Transcriptional control of B-cell development - Full text - MIT Libraries
M Schebesta, B Heavey, M Busslinger - Curr Opin Immunol, 2002 - inv.his.se
... progress has recently been made in our understanding of how transcription factors
such as PU.1, Notch1, E2A, EBF, Pax5, Bcl6, Blimp1 and XBP1 control different ...
Cited by 45 - View as HTML - Web Search - unb.br - ingentaconnect.com - all 6 versions »

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases … - Full text - MIT Libraries
AL Shaffer, M Shapiro-Shelef, NN Iwakoshi, AH Lee, … - Immunity, 2004 - lymphochip.nih.gov
... Blimp-1 was required for maximal induction of Ig clearly elucidated for two plasma
cell genes, J chain and xbp1, both of which are repressed by PAX5 (Reimold ...
Cited by 11 - View as HTML - Web Search - pathology.wustl.edu - ncbi.nlm.nih.gov

Regulation of plasma-cell development - Full text - MIT Libraries
M Shapiro-Shelef, K Calame - Nature Reviews Immunology, 2005 - nature.com
... of X-box-binding protein 1 (XBP1) 34 , the IgH, the IgL and the immunoglobulin joining
(J) chain 35–37 provides a mechanism for how PAX5 blocks plasma-cell ...
Cited by 1 - Web Search - immuneweb.xxmc.edu.cn - ncbi.nlm.nih.gov

长寿命浆细胞相关特性及调控机制
姜萍萍, 姜广水, 张立军 - edu.cn
... 亡？本文讨论的问题强调浆细胞寿命的维持必需BLIMP1 和XBP1
的持续表达及PAX5、 BCL-6 和MTA3 的持续缺乏 ...
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Birth pangs: the stressful origins of lymphocytes - Full text - MIT Libraries
S Pillai - J. Clin. Invest, 2005 - jci.org
... in collaboration with B lymphocyte–induced maturation protein 1 (Blimp-1; which
represses the PAX5 inhibitor), enhances the transcription of XBP1, which is ...
Web Search - pubmedcentral.nih.gov - jci.org - ncbi.nlm.nih.gov

Building an antibody factory: a job for the unfolded protein response - Full text - MIT Libraries
JW Brewer, LM Hendershot - Nature Immunology, 2005 - nature.com
... Bcl6 and Pax5, a transcriptional regulator required for B lin- eage commitment and
a repressor both of immunoglobulin and J chain genes 56 and of XBP1 (ref. ...
Web Search - nature.com - ncbi.nlm.nih.gov

Restraint of B Cell Activation by Foxj1-Mediated Antagonism of NF-{kappa} B and IL-6 - Full text - MIT Libraries
L Lin, SL Brody, SL Peng - The Journal of Immunology, 2005 - jimmunol.org
... Real-time PCR detection of Foxj1, IL-6, CD80, CD86, ICOS, ICOSL, CD40, CD154,
bcl-6, Blimp-1, IRF-4, Mitf, c-myc, Pax5, and Xbp1 were performed as described ...
Web Search - jimmunol.org - jimmunol.org - jimmunol.org

Progress in Hematology
JD Shaughnessy Jr - cardenjennings.metapress.com
... transcription factors important in regulating PC development, eg, IRF4, BCL6, CIITA,
STAT6, and PAX5, notably did not show the down- regulation seen with XBP1. ...
Web Search

Primer on Medical Genomics Part IX: Scientific and Clinical Applications of DNA Microarrays— … - Full text - MIT Libraries
J Shaughnessy Jr - Mayo Clin Proc, 2003 - nas.cl.uh.edu
... other transcription factors important in regulating PC development, eg, IRF4, BCL6,
CIITA, STAT6, and PAX5, did not show the down-regulation seen with XBP1. ...
Cited by 4 - View as HTML - Web Search - mayo.edu - sanbi.ac.za - nbn.ac.za - all 8 versions »

2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin(TCDD) Alters the Regulation of Pax 5 in Lipopolysaccharide- … - Full text - MIT Libraries
BS Yoo, DR Boverhof, D Shnaider, RB Crawford, TR … - Toxicological Sciences, 2004 - toxsci.oupjournals.org
... Cooperation of Pax2 and Pax5 in midbrain and cerebellum development. ... XBP1 mRNA is
induced by ATF6 and spliced by IRE1 in response to ER stress to produce a ...
Cited by 2 - Web Search - bch.msu.edu - ingentaconnect.com - ncbi.nlm.nih.gov - all 10 versions »

PRDM 1/Blimp-1 is expressed in human B-lymphocytes committed to the plasma cell lineage - Full text - MIT Libraries
G Cattoretti, C Angelin-Duclos, R Shaknovich, H … - The Journal of Pathology, 2005 - doi.wiley.com
... PRDM1 was expressed in germinal centre blasts that co-express Pax5, CD19, CD20,
and CD10, but not BCL6 or MTA-3. Pax5 was downregulated and full plasma cell ...
Web Search - ncbi.nlm.nih.gov

Transcriptional regulatory cascades controlling plasma cell differentiation - Full text - MIT Libraries
KI Lin, C Tunyaplin, K Calame - Immunological Reviews, 2003 - blackwell-synergy.com
... cells, these studies have led to the important concept that plasmacytic differentiation
involves repression of regulators, such as Bcl-6 and Pax5, that are ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Modular nature of Blimp-1 in the regulation of gene expression during B cell maturation - Full text - MIT Libraries
R Sciammas, MM Davis - J. Immunol, 2004 - jimmunol.org
... 1 in M12 cells, suggesting a parallel pathway with Xbp1 and the ... Interestingly, the
homeodomain transcription factor Pax5, aB cell lineage identity factor, is ...
Cited by 6 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Interpreting the molecular biology and clinical behavior of multiple myeloma in the context of … - Full text - MIT Libraries
JD Shaughnessy, B Barlogie - Immunological Reviews, 2003 - blackwell-synergy.com
... Other transcription factors important in regulating PC development, eg IRF4, BCL6,
CIITA, STAT6, and PAX5, did not show the downregulation seen in XBP1. ...
Cited by 12 - Web Search - blackwell-synergy.com - ncbi.nlm.nih.gov

Expression of the AID protein in normal and neoplastic B cells - Full text - MIT Libraries
L Pasqualucci, R Guglielmino, J Houldsworth, J … - Blood, 2004 - bloodjournal.org
... lacking ( ) ASHM, as defined by the presence of mutations in PIM1, PAX5, cMYC, and ...
up-regulation of post-GC markers such as IRF4 and XBP1, overall suggesting a ...
Cited by 6 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov

Kuo-I Lin Chainarong Tunyaplin Kathryn Calame - Full text - MIT Libraries
KI Lin - Immunological Reviews, 2003 - ingentaconnect.com
... cells, these studies have led to the important concept that plasmacytic differentiation
involves repression of regulators, such as Bcl-6 and Pax5, that are ...
Web Search

John D. Shaughnessy Jr Bart Barlogie - Full text - MIT Libraries
JD Shaughnessy Jr - Immunological Reviews, 2003 - ingentaconnect.com
... Other transcription factors important in regulating PC development, eg IRF4, BCL6,
CIITA, STAT6, and PAX5, did not show the downregulation seen in XBP1. ...
Web Search

REGULATORY MECHANISMS THAT DETERMINE THE DEVELOPMENT AND FUNCTION OF PLASMA CELLS - Full text - MIT Libraries
KL Calame, KI Lin, C Tunyaplin - Annual Review of Immunology, 2003 - immunol.annualreviews.org
... Transcription factors Bcl-6 and Pax5, which are required for germinal center B cells,
block plasmacytic differentiation and repress Blimp-1 and XBP-1 ... Pax5. ...
Cited by 38 - Web Search - phyto.annualreviews.org - nutr.annualreviews.org - ncbi.nlm.nih.gov - all 6 versions »

STAT 5 regulates the self-renewal capacity and differentiation of human memory B cells and controls … - Full text - MIT Libraries
FA Scheeren, M Naspetti, S Diehl, R Schotte, M … - Nature Immunology, 2005 - nature.com
... repressor protein Blimp-1 (refs. 5–8), and Xbp1, the gene encoding the
X-box transcription factor XBP-1 (ref. 9). In contrast, memory ...
Web Search - nature.com - hawaii.edu - ncbi.nlm.nih.gov

Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory … - Full text - MIT Libraries
M Shapiro-Shelef, KI Lin, LJ McHeyzer-Williams, J … - Immunity, 2003 - molbio.grad.uiowa.edu
... Functional Blimp-1 binding sites have been identified on several direct targets
including c-myc, CIITA promoter III, Pax5, SpiB, and Id3 (Lin et ...
Cited by 30 - View as HTML - Web Search - ncbi.nlm.nih.gov

The unfolded protein response sensor IRE1 {alpha} is required at 2 distinct steps in B cell … - Full text - MIT Libraries
K Zhang, HN Wong, B Song, CN Miller, D Scheuner, … - J. Clin. Invest, 2005 - jci.org
... in B cell lymphopoiesis in which IRE1 -mediated splicing of the XBP1 mRNA is ... and
the gene encoding the B cell–specific activator protein Pax5/BSAP, play ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - jci.org - ncbi.nlm.nih.gov

The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the … - Full text - MIT Libraries
NN Iwakoshi, AH Lee, LH Glimcher - Immunological Reviews, 2003 - blackwell-synergy.com
Full Article. View/Print PDF article (1543K). Download to reference manager.
Immunological Reviews Volume 194 Issue 1 Page 29 - August ...
Cited by 14 - Web Search - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... TCF11MAFG 01 TCF11/MafG heterodimers TH1E47 01 Thing1/E47 heterodimer TST1 01
POU-factor Tst-1/Oct-6 USF 02 Upstream stimulating factor VMAF 01 v-Maf XBP1 01 ...
View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

TranSignal TM Protein/DNA Arrays
PU Manual, MA MA1014 - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays Cat. # MA1010, MA1011, MA1012 Product User
Manual, MA1013 & MA1014, MA1015 Released 09/28/04 Panomics, Inc. ...
View as HTML - Web Search - biocat.de

Evidence for Selective Transformation of Autoreactive Immature Plasma Cells in Mice Deficient in … - Full text - MIT Libraries
JQ Zhang, C Okumura, T McCarty, MS Shin, P … - The Journal of Experimental Medicine - jem.org
... splenic B cells, the levels of Sdc1 (CD138), Xbp1, and Prdm1 (Blimp) were generally
found to increase from PL to SJL to PCT, whereas those for Pax5, Bcl6, Cd19 ...
Cited by 1 - Web Search - dx.doi.org - jem.org - ncbi.nlm.nih.gov

The use of genetic microarray analysis to classify and predict prognosis in haematological … - Full text - MIT Libraries
AP Levene, GJ Morgan, FE Davies - Clinical and Laboratory Haematology, 2003 - blackwell-synergy.com
... of several essential B cell transcription factors including c-MYC, CIITA, Id3 PAX5
and Spi ... biology such as syndecan 1, BCMA, PIM2, MUM1/IRF4 and XBP1 and novel ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TranSignal TM Protein/DNA Arrays
CS Version - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays (Column Separation Version) Cat. #
MA1210, MA1211, MA1212l, MA1213 & MA1214, MA1215 Product ...
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Neal N. Iwakoshi Ann-Hwee Lee Laurie H. Glimcher - Full text - MIT Libraries
NN Iwakoshi, AH Lee - Immunological Reviews, 2003 - ingentaconnect.com
Page 1. The X-box binding protein-1 transcription factor is required for plasma
cell differentiation and the unfolded protein response ...
Web Search

Autoinhibitory Domains: Modular Effectors - Full text - MIT Libraries
MA Pufall, BJ Graves - Annu. Rev. Cell Dev. Biol, 2002 - cellbio.annualreviews.org
Page 1. Annu. Rev. Cell Dev. Biol. 2002. 18:421–62 doi: 10.1146/annurev.cellbio.
18.031502.133614 Copyright c 2002 by Annual Reviews. ...
Cited by 18 - Web Search - astro.annualreviews.org - ncbi.nlm.nih.gov

Annual Review of Cell and Developmental Biology - Full text - MIT Libraries
MA Pufall, BJ Graves - Annual Review of Cell and Developmental Biology, 2002 - cellbio.annualreviews.org
Annual Reviews tagline graphic, ...
Web Search - astro.annualreviews.org - nutr.annualreviews.org