Dosage requirement and allelic expression of PAX6 during lens placode formation - Full text - MIT Libraries
CD van Raamsdonk, SM Tilghman - Development, 2000 - dev.biologists.org
... stalk expresses high levels of Pax6 mRNA at E11.5 (see Fig. 7F). This expression
was stronger than in the rest of the lens, suggesting that if the stalk is ...
Cited by 25 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Different roles for Pax6 in the optic vesicle and facial epithelium mediate early morphogenesis of … - Full text - MIT Libraries
JM Collinson, RE Hill, JD West - Development, 2000 - dev.biologists.org
... The rest of the body was washed in PBS then transferred to 20 µl water ... Histological
analysis of the distribution of cells from the Pax6 Sey−Neu/+ × Pax6 Sey ...
Cited by 38 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide … - Full text - MIT Libraries
DC Baulmann, A Ohlmann, C Flugel-Koch, S Goswami, … - Mech. Dev, 2002 - biologie.uni-regensburg.de
... defects in iris and cornea are corrected in Pax6 1/1 $ Pax6 1/2 chimeric mice, in
which lens epithelial cells are of Pax6 1/1 genotype, while the rest of the ...
Cited by 13 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Molecular characterization of Pax6 2Neu through Pax6 10Neu: an extension of the Pax6 allelic series … - Full text - MIT Libraries
J Favor, H Peters, T Hermann, W Schmahl, B … - Genetics, 2001 - genetics.org
... Our observation of homozygous mutant embryos with rudimentary eyes suggests that
the mutation Pax6 7Neu retains some Pax6 rest activity and may represent a ...
Cited by 8 - Web Search - genetics.org - ncbi.nlm.nih.gov

Lens-specific gene recruitment of zeta-crystallin through Pax6, Nrl-Maf, and brain suppressor sites - Full text - MIT Libraries
R Sharon-Friling, J Richardson, S Sperbeck, D Lee, … - Mol Cell Biol, 1998 - mcb.asm.org
... Indeed, transgenic-mouse experiments show that truncated promoters, containing Pax6
and MARE sites but ... Functional analysis of the BPE and the rest of the brain ...
Cited by 22 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to … - Full text - MIT Libraries
G Estivill-Torrus, H Pearson, V van Heyningen, DJ … - Development, 2002 - dev.biologists.org
... the proportions of cells undergoing asymmetrical division in the Pax6 Sey/Sey ... B),
the majority of divisions (almost 80%) were symmetrical; the rest were almost ...
Cited by 27 - Web Search - predator.pnb.uconn.edu - dev.biologists.org - ncbi.nlm.nih.gov - all 5 versions »

PAX6 mutation as a genetic factor common to aniridia and glucose intolerance - Full text - MIT Libraries
T Yasuda, Y Kajimoto, Y Fujitani, H Watada, S … - Diabetes, 2002 - diabetes.diabetesjournals.org
... B, the c.790del4 mutation was identified as a new type of PAX6 gene mutation. ... only
the paired domain and some residues of the linker region and lacks the rest. ...
Cited by 14 - Web Search - diabetes.diabetesjournals.org - ncbi.nlm.nih.gov

The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 … - Full text - MIT Libraries
A Abderrahmani, M Steinmann, V Plaisance, G … - Mol Cell Biol, 2001 - mcb.asm.org
... Indeed, the function of neuronal genes regulated by REST in pancreatic cells remains
unclear. However, genes such as BETA2/NEUROD1, Islet-1, Pax4, Pax6, Nkx2.2 ...
Cited by 11 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

The transcription factor Pax6 is required for development of the diencephalic dorsal midline … - Full text - MIT Libraries
G Estivill-Torrus, T Vitalis, P Fernandez-Llebrez, … - Mech. Dev, 2001 - uma.es
... To better understand the function of Pax6 in the devel- opment of the mouse SCO,
we ... 1 border did not display features distinguishing them from the rest of the ...
Cited by 10 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

PAX6 gene mutations and genotype-phenotype correlations in sporadic cases of aniridia from India …
ABM Reddy, VS Kiran, AK Mandal, SG Panicker, S … - Ophthalmic Genetics, 2003 - taylorandfrancis.metapress.com
... The rest are sporadic. 2 Mutations in the transcription factor gene PAX6 on chromosome
11p13 have been identified to be primarily responsible for aniridia and ...
Web Search

A susceptibility locus for myopia in the normal population is linked to the PAX6 gene region on … - Full text - MIT Libraries
CJ Hammond, T Andrew, YT Mak, TD Spector - Am J Hum Genet, 2004 - journals.uchicago.edu
... Figure 1 LD map for the 17 PAX6 SNPs genotyped (n = 22) over a 32-kb ... suggested a
very high heritability of 0.89 (95% CI 0.86 0.91), with the rest of variance ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

Requirement for Pax6 in corneal morphogenesis: a role in adhesion - Full text - MIT Libraries
J Davis, MK Duncan, WG Robison Jr, J Piatigorsky - J Cell Sci, 2003 - jcs.biologists.org
... The following antibodies were used: anti-Pax6 (1:200; a gift from R. Reed ... Using a
dissection microscope, corneas were isolated from the rest of the eye by ...
Cited by 8 - Web Search - jcs.biologists.org - ncbi.nlm.nih.gov

Six 3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos - Full text - MIT Libraries
O Lagutin, CC Zhu, Y Furuta, DH Rowitch, AP … - Developmental Dynamics, 2001 - doi.wiley.com
... ment of this specific tissue; however, Six3 expression seems to be independent of
Pax6 in the rest of the embryonic tissues, including the optic vesicles. ...
Cited by 20 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Genetic dissection of Pax6 dosage requirements in the developing mouse eye - Full text - MIT Libraries
N Davis-Silberman, T Kalich, V Oron-Karni, T … - Human Molecular Genetics, 2005 - hmg.oxfordjournals.org
... by measuring the iris length in the adult Pax6 flox/+ ; -Cre and littermates Pax6
flox/+ control ... 4F and G), whereas the rest of the eyecup appeared to be of ...
Web Search - hmg.oxfordjournals.org - ingentaconnect.com

Charakterisierung eines neuen Proteins, Mapl-1 und seine Rolle in der Regulation der Pax6-Funktion
P Petrou - deposit.ddb.de
... Rolle in der Regulation der Pax6-Funktion ... 2.1 Mapl-1 als
potentieller Pax6-Interaktionspartner.....17 ...
Web Search - webdoc.sub.gwdg.de - webdoc.gwdg.de

Midline signaling in the primordium of the zebrafish anterior central nervous system - Full text - MIT Libraries
K HATTA, AW POSCHEL, CB KIMMEL - Developmental Biology, 1994 - pnas.org
... forebrain with-that along the rest of the neuraxis. ... RESULTS Beginning near the end
of gastrulation, the homeobox gene pax6 is expressed within the forebrain ...
Cited by 50 - Web Search - pubmedcentral.nih.gov - pnas.org - ncbi.nlm.nih.gov

Prediction by FISH analysis of the occurrence of Wilms tumor in aniridia patients - Full text - MIT Libraries
R Muto, S Yamamori, H Ohashi, M Osawa - American Journal of Medical Genetics, 2002 - doi.wiley.com
... abnorm alities Karyot ypes Copy num ber for ma rker PAX6 D11S2 163 PER WT1 1 F
3/12 ... 1 9 M 17 11/12 À Mulleria n duct rest, cry p- torchid ism, hyposp adias , ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Development and pathology: the Pax gene - Full text - MIT Libraries
C Berry - J Pathol, 2002 - doi.wiley.com
... patterns (although Pax1 and Pax9 have a wider range than the rest of the ... Pax6 protein
is the product that shows the greatest con- servation of function; it is ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Harvesting the mouse genome
M Botcherby - Comparative and Functional Genomics, 2002 - doi.wiley.com
... within the scope of these additional projects, and most are finished with the rest
in shot- gun ... Figure 2. A percentage identity plot (PIP) of the PAX6 locus. ...
Cited by 1 - Web Search - ingentaconnect.com

Inductive interactions direct early regionalization of the mouse forebrain - Full text - MIT Libraries
K Shimamura, JL Rubenstein - Development, 1997 - dev.biologists.org
... the same medial-lateral (ventral-dorsal) patterning mechanisms present in the rest
of the ... kindly provided from Drs R. Derynck (Bmp6), P. Gruss (Pax6), B. Hogan ...
Cited by 207 - Web Search - dev.biologists.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov

Origin of the paired domain - Full text - MIT Libraries
R Breitling, JK Gerber - Development Genes and Evolution, 2000 - springerlink.com
... depicts helical regions as determined from the X-ray structure of human Pax6 as
well ... plus Pax1–9/meso and the rest of the proteins, in accor- dance with the ...
Cited by 8 - Web Search - brc.dcs.gla.ac.uk - ncbi.nlm.nih.gov

The Wilms tumour gene, WT 1, in normal and abnormal nephrogenesis - Full text - MIT Libraries
K Pritchard-Jones - Pediatric Nephrology, 1999 - springerlink.com
... case was there evolution of the WT1 mutation between nephrogenic rest and tumour,
one ... in cloning the first Wilms tumour gene, WT1, and the aniridia gene, PAX6. ...
Cited by 7 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A project for ocular bioinformatics: NEIBank - Full text - MIT Libraries
G Wistow - Mol Vis, 2002 - molvis.org
... For example, the transcription factor Pax6 is expressed in different parts of the
eye ... opticin that deletes a conserved motif without disrupting the rest of the ...
Cited by 17 - View as HTML - Web Search - ncbi.nlm.nih.gov

A LINE element is present at the site of a 300-kb deletion starting in intron 10 of the PAX 6 gene … - Full text - MIT Libraries
M Drechsler, B Royer-Pokora - Human Genetics, 1996 - springerlink.com
... of the L1 element is head- to-head with respect to the PAX6 gene (Fig. ... obtained in
the previous experiments, it was not possible to isolate the rest of the L1 ...
Cited by 21 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Population-based risk estimates of Wilms tumor in sporadic aniridia - Full text - MIT Libraries
K Groenskov, JH Olsen, A Sand, W Pedersen, N … - Hum Genet, 2001 - springerlink.com
... One developed Wilms tumor, and one developed nephro- genic rest (Table 4 summarizes ...
The two remaining patients had dele- tion breakpoints between PAX6 and WT1 ...
Cited by 2 - Web Search

Susceptibility of Nonpromoter CpG Islands to De Novo Methylation in Normal and Neoplastic Cells - Full text - MIT Libraries
C Nguyen, G Liang, TT Nguyen, D Tsao-Wei, S … - Journal of the National Cancer Institute, 2001 - jncicancerspectrum.oupjournals.org
... dependent kinase inhibitors [p15(INK4B) and p16(INK4A)] and the PAX6 gene, which ...
the expected distribution of CpG di- nucleotides relative to the rest of the ...
Cited by 35 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

A Chromosomal Deletion Map of Human Malformations - Full text - MIT Libraries
C Brewer, S Holloway, P Zawalnyski, A Schinzel, D … - The American Journal of Human Genetics, 1998 - journals.uchicago.edu
... were associated with deletion sizes significantly larger than the rest of the group ...
Interestingly, PAX6, which maps to 11p13 and is mutated in individuals with ...
Cited by 44 - Web Search - ukonline.co.uk - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Induction of Oligodendrocyte Fate during the Formation of the Vertebrate Neural Tube
ER Bongarzone - Neurochemical Research, 2002 - kluweronline.com
... migrate out and move through the mantle layer, and colonize the rest of the ... have
been classified as class I or Shh-repressed, for example, Pax6, Pax7, Dbx1 ...
Cited by 2 - Web Search - springerlink.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the … - Full text - MIT Libraries
G Oliver, A Mailhos, R Wehr, NG Copeland, NA … - Development, 1995 - dev.biologists.org
... seems to specifically escape the optic recess region and is found to be located
in the rest of the forebrain (FB) and midbrain (MB); (D) Pax6 is found in some ...
Cited by 217 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Isolation of CpG islands from large genomic clones - Full text - MIT Libraries
S Cross, VH Clark, AP Bird - Nucleic Acids Research, 1999 - nar.oupjournals.org
... an extensive genomic region around the 5[prime]-end of PAX6 is unusual ... for restriction
enzymes which recognise GC-rich sequences, infrequent in the rest of the ...
Cited by 27 - Web Search - nar.oxfordjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 8 versions »

Cranial anomaly of homozygous rSey rat is associated with a defect in the migration pathway of … - Full text - MIT Libraries
N Osumi-Yamashita, S Kuratani, Y Ninomiya, K Aoki, … - Development Growth and Differentiation, 1997 - ncbi.nlm.nih.gov
... the derivative of the medial nasal prominence were present, while the rest of the ...
Homeodomain Proteins; PAX6 protein. PMID: 9079035 [PubMed - indexed for MEDLINE ...
Cited by 19 - Web Search

A project for ocular bioinformatics: NEIBank
S Strategy, G Discovery, V Transcripts - molvis.org
... For example, the transcription factor Pax6 is expressed in different parts of the
eye ... opticin that deletes a conserved motif without disrupting the rest of the ...
Cached - Web Search

Molecular aspects of vertebrate retinal development
SS Zhang, XY Fu, CJ Barnstable - Mol. Neurobiol, 2002 - biomed.humanapress.com
... the third, consisting of cells connecting the optic vesicle to the rest of the ... In
the optic vesicle Pax6 and the basic-helix- loop-helix transcription factor ...
Cited by 9 - Web Search - neurosci.humanapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Ocular and cerebellar defects in zebrafish induced by overexpression of the LIM domains of the islet … - Full text - MIT Libraries
Y Kikuchi, H Segawa, M Tokumoto, T Tsubokawa, Y … - Neuron, 1997 - invivo.caltech.edu
... were indistinguishable between theinjected andthe nor- 1995), leaving expression
in the rest of the brain only ... Pax6 mRNA was also expressed in the diencephalon ...
Cited by 23 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Stem Cells in the Vertebrate Retina - Full text - MIT Libraries
TA Reh, AJ Fischer, TA Reh, F Alert - Brain Behavior and Evolution, 2001 - content.karger.com
... most patch of labeled cells is formed during embryogenesis, whereas the rest of
the ... Pax6 and Chx10 are expressed by cells of the progenitor zone and the stem ...
Cited by 12 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

Defining pallial and subpallial divisions in the developing Xenopus forebrain - Full text - MIT Libraries
I Bachy, J Berthon, S Retaux - Mechanisms of Development, 2002 - cnrs-gif.fr
... serves as the limiting landmark between the telencephalon and the rest of the forebrain
(Figs. 1I, J and 2G, see also inset of Fig. 1). x-Pax6 is strongly co ...
Cited by 4 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

FGF signaling through FGFR 1 is required for olfactory bulb morphogenesis - Full text - MIT Libraries
JM Hebert, M Lin, J Partanen, J Rossant, SK … - Development, 2003 - dev.biologists.org
... Compared with the rest of the telencephalon, the OB undergoes unique ... the frontonasal
mesenchyme to the telencephalon and induction of Pax6 expression (LaMantia ...
Cited by 17 - Web Search - stanford.edu - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

oto is a homeotic locus with a role in anteroposterior development that is partially redundant with … - Full text - MIT Libraries
JS Zoltewicz, NW Plummer, MI Lin, AS Peterson - Development, 1999 - dev.biologists.org
... anterior axis led us to re-examine the development of the rest of the ... kind gifts
of: Fgf8 (Gail Martin), dHand and eHand (Deepak Srivistava), Pax6 (Peter Gruss ...
Cited by 9 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Tyrosine phosphorylation sites on FRS2 {alpha} responsible for Shp2 recruitment are critical for … - Full text - MIT Libraries
N Gotoh, M Ito, S Yamamoto, I Yoshino, N Song, Y … - Proc Natl Acad Sci US A, 2004 - pnas.org
... of the Frs2 2F/2F embryos had bilateral microphthalmia, and of the rest, 30% had ...
This phenotype is very similar to that of Pax6 Sey/Sey embryos and contrasts ...
Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Phosphorylation of the Transactivation Domain of Pax 6 by Extracellular Signal-regulated Kinase and … - Full text - MIT Libraries
I Mikkola, JA Bruun, G Bjoerkoey, T Holm, T … - J Biol Chem, 1999 - jbc.org
... The GAL4-Pax6(353–395) construct was made from GAL4-Pax6(353–437) by deletion of
the NdeI-XbaI fragment followed by religation of the rest of the plasmid. ...
Cited by 19 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Recurrent 17 bp duplication in PITX 3 is primarily associated with posterior polar cataract(CPP 4) - Full text - MIT Libraries
V Berry, Z Yang, PKF Addison, PJ Francis, A … - Journal of Medical Genetics, 2004 - jmedgenet.com
... PAX6 mutations were identified in heterogeneous anterior-segment malformations in
a family ... role in lens development than in the development of the rest of the ...
Cited by 1 - Cached - Web Search - zhang.hmbg.utah.edu - dx.doi.org - jmg.bmjjournals.com - all 6 versions »

Arcuate plan of chick midbrain development - Full text - MIT Libraries
TA Sanders, A Lumsden, CW Ragsdale - J Neurosci, 2002 - jneurosci.org
... only a very few nuclei form frank longitudinal cell columns, and the rest appear
too ... OTX2 (1.5 kb) (Bally-Cuif et al., 1995 ), PAX3 (660 bp) and PAX6 (540 bp ...
Cited by 5 - Web Search - jneurosci.org - ncbi.nlm.nih.gov

New Sequence Boosts Rats' Research Appeal - Full text - MIT Libraries
E Pennisi, CS HARBOR, NEW YORK - Science, 2004 - sciencemag.org
... Rat-specific DNA comprises the rest, about 750 million bases. ... The rats have a mutation
in the Pax6 gene, and there is some indication that Pax6 expression is ...
Web Search - sciencemag.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Early stages of oligodendrocyte development in the embryonic murine spinal cord proceed normally in … - Full text - MIT Libraries
DJ Nicolay, JR Doucette, AJ Nazarali - Glia, 2004 - doi.wiley.com
... Developmental Studies Hybridoma Bank; E12.5, 1:4; rest, 1:2), anti-Hoxa2 (Hao et
al., 1999; E12.5, 1:3,000; rest, 1:1,500), and anti-Pax6 (Develop- mental ...
Web Search - ncbi.nlm.nih.gov

Ultraconserved Elements in the Human Genome - Full text - MIT Libraries
G Bejerano, M Pheasant, I Makunin, S Stephen, WJ … - Science, 2004 - science.com
... exonic elements are located in introns of known genes and the rest are intergenic ...
include the neuroretina-specific enhancer in the fourth intron of PAX6 (uc.328 ...
Cited by 56 - Cached - Web Search - sciencemag.org - soe.ucsc.edu - imb-jena.de - all 9 versions »

Controversies and advances in the management of Wilms' tumour - Full text - MIT Libraries
K Pritchard-Jones - Archives of Disease in Childhood, 2002 - adc.bmjjournals.com
... from normal undifferentiated metanephric blastema through nephrogenic rest to Wilms ...
resolution karyotyping using probes for the contiguous PAX6, calmodulin, and ...
Cited by 5 - Web Search - adc.bmjjournals.com - dx.doi.org - ncbi.nlm.nih.gov

A Conserved Retina-Specific Gene Encodes a Basic Motif/Leucine Zipper Domain - Full text - MIT Libraries
A Swaroop, J Xu, H Pawar, A Jackson, C Skolnick, N … - Proceedings of the National Academy of Sciences - pnas.org
... Sci. Home page Y. Liu, YC Shen, JS Rest, PA Raymond, and DJ Zack Isolation and ... J.
Imaki, and S. Nishi Regulation of c-maf gene expression by Pax6 in cultured ...
Cited by 106 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Mini-Review Misexpression of genes in brain vesicles by in ovo electroporation - Full text - MIT Libraries
H Nakamura, Y Watanabe, J Funahashi - Development Growth & Differentiation, 2000 - dx.doi.org
... 1 s so that a pulse of 50 ms was followed by a 950 ms rest phase. ... product was also
detected by 2 h after electroporation, and repression of Pax6 by introduced ...
Cited by 25 - Web Search - blackwell-synergy.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

FOXP2 in focus: what can genes tell us about speech and language - Full text - MIT Libraries
GF Marcus, SE Fisher - Trends Cogn. Sci, 2003 - ai.mit.edu
... For example, our ‘master control gene’ for eye-building, PAX6, is also essential
for ... If the rest of biology is any guide, the machinery of language is ...
Cited by 16 - View as HTML - Web Search - cogpsy.skku.ac.kr - big.cs.uiuc.edu - library.ibp.ac.cn - all 10 versions »

A novel fork head gene mediates early steps during Xenopus lens formation - Full text - MIT Libraries
KL Kenyon, SA Moody, M Jamrich - Development, 1999 - dev.biologists.org
... entire placodal region has a higher lens-forming potential than the rest of the ... Both
otx2 and pax6 have been implicated in the process of lens bias (Zygar et al ...
Cited by 21 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov