PAX2 is expressed in multiple spinal cord interneurons, including a population of EN1 interneurons … - Full text - MIT Libraries
JD Burrill, L Moran, MD Goulding, H Saueressig - Development, 1997 - dev.biologists.org
... In addition, PAX2 does not colocalize with two proteins, PAX6 and PAX7, that are ...
A RCASBP(A) retrovirus that expresses a tau-myc reporter protein was generated ...
Cited by 72 - Web Search - dev.biologists.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov

Dominant-negative form of the Pax6 homolog eyeless for tissue-specific loss-of-function studies in … - Full text - MIT Libraries
T Niimi, J Clements, WJ Gehring, P Callaerts - Genesis, 2002 - doi.wiley.com
... The Drosophila Pax6 homolog eyeless has essential roles in the development of the
eye and ... Repression Do- main (amino acids 2–298) tagged with Myc tag (shaded ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic … - Full text - MIT Libraries
BC Lewis, DS Klimstra, HE Varmus - Genes & Development, 2003 - genesdev.org
... islets respectively (Table 2). Further, Pdx1 and the endocrine-specific transcription
factors Isl1, Nkx2.2, and Pax6 were detected in the c-Myc-induced tumors ...
Cited by 3 - Web Search - genesdev.org - dx.doi.org - ncbi.nlm.nih.gov - all 9 versions »

c-Myc Controls Proliferation Versus Differentiation in Human Pancreatic Endocrine Cells - Full text - MIT Libraries
C Demeterco, P Itkin-Ansari, B Tyrberg, LP Ford, … - J Clin Endocrinol Metab, 2002 - jcem.endojournals.org
... 7A ). Moreover, c-Myc activation did not result in a change in the level of mRNA
for Pax6 or in the induction of BETA2/NeuroD1 gene expression that occurs when ...
Cited by 5 - Web Search - jcem.endojournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Headless flies produced by mutations in the paralogous Pax6 genes eyeless and twin of eyeless - Full text - MIT Libraries
J Kronhamn, E Frei, M Daube, R Jiao, Y Shi, M Noll … - Development, 2002 - dev.biologists.org
... 8 mutation generates headless flies Both Drosophila homologs of the vertebrate Pax6
gene, ey ... by P35 expression, but only by overexpression of Ey, CycE or Myc. ...
Cited by 12 - Web Search - molbio.unizh.ch - unizh.ch - ncbi.nlm.nih.gov - all 5 versions »

A comparative cDNA microarray analysis reveals a spectrum of genes regulated by Pax6 in mouse lens - Full text - MIT Libraries
MK Duncan, A Cvekl - Genes to Cells, 2002 - ingentaconnect.com
... down-regulated in Pax6(con) lenses Gene Description GenBank accession no. Fold change
Cell growth, division and DNA synthesis Ndr1 N-myc downstream regulated 1 ...
Cited by 12 - Web Search - genestocellsonline.org - ijp-online.com - ncbi.nlm.nih.gov - all 6 versions »

Charakterisierung eines neuen Proteins, Mapl-1 und seine Rolle in der Regulation der Pax6-Funktion
P Petrou - deposit.ddb.de
... Rolle in der Regulation der Pax6-Funktion ... 2.1 Mapl-1 als
potentieller Pax6-Interaktionspartner.....17 ...
Web Search - webdoc.sub.gwdg.de - webdoc.gwdg.de

The PAX6 gene is activated by the basic helix–loop–helix transcription factor NeuroD/BETA2 - Full text - MIT Libraries
E Marsich, A Vetere, M Di Piazza, G Tell, S … - Biochem J, 2003 - bj.portlandpress.com
... 707 The PAX6 gene is activated by the basic helix–loop–helix transcription ... The role
of the PAX6 gene in the development of the pancreas has been analysed. ...
Cited by 4 - View as HTML - Web Search - biochemj.org - biochemj.org - ncbi.nlm.nih.gov - all 5 versions »

Regionally restricted expression of the transcription factor c-myc intron 1 binding protein during … - Full text - MIT Libraries
DB Campbell, P Levitt - The Journal of Comparative Neurology, 2003 - doi.wiley.com
... Distinct actions of Emx1, Emx2, and Pax6 in regulating the specification of areas ...
of the biological functions of a transcription factor, c-myc intron binding ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

SOX2 functions to maintain neural progenitor identity - Full text - MIT Libraries
V Graham, J Khudyakov, P Ellis, L Pevny, N Center - Neuron, 2003 - healthsystem.virginia.edu
... By HH18–19, SOX2ER myc , Pax6 expression is downregulated (Figures the
cells that incorporated BrDU were mutually exclusive 6O ...
Cited by 39 - View as HTML - Web Search - bio.unc.edu - ingentaconnect.com - all 6 versions »

The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes … - Full text - MIT Libraries
M Dottori, MK Gross, P Labosky, M Goulding - Development, 2001 - dev.biologists.org
... Pax6 expression was examined in Foxd3 Myc -electroporated neural tubes to test whether
Foxd3 suppresses the early developmental program of interneuron ...
Cited by 33 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Math3 and NeuroD regulate amacrine cell fate specification in the retina - Full text - MIT Libraries
T Inoue, M Hojo, Y Bessho, Y Tano, JE Lee, R … - Development, 2002 - dev.biologists.org
... (A) Retroviral vectors. The bHLH genes (Math3, NeuroD and Mash1) were fused
with GFP, and Pax6 has three repeats of Myc tag. (BE ...
Cited by 37 - Web Search - ncbi.nlm.nih.gov

Potential for neural regeneration after neurotoxic injury in the adult mammalian retina
S Ooto, T Akagi, R Kageyama, J Akita, M Mandai, Y … - Proceedings of the National Academy of Sciences - pnas.org
... cells. (A) Structures of the recombinant retrovirus. The bHLH genes were
fused with GFP, and Pax6 has three repeats of Myc tag. (B ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - zobell.biol.tsukuba.ac.jp - dx.doi.org - all 7 versions » - Get it from MIT Libraries

Acetylation of the BETA2 transcription factor by PCAF is important in Insulin gene expression
NIH NCI, NIH NIDDK - jbc.org
... IP anti-AK IP IgG TL MIN6 PAX6 WB: anti-PAX6 HIT Figure 1 Page 25. WB: anti-Myc
BETA2 +PCAF BETA2 +PCAF ∆ HAT BETA2 BETA2 +PCAF BETA2 +PCAF ∆ HAT BETA2 ...
Cited by 1 - Web Search - jbc.org

Phosphorylation of Pax 2 by the c-Jun N-terminal Kinase and Enhanced Pax 2-dependent Transcription … - Full text - MIT Libraries
Y Cai, MS Lechner, D Nihalani, MJ Prindle, LB … - J Biol Chem, 2002 - jbc.org
... is a substrate for the c-Jun N-terminal kinase (JNK) but, unlike Pax6, is not ... as
described (3). The CMV-MEKK1 wild-type, CMV-MEKK1 K432M, HA-DLK, Myc-Erk, FLAG ...
Cited by 10 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Comparative FISH-mapping in river buffalo and sheep chromosomes: assignment of forty autosomal type …
L Iannuzzi, GP Di Meo, A Perucatti, L Schibler, D … - Cytogenet Cell Genet, 2001 - content.karger.com
... Note that while MYC and CGA map on homoeologous chromosomes (BBU15/OAR9 and
BBU10/OAR8 ... Loci mapping in OAR15 and BBU16 (MMP1, FDX1, APOA1, PAX6 and WT1) map ...
Cited by 10 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Subject Index to Volume 43
DG Differ - ingentaconnect.com
... ondansetron 5-HT in ascidian development 647 oogenesis c-myc RNA stability ... 295
Patiriella evolution of larval form in sea stars 459 Pax6 efficient transfection ...
Web Search - ingentaconnect.com

Wnt 2 b controls retinal cell differentiation at the ciliary marginal zone - Full text - MIT Libraries
F Kubo, M Takeichi, S Nakagawa - Development, 2003 - dev.biologists.org
... of the retinal progenitor cells are identified by co-expression of Pax6 and Chx10 ...
The construction of pcDNA3.1-mFzd4-CRD-myc and hFzd5-CRD-myc was described ...
Cited by 20 - Web Search - dx.doi.org - dev.biologists.org - ncbi.nlm.nih.gov

GP0334 TRANSCRIPTION FACTORS
POFT FACTOR, GELSA EMSA, GELSA EMSA - kcl.ac.uk
... 2;8) or t(8;22) cMyc > IGL κ or λ genes C-Myc under transcriptional ... tumour suppressor,
deletion in Wilm’s tumour and genitourinary defects Pax6 deleted in ...
View as HTML - Web Search

The Basic Helix-Loop-Helix Leucine Zipper Transcription Factor Mitf Is Conserved in Drosophila and … - Full text - MIT Libraries
JH Hallsson, BS Haflidadottir, C Stivers, W … - Genetics, 2004 - genetics.org
... The MITF protein is a member of the MYC family of basic ... RPE cells hyperproliferate,
abnormally express the retinal transcriptional regulator Pax6, and form an ...
Cited by 2 - Web Search - genetics.org - ncbi.nlm.nih.gov

In ovo electroporation of Crim1 in the developing chick spinal cord. - Full text - MIT Libraries
G Kolle, A Jansen, T Yamada, M Little - DEVELOPMENTAL DYNAMICS, 2003 - doi.wiley.com
... markers when electroporated with CRIM1-E myc but not CRIM1-N myc or GFP. ... Pax6 con-
trols progenitor cell identity and neuro- nal fate in response to graded Shh ...
Web Search - ncbi.nlm.nih.gov

A LINE element is present at the site of a 300-kb deletion starting in intron 10 of the PAX 6 gene … - Full text - MIT Libraries
M Drechsler, B Royer-Pokora - Human Genetics, 1996 - springerlink.com
... Pearce WG, MacDonald IM, Walter MA (1995) Mu- tation of the PAX6 gene in ... South VJ,
Spandorfer JM, Astrin SM (1988) Insertional mutagenesis of the myc locus by ...
Cited by 21 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

PTIP, a novel BRCT domain-containing protein interacts with Pax 2 and is associated with active … - Full text - MIT Libraries
MS Lechner, I Levitan, GR Dressler - Nucleic Acids Research, 2000 - nar.oupjournals.org
... The portions of Pax2 (or Pax6 and Pax8) encoded by the ... antibody 12CA5 (Boehringer
Mannheim Biochemical, Indianapolis, IN), anti-myc monoclonal antibody 9E10 ...
Cited by 13 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Specific Pax-6/Microphthalmia Transcription Factor Interactions Involve Their DNA-binding Domains … - Full text - MIT Libraries
N Planque, L Leconte, FM Coquelle, P Martin, S … - J Biol Chem, 2001 - jbc.org
... from pEGFP-1, CLONTECH) was ligated to an EcoRV-SphI Klenow-treated v-Myc fragment
(from MC29 ... 1. Both the Pax6 paired domain and homeodomain interact with Mitf. ...
Cited by 14 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov

Eya protein phosphatase activity regulates Six 1–Dach–Eya transcriptional effects in mammalian … - Full text - MIT Libraries
X Li, KA Oghi, J Zhang, A Krones, KT Bush, CK … - Nature, 2003 - nature.com
... RL Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression ...
Tessarollo, L., Sassoon, DA & Parada, LF Loss of N-myc function results ...
Cited by 50 - Web Search - 130.15.90.245 - biochem.med.umich.edu - 138.26.45.18 - all 8 versions »

Sox21 promotes the progression of vertebrate neurogenesis - Full text - MIT Libraries
M Sandberg, M Kaellstroem, J Muhr - Nature Neuroscience, 2005 - nature.com
... 3a) were maintained in a proliferative and Pax6 + progenitor state and failed to
upregulate ... of Sox3 (blue) and Sox21 (yellow) were fused to a myc-epitope tag ...
Web Search - nature.com

Transcriptional regulation of the human PAX 6 gene promoter. - Full text - MIT Libraries
ZP Xu, GF Saunders - J Biol Chem, 1997 - jbc.org
... a pyrimidine-rich initiator element, is also found at the PAX6 transcriptional start
site ... binding sites for Sp1 protein (at bases 395 to 387), Myc protein (at ...
Cited by 13 - Web Search - jbc.org - ncbi.nlm.nih.gov

Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9
P Stapleton, A Weith, P Urbanek, Z Kozmik, M … - Nature Genetics, 1993 - nature.com
... RL Genomic Structure, evolutionary conservation and aniridia mutations in the human
PAX6 gene ... exclusive expression of a helix-loop-helix gene and N-myc in human ...
Cited by 42 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Evx1 is a postmitotic determinant of v0 interneuron identity in the spinal cord - Full text - MIT Libraries
L Moran-Rivard, T Kagawa, H Saueressig, MK Gross, … - Neuron, 2001 - chalk.salk.edu
... Generation of Conditional Evx1 tau-myc Knockin Mice ... Section through E10.5 mouse spinal
cord showing Evx1 (red) is not expressed in divid- ing Pax6 cells (green ...
Cited by 52 - View as HTML - Web Search - ncbi.nlm.nih.gov

Roles of homeobox and bHLH genes in specification of a retinal cell type - Full text - MIT Libraries
J Hatakeyama, K Tomita, T Inoue, R Kageyama - Development, 2001 - dev.biologists.org
... (A) Schematic structure of retroviral vectors. Three repeats of the Myc
epitope were fused at the N terminus of Chx10 and Pax6. ...
Cited by 50 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell … - Full text - MIT Libraries
BR Gauthier, TBCB Wollheim, EJ Schoenle - Diabetologia, 2005 - springerlink.com
... derm-derived endocrine pancreas is mediated through Pax4 and Pax6 [6]. Inactivation ...
effect of several signal transduction pathways towards the Myc-Id2 cascade. ...
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Paired-Type Homeodomain Transcription Factors Are Imported into the Nucleus by Karyopherin 13 - Full text - MIT Libraries
JE Ploski, MK Shamsher, A Radu - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... lysates (columns 1 and 2). No signal for Myc-Kap13 or GFP-Pax6 was detected in cells
that were not transfected with the respective plasmids (data not shown). ...
Cited by 2 - Web Search - dx.doi.org - mcb.asm.org - ncbi.nlm.nih.gov

Pax-Q/W/Pax-6, - Full text - MIT Libraries
HC Gene - Molecular Endocrinology, 1994 - mend.endojournals.org
... quail neuroretina cells infected with the v-myc containing avian retrovirus MC29,
we have isolated a cDNA clone Pax-QNR, homologous to the murine Pax6 which is ...
Web Search

Pax-QNR/Pax-6, a paired box-and homeobox-containing gene expressed in neurons, is also expressed in … - Full text - MIT Libraries
N Turque, S Plaza, F Radvanyi, C Carriere, S Saule - Mol. Endocrinol, 1994 - mend.endojournals.org
... quail neuroretina cells infected with the v-myc containing avian retrovirus MC29,
we have isolated a cDNA clone Pax-QNR, homologous to the murine Pax6 which is ...
Cited by 52 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Meis family proteins are required for hindbrain development in the zebrafish - Full text - MIT Libraries
SK Choe, N Vlachakis, CG Sagerstrom - Development, 2002 - dev.biologists.org
... B), MycMeis3 (C) or CPbx4 +MycMeis3 (D), raised to 12 hpf and stained with
anti-Myc antibody. ... Black triangle in R indicates region of strong pax6 expression. ...
Cited by 12 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

DE L’APPAREIL URINAIRE ET DYSPLASIES KYSTIQUES DES REINS
C Dareste - urofrance.org
... Gènes: Pax8 EYA1 Bcl2, L-MYC AP2-béta ... Dans le syn- drome WAGR, la délétion de la
bande 11p13 inté- resse plusieurs gènes comprenant les gènes PAX6 et WT1 ...
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Radial glial identity is promoted by Notch1 signaling in the murine forebrain - Full text - MIT Libraries
N Gaiano, JS Nye, G Fishell - Neuron, 2000 - saturn.med.nyu.edu
... with dotted lines) spans residues 1753–2185, and has a Myc tag at ... glia express
regionally restricted markers such as Pax6 dorsally (Gotz et al., 1998) and ...
Cited by 145 - View as HTML - Web Search - predator.pnb.uconn.edu - biology.ucsc.edu - all 8 versions »

Translocation breakpoints in three patients with campomelic dysplasia and autosomal sex reversal map … - Full text - MIT Libraries
J Wirth, T Wagner, J Meyer, RA Pfeiffer, HU Tietze … - Hum. Genet, 1996 - springerlink.com
... Burkitt lym- phoma cells with chromosomal t(8;14) translocation separate c- myc
and the ... Sea- wright A, Hastie N, Heyningen V van (1992) The human PAX6 gene is ...
Cited by 38 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Position effect in human genetic disease - Full text - MIT Libraries
D Kleinjan, V van Heyningen - Human Molecular Genetics, 1998 - dx.doi.org
... For instance, in Burkitt's lymphoma a translocation places the c-MYC gene under
the ... The PAX6 gene was one of the first to provide a compelling argument that ...
Cited by 118 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Diabetes and pancreatic tumours in transgenic mice expressing Pa × 6 - Full text - MIT Libraries
T Yamaoka, M Yano, T Yamada, T Matsushita, M … - Diabetologia, 2000 - springerlink.com
... Littermate Insulin/ Pax6-Tg PDX/ Pax6-Tg ... Similar phenomena were observed in the
transgenic overexpression of c-myc [28±30] and E2F-1 [31±33]. ...
Cited by 12 - Web Search - ncbi.nlm.nih.gov

Essential role of NAT 1/p 97/DAP 5 in embryonic differentiation and the retinoic acid pathway - Full text - MIT Libraries
S Yamanaka, XY Zhang, M Maeda, K Miura, S Wang, RV … - The EMBO Journal, 2000 - embojournal.npgjournals.com
... for cap-independent translation initiation mediated by the IRES of EMCV, c-myc and
NAT1 ... for 5 days (Figure 7B). In addition, the expression of pax6, a marker ...
Cited by 15 - Web Search - emboj.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

EMBRYONIC SUBMANDIBULAR SALIVARY GLAND DEVELOPMENT
PB Stage, P Stage - usc.edu
... in Pax6 and Bmp7 null mice (Table 2) indicates that Pax6 and Bmp7are ... a5 are not
essential for SMG morphogenesis (Table 2). Finally, since N-myc null mutations ...
View as HTML - Web Search

Subunits of the Heterotrimeric Transcription Factor NF-Y Are Imported into the Nucleus by Distinct …
J Kahle, M Baake, D Doenecke, W Albig - mcb.asm.org
... The paired-type homeodomain transcription factors Pax6, Pax3, and Crx (56), the
SUMO-1/sentrin ... the EcoRI-StuI sites of pCS2+MT (65, 75) containing 6 myc tags at ...
Web Search - mcb.asm.org

Sex reversal by loss of the C–terminal transactivation domain of human SOX 9
P Suedbeck, ML Schmitz, PA Baeuerle, G Scherer - Nature Genetics, 1996 - nature.com
... PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia
and central ... HM et al.Mutations in the coding region of c-myc in AIDS ...
Cited by 87 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

BSAP(Pax 5)-Importin alpha 1(Rch 1) Interaction Identifies a Nuclear Localization Sequence - Full text - MIT Libraries
CR Kovac, A Emelyanov, M Singh, N Ashouian, BK … - J Biol Chem, 2000 - jbc.org
... 4), including CD19, LEF, N-myc, mb-1, and PD1, although these are unlikely to ... domain
and central domain segments of other Pax proteins, ie quail Pax6 (25) and ...
Cited by 8 - Web Search - cellbio.aecom.yu.edu - aecom.yu.edu - ncbi.nlm.nih.gov - all 6 versions »

CNR/Pcdh alpha family in subplate neurons, and developing cortical connectivity - Full text - MIT Libraries
H Morishita, Y Murata, S Esumi, S Hamada, T Yagi - Neuroreport, 2004 - neuroreport.com
... Sigma), anti-neurofilament (2H3, Developmental Studies Hybridoma Bank), anti-c-myc
sc-40 ... L, Lopez-Bendito G, Gruss P, Stoykova A and Molnar Z. Pax6 is required ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Long-depth imaging of specific gene expressions in whole-mount mouse embryos with single-photon … - Full text - MIT Libraries
C Palmes-Saloma, C Saloma - J. Struct. Biol, 2000 - ncbi.nlm.nih.gov
... Gene Expression; Gene Expression Profiling*; Genes, myc/genetics; Homeodomain Proteins*; ...
PAX6 protein; RNA Probes; RNA, Messenger; Digoxigenin; Fluorescein-5 ...
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Wnt and Bmp signalling cooperatively regulate graded Emx2 expression in the dorsal telencephalon - Full text - MIT Libraries
T Theil, S Aydin, S Koch, L Grotewold, U Ruther - Development, 2002 - dev.biologists.org
... Given the significance of graded Emx2 and Pax6 expression for the generation of ... for
a fresh aliquot containing the primary antibody [anti-Myc (mouse monoclonal ...
Cited by 25 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Gordon C. Weir, David Ross Laybutt, Hideaki Kaneto, Susan Bonner-Weir, and Arun Sharma - Full text - MIT Libraries
FHPOF DETERIORATION - DIABETES, 2001 - diabetes.diabetesjournals.org
... PDX-1, HNFs, Nkx6.1, and Pax6) Increased gene expression of LDH, hexokinase, glucose-
6-phosphatase, and the transcription factor c-Myc Decompensation: severe ...
Web Search

Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene - Full text - MIT Libraries
Z Kozmik, P Pfeffer, J Kralova, J Paces, V Paces, … - Development Genes and Evolution, 1999 - springerlink.com
... mice will shed more light into the possible regulatory role of Pax6 in Dach ... deletion
of the short arm of chromosome 1, amplification of the N-myc proto-oncogene ...
Cited by 28 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov