Evolution of transcription factor function
CC Hsia, W McGinnis - Curr Opin Genet Dev, 2003 - www-biology.ucsd.edu
... This may have imposed stronger selection pressure on Hoxa3 to coevolve with ... the imaginal
disc primordia of adult Drosophila structures, mouse Pax6 protein can ...
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Hox 3 genes coordinate mechanisms of genetic suppression and activation in the generation of … - Full text - MIT Libraries
GO Gaufo, KR Thomas, MR Capecchi - Development, 2003 - capecchi.genetics.utah.edu
... Materials and methods Mouse lines Mice harboring mutations for Hoxb1, Hoxa3, Hoxb3,
Hoxd3 and Pax6 were previously reported (Ericson et al., 1997; Gaufo et al ...
Cited by 8 - View as HTML - Web Search - dx.doi.org - dev.biologists.org - ncbi.nlm.nih.gov - all 5 versions »

Somatic motoneurone specification in the hindbrain: the influence of somite-derived signals, … - Full text - MIT Libraries
S Guidato, F Prin, S Guthrie - Development, 2003 - dev.biologists.org
... The localisation and level of Nkx2.2 expression failed to change following Hoxa3
overexpression (Fig. 6L), whereas Pax6 expression was repressed to a modest ...
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Contribution of Hox genes to the diversity of the hindbrain sensory system - Full text - MIT Libraries
GO Gaufo, S Wu, MR Capecchi - Development, 2004 - capecchi.genetics.utah.edu
... expressing noradrenergic visceral interneurons in Hoxb1 –/– and Hoxa3 –/– b3 –/–
mutant ... spinal cord, for example, the loss of Pax6 is associated ...
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Detecting Conserved Regulatory Elements with the Model Genome of the Japanese Puffer Fish, Fugu … - Full text - MIT Libraries
S Aparicio, A Morrison, A Gould, J Gilthorpe, C … - Proceedings of the National Academy of Sciences - pnas.org
... comparison and transgenic analysis redefine the functional domain of PAX6 Hum ...
Independent regulation of initiation and maintenance phases of Hoxa3 expression ...
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Requirement for downregulation of kreisler during late patterning of the hindbrain - Full text - MIT Libraries
T Theil, L Ariza-McNaughton, M Manzanares, J … - Development, 2002 - dev.biologists.org
... By analogy, the ectopic expression of Hoxa3 and Hoxb3 in r3 should result in ... An
analogous situation is suggested by studies of Pax6 gene function in the ...
Cited by 9 - Web Search - caradhras.iib.uam.es - dev.biologists.org - ncbi.nlm.nih.gov

Postnatal Lethality in Mice Lacking the Sax2 Homeobox Gene Homologous to Drosophila S59/slouch: … - Full text - MIT Libraries
R Simon, T Lufkin - Mol Cell Biol, 2003 - pubmedcentral.nih.gov
... Pax6 controls progenitor cell identity and neuronal fate in response to ... Independent
regulation of initiation and maintenance phases of Hoxa3 expression in the ...
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Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid - Full text - MIT Libraries
PX Xu, W Zheng, C Laclef, P Maire, RL Maas, H … - Development, 2002 - dev.biologists.org
... Hoxa3, a member of the Hox gene family, which specifies positional identity in the
developing embryo (Krumlauf, 1994 ), is expressed in both 3rd and 4th ...
Cited by 24 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Regulation of mouse lens fiber cell development and differentiation by the Maf gene - Full text - MIT Libraries
BZ Ring, SP Cordes, PA Overbeek, GS Barsh - Development, 2000 - dev.biologists.org
... of β-crystallins, which are first expressed after Pax6 expression has ... in vitro studies
indicate that Krml1 directly activates transcription of Hoxa3 and Hoxb3 ...
Cited by 56 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Full Article - Full text - MIT Libraries
FR Goodman, PJ Scambler - Clinical Genetics, 2001 - blackwell-synergy.com
... deletion in HOXA3 [21], and may well be due to haploinsufficiency for HOXA3. ... Similar
mutations in other homeodomain proteins, such as PAX6 [28], EMX2 [29 ...
Web Search - blackwell-synergy.com

The mouse Gene Expression Database(GXD): updates and enhancements - Full text - MIT Libraries
DP Hill, DA Begley, JH Finger, TF Hayamizu, IJ … - Nucleic Acids Research, 2004 - nar.oupjournals.org
... looks like in animals that are mutant for the Hoxa3 gene’ or ‘What data is available
describing the expression of genes in the eyes of Pax6 mutants?’ The ...
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Downregulation of mafB Expression in T-Helper Cells During Early Differentiation In Vitro - Full text - MIT Libraries
H Hashizume, H Hamalainen, Q Sun, A Sucharczuk, R … - Scandinavian Journal of Immunology, 2003 - blackwell-synergy.com
... Interactions between mafs and Pax6 (paired domain-containing) and Hox (homeodomain ...
examples include the regulation of transferrin receptor, Hoxa3, Hoxb3 and p53 ...
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Limb anomalies and craniofacial syndromes II. Gene regulation of morphogenetic and dysmorphogenetic …
FN Synodinos, MJ Papagrigorakis - grortho.gr
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59 ∞ӈ̷ϛ˜ ÙˆÓ ¿ÎÚˆÓ Î·È Û‡Ó‰ÚÔÌ· ÙÔ ...
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Expression of Sox3 throughout the developing central nervous system is dependent on the combined … - Full text - MIT Libraries
S Brunelli, ES Casey, D Bell, R Harland, R Lovell- … - Genesis, 2003 - doi.wiley.com
... The -Gal expression is not confined to the proliferating progenitor cells in the
ventricular zone, marked by the expression of SOX3 itself, PAX6, and BrdU ...
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spiel ohne grenzen/pou2 is required for zebrafish hindbrain segmentation - Full text - MIT Libraries
G Hauptmann, HG Belting, U Wolke, K Lunde, I Soll, … - Development, 2002 - dev.biologists.org
... et al., 1994 ) and has been shown to be a direct regulator of Hoxa3 and Hoxb3 in ...
E), and spg m793 (F) embryos at 1 dpf that were assayed for pax6.1 expression ...
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Members of the Large Maf Transcription Family Regulate Insulin Gene Transcription in Islet ß Cells - Full text - MIT Libraries
T Matsuoka, L Zhao, I Artner, HW Jarrett, D … - Mol. Cell. Biol, 2003 - mcb.asm.org
... 1). Moreover, mutations in Pdx-1 (68), BETA2 (32), and Pax6 (81) caused ... and distinct
roles of kreisler in regulation of the paralogous Hoxa3 and Hoxb3 genes. ...
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Mechanisms of pattern formation in development and evolution - Full text - MIT Libraries
I Salazar-Ciudad, J Jernvall, SA Newman - Development, 2003 - dev.biologists.org
... Pax6 is a transcription factor known to affect the expression of adhesion molecules
and in the mouse brain, during stages E9.0-E12.5 (Stoykova et al., 2000 ...
Cited by 9 - Web Search - biocenter.helsinki.fi - nymc.edu - ncbi.nlm.nih.gov - all 7 versions »

Additional hox clusters in the zebrafish: divergent expression patterns belie equivalent activities …
AEE Bruce, AC Oates, VE Prince, RK Ho - Evolution and Development, 2001 - blackwell-synergy.com
... Greer et al. demonstrated that Hoxa3 and Hoxd3 are functionally equivalent in the
mouse though they share only 50% amino acid sequence identity (Greer et al. ...
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Neural crest cell plasticity and its limits - Full text - MIT Libraries
NM Le Douarin, S Creuzet, G Couly, E Dupin - Development, 2004 - dev.biologists.org
... skeletal structures is abolished (completely for Hoxa2, and partly for Hoxa3 and
Hoxb4 ... like gene expression pattern, such as that of Shh and Pax6 (Schneider and ...
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Activation of Stem-Cell Specific Genes by HOXA9 and HOXA10 Homeodomain Proteins in CD34 Human Cord …
CM Ferrell, ST Dorsam, H Ohta, RK Humphries, MK … - stemcells.alphamedpress.org
... Identification of differentially expressed genes in mouse Pax6 heterozygous lenses ...
hindbrain: the influence of somite-derived signals, retinoic acid and Hoxa3. ...
Web Search - dx.doi.org - stemcells.alphamedpress.org

Hox 11 paralogous genes are essential for metanephric kidney induction - Full text - MIT Libraries
DM Wellik, PJ Hawkes, MR Capecchi - Genes & Development, 2002 - genesdev.org
... 1999 ), and mice mutant for Eya1, Hoxa3, or Pax9 are athymic, aparathyroid, and ... Eya
homologs of the Drosophila eyes absent gene require Pax6 for expression in ...
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A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... OCT1 Q6 Octamer factor 1 P300 01 p300 PAX3 B Pax3 binding sites PAX4 01 Pax-4 binding
sites PAX4 03 Pax-4 binding sites PAX4 04 Pax-4 binding sites PAX6 01 Pax ...
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A 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly - Full text - MIT Libraries
FR Goodman, F Majewski, AL Collins, PJ Scambler - Am J Hum Genet, 2002 - journals.uchicago.edu
... entire HOXA cluster has a phenotype attributable to haploinsufficiency for just
HOXA3 and HOXA13 ... of a 300-kb deletion starting in intron 10 of the PAX6 gene in ...
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Regulation of Hoxa2 in cranial neural crest cells involves members of the AP-2 family - Full text - MIT Libraries
M Maconochie, R Krishnamurthy, S Nonchev, P Meier, … - Development, 1999 - dev.biologists.org
... a number of other transcription factors, including AP-2α, Pax3, Pax6 Msx1, Dlx 2 ...
previously used transgenic analysis to scan the Hoxa2-Hoxa3 intergenic region ...
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Phosphorylation of MafA is essential for its transcriptional and biological properties - Full text - MIT Libraries
S Benkhelifa, S Provot, E Nabais, A Eychene, G … - Mol. Cell. Biol, 2001 - mcb.asm.org
... and pointed P2 proteins of the Ets family (5) are phosphorylated by ERKs, c-Jun
(21) and ATF2 (16) are phosphorylated by JNKs, and CHOP (63), Pax6 (41), and ...
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Molecular Cell Biology of Brain Development
T Inoue - media.wiley.com
... Dorsal Ventral N FP (a) pD p0 p1 p2 p3 pMN from FP&N Nkx2.2/2.9 Nkx6.1 Nkx6.2 Pax6
Pax7 Irx3 Dbx2 Dbx1 Repressed by Shh Induced by Shh Olig2 Shh (b) ...
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Thyroid development and its disorders: genetics and molecular mechanisms - Full text - MIT Libraries
M De Felice, R Di Lauro - Endocr Rev, 2004 - edrv.endojournals.org
... In particular, Hoxa3 is detected in the floor of the pharynx, in the developing
thyroid (133, 134), and in the mesenchymal, endodermal, and neural crest ...
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A single morphogenetic field gives rise to two retina primordia under the influence of the … - Full text - MIT Libraries
H Li, C Tierney, L Wen, JY Wu, Y Rao - Development, 1997 - dev.biologists.org
Page 1. INTRODUCTION Formation of bilaterally symmetric and asymmetric structures
have been studied in vertebrates since the beginning ...
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Neuronal defects in the hindbrain of Hoxa 1, Hoxb 1 and Hoxb 2 mutants reflect regulatory … - Full text - MIT Libraries
A Gavalas, C Ruhrberg, J Livet, CE Henderson, R … - Development, 2003 - dev.biologists.org
Page 1. 5663 Introduction The vertebrate nervous system contains a vast
number of diverse neuronal cell types that serve distinct ...
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Hox Genes and Their Candidate Downstream Targets in the Developing Central Nervous System
ZN Akin, AJ Nazarali - springerlink.com
... function to replace the activity of another member of that same group that has been
disrupted (Horan et al., 1995a,b). As an example, Hoxa3, Hoxb3, and Hoxd3 ...
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About face: signals and genes controlling jaw patterning and identity in vertebrates
JM Richman, SH Lee - bone - doi.wiley.com
Page 1. About face: signals and genes controlling jaw patterning and identity
in vertebrates Joy M. Richman 1 * and Sang-Hwy Lee 2 ...
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Phylogenomic analysis and expression patterns of large Maf genes in Xenopus tropicalis provide new … - Full text - MIT Libraries
AMFBS Retaux, MP Felder-Schmittbuhl, SMJL … - Dev Genes Evol, 2005 - springerlink.com
Page 1. Dev Genes Evol (2005) 215: 327–339 DOI 10.1007/s00427-005-0476-y ORIGINAL
ARTICLE M. Coolen . K. Sii-Felice . O. Bronchain . A. Mazabraud . ...
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