Regulation of eye formation by the Rx and pax6 homeobox genes - Full text - MIT Libraries
PH Mathers, M Jamrich - Cell. Mol. Life Sci, 2000 - springerlink.com
... Ocular formation by Rx and pax6 ... In addition, the intricate autoregulatory and
cross-regulatory rela- tionships among these factors compound the complex- ity ...
Cited by 21 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

PAX6 gene mutations and genotype-phenotype correlations in sporadic cases of aniridia from India …
ABM Reddy, VS Kiran, AK Mandal, SG Panicker, S … - Ophthalmic Genetics, 2003 - taylorandfrancis.metapress.com
... AG3 proband except that he did not present with mild corneal dystrophy (Table 1).
The frequency of the PAX6 mutation in the present study was rela- tively low ...
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Ultramicroscopical immunolocalization of PAX6 in the adult chicken retina.
DH Shin, BS Kwon, YP Chang, S Bae, J Kim, JW Kim - acta histochemica, 2003 - ingentaconnect.com
... Hwang DH, and Chang KY (1998) Localization of transferrin binding protein in rela-
tion to ... M, Nomura T, and Fuji- sawa H (1997) Distributions of PAX6 and PAX7 ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Dlx1, Dlx2, Pax6, Brn3b, and Chx10 Homeobox Gene Expression Defines the Retinal Ganglion and Inner … - Full text - MIT Libraries
DD EISENSTAT - THE JOURNAL OF COMPARATIVE NEUROLOGY, 2003 - doi.wiley.com
... 1:4,000, courtesy of Thomas Jessell, Columbia University); mouse monoclonal to Pax6
(1:150, A ... The rela- tive increase reflects the increasing size of the eye at ...
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Expression of Regulatory Homeobox Genes during Retina Regeneration in Adult Newts
EO Makar’ev, RD Zinov’eva, VI Mitashov - BIOLOGY BULLETIN, 2002 - kluweronline.com
... The rela- tionship of PCR products to the above genes was confirmed by sequencing.
A comparative PCR analysis of expression of Pax6, Prox1, and Six3 was ...
Cited by 2 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Patterning defects in the primary axonal scaffolds caused by the mutations of the extradenticle and … - Full text - MIT Libraries
T Nagao, K Endo, H Kawauchi, U Walldorf, K … - Development Genes and Evolution, 2000 - springerlink.com
... In ad- dition, expression of a Drosophila Pax6 gene, eyeless, is significantly ... molecular
mechanisms of brain patterning can be reduced to rela- tively simple ...
Cited by 6 - Web Search - uniklinik-saarland.de - med-rz.uni-sb.de - biol.tsukuba.ac.jp - all 7 versions »

Origin of the paired domain - Full text - MIT Libraries
R Breitling, JK Gerber - Development Genes and Evolution, 2000 - springerlink.com
... 3D-structure comparison, and phylogenetic reconstruction, we analyzed the rela-
tionship between ... Pax1–9/meso, PaxD/3–7/paired/gooseberry, Pax6–4/ eyeless ...
Cited by 8 - Web Search - brc.dcs.gla.ac.uk - ncbi.nlm.nih.gov

Dana J. Philpott* and Michelle Rathman
K Vousden - doi.wiley.com
... This meeting focused on ‘‘cellular microbiology,’’ a rela- tively new scientific ...
peripheral part of the CMZ, several genes, including Pax6 and Six3 are ...
Web Search - doi.wiley.com

Factors affecting the timing and imprinting of replication on a mammalian chromosome - Full text - MIT Libraries
WA Bickmore, AD Carothers - J Cell Sci, 1995 - jcs.biologists.org
... c1-11- 464 (D11S676), c1-11-458 (D11S458), c20/18 (D11S377), cH11148 (D11S2134),
cB2.1 (WT1), cp60 (D11S324), cA08102 (D11S323) cFAT5 (PAX6), cA04160 (D11S317 ...
Cited by 38 - Web Search - jcs.biologists.org - ncbi.nlm.nih.gov

Specification of neuronal fates in the ventral neural tube - Full text - MIT Libraries
J Briscoe, J Ericson - Curr. Opin. Neurobiol, 2001 - retinotectal.med.umn.edu
... as the related protein Nkx2.9, is sufficient to repress Pax6 expression in ... in mutually
exclusive progenitor domains and a cross-repressive rela- tionship is ...
Cited by 93 - View as HTML - Web Search - healthsystem.virginia.edu - neurobio.arizona.edu - all 5 versions »

Molecular aspects of vertebrate retinal development
SS Zhang, XY Fu, CJ Barnstable - Mol. Neurobiol, 2002 - biomed.humanapress.com
... It is accessible, and its rela- tively simple laminated structure with few ... serve
essential roles in this event have been well documented, such as Pax6, Rx, Six3 ...
Cited by 9 - Web Search - neurosci.humanapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Inductive interactions direct early regionalization of the mouse forebrain - Full text - MIT Libraries
K Shimamura, JL Rubenstein - Development, 1997 - dev.biologists.org
... Pax6 expression is reduced around the site of the transplantation (compare level ...
This temporal rela- tionship strongly suggests that FGF8 produced from the ANR ...
Cited by 207 - Web Search - dev.biologists.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov

Generation of structures formed by lens and retinal cells differentiating from embryonic stem cells - Full text - MIT Libraries
M Hirano, A Yamamoto, N Yoshimura, T Tokunaga, T … - Developmental Dynamics, 2003 - doi.wiley.com
... To test more precisely the rela- tionship between gene expression and morphology
of the eye ... ES cell lines established from the em- bryos of a Pax6 mutant (Pax6 ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene - Full text - MIT Libraries
Z Kozmik, P Pfeffer, J Kralova, J Paces, V Paces, … - Development Genes and Evolution, 1999 - springerlink.com
... Pax6 is a vertebrate homologue of ey (Callaerts et al. ... This rela- tionship, in addition
to the available data on Drosophila dac, provide first hints about the ...
Cited by 28 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Molecular Mapping of the Origin of Postnatal Spinal Cord Ependymal Cells: Evidence That Adult … - Full text - MIT Libraries
H FU, Y QI, M TAN, J CAI, X HU, Z LIU, J JENSEN, M … - THE JOURNAL OF COMPARATIVE NEUROLOGY, 2003 - doi.wiley.com
... and E4 (E–H) chicken embryos were immunolabeled by antibodies against Pax7 (A,E),
Pax6 (B,F), Nkx6.1 (C,G), and Nkx2.2 (D,H). The spatial rela- tionship of ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

THE SINGLE STRAND CONFORMATIONAL ANALYSIS OF CATTLE AND HUMAN SINGLE NUCLEOTIDE POLYMORPHISMS MAY BE …
SOFSS DNA - ANIMAL BIOTECHNOLOGY, 2001 - taylorandfrancis.metapress.com
... se- quences have low self-complementarity while mononucleotide repeats are rela-
tively rare, have low ... PAX6 mis- sense mutation in isolated foveal hypoplasia. ...
Web Search - ncbi.nlm.nih.gov - csa.com - Get it from MIT Libraries

Identification of a Proliferating Marginal Zone of Retinal Progenitors in Postnatal Chickens - Full text - MIT Libraries
AJ Fischer, TA Reh - Dev Biol, 2000 - faculty.washington.edu
... the chicken eye; (ii) cells at the retinal margin coexpress Pax6, Chx-10 ... Since this
cell type is formed rela- tively early during embryonic development (Prada ...
Cited by 59 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Lens epithelial proliferation cataract in segmental trisomy involving mouse Chromosomes 4 and 17 - Full text - MIT Libraries
RS Smith, KR Johnson, NL Hawes, BS Harris, JP … - Mammalian Genome, 1999 - springerlink.com
... In mice, loss of the Pax6 gene is responsible for the small-eye ... However, lens epithelium
is rela- tively undifferentiated and has the capacity to undergo ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Oligodendrocyte lineage and the motor neuron connection - Full text - MIT Libraries
WD Richardson, HK Smith, T Sun, NP Pringle, A Hall … - Glia, 2000 - doi.wiley.com
... that generates sMNs; that is, to the lower part of the pax6 gradient, outside ... we
now know that OLPs are highly mobile cells that can migrate rela- tively long ...
Cited by 59 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Specification du domaine endodermique du pancreas
EE Canal, M Ectoderme - MEDECINE/SCIENCES, 2002 - ist.inserm.fr
... Les facteurs de transcription à homéodomaine Pax6, Nkx2.2, Nkx6.1, Isl1 ... sous- types
de neurones et, dans une certaine mesure, leurs rela- tions épistatiques ...
View as HTML - Web Search - disc.vjf.inserm.fr

Pax2 mutant mice display increased number and size of islets of Langerhans but no change in insulin … - Full text - MIT Libraries
M Zaiko, A Estreicher, B Ritz-Laser, P Herrera, J … - European Journal of Endocrinology, 2004 - eje.org
... Alternatively, the rela- tively mild pancreatic phenotype of Pax2 1Neu mice ... Pax2
and Pax6 expression has been shown to be inter- dependent in eye development ...
View as HTML - Web Search - eje-online.org - eje.org - ncbi.nlm.nih.gov - all 5 versions »

Neurofibromin Deficiency in Mice Causes Exencephaly and Is a Modifier for Splotch Neural Tube … - Full text - MIT Libraries
M Lakkis, JA Golden, KS O’Shea, JA Epstein - Developmental Biology, 1999 - uphs.upenn.edu
... expressed in multiple embryonic tissues, including rela- tively high levels in the
developing ... Nf1 mutants led us to test for expression of the Pax6 gene, which ...
Cited by 13 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Tissue interactions and lens-forming competence in the outer cornea of larvalXenopus laevis - Full text - MIT Libraries
SM Cannata, E Arresta, S Bernardini, C Gargioli, S … - Journal of Experimental Zoology, 2003 - doi.wiley.com
... The regeneration potential and the lens-forming transformations of the implants
were tested using an antisense probe for pax6 as an earlier marker of lens ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Eyes: Variety, Development and Evolution - Full text - MIT Libraries
RD Fernald - Brain Behavior and Evolution, 2004 - content.karger.com
... OTX1, orthodenticle homologue 1; PAX2, paired box gene 2; pax6, paired domain ... Similarly,
a comparison of rela- tive sensitivities among vertebrates reveals a ...
Web Search - stanford.edu - gurdon.cam.ac.uk - ncbi.nlm.nih.gov - all 5 versions »

AVANCES EN LA GENETICA DE LOS GLAUCOMAS
EO Gonzalez, MM Rodriguez, AOG Garcia, AL Cruz - sld.cu
... describiera su pro- pia ceguera y la de su hermano con rela- ción a ... 32 Un gen candidato,
clonado en seres humanos, y nombrado PAX6 (Paired Box Homeotic Gene-6 ...
Cited by 1 - View as HTML - Web Search - bvs.sld.cu - infomed.sld.cu

Evolution of eyes - Full text - MIT Libraries
RD Fernald - Curr. Opin. Neurobiol, 2000 - stanford.edu
... The evolution of lenses depended on generating a rela- tively large amount of ... X,
Heaney S, Yoon A, Michelson AM, Maas RL: Regulation of Pax6 expression is ...
Cited by 27 - View as HTML - Web Search - euplotes.biology.uiowa.edu - med.nyu.edu - ncbi.nlm.nih.gov - all 5 versions »

Development of the limb neuromuscular system
K Sharma, JC Belmonte - Curr. Opin. Cell Biol, 2001 - cbi.pku.edu.cn
... a motor neuron fate through the action of Shh that induces Pax6 expression in a ... for
example, bones and tendons) provide the static infrastructure rela- tive to ...
Cited by 4 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Dominance and Homozygosity - Full text - MIT Libraries
MCALOF FUNCTION - American Journal of Medical Genetics, 1997 - doi.wiley.com
... compound heterozygote for the two dif- ferent missense mutations in PAX6 [Glaser
et ... frequency among the Libyan Jews, a community that was rela- tively isolated ...
Web Search - doi.wiley.com

Outpatient clinic for genetic counseling and gene testing of retinoblastoma - Full text - MIT Libraries
K Sugano, T Yoshida, H Izumi, S Umezawa, M Ushiama … - Int J Clin Oncol, 2004 - springerlink.com
... 5 In such a couple, the risk of a heterozygous mutation of the RB1 gene and/or the
Pax6 gene in their Fig. 1. Recurrence risk for rela- tives of patients with ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Debatable homologies - Full text - MIT Libraries
D Tautz - Nature, 1998 - nature.com
... finding that highly conserved ‘master regula- tor’ genes such as Pax6/eyeless are ...
the forces can be balanced by shifting the middle particle rela- tive to ...
Cited by 12 - Web Search - nature.com - ncbi.nlm.nih.gov

Mutations affecting the development of the embryonic zebrafish brain - Full text - MIT Libraries
AF Schier, SC Neuhauss, M Harvey, J Malicki, L … - Development, 1996 - dev.biologists.org
... The following probes have been used: krox-20 (Oxtoby and Jowett, 1993); pax[zf-b]
(Krauss et al., 1991a; Püschel et al., 1992b); pax6 (Krauss et al., 1991b,c ...
Cited by 133 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Use of the Japanese Pufferfish(Fugu rubripes) in Comparative Genomics - Full text - MIT Libraries
MS Clark, SF Smith, G Elgar - Marine Biotechnology - springerlink.com
... Figure 2. CLUSTAL W alignment of upstream regions of the PAX6 gene in ... While the gene
complement of the MHC remains rela- tively stable, rearrangements have ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Growth factor-responsive progenitors in the postnatal mammalian retina - Full text - MIT Libraries
X Zhao, AV Das, F Soto-Leon, I Ahmad - Developmental Dynamics, 2005 - doi.wiley.com
... progenitor marker, nestin, and the retinal pro- genitor markers, Pax6 and Chx10 ...
BrdU-positive cells express- ing differentiation markers were rela- tively more ...
Web Search - ncbi.nlm.nih.gov

MuStaR™ and other software for locus-specific mutation databases - Full text - MIT Libraries
AF Brown, MA McKie - Human Mutation, 2000 - doi.wiley.com
... derived from the soft- ware developed for the Human PAX6 Mutation Database ... This
situation is avoided by using specialised rela- tional or object-oriented ...
Cited by 9 - Web Search - ncbi.nlm.nih.gov

A novel dysmorphic syndrome with open calvarial sutures and sutural cataracts maps to chromosome 14q … - Full text - MIT Libraries
SA Boyadjiev, CM Justice, W Eyaid, VA McKusick, RS … - Hum Genet, 2003 - springerlink.com
... FGF1, FGF2, and FGF8 are also documented regulators of PAX6 and have been ... However,
given the consanguineous rela- tionships, as defined in the pedigree (which ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Gordon C. Weir, David Ross Laybutt, Hideaki Kaneto, Susan Bonner-Weir, and Arun Sharma - Full text - MIT Libraries
FHPOF DETERIORATION - DIABETES, 2001 - diabetes.diabetesjournals.org
... metabolic enzymes were also downregulated, includ- ing PDX-1, Nkx6.1, Pax6, Beta2,
HNF1 ... it has been difficult to prove a cause-and-effect rela- tionship and to ...
Web Search

Ocular and cerebellar defects in zebrafish induced by overexpression of the LIM domains of the islet … - Full text - MIT Libraries
Y Kikuchi, H Segawa, M Tokumoto, T Tsubokawa, Y … - Neuron, 1997 - invivo.caltech.edu
... Zebrafish embryos are transparent and have a rela- Okazaki, Aichi 444 ... Pax6
mRNA was also expressed in the diencephalon al., 1994). ...
Cited by 23 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Raldh 2 expression in optic vesicle generates a retinoic acid signal needed for invagination of … - Full text - MIT Libraries
FA Mic, A Molotkov, N Molotkova, G Duester - Developmental Dynamics, 2004 - doi.wiley.com
... Loss of optic vesicle RA signaling does not effect expression of early determinants
of retina at the optic vesicle stage (Pax6, Six3, Rx, Mitf). ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Detecting Light
L RECEPTION - doi.wiley.com
Page 1. Chapter 14 Detecting Light Light is the ultimate resource for all
forms of life. Organisms use light in three basic ways, the ...
Web Search

Identification of ciliary epithelial-specific genes using subtractive libraries and cDNA arrays in … - Full text - MIT Libraries
R Kubota, C McGuire, B Dierks, TA Reh - Developmental Dynamics, 2004 - doi.wiley.com
... The up-regula- tion in pax6 expression is present as early as stage 21 ... By contrast,
the rela- tively low level of proliferation in the developing ciliary ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Arealization of the Neocortex in Mammals: Genetic and Epigenetic Contributions to the Phenotype - Full text - MIT Libraries
LKKJ Huffman - Brain Behav Evol, 2000 - content.karger.com
... Fig. 4. The graded distribution of regulatory genes Emx2 and Pax6 in the mouse ... but
we would also argue that these initial thalamocortical rela- tionships can ...
Web Search - content.karger.com

Were vertebrates octoploid - Full text - MIT Libraries
RF Furlong, PWH Holland - Philos Trans R Soc Lond B Biol Sci, 2002 - journals.royalsoc.ac.uk
... This indicates that 1 : 2, 1 : 3 and 1 : 4 ratios (fly : human or nematode : human)
are rela- tively common, although none of ... Pax6 b 1 1 1 to 1 Glardon et al. ...
Cited by 42 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

Markovian domain fingerprinting: statistical segmentation of protein sequences - Full text - MIT Libraries
G Bejerano, Y Seldin, H Margalit, N Tishby - Bioinformatics, 2001 - bioinformatics.oupjournals.org
... representative family member. This Pax6 SS protein contains both the paired and
homeobox domains. Both have matching signa- tures. This also ...
Cited by 8 - Web Search - cs.huji.ac.il - soe.ucsc.edu - ingentaconnect.com - all 8 versions »

Onset of Tlx-3 expression in the chick cerebellar cortex correlates with the morphological … - Full text - MIT Libraries
C LOGAN, C MILLAR, V BHARADIA, K ROULEAU - THE JOURNAL OF COMPARATIVE NEUROLOGY, 2002 - doi.wiley.com
... PAX6 protein was detected using a 1:200 dilution of the mouse monoclonal PAX6 antibody
developed by Dr. Atsushi Kawakami (obtained as supernatant from the ...
Web Search - ncbi.nlm.nih.gov

Insertions, substitutions, and the origin of microsatellites - Full text - MIT Libraries
Y ZHU, JE STRASSMANN, DC QUELLER - Genetical Research, 2000 - journals.cambridge.org
... 25 PAX6 TACTgaGATCCA Yes (1) Jordan et al. ... However, a rela- tively low percentage
of these substitutions generated new repeats and very few generated runs of ...
Cited by 9 - Web Search - ruf.rice.edu - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Characterization of the Murine Lbx2 Promoter, Identification of the Human Homologue, and Evaluation … - Full text - MIT Libraries
F Chen, GB Collin, KC Liu, DR Beier, M Eccles, PM … - Genomics, 2001 - uphs.upenn.edu
... This rela- tionship with DCTN1/Dctn1 also supports our genomic mapping of ... retinal
epithelium suggested that Lbx2 may function downstream of Pax6 during ocular ...
Cited by 1 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Central Nervous System Embryogenesis and Its Failures - Full text - MIT Libraries
FL Lacbawan, M Muenke - Pediatric and Developmental Pathology, 2002 - springerlink.com
... Figure 1. Prechordal plate mesendoderm and its rela- tionship to the embryonic ventral ...
of the distal optic vesicles (such as expression of the genes Pax6 and ET ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Identification and morphogenesis of the eminentia thalami in the zebrafish - Full text - MIT Libraries
MF Wullimann, T Mueller - The Journal of Comparative Neurology, 2004 - doi.wiley.com
... Indexing terms: neuroD; neurogenin; Mash1; nucleus entopeduncularis; Pax6; Zash ... 114).
No direct rela- tionship was noted with the migrated teleostean entope ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Characterization of Opr deficiency in mouse brain: Subtle defects in dorsomedial telencephalon and … - Full text - MIT Libraries
K Furushima, T Murata, H Kiyonari, S Aizawa - DEVELOPMENTAL DYNAMICS, 2005 - doi.wiley.com
... known as Zic1-4 (Aruga et al., 1994, 1996a,b); the rela- tionship of ... alon, Nkx2.1-
and Shh-positive hypo- thalamus and mamillary region, Pax6-positive ventral ...
Web Search - ncbi.nlm.nih.gov

Organ Specification–Growth Control Connection: New In-sights From the Drosophila Eye–Antennal … - Full text - MIT Libraries
M Domın, F Casares - DEVELOPMENTAL DYNAMICS, 2005 - doi.wiley.com
... Con- versely, expression of ey or its mam- malian counterpart PAX6 induces ec- topic
eye ... in a upd-independent manner suggest a more complex rela- tionship than ...
Web Search - ncbi.nlm.nih.gov