msx1, Six4, and ERNI. Although Pax2 expression coincides ...
Cited by 18 - View as HTML - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity - Full text - MIT Libraries
B Kammandel, K Chowdhury, A Stoykova, S Aparicio, … - Dev. Biol, 1999 - fbmc.fcen.uba.ar
Page 1. Distinct cis-Essential Modules Direct the Time– Space Pattern of
the Pax6 Gene Activity Birgitta Kammandel, Kamal Chowdhury ...
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DLX 5 positions the neural crest and preplacode region at the border of the neural plate - Full text - MIT Libraries
K McLarren, A Litsiou, A Streit - Developmental Biology, 2003 - kcl.ac.uk
... Mishima and Tomarev, 1998), GATA3 (Sheng and Stern, 1999), epidermal keratin GK19
(Sato and Yasugi, 1997), MSX1 (Liem et al., 1995), PAX2 (Acces- sion No. ...
Cited by 15 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Brief clinical report: Wolf-Hirschhorn syndrome and a split hand malformation - Full text - MIT Libraries
M Bamshad, JR O’Quinn, JC Carey - American Journal of Medical Genetics, 1998 - doi.wiley.com
... on the homology between segments of mouse and human chromosomes, Pax2, fibroblast
growth fac ... Msx2 and the closely related gene Msx1 were originally isolated by ...
Cited by 2 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Axial specification for sensory organs versus non-sensory structures of the chicken inner ear - Full text - MIT Libraries
DK Wu, FD Nunes, D Choo - Development, 1998 - dev.biologists.org
... This is an unexpected result given that many genes implicated in pattern formation,
such as Msx1, Otx1 and Pax2 (Nornes et al., 1990; Torres et al., 1996), are ...
Cited by 25 - Web Search - wwwlib.bionet.nsc.ru - dev.biologists.org - ncbi.nlm.nih.gov - all 5 versions »

The transcription factor Pax6 is required for development of the diencephalic dorsal midline … - Full text - MIT Libraries
G Estivill-Torrus, T Vitalis, P Fernandez-Llebrez, … - Mech. Dev, 2001 - uma.es
... the underlying SCO are tightly related to one another and that these structures
are under the control of regulatory genes such as Pax2, Pax5, Pax6 and Msx1. ...
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Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential … - Full text - MIT Libraries
PJ Gage, SA Camper - Mol. Endocrinol, 2005 - hmg.oupjournals.org
... defects in several human anomalies, including PAX2 (renal-coloboma syndrome), PAX3
(Waardenberg syndrome type I), PAX6 (aniridia), MSX1 (selective tooth ...
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Transcription factors in dysmorphology - Full text - MIT Libraries
D Lacombe - Clinical Genetics, 1999 - blackwell-synergy.com
... A human MSX1 homeodomain mutation causes selective dominant tooth agenesis involving
second ... Mutations of the PAX2 gene have been found in an autosomal dominant ...
Web Search - ncbi.nlm.nih.gov

Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling … - Full text - MIT Libraries
O Michos, L Panman, K Vintersten, K Beier, R … - Development, 2004 - smbs.buffalo.edu
... Genetic analysis in the mouse shows that the Wt1 and Pax2 transcription factors
(Kreidberg ... Msx1 and Msx2 are targets of BMP signaling in the limb bud and can ...
Cited by 6 - View as HTML - Web Search - dev.biologists.org - dev.biologists.org - ncbi.nlm.nih.gov

Specification of dorsal spinal cord interneurons - Full text - MIT Libraries
AW Helms, JE Johnson - Curr. Opin. Neurobiol, 2003 - staging.healthsystem.virginia.edu
... Probably ventral ? ? Lbx1 Lhx1/5 Pax2 Lbx1 Lmx1b Rnx Brn3a Laminae I-III Class A ...
bHLH genes ventral cell fates Msx1 Math1 Ngn1/2 Wnt1/Wnt3a Zic1 BMPs ? ...
Cited by 28 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

A new human homeobox gene OGI 2 X is a member of the most conserved homeobox gene family and is … - Full text - MIT Libraries
E Semina, RS Reiter, JC Murray - Human Molecular Genetics, 1998 - hmg.oupjournals.org
... proteins) have been described in a number of human disorders: PAX2 in a ... PAX3 in
Waardenburg syndrome; PAX6 in aniridia and Peter's anomaly; MSX1 in familial ...
Cited by 10 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Conserved and muscle group-specific gene expression patterns shape postnatal development of the … - Full text - MIT Libraries
G Cheng, AP Merriam, B Gong, P Leahy, S Khanna, JD … - Physiological Genomics, 2004 - physiolgenomics.physiology.org
... development and/or are responsive to retinoic acid (eg, Pax2, 25%; Msx1,
23%; Hoxa3, 21%; Znf42, 19%; Pitx2, 15%; Tfap2a, 10%; Pbx1 ...
Web Search - dx.doi.org - ncbi.nlm.nih.gov - ijmm.org - all 5 versions »

GENETICS OF CRANIOFACIAL DEVELOPMENT AND MALFORMATION - Full text - MIT Libraries
AOM Wilkie, GM Morriss-Kay - Nature Reviews Genetics, 2001 - nature.com
... 56. Torres, M., Gómez-Pardo, E. & Gruss, P. Pax2 contributes to inner ear patterning
and optic nerve trajectory. Development 122, 3381-3391 (1996). ...
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The bHLH factor Olig 3 coordinates the specification of dorsal neurons in the spinal cord - Full text - MIT Libraries
T Muller, K Anlag, H Wildner, S Britsch, M Treier, … - Genes & Development, 2005 - genesdev.org
... E,F), Lbx1 (red) and -gal (green) (G,H), Lhx1/5 (red) and Pax2 (green) (I ... Lmx1a
expression marks the roof plate, whereas Msx1 is expressed in cells in and near ...
Web Search - dx.doi.org - genesdev.org - ncbi.nlm.nih.gov

Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, …
EV Semina, R Reiter, NJ Leysens, WLM Alward, KW … - Nature Genetics, 1996 - nature.com
... Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies ...
N., Guthua, SW, Seidman, JG & Seidman, CE A human MSX1 homeodomain missense ...
Cited by 188 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Eya 1 expression in the developing ear and kidney: Towards the understanding of the pathogenesis of … - Full text - MIT Libraries
V Kalatzis, I Sahly, A El-Amraoui, C Petit - Developmental Dynamics, 1998 - doi.wiley.com
... F: Pax2 expression is detected at the periphery and, at a lower level, in the ... of
one or two of the ossicles, for example, the malleus for Msx1 (Satokata and ...
Cited by 26 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

First Genomic Localization of Oculo-Oto-Dental Syndrome with Linkage To Chromosome 20q13. - Full text - MIT Libraries
H Vieira, K Gregory-Evans, N Lim, JL Brookes, LA … - Investigative Ophthalmology and Visual Science, 2002 - iovs.org
... Molecular Genetic Assessment Candidate loci encompassing the developmental genes
PAX6, PAX2, TGFB2, DLX2, BMP4, RIEG1, ODD, MSX1, HOXC, PDGFRA, DLX3, HOXA1 ...
Cited by 1 - Web Search - iovs.org - iovs.org - ncbi.nlm.nih.gov - all 5 versions »

Comparative genomics provides evidence for an ancient genome duplication event in sh
JS Taylor, Y Van de Peer, I Braasch, A Meyer - Phil. Trans. R. Soc. Lond. B, 2001 - journals.royalsoc.ac.uk
Page 1. Comparative genomics provides evidence for an ancient genome duplication
event in sh John S. Taylor, Yves Van de Peer, Ingo Braasch and Axel Meyer * ...
Cited by 102 - Web Search - evolutionsbiologie.uni-konstanz.de - mit.edu - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Msx-1 and Msx-2 in Mammary Gland Development
K Satoh, E Ginsburg, BK Vonderhaar - Journal of Mammary Gland Biology and Neoplasia, 2004 - kluweronline.com
... Like Msx1, Msx2 activates cyclin D1 expression and inhibits cellular differentiation
as ... In the mouse mammary gland, the paired-box gene, Pax2, is required for ...
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Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo - Full text - MIT Libraries
CE Erter, TP Wilm, N Basler, CV Wright, L Solnica- … - Development, 2001 - dev.biologists.org
... to induce expression of the posterior-lateral neural markers pax3 and msx1, in
neuralized ... stage and applied to in situ hybridization using six3, pax2.1, krx20 ...
Cited by 42 - Web Search - invivo.caltech.edu - dev.biologists.org - ncbi.nlm.nih.gov

Amphioxus and ascidian Dmbx homeobox genes give clues to the vertebrate origins of midbrain … - Full text - MIT Libraries
T Takahashi, PWH Holland - Development, 2004 - dev.biologists.org
... A Ci-Pax2/5/8-A riboprobe was synthesised with a fluorescein RNA Labeling Mix ... PRD
class), but only 38-42% identity with human HOXA1, EN1 and MSX1 (members of ...
Cited by 2 - Web Search - dx.doi.org - dev.biologists.org - ncbi.nlm.nih.gov

BMP signaling patterns the dorsal and intermediate neural tube via regulation of homeobox and helix- … - Full text - MIT Libraries
JR Timmer, C Wang, L Niswander - Development, 2002 - dev.biologists.org
... Pax6 expression is refined by the BMP-mediated activation of Msx1, which represses ...
dorsal border of Dbx1-expressing cells may help divide the Pax2 + , Lim1/2 ...
Cited by 28 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

A novel missense mutation in the paired domain of PAX 9 causes non-syndromic oligodontia - Full text - MIT Libraries
D Jumlongras, JY Lin, A Chapra, CE Seidman, JG … - Human Genetics, 2004 - springerlink.com
... intron boundaries of the two genes and were able to exclude MSX1. ... conditions and
contains significant similarities to consensus sequences for Pax2, Pax3, and ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes … - Full text - MIT Libraries
M Dottori, MK Gross, P Labosky, M Goulding - Development, 2001 - dev.biologists.org
... These include Pax3, Pax7, Msx1/2 and Zic1-Zic3, all of which have ... NeuN (Chemicon
International), monoclonal anti-P0 (1E8, DSHB), polyclonal anti-Pax2 (Zymed Lab ...
Cited by 33 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Deregulated homeobox gene expression in cancer: cause or consequence? - Full text - MIT Libraries
C Abate-Shen - Nature Reviews Cancer, 2002 - nature.com
... Nature 360, 477-481 (1992). Shows that overpression of Msx1 (formerly Hox-7.1) in
cell culture blocks differentiation and promotes a transformed phenotype. ...
Cited by 38 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Genetic and biochemical diversity in the Pax gene family - Full text - MIT Libraries
DA Underhill - Biochem Cell Biol, 2000 - article.pubs.nrc-cnrc.gc.ca
... 1995) and Pax2 ... In the dermomyotome, Msx1 appears to antago- nize Pax3 activity through
a protein–protein interaction that occurs via the paired domain, and ...
Cited by 11 - Web Search - dx.doi.org - pubs.nrc-cnrc.gc.ca - ncbi.nlm.nih.gov - all 6 versions »

Transcriptional Control of the Cell Cycle in Mammary Gland Development and Tumorigenesis
RD Coletta, P Jedlicka, A Gutierrez-Hartmann, HL … - Journal of Mammary Gland Biology and Neoplasia, 2004 - springerlink.com
... This consequence may be due to the effect of Msx1 on other cell cycle components ...
One of the members of this fam- ily, Pax2, is necessary for the progesterone ...
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Molecular Genetics of Septo-Optic Dysplasia
MT Dattani, JP Martinez-Barbera, PQ Thomas, JM … - Hormone Research, 2000 - content.karger.com
... human anomalies, including PAX2 (renal coloboma syndrome) [21], PAX3 (Waardenberg
syndrome type I) [22, 23, 24], PAX6 (aniridia) [25], MSX1 (selective tooth ...
Cited by 5 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Molecular aspects of vertebrate retinal development
SS Zhang, XY Fu, CJ Barnstable - Mol. Neurobiol, 2002 - biomed.humanapress.com
... Pax2 expression was increased by the secreted factor sonic hedgehog (Shh), or a ... Other
transcription factors, such as Lhx2, Msx1, Msx2 and Vax2, have been ...
Cited by 9 - Web Search - neurosci.humanapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Intrarenal cells, not bone marrow–derived cells, are the major source for regeneration in … - Full text - MIT Libraries
F Lin, A Moran, P Igarashi - J. Clin. Invest, 2005 - jci.org
... In cells that express Pax2, the cyclin-dependent kinase inhibitor p21 is ... markers
when the homeobox-containing transcriptional repressor msx1 is expressed ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - jci.org

Emx2 and Pax6 Function in Cooperation with Otx2 and Otx1 to Develop Caudal Forebrain Primordium That … - Full text - MIT Libraries
J Kimura, Y Suda, D Kurokawa, ZM Hossain, M … - The Journal of Neuroscience, 2005 - jneurosci.org
... Lhx5 (Sheng et al., 1997 ), Lim1 (Fujii et al., 1994 ), Msx1 (Hill et al., 1989 ),
Ngn2 (Sommer et al., 1996 ), Otx2 (Matsuo et al., 1995 ), Pax2 (Dressler et ...
Web Search - jneurosci.org - ncbi.nlm.nih.gov

Five Nkx 5 genes show differential expression patterns in anlagen of sensory organs in medaka: … - Full text - MIT Libraries
M Adamska, A Wolff, M Kreusler, J Wittbrodt, T … - Development Genes and Evolution, 2001 - springerlink.com
... rooted with related sequences (mouse proteins Nkx2–5, NM_008700, Msx1, NM_010835,
and ... This situation is reminiscent of two other paralogous genes: Pax2.1 and ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid - Full text - MIT Libraries
PX Xu, W Zheng, C Laclef, P Maire, RL Maas, H … - Development, 2002 - dev.biologists.org
... and Eya1 –/– embryos at E9.5. No significant difference of Msx1 expression was ... double
mutants, and in the otic epithelium and kidney of Pax2/Pax8 double ...
Cited by 24 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

A novel mammalian wnt gene, WNT 8 B, shows brain-restricted expression in early development, with … - Full text - MIT Libraries
M Lako, S Lindsay, P Bullen, DI Wilson, SC Robson, … - Human Molecular Genetics, 1998 - hmg.oupjournals.org
... expression patterns expected of Wnt gene regulators, eg expression of the Pax2 homeobox
gene ... in vitro by the homeodomain of the product of the Msx1 gene, a ...
Cited by 11 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Genetic analysis of Gremlin functions during mouse organogenesis
O Michos - 2004 - dspace.library.uu.nl
... Misexpression of the BMP targets Msx1 in ... fail to activate Pax2 , which is in turn
also essential for metanephric kidney development (Torres et al., 1995). ...
View as HTML - Web Search - dspace.library.uu.nl

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
Page 1. BioSystems xxx (2005) xxx–xxx A statistical analysis of the TRANSFAC database
Gary B. Fogel a , Dana G. Weekes a , Gabor Varga b , Ernst R. Dow b , ...
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Comprehensive survey of carapacial ridge-specific genes in turtle implies co-option of some …
S Kuraku, R Usuda, S Kuratani - Evolution and Development, 2005 - blackwell-synergy.com
... This idea prompted researchers to examine the expression of Msx1, fibroblast growth
factor (Fgf)10, and Fgf8 (Loredo et al. 2001; Vincent et al. ...
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Evolution of neural crest and placodes: amphioxus as a model for the ancestral vertebrate? - Full text - MIT Libraries
LZ HOLLAND, ND HOLLAND - Journal of Anatomy, 2001 - journals.cambridge.org
... Nevertheless, the ex- pression of the ascidian homologues of Pax2\5\8 in the ascidian
atrial primordia has been taken in support of their homology with the ...
Cited by 33 - Web Search - journals.cambridge.org - blackwell-synergy.com - ncbi.nlm.nih.gov

Sensory organ development in the inner ear: molecular and cellular mechanisms
J Bryant, RJ Goodyear, GP Richardson - British Medical Bulletin, 2002 - bmb.oupjournals.org
... Also Pax2 -/- mice fail to form a cochlear duct 16 . ... These include BMP5 and BMP7
23 , p75NGFR 24 ,25 , Msx1 17 , NT3 18 ,24 , bmp2b 19 , and MsxC 19 ,26 . ...
Cited by 13 - Web Search - mcgrathlab.urmc.rochester.edu - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

Induction of inner ear fate by FGF3 - Full text - MIT Libraries
V Vendrell, E Carnicero, F Giraldez, MT Alonso, T … - Development, 2000 - dev.biologists.org
Page 1. INTRODUCTION The head ectoderm of vertebrates develops three pairs
of sensory placodes, nose, lens and inner ear from anterior ...
Cited by 44 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Transcriptional networks regulating neuronal identity in the developing spinal cord - Full text - MIT Libraries
SK Lee, SL Pfaff - Nat. Neurosci, 2001 - nature.com
... Nature 398, 622-627 (1999). | Article | PubMed | ISI | ChemPort |; Burrill, JD,
Moran, L., Goulding, MD & Saueressig, H. PAX2 is expressed in multiple spinal ...
Cited by 52 - Web Search - nature.com - cb207.med.harvard.edu - ncbi.nlm.nih.gov - all 6 versions »