Contribution of BCAP to maintenance of mature B cells through c-Rel - Full text - MIT Libraries
T Yamazaki, T Kurosaki - Nature Immunology, 2003 - nature.com
... Grumont, RJ & Gerondakis, S. The murine c-rel proto-oncogene encodes two mRNAs ... PL
& Busslinger, M. Control of pre-BCR signaling by Pax5-dependent activation of ...
Cited by 11 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Corecruitment of the Grg 4 repressor by PU. 1 is critical for Pax 5-mediated repression of B-cell- … - Full text - MIT Libraries
Y Linderson, D Eberhard, S Malin, A Johansson, M … - EMBO Reports, 2004 - emboreports.npgjournals.com
... in COS-7 cells derived from the p 34SV–wt construct when regulated by the
overexpression of p50/c-Rel, PU.1, Pax5 and Grg4 as indicated above each lane. ...
Cited by 4 - Web Search - nature.com - emboreports.npgjournals.com - ncbi.nlm.nih.gov - all 5 versions »

scientificreport
A Vienna - nature.com
... showing the b-globin signal (b) in COS-7 cells derived from the pb34SV–wt construct
when regulated by the overexpression of p50/c-Rel, PU.1, Pax5 and Grg4 as ...
Web Search - nature.com

Concerted repression of an immunoglobulin heavy-chain enhancer, 3'alpha E (hs1, 2) - Full text - MIT Libraries
M Singh, BK Birshtein - Immunology, 1996 - dx.doi.org
... and CM Snapper NF-{kappa}B/p50 and NF-{kappa}B/c-Rel differentially regulate ... A.
Emelyanov, M. Singh, N. Ashouian, and BK Birshtein BSAP (Pax5)-Importin alpha 1 ...
Cited by 20 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Plasma cells: finding new light at the end of B cell development - Full text - MIT Libraries
KL Calame - Nat Immunol, 2001 - nature.com
... 7. Nutt, SL, Heavey, B., Rolink, AG & Busslinger, M. Commitment to the B-lymphoid
lineage depends on the transcription factor Pax5. Nature 401, 556-562 (1999). ...
Cited by 72 - Web Search - cumicro2.cpmc.columbia.edu - hora.cpmc.columbia.edu - ncbi.nlm.nih.gov - all 7 versions »

Table 3. Verification of SAGE tags matching to multiple UniGene clusters by GLGI
ID UniGene - pnas.org
... CAGGGAGAAA. PAX5. 2. Hs. 22030. 0. 4. CATTTTGCTT. PAX5. 2. Hs. 22599. 1. 29. GCTCACCCTT.
AIP1. 2. ... GLUR. 2. Hs. 44313. 0. 7. GTGGTACGTG. REL. 2. Hs. 44865. 0. 83. ...
Web Search

Decision making in the immune system: Lymphoid Malignancies: the dark side of B-cell differentiation - Full text - MIT Libraries
AL Shaffer, A Rosenwald, LM Staudt - Nature Reviews Immunology, 2002 - nature.com
... | Article | PubMed | ISI | ChemPort |. 45. Pahl, HL Activators and target genes
of Rel/NF- B transcription factors. Oncogene 18, 6853-6866 (1999). ...
Cited by 31 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cellular Origins of Hodgkin's Disease. - Full text - MIT Libraries
LM Staudt - The Journal of Experimental Medicine, 2000 - dx.doi.org
... Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. ...
Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal ...
Cited by 35 - Web Search - jem.org - intl.jem.org - lymphochip.nih.gov - all 6 versions »

Large B-cell lymphoma with Hodgkin's features - Full text - MIT Libraries
JF Garcia, M Mollejo, M Fraga, J Forteza, JA … - Histopathology, 2005 - blackwell-synergy.com
... of classical HL, such as CD30 and/or CD15, and coexpression of PAX5 and MUM1 ... In all
cases assessed by c-REL/p65 immunohistochemistry, the protein was mainly ...
Web Search - ingentaconnect.com

Transcriptional regulation of B-cell differentiation - Full text - MIT Libraries
T Reya, R Grosschedl - Curr. Opin. Immunol, 1998 - inv.his.se
... Both p50 and p65 subunits of NF-κB belong to the Rel family of transcription
factors, which also includes p52, RelB and c-Rel. ...
Cited by 48 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

PRDM 1/Blimp-1 is expressed in human B-lymphocytes committed to the plasma cell lineage - Full text - MIT Libraries
G Cattoretti, C Angelin-Duclos, R Shaknovich, H … - The Journal of Pathology, 2005 - doi.wiley.com
... c-Rel (NF-kB) Oncogene Research Rabbit Ab-1 G 1 : 2000 Ref [17] cMYC SCBT Rabbit
sc-764 G 1 µ g/ml Ref [31] ... PAX5 SCBT Goat C-20 sc1974 G 1 µ g/ml Datasheet ...
Web Search - ncbi.nlm.nih.gov

Pathobiology of Primary Mediastinal B-Cell Lymphoma
S PILERI, P ZINZANI, G GAIDANO, B FALINI, P … - Leukemia and Lymphoma, 2003 - dx.doi.org
... there are few data describing the expression of MUM1/IRF4, PAX5/BSAP, BCL ... gains in
segments of chromosome 9p, including amplification of the REL proto-oncogene ...
Cited by 1 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com

NF-{kappa} B and Oct-2 Synergize to Activate the Human 3'Igh hs4 Enhancer in B Cells - Full text - MIT Libraries
MA Sepulveda, AV Emelyanov, BK Birshtein - The Journal of Immunology, 2004 - jimmunol.org
... 1 or Pax5) regulated human hs4 enhancer activity. ChIP data for BL-2 cells have
confirmed the endogenous binding of NF- B family members, p50 and Rel-B, and of ...
Cited by 2 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Molecular regulation of class switch recombination to IgE through germline transcription - Full text - MIT Libraries
S Monticelli, D Vercelli - Allergy, 2001 - ingentaconnect.com
... NF-kB/Rel proteins and their association with STAT6 The region immediately downstream
of the IL-4RE contains two sites that bind NF-kB/Rel proteins with ...
Cited by 7 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Current list of HBD fusion proteins
GR APETALA, GR CONSTANS, FBS FosB-L, ER Gal, MR GR … - picard.ch
... M., Petrenko, O., Roll, R. & Enrietto, PJ A chicken c-Rel-estrogen receptor ... PL &
Busslinger, M. Control of pre-BCR signaling by Pax5-dependent activation of ...
View as HTML - Web Search - picard.ch

cis-Element clustering correlates with dose-dependent pro-and antisignaling effects of IL18 - Full text - MIT Libraries
D Leyfer, A Bond, E Tworog, D Perron, S Maska, A … - Genes and Immunity, 2004 - nature.com
... CREB. PAX5 is the deciding factor in B-cell commit- ment, 27 while CREB
together with REL are involved in T- cell activation. 28 ...
Web Search - zlab.bu.edu - nature.com - ncbi.nlm.nih.gov

Regeneration of Inner Ear Cells from Stem Cell PrecursorsA Future Concept of Hearing Rehabilitation?
S Dazert, C Aletsee, D Brors, H Sudhoff, AF Ryan, … - DNA and Cell Biology, 2003 - dx.doi.org
... B cells from mice carrying a targeted dele- tion in the Pax5 gene can ... Rel- atively
little attention has been directed to the possibilityof trans- plantation to ...
Cited by 2 - Web Search - liebertonline.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Relationship of viral infections to wheezing illnesses and asthma - Full text - MIT Libraries
JE Gern, WW Busse - Nature, 2000 - nature.com
... M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. ...
For viruses such as rhinoviruses,which infect rel- atively few cells in the ...
Cited by 16 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia - Full text - MIT Libraries
R Hubmann, JD Schwarzmeier, M Shehata, M Hilgarth, … - Blood, 2002 - bloodjournal.org
... of the CD23a gene instead of a canonical TATA box argues for Pax5 (BSAP) as ...
Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression ...
Cited by 17 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Epstein-Barr Virus Nuclear Antigen 2 Specifically Induces Expression of the B-Cell Activation … - Full text - MIT Libraries
F Wang, CD Gregory, M Rowe, AB Rickinson, D Wang, … - J. Virol, 2004 - pnas.org
... Is Activated by RFX Proteins and the B-Cell-Specific Activator Protein BSAP/Pax5
J. Virol ... S. Banga, A. Rivera, DW Ballard, Y. Ron, and C. Gélinas Rel/NF-kappa ...
Cited by 67 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 5 versions »

A target selection of somatic hypermutations is regulated similarly between T and B cells upon … - Full text - MIT Libraries
A Kotani, I Okazaki, M Muramatsu, K Kinoshita, NA … - Proceedings of the National Academy of Sciences, 2005 - pnas.org
... and their expression in lymphocyte is not reported, whereas GATA3 and c-rel are
expressed ... So far, nine genes (Ig , IgH, MB-1(Ig ), B29(Ig ), PAX5, BCL6, c-MYC ...
Web Search - dx.doi.org - pnas.org - ncbi.nlm.nih.gov - all 5 versions »

TRANSCRIPTIONAL REGULATION DURING B CELL DEVELOPMENT - Full text - MIT Libraries
A Henderson, K Calame - Annual Review of Immunology, 1998 - dx.doi.org
... stage. BSAP (PAX5). BSAP is a member of the paired-box homeodomain family
of transcription factors. BSAP ... 99). NF- B/REL PROTEINS. The ...
Cited by 65 - Web Search - immunol.annualreviews.org - immunol.annualreviews.org - ncbi.nlm.nih.gov

Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced … - Full text - MIT Libraries
MH Lind, B Rozell, RPA Wallin, M van Hogerlinden, … - Proc Natl Acad Sci US A, 2004 - pubmedcentral.nih.gov
... We have earlier shown that selective inhibition of Rel/NF-kB signaling in the ... Of
interest is also the infiltration of B220(+) Pax5(-) cells with dendritic ...
Cited by 3 - Web Search - dx.doi.org - pnas.org - ncbi.nlm.nih.gov - all 6 versions »

Recognition of specific DNA sequences - Full text - MIT Libraries
CW Garvie, C Wolberger - Mol. Cell, 2001 - qb.fcen.uba.ar
... similar to C·G. transcription factors, the common element among the various
subfamilies such as the Rel homology domain As many have ...
Cited by 21 - View as HTML - Web Search - wisc.edu - ncbi.nlm.nih.gov - all 4 versions »

Comparative genomics provides evidence for an ancient genome duplication event in sh
JS Taylor, Y Van de Peer, I Braasch, A Meyer - Phil. Trans. R. Soc. Lond. B, 2001 - journals.royalsoc.ac.uk
Page 1. Comparative genomics provides evidence for an ancient genome duplication
event in sh John S. Taylor, Yves Van de Peer, Ingo Braasch and Axel Meyer * ...
Cited by 102 - Web Search - evolutionsbiologie.uni-konstanz.de - mit.edu - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

B-cell antigen-receptor signalling in lymphocyte development - Full text - MIT Libraries
LD Wang, MR Clark, B Radeloff, K Laun, M Zirra, A … - Immunology, 2003 - blackwell-synergy.com
... Conversely, ectopic expression of BLNK in Pax5 / µ + cells, which are deficient
in BLNK ... The transcription factors NF- B and c-Rel are important; 135 deletion ...
Cited by 5 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Yin Yang 1 Is a Lipopolysaccharide-Inducible Activator of the Murine 3'Igh Enhancer, hs3 - Full text - MIT Libraries
SJ Gordon, S Saleque, BK Birshtein - The Journal of Immunology, 2003 - jimmunol.org
... Octamer, Pax5, and B families of binding complexes form the constellation of
transcription ... LPS induced binding of NF- B family members p50 and c-Rel, as well ...
Cited by 5 - Web Search - cellbio.aecom.yu.edu - jimmunol.org - ncbi.nlm.nih.gov - all 6 versions »

[PS] CITATIONS FOR PROTEIN/DNA (REGULATORY) - Full text - MIT Libraries
PDA White, X Ding, JC Vanderspek, JR Murphy, D … - J. Biol. Chem, 2004 - aist.go.jp
... PD0222 DB.Huang, YQ.Chen, M.Ruetsche, CB.Phelps, G.Ghosh X-ray Crystal Structure
of Proto-Oncogene Product c-Rel Bound to the CD28 Response Element of IL-2 ...
Cited by 10 - View as HTML - Web Search - ndbserver.rutgers.edu - ndbserver.rutgers.edu

Molecular basis of Stat1 and PU. 1 cooperation in cytokine-induced Fc {gamma} receptor I promoter …
S Aittomaki, J Yang, EW Scott, MC Simon, O … - Int. Immunol. 16, 2004 - intimm.oupjournals.org
... Several transcription factors such as GATA-1, EKLF, GATA-3, Pax5, TCF-1, Ikaros,
E2A and PU ... RI, Ig H and L chain genes, Btk [reviewed in (18,20)], and c-rel (21 ...
Cited by 1 - Web Search - intimm.oupjournals.org - intimm.oupjournals.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Molecular and Genetic Mechanisms of Lymphomagenesis
R Kušec - cmj.hr
... MALT 13 PAX5 t(9;14)(p13;q32) translocation involving class switch recombination
mechanism LPL 14 ... ALCL 22 REL 2p13 gene amplification DLBCL 23 ...
View as HTML - Web Search - cmj.hr

Cell cycle deregulation in B-cell lymphomas - Full text - MIT Libraries
M Sanchez-Beato, A Sanchez-Aguilera, MA Piris - Blood, 2003 - bloodjournal.org
... 35 . c-REL is also amplified in primary ... H 89 . PAX5, a member of the
paired-box gene family, encodes a B-cell specific transcription ...
Cited by 43 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

The Transcription Factor NF-kappa B/p 50 Interacts with the blk Gene during B Cell Activation - Full text - MIT Libraries
P Zwollo, S Rao, JJ Wallin, ER Gackstetter, ME … - J Biol Chem, 1998 - jbc.org
... that in mammals contains the protein members p50, p65, p52, c-Rel, and RelB ... The
anti-p65, anti-Pax5, and anti-Sp1 antibodies were detected using a horseradish ...
Cited by 10 - Web Search - jbc.org - ncbi.nlm.nih.gov

The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies - Full text - MIT Libraries
TG Willis, MJ Dyer - Blood, 2000 - bloodjournal.org
... encodes the protein products p52 and p100, members of the Rel/nuclear factor (NF)-
B family. Marginal zone lymphomas. t(9;14)(p13;q32) paired homeobox 5 (PAX5). ...
Cited by 73 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A novel mutation (Q40P) in PAX8 associated with congenital hypothyroidism and thyroid hypoplasia: … - Full text - MIT Libraries
T Congdon, LQ Nguyen, CR Nogueira, RL Habiby, G … - J Clin Endocrinol Metab, 2001 - jcem.endojournals.org
... The proximal promoter (beginning at 1248 rel- ative to the translation initiation
codon) was ... of a glu- tamine that is conserved among PAX2, PAX5, and PAX8 by ...
Cited by 25 - Web Search - jcem.endojournals.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

The molecular pathogenesis of high grade non-Hodgkin’s lymphoma
MJS Dyer, R Siebert, TG Willis, B Schlegelberger - haematologica.org
... with the exception of t(9;14) (p13;q32), which was observed in 4 cases; whether
this translocation involves the PAX5 gene as ... REL/BCL11 and MYC, respectively. ...
View as HTML - Web Search - haematologica.it

Metastatic medulloblastoma—therapeutic success through molecular target identification?
MC Fruehwald, C Plass - The Pharmacogenomics Journal, 2002 - nature.com
... 5 Due to its prognostic rel- www.nature.com/tpj ... PAX5 9p13 Paired box gene 5.
Upregulation in medulloblastomas; no expression in developing cerebellum. ...
Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Expression of the AID protein in normal and neoplastic B cells - Full text - MIT Libraries
L Pasqualucci, R Guglielmino, J Houldsworth, J … - Blood, 2004 - bloodjournal.org
... as defined by the presence of mutations in PIM1, PAX5, cMYC, and ... Relationship between
REL amplification, REL function, and clinical and biologic features in ...
Cited by 6 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov

Primary Mediastinal B-Cell Lymphoma - Full text - MIT Libraries
SA Pileri, G Gaidano, PL Zinzani, B Falini, P … - American Journal of Pathology, 2003 - ajp.amjpathol.org
... concerning the occurrence of some molecules, such as CD10, MUM1/IRF4, PAX5/BSAP
(B-cell ... consist in C-MYC mutations, detection of BCL-2 and REL proto-oncogene ...
Cited by 14 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

WORKSHOP ABSTRACTS
G Enblad, K Jchrens, I Anagnostopoulos, H Stein, K … - blackwell-synergy.com
... Conclusion: Our study demonstrates that CD43 and PAX5 are able to distinguish between ...
CGH data) were subsequently subjected to FICTION using the REL, STAT3/5a ...
Web Search - ingentaconnect.com

TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... 201 Sridhar Rao and M. Celeste Simon 14 The Role of Pax5 (BSAP) in Early and Late
B-Cell Development 217 Markus Horcher, Dirk Eberhard, and Meinrad Busslinger ...
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cDNA Microarray Analysis of Macroregenerative and Dysplastic Nodules in End-Stage Hepatitis C Virus- …
RA Anders, LM Yerian, M Tretiakova, JM Davison, RJ … - J Pathol, 2003 - ajp.amjpathol.org
... PAX5 is involved in organogenesis through HOX gene expression. ... Therefore, PAX5
appears to be significantly up-regulated in MRNs and DNs. ...
Cited by 10 - Web Search - fgf.bsd.uchicago.edu - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Genes, pathways and checkpoints in lymphocyte development and homeostasis - Full text - MIT Libraries
LA MIOSGE, CC GOODNOW - Immunology and Cell Biology, 2005 - ingentaconnect.com
... The transcription factor Pax5 is required for B cell commit- ment and maturation. ...
15 B cells in pax5- deficient mice undergo arrest at the pro-B/pre-BI stage. ...
Web Search

REGULATORY MECHANISMS THAT DETERMINE THE DEVELOPMENT AND FUNCTION OF PLASMA CELLS - Full text - MIT Libraries
KL Calame, KI Lin, C Tunyaplin - Annual Review of Immunology, 2003 - immunol.annualreviews.org
... Transcription factors Bcl-6 and Pax5, which are required for germinal center B cells,
block plasmacytic differentiation and repress Blimp-1 and XBP-1 ... Pax5. ...
Cited by 38 - Web Search - phyto.annualreviews.org - nutr.annualreviews.org - ncbi.nlm.nih.gov - all 6 versions »

Antisense Phosphorothioate Oligonucleotides to the p65 Subunit of NF-kB Abrogate Fulminant Septic … - Full text - MIT Libraries
JF SCHLAAK, AP BARREIROS, S PETTERSSON, P … - Scand. J. Immunol, 2001 - ingentaconnect.com
... Mice lacking the c-rel ... Science 1996;274:782±4. 22 Neurath MF, Max EE, Strober W.
Pax5 (BSAP) regulates the murine immunoglobulin 3 H alpha enhancer by ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov

Cloning of human early B-cell factor and identification of target genes suggest a conserved role in … - Full text - MIT Libraries
R Gisler, SE Jacobsen, M Sigvardsson - Blood, 2000 - bloodjournal.org
... to interact with and regulate the promoters of several genes in the mouse pre-B
cell, ie, the mb-1, 38 , 39 B29, 40 5, 41 , 42 VpreB, 42 , 43 and Pax5 44 , 45 ...
Cited by 16 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

An interfering form of Blimp-1 increases IgM secreting plasma cells and blocks maturation of … - Full text - MIT Libraries
C Angelin-Duclos, K Johnson, J Liao, KI Lin, K … - European Journal of Immunology, 2002 - doi.wiley.com
... C-myc [16], CIITA [13], Pax5 [17] and many other genes [18] have recently been shown
to be targets of Blimp-1-dependent repres- sion during plasma cell ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

POSITIVE VERSUS NEGATIVE SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS - Full text - MIT Libraries
JI Healy, CC Goodnow - Annual Review of Immunology, 1998 - immunol.annualreviews.org
... B cells because B cells lacking one or both copies of the c-rel gene have ... 1 and J
chain, as well as preventing the characteristic decrease in Pax5 and CD72 ...
Cited by 123 - Web Search - immunol.annualreviews.org - ncbi.nlm.nih.gov

Primary Mediastinal B-Cell Lymphoma - Full text - MIT Libraries
R Articles - American Journal of Pathology, 2003 - ajp.amjpathol.org
... concerning the occurrence of some molecules, such as CD10, MUM1/IRF4, PAX5/BSAP
(B-cell ... consist in C-MYC mutations, detection of BCL-2 and REL proto-oncogene ...
Web Search

Ho me o box genes: a mole cu lar link betwe en deve lop ment and cancer Ge nes home o box: uma rela …
IDUCTI ON - Pesqui Odontol Bras, 2003 - scielo.br
... disease 26 ; PAX3 has a role in rhabdomyosarcomas 2 and mela no mas 31 ; PAX5 deter-
mines ... G, Barba P, Odartchen ko N, Givel JC, Freschi G, Buc ci a rel li G ...
View as HTML - Web Search - scielo.br

Signatures of the immune response - Full text - MIT Libraries
AL Shaffer, A Rosenwald, EM Hurt, JM Giltnane, LT … - Immunity, 2001 - lymphochip.nih.gov
... Gene expression signatures are described in detail in the text. and CD72) and
transcription factors (PAX5, OCT-2, IL-1 , LARC, MCP-1, GRO2). ...
Cited by 72 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »