Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPalpha and GATA … - Full text - MIT Libraries
B Heavey, C Charalambous, C Cobaleda, M Busslinger - EMBO J, 2003 - embojournal.npgjournals.com
... 3887-3897, 2003 © European Molecular Biology Organization Myeloid lineage switch
of Pax5 mutant but not wild-type B cell progenitors by C/EBP and GATA factors. ...
Cited by 10 - Web Search - nature.com - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia - Full text - MIT Libraries
R Hubmann, JD Schwarzmeier, M Shehata, M Hilgarth, … - Blood, 2002 - bloodjournal.org
... core promoter region revealed a complex array of potential regulatory elements,
including CBF1, STAT6, NF- B, Pax5 (BSAP), Ikaros, GATA1-3, LMO2, and MZF1. ...
Cited by 17 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of … - Full text - MIT Libraries
KAM Hanna, J Klintman, H Yang, H Hock, TM … - Nature, 2003 - nature.com
... M. & Busslinger, M. Reversion of B cell commitment upon loss of Pax5 expression. ...
The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA ...
Cited by 51 - Web Search - nature.com - ncbi.nlm.nih.gov

The origin of hematopoietic cell type diversity - Full text - MIT Libraries
T Hoang - Oncogene, 2004 - nature.com
... HSC CLP CMP GMP MEP B G M Meg Ery T Ery P LMO2 E2A E2A, Pax5 HEB, GATA3
Pro-B Pro-T PU.1 C/EBPα C/EBPβ SCL, GATA-1 FOG SCL Figure ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Oligo GEArray® Human Hematopoietic Stem Cells and Hematopoiesis Microarray
S Conditions - search.cosmobio.co.jp
... INHBA, JAG1, MAL, MAP4K1, MLF1, NCOA6, NOTCH1, NOTCH2, NOTCH4, PAX5, PF4, RASGRP4 ...
DLL1, ERAF, FEZ2, FUT10, IFI16, IL10, IL20, IL31RA, JAG1, LMO2, MLF1, MMP9 ...
View as HTML - Web Search

The‘definitive’(and‘primitive’) guide to zebrafish hematopoiesis - Full text - MIT Libraries
AJ Davidson, LI Zon - Oncogene, 2004 - nature.com
... (2000b) ldb1 LIM domain binding — Toyama et al. (1998) lmo2 LIM domain — Thompson
et al. (1998) pax5 Paired domain, homeobox — Pfeffer et al. (1998) ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Transcription Factors: Normal and Malignant Development of Blood Cells
IJ Hematol - Int J Hematol, 2001 - cardenjennings.metapress.com
... chapters, and includes information about Ikaros, PU.1, Pax5(BSAP), Janus ... TEL/ETV6,
mixed lineage leukemia (MLL), coacti- vators, LMO2, and acetyltransferases ...
Web Search

Differentiation Mechanisms and Malignancy
GI Abelev - BIOCHEMISTRY (Moscow), 2000 - protein.bio.msu.ru
... list of master genes of the hemopoietic system includes PU1 and LMO2 which control ...
by functioning of the specific mas- ter genes; for example, E2A/PAX5/Id are ...
Cited by 3 - View as HTML - Web Search - protein.bio.msu.su - ncbi.nlm.nih.gov - maik.rssi.ru - all 6 versions » - Get it from MIT Libraries

ORIGINAL ARTICLE Gene Expression Profiles of Cutaneous B Cell Lymphoma - Full text - MIT Libraries
MN Storz, M van de Rijn, YH Kim, S Mraz-Gernhard, … - Journal of Investigative Dermatology, 2003 - blackwell-synergy.com
... transcription factors necessary for certain stages in B cell development (PAX5,
TCL1, Oct ... ICOS, BLR1 (CXCR5), BCA-1 (CXCL13), RGS13, BCL7A, BCL11A, LMO2] (Fig 2 ...
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The Ews-ERG Fusion Protein Can Initiate Neoplasia from Lineage-Committed Haematopoietic Cells - Full text - MIT Libraries
R Codrington, R Pannell, A Forster, LF Drynan, A … - PLoS Biol, 2005 - medicine.plosjournals.org
... on Cre-mediated deletion of a loxP-flanked (floxed) segment of the Lmo2 gene [36 ...
Pax5 and CD3 primers [38] were used for specific detection of B cell and T cell ...
Cached - Web Search - plme.allenpress.com - biology.plosjournals.org - pubmedcentral.nih.gov - all 5 versions »

Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment - Full text - MIT Libraries
T Miyamoto, H Iwasaki, B Reizis, M Ye, T Graf, IL … - Dev. Cell, 2002 - unb.br
... In myeloid set 2, both Lmo2 and GATA-2 play a critical role in primary hematopoiesis,
and depletion of either ... Lmo2 GATA-2 0 3 0 0 preB cells (Figure 4A). ...
Cited by 58 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... 14 The Role of Pax5 (BSAP) in Early and Late B-Cell Development 217 ... 27 The LMO2 Master
Gene; Its Role as a Transcription Regulator Determining Cell Fate in ...
Web Search

ORIGINAL PAPER ES02. 01 Transcriptional regulation of haematopoiesis - Full text - MIT Libraries
B Goettgens - Vox Sanguinis, 2004 - blackwell-synergy.com
... MafB v Ets-1, C/EBP v FOG-1, C/EBP v PU.1 and Pax5 v Notch1 ... It also is unlikely to
be a coincidence that five transcription factors (SCL, LMO2, Runx-1, Tel and ...
Web Search - ncbi.nlm.nih.gov

Epithelial-mesenchymal transition and progression of oral carcinomas
K Imai, T Okuse, T Chiba, M Morikawa, K Sanada - cancer-therapy.org
... Kozmik Z, Sure U, Ruedi D, Busslinger M, Aguzzi A. (1995) Deregulated expression
of PAX5 in medulloblastoma. ... (1997) The LIM-only protein Lmo2 is a bridging ...
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Molecular and Genetic Mechanisms of Lymphomagenesis
R Kušec - cmj.hr
... neoplasm – type 1 and type 2. Type 1 are translocations involv- ing LMO2, TAL2,
and TAL1 ... leukemia, Bcl6 of t(3;14) in diffuse large cell lymphoma, Pax5 of t(9 ...
View as HTML - Web Search - cmj.hr

Transcriptional regulation of haematopoiesis - Full text - MIT Libraries
B Goettgens - Vox Sanguinis, 2004 - ingentaconnect.com
... MafB v Ets-1, C/EBPβ v FOG-1, C/EBPα v PU.1 and Pax5 v Notch1 ... It also is unlikely
to be a coincidence that five transcription factors (SCL, LMO2, Runx-1, Tel ...
Web Search

Gradient of E2A activity in B-cell development - Full text - MIT Libraries
S Herblot, PD Aplan, T Hoang - Mol Cell Biol, 2002 - mcb.asm.org
... activation of a specific gene in childhood T-cell acute lymphoblastic leukemia
(T-ALL) (reviewed in reference 5). SCL collaborates with LMO1 or LMO2 to induce ...
Cited by 23 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

Lineage plasticity and commitment in T-cell development - Full text - MIT Libraries
EV Rothenberg, CJ Dionne - Immunological Reviews, 2002 - blackwell-synergy.com
... of committed myeloid precursors (45), and there is lower expression of Pax5 in fetal ...
SCL/Tal-1 and its interaction partners, Lmo1 and Lmo2, which positively ...
Cited by 8 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Report A Dynamic Switch in the Replication Timing of Key Regulator Genes in Embryonic Stem Cells …
P Perry, S Sauer, N Billon, WD Richardson, M … - landesbioscience.com
... Scl (4; C7) Sox1 (8; A2) Oct4 (17; B3) Lmo2 (2; E2) Sox2 (3; B) Nanog (6; F2) ... Ebf
(11; B1.1) Msx1 (5; B2) Cripto (9; F2) Pax5 (4; B2) Pax3 (1; - ) Fgf4 (7; F5) ...
Web Search - landesbioscience.com

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... not CAGG LMO2COM 01 Complex of Lmo2 bound to Tal-1, E2A proteins, and
GATA-1, half-site 1 Core should be CAGGTG not CAGG E47 01 ...
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[BOOK] Transcription factors: normal and malignant development of blood cells
K Ravid, J Licht - 2001 - print.google.com
... 14 The Role of Pax5 (BSAP) In Early and Late B-Cell Development 217 ... 27 The LMO2 Master
Gene; Its Role as a Transcription Regulator Determining Cell Fate in ...
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E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause … - Full text - MIT Libraries
DB Sykes, MP Kamps - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... in E2a-deficient mice (3) or in mice coexpressing SCL/Tal1 and LMO2 (29) or ... are required
for more restricted development, and some, such as Pax5, are required ...
Cited by 4 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cytogenetics and molecular genetics of acute lymphoblastic leukemia - Full text - MIT Libraries
CJ Harrison, L Foroni - Reviews in Clinical and Experimental Hematology, 2002 - blackwell-synergy.com
... In the PAX5/ETV6 fusion gene, the paired-box domain of PAX5 and both the ... The genes
TAL2, LYL1, LMO1, LMO2, cMYC, LCK, TAN1, IGH, TCL1 and BCL3 are involved in ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

Annual Report 2002-2003
FP Board - 2003 - crg.es
Page 1. Annual Report 2002-2003 SCIENTIFIC BOARD Page 2. CENTRE DE REGULACIÓ GENÒMICA
Annual Report 2002-2003 SCIENTIFIC BOARD Design by Estudi Freixes ...
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Clinical and biological importance of cytogenetic abnormalities in childhood and adult acute …
B Johansson, F Mertens, F Mitelman - Annals of Medicine, 2004 - dx.doi.org
Page 1. Clinical and biological importance of cytogenetic abnormalities
in childhood and adult acute lymphoblastic leukemia Bertil ...
Web Search - taylorandfrancis.metapress.com - ncbi.nlm.nih.gov - lu-research.lub.lu.se - Get it from MIT Libraries

Transcriptional Control of T Lymphocyte Differentiation - Full text - MIT Libraries
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - Stem Cells, 2001 - stemcells.alphamedpress.org
... Lmo2 and GATA-3 associated expression in intraembryonic hemogenic sites. ... Commitment
to the B-lymphoid lineage depends on the transcription factor Pax5. ...
Cited by 17 - Web Search - dx.doi.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

The bloody fate of endothelial stem cells - Full text - MIT Libraries
H Kubo, K Alitalo - Development, 2003 - dx.doi.org
... Reversion of B cell commitment upon loss of Pax5 expression. ... The T cell leukemia
LIM protein Lmo2 is necessary for adult mouse hematopoiesis. Proc. Natl. Acad. ...
Cited by 10 - Web Search - genesdev.org - genesdev.org - ncbi.nlm.nih.gov - all 5 versions »

S tem C ells
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - immuneweb.xxmc.edu.cn
Page 1. Transcriptional Control of T Lymphocyte Differentiation F RANK
JT S TAAL , a F LOOR W EERKAMP , a A NTON W. L ANGERAK , a ...
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Role of Helix-Loop-Helix Proteins in Lymphocyte Development
C MURRE - Cold Spring Harbor Symposia on Quantitative Biology, 1999 - dx.doi.org
... HLH protein, tal-1, and the LIM domain-containing pro- teins, LMO1 and LMO2. ... Es-
sential functions of Pax5 (BSAP) in pro-B cell development: Difference between ...
Cited by 3 - Web Search - cshl-symposium.org - cshl-symposium.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Quantitative real-time PCR for cancer detection: the lymphoma case
A Staahlberg, N Zoric, P Aaman, M Kubista - Expert Rev. Mol. Diagn, 2005 - future-drugs.com
... patients. Out of the 36 genes, six (LMO2, BCL6, FN1, CCND2, SCYA3 and BCL2)
were found to be strong predic- tors for survival. Other ...
Web Search - future-drugs.com - tataa.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

BLOOD - Full text - MIT Libraries
RA Shivdasani, SH Orkin - Blood, 1996 - bloodjournal.org
... call for due caution in interpreting the results of gene knockouts in a single mouse
train.4' A DIFFERENTIATION ARREST PHENOCOPY THE CASE OF rbtn2/LMO2 The Lim ...
Web Search

Jak 3, severe combined immunodeficiency, and a new class of immunosuppressive drugs - Full text - MIT Libraries
M Pesu, F Candotti, M Husa, SR Hofmann, LD … - Immunological Reviews, 2005 - blackwell-synergy.com
Full Article. View/Print PDF article (4063K). Download to reference manager.
Immunological Reviews Volume 203 Issue 1 Page 127 - February ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Exploitation of stem cell plasticity - Full text - MIT Libraries
E Martin-Rendon, SM Watt - Transfusion Medicine, 2003 - blackwell-synergy.com
Full Article. View/Print PDF article (295K). Download to reference manager.
Transfusion Medicine Volume 13 Issue 6 Page 325 - December ...
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C01.
W Aberer, C Foti, JD Johansen, S Seidenari, F … - DERMATITIS - blackwell-synergy.com
Page 1. COURSES C01 CONTACT AND OCCUPATIONAL DERMATITIS C01.1 New allergens W. Aberer
Department of Dermatology, University of Graz, Graz, Austria ...
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Marko Pesu Fabio Candotti Matthew Husa Sigrun R. Hofmann - Full text - MIT Libraries
LD Notarangelo, JJ O’Shea - Immunological Reviews, 2005 - ingentaconnect.com
Page 1. Jak3, severe combined immunodeficiency, and a new class of
immunosuppressive drugs Marko Pesu Fabio Candotti Matthew Husa ...
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