Quantitation of PAX6 and PAX6 (5a) transcript levels in adult human lens, cornea, and monkey retina - Full text - MIT Libraries
W Zhang, K Cveklova, B Oppermann, M Kantorow, A … - Mol. Vis, 2001 - molvis.org
... The PAX6 and TBP sequences were obtained from Genbank under accession
numbers M93650 and M34960, respectively. Oligonucleotides ...
Cited by 10 - View as HTML - Web Search - molvis.org - ncbi.nlm.nih.gov

Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker … - Full text - MIT Libraries
HE Xu, MA Rould, W Xu, JA Epstein, RL Maas, CO … - Genes Dev, 1999 - genesdev.org
... 1993a ,b ), and it has been proposed that TBP evolved via ancient gene duplications.]. ...
Of the 18 Pax6 paired domain missense mutations known to us (Hanson et al ...
Cited by 61 - Web Search - uphs.upenn.edu - 128.95.44.130 - pubmedcentral.nih.gov - all 8 versions »

Bedeutung der Homoeodomaene des Transkriptionsfaktors Pax6 fuer die Aktivierung des Glukagon-Gens …
S TEICHLER - webdoc.sub.gwdg.de
... Pax6-dPD/E6 Pax6 mit zum Teil deletierter Paired-Domäne Pax6-WT Pax6-Wildtyp ... Taq
Thermus aquaticus TBE Tris-Borat-EDTA TBP TATA-Box-bindendes Protein ...
View as HTML - Web Search

Charakterisierung eines neuen Proteins, Mapl-1 und seine Rolle in der Regulation der Pax6-Funktion
P Petrou - deposit.ddb.de
... 2000; Ericson, 1997; Goulding et al., 1993) Pax6 -/- Mäuse ... mit dem TATA-Box
bindenden Protein (TBP) und dem Retinoblastoma-Protein (Rb) ein ...
Web Search - webdoc.sub.gwdg.de - webdoc.gwdg.de

Transcriptional regulation by the MAP kinase signaling cascades - Full text - MIT Libraries
SH Yang, AD Sharrocks, AJ Whitmarsh - Gene, 2003 - www-unix.oit.umass.edu
... JNK 55–59 STAT1, CDX2, NFATp, NFATc4, p73 p38 60–64 HSF-1 ERK, JNK 65, 66 Pax6,
TBP ERK, p38 67–69 p53, SMAD3 ERK, JNK, p38 70–74 TIF-1A ERK, RSK 75 ...
Cited by 48 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Getting your Pax straight: Pax proteins in development and disease
N Chi, JA Epstein - Trends Genet, 2002 - instruct.uwo.ca
... In addition, Pax2, Pax3, Pax4, Pax5 and Pax6 can repress transcription of some ... Several
Pax proteins can interact with the TATA-binding protein (TBP) and with ...
Cited by 54 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulation of alpha A-crystallin Gene Expression - Full text - MIT Libraries
JG Ilagan, A Cvekl, M Kantorow, J Piatigorsky, CM … - J Biol Chem, 1999 - jbc.org
... open) to be functional transcriptional regulatory elements of the mouse and chicken
A-crystallin genes: USF, AP-1, CREB/CREM, Pax6, L-Maf, TBP, and A-CRYBP1 (11 ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov

Fundamentals of Transcription Factors and Their Impact on Pancreatic Development and Cancer
JAKR Urrutia - Pancreatology, 2003 - content.karger.com
... with one of its compo- nents, RNA helicase A. p300/CBP also interact with TFIIB
and TBP, a component of TFIID ... Pax6 activator formation of alpha cells 30–32 ...
Web Search - content.karger.com

Annual Review of Entomology - Full text - MIT Libraries
DN Arnosti - Annual Review of Entomology, 2003 - ento.annualreviews.org
... Alternative forms of TBP protein have been found in Drosophila; these ... stripe patterning,
and a short element containing multimerized Pax6/eyeless factor sites ...
Web Search - ento.annualreviews.org

Analysis AND Function OF Transcriptional - Full text - MIT Libraries
DN Arnosti - Annu. Rev. Entomol, 2003 - ento.annualreviews.org
... Alternative forms of TBP protein have been found in Drosophila; these ... stripe patterning,
and a short element containing multimerized Pax6/eyeless factor sites ...
Cited by 16 - Web Search - bch.msu.edu - genetik.uni-koeln.de - ncbi.nlm.nih.gov - all 6 versions »

BSAP(Pax 5)-Importin alpha 1(Rch 1) Interaction Identifies a Nuclear Localization Sequence - Full text - MIT Libraries
CR Kovac, A Emelyanov, M Singh, N Ashouian, BK … - J Biol Chem, 2000 - jbc.org
... BSAP interacts with the retinoblastoma protein Rb and the TATA-binding protein TBP
(18 ... and central domain segments of other Pax proteins, ie quail Pax6 (25) and ...
Cited by 8 - Web Search - cellbio.aecom.yu.edu - aecom.yu.edu - ncbi.nlm.nih.gov - all 6 versions »

Independent Development of Pancreatic-and-Cells From Neurogenin3-Expressing Precursors - Full text - MIT Libraries
OD Madsen, P Serup - DIABETES, 2000 - diabetes.diabetesjournals.org
... Primer sequences for INS, GLU, NeuroD, G6PDH, tubulin, Sp-1, TBP, and Id-1 ... for glucagon
and insulin together with the nuclear markers PDX1, ISL1, PAX6, and BRN4 ...
Cited by 103 - Web Search - diabetes.diabetesjournals.org - ncbi.nlm.nih.gov

Neurogenin 3 is differentially required for endocrine cell fate specification in the intestinal and … - Full text - MIT Libraries
M Jenny, C Uhl, C Roche, I Duluc, V Guillermin, F … - The EMBO Journal, 2002 - embojournal.npgjournals.com
... (D) RT–PCR analysis of gene expression in P 1 intestine. Expression of Pax6 is lost
in ngn3-deficient intestine. TBP was used as an internal standard. ...
Cited by 36 - Web Search - nature.com - emboj.org - betacell.org - all 9 versions »

analysis in Drosophila melanogaster
G product Selected - www-biology.ucsd.edu
... Abd-B § Transcription Ffactor 6–10 Aniridia PAX6 ey § , toy § Transcription factor
11–14 ... SCA17 (also known asTBP) Tbp § TATA binding protein ...
Web Search - nature.com

Critical reduction in b-cell mass results in two distinct outcomes over time - Full text - MIT Libraries
DR Laybutt, M Glandt, G Xu, YB Ahn, N Trivedi, S … - J Biol Chem, 2003 - jbc.org
... in Levels of Islet-associated Transcription Factor mRNA—After normalization of the
specific gene to an internal control gene (TBP, -tubulin, cyclophilin ... TBP ...
Cited by 9 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Foxe3 haploinsufficiency in mice: a model for Peters’ anomaly - Full text - MIT Libraries
M Ormestad, A Blixt, A Churchill, T Martinsson, S … - Invest Ophthalmol Vis Sci, 2002 - iovs.org
... A, Ross, A, Lee, M, et al (1996) Influence of PAX6 gene dosage ... FREAC-2 contains two
functionally redundant activation domains and interacts with TBP and TFIIB ...
Cited by 12 - Web Search - iovs.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Ectopic expression of the beta-cell specific transcription factor Pdx 1 inhibits glucagon gene … - Full text - MIT Libraries
B Ritz-Laser, BR Gauthier, A Estreicher, A Mamin, … - Diabetologia, 2003 - springerlink.com
... still repressed transcriptional activation of the glucagon gene promoter by Pax6
and Cdx-2 ... directly interact with the TATA binding protein within TFIID (TBP) [52 ...
Cited by 1 - Web Search - medecine.unige.ch - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and … - Full text - MIT Libraries
KH Kaestner, J Katz, Y Liu, DJ Drucker, G Schutz - Genes Dev, 1999 - genesdev.org
... TBP served as loading control. ... For instance, it was shown that Pax6 is
required for the differentiation of cells (St-Onge et al. ...
Cited by 69 - Web Search - genesdev.org - med.upenn.edu - pubmedcentral.nih.gov - all 8 versions »

Identification of a portable repression domain and an E1A-responsive activation domain in Pax4: a … - Full text - MIT Libraries
Y Fujitani, Y Kajimoto, T Yasuda, TA Matsuoka, H … - Mol Cell Biol, 1999 - mcb.asm.org
... of the basal transcription machinery such as TATA-binding protein (TBP), as recently ...
reported that whereas Pax4 and Pax6 have similar DNA-binding specificities ...
Cited by 16 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar … - Full text - MIT Libraries
JL Bennicelli, RH Edwards, FG Barr - Genetics, 1996 - dx.doi.org
... T. Johansen Phosphorylation of the Transactivation Domain of Pax6 by Extracellular ...
Functionally Redundant Activation Domains and Interacts with TBP and TFIIB J ...
Cited by 50 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Recognition of specific DNA sequences - Full text - MIT Libraries
CW Garvie, C Wolberger - Mol. Cell, 2001 - qb.fcen.uba.ar
... (L) TATA binding protein (TBP). (M) Rel homology domain (immunoglobulin-type fold):
NF- B. Page 3. Review 939 ... (A) POU domain: Oct-1. (B) Paired domain: Pax6. ...
Cited by 21 - View as HTML - Web Search - wisc.edu - ncbi.nlm.nih.gov - all 4 versions »

Involvement of cadherins 7 and 20 in mouse embryogenesis and melanocyte transformation - Full text - MIT Libraries
R Moore, D Champeval, L Denat, SS Tan, F Faure, S … - Oncogene, 2004 - nature.com
... Cad20 production in the developing optic vesicles and pT resembles the
expression patterns of Necab, Six3 and Pax6 on E9.5 and 10.5. ...
Web Search - ncbi.nlm.nih.gov

The Islet{beta} Cell-enriched MafA Activator Is a Key Regulator of Insulin Gene Transcription - Full text - MIT Libraries
L Zhao, M Guo, T Matsuoka, DK Hagman, SD Parazzoli … - J Biol Chem, 2005 - jbc.org
... 7, 8). Human heterozygous carriers of dysfunctional mutations in PAX6 (20), BETA2 ...
the relative change in MafA and the TATA-binding protein (TBP) was determined ...
Cited by 2 - Web Search - jbc.org - ncbi.nlm.nih.gov

Functional interactions between alternatively spliced forms of Pax 6 in crystallin gene regulation … - Full text - MIT Libraries
BK Chauhan, Y Yang, K Cveklova, A Cvekl - Nucleic Acids Research, 2004 - pubmedcentral.nih.gov
... antibody against Pax6 from Developmental Biology Hybridoma Bank (Iowa City, IA).
Antibodies against Pax2/5/8 (sc-7747), Pax3/7 (sc-7748) and TBP (sc-273) were ...
Cited by 2 - Web Search - nar.oxfordjournals.org - nar.oupjournals.org - ingentaconnect.com - all 7 versions »

Microarray analysis of gene expression in human donor sclera - Full text - MIT Libraries
TL Young, GS Scavello, PC Paluru, JD Choi, EF … - Mol Vis, 2004 - molvis.org
... DEK 6p23 NM_021145 cyclin D binding myb-like DMTF1 7q21 transcription factor 1
NM_001938 down-regulator of transcription DR1 1p22.1 1, TBP-binding (negative ...
Cited by 3 - View as HTML - Web Search - molvis.org - scavello.net - ncbi.nlm.nih.gov

SPI-B Activates Transcription via a Unique Proline, Serine, and Threonine Domain and Exhibits DNA … - Full text - MIT Libraries
S Rao, A Matsumura, J Yoon, MC Simon - J Biol Chem, 1999 - jbc.org
... B can also bind to other PU.1 interacting proteins such as c-Jun, TBP, NF-IL6 ... been
identified in GATA factors (45) as well as the homeodomain protein Pax6 (50 ...
Cited by 13 - Web Search - jbc.org - ncbi.nlm.nih.gov

A Natural CYP2B6 TATA Box Polymorphism (–82T-> C) Leading to Enhanced Transcription and Relocation … - Full text - MIT Libraries
J Zukunft, T Lang, T Richter, KI Hirsch-Ernst, AK … - Mol Pharmacol, 2005 - molpharm.org
... PAX6, Pax-6 paired domain binding site; ATF6, activating transcription factor 6;
MAZ ... B, recombinant TBP was incubated with probes TATA and CATA (described above ...
Cached - Web Search - molpharm.aspetjournals.org - molpharm.aspetjournals.org - ncbi.nlm.nih.gov - all 5 versions »

Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2 … - Full text - MIT Libraries
Y Qiu, M Guo, S Huang, R Stein - Mol Cell Biol, 2002 - mcb.asm.org
... Binding between p300 and basal factors, like the TATA-binding protein (TBP) and
TFIIB ... the p300 complex formed with the insulin enhancer factors PAX6 (23), PDX-1 ...
Cited by 29 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Human Molecular Embryogenesis: An Overview - Full text - MIT Libraries
LL Oligny - Pediatric and Developmental Pathology, 2001 - springerlink.com
... This causes multiple proteins to coalesce with the TBP to form a co ... syndrome types
I and III, craniofacial-deafness-hand syndrome PAX6: aniridia, Peter’s ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Opposing actions of Arx and Pax 4 in endocrine pancreas development - Full text - MIT Libraries
P Collombat, A Mansouri, J Hecksher-Sorensen, P … - Genes & Development, 2003 - genesdev.org
... Targeted disruption of the paired-box-containing gene Pax6 or of the LIM ... phosphate
dehydrogenase (G6PDH) and the TATA-box-binding protein (TBP) reference genes ...
Cited by 5 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Markedly reduced evolutionary rates of transcription factors and cytoplasmic ribosomal RNAs and …
D Hoshiyama, K Kuma, T Miyata - Genome Inform Ser Workshop Genome Inform, 2004 - jsbi.org
... In the Latter period, however, the relative rate of TBP is completely reduced (R2 ...
Sosa-Pineda, B., Chowdhury, K., Mansouri, A., and Gruss, P., Pax6 is required ...
View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Derivation and Comparative Assessment of Retinal Pigment Epithelium from Human Embryonic Stem Cells …
I Klimanskaya, J Hipp, KA Rezai, M West, A Atala, … - Cloning & Stem Cells, 2004 - dx.doi.org
... activators normally required for the eye development, including rx/rax, chx10/
vsx-2/alx, ots-1, otx-2, six3/optx, six6/optx2, mitf, and pax6/pax2 (Baumer ... PAX6 ...
Cited by 3 - Web Search - liebertonline.com - bu.edu - liebertpub.com - all 10 versions »

Anterior pituitary development and Pit-1/GHF-1 transcription factor - Full text - MIT Libraries
M de la Hoya, V Vila, O Jimenez, JL Castrillo - Cellular and Molecular Life Sciences(CMLS), 1998 - springerlink.com
... step, but expression of the homoeotic genes Rpx (Hesx1), Six3, Pax6 and Six1 ... TRE,
TPA-responsive element; CRE, cAMP-responsive element; TATA, TBP-binding site. ...
Cited by 7 - Web Search - ncbi.nlm.nih.gov

Molecular profiling: gene expression reveals discrete phases of lens induction and development in … - Full text - MIT Libraries
BE Walter, Y Tian, AK Garlisch, ME Carinato, MB … - Mol Vis, 2004 - molvis.org
... For example, mouse lenses con- taining constituitively-active Pax6 revealed that
at least 500 genes may lie downstream of Pax6 during lens development [12-14]. ...
Cited by 1 - View as HTML - Web Search - molvis.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The embryonic expression pattern of 40 murine cDNAs homologous to Drosophila mutant genes(Dres): a … - Full text - MIT Libraries
A Bulfone, C Gattuso, A Marchitiello, C Pardini, E … - Human Molecular Genetics, 1998 - hmg.oupjournals.org
... For example, the human gene responsible for aniridia (PAX6) is homologous ... 132,
TBP-associated factor 150kD, TATA-binding protein associated factor, -, -, AA028778 ...
Cited by 8 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Chronic Hyperglycemia Triggers Loss of Pancreatic beta Cell Differentiation in an Animal Model of … - Full text - MIT Libraries
JC Jonas, A Sharma, W Hasenkamp, H Ilkova, G … - J Biol Chem, 1999 - jbc.org
... the rat ribosomal phosphoprotein P0 (RRPP0) or the TATA-binding protein (TBP) to
correct for ... was also observed for the mRNA levels of Nkx6.1, Pax6, and the ...
Cited by 106 - Web Search - jbc.org - ncbi.nlm.nih.gov

BMC Biochemistry - Full text - MIT Libraries
C de la Fuente, F Santiago, L Deng, C Eadie, I … - BMC Biochemistry, 2002 - biomedcentral.com
... TAFII55). [Acc# U18062] 3.1 mRNA for TBP associated factor, TAFII68. ... ATF6).
[Acc# AF005887] 0.16 Paired box gene (PAX6) homologue. ...
View as HTML - Web Search - bmc.ub.uni-potsdam.de

Variation of serotonergic gene expression: neurodevelopment and the complexity of response to …
KP Lesch - Eur Neuropsychopharmacol, 2001 - uni-wuerzburg.de
... comprises multiple factors, including the TATA box binding protein (TBP) with
TBP-associated factors ... tion factors (eg Tbr1, Gbx1, Pax6 ) as well as secreted ...
Cited by 13 - View as HTML - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Subunits of the Heterotrimeric Transcription Factor NF-Y Are Imported into the Nucleus by Distinct …
J Kahle, M Baake, D Doenecke, W Albig - mcb.asm.org
... The paired-type homeodomain transcription factors Pax6, Pax3, and Crx (56), the
SUMO-1/sentrin-conjugating enzyme hUBC9, and MGN binding protein RBM8 (Y14) (50 ...
Web Search - mcb.asm.org

Ethidium Bromide Provides a Simple Tool for Identifying Genuine DNA-Independent Associations - Full text - MIT Libraries
J Lai, W Herr - Proceedings of the National Academy of Sciences - pnas.org
... Kamachi, M. Uchikawa, A. Tanouchi, R. Sekido, and H. Kondoh Pax6 and SOX2 ... of Yeast
Transcriptional Regulator, Mot1, with TATA Box-binding Protein (TBP) J. Biol ...
Web Search - adsabs.harvard.edu

Transcriptional regulation in mammalian pituitary development and disease
KW Sloop, GE Parker, SJ Rhodes - Current Genomics, 2001 - ingentaconnect.com
Page 1. Current Genomics, 2001, 2, 379-397 379 1389-2029/01 $20.00+.00 © 2001
Bentham Science Publishers Ltd. Transcriptional Regulation ...
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The psychopharmacogenetic-neurodevelopmental interface in serotonergic gene pathways
KP Lesch, J Benninghoff, A Schmitt - Pharmacogenetics of psychotropic drugs, 2002 - uni-wuerzburg.de
... factors, including the TATA box-binding protein (TBP) with TBP-associated factors ...
also require several transcription factors (eg, Tbr1, Gbx1, Pax6) as well as ...
Cited by 1 - View as HTML - Web Search

THE ROLE OF PU. 1 IN B-LYMPHOCYTE DEVELOPMENT AND FUNCTION
S RAO, MC SIMON - doi.wiley.com
... The N-terminus of PU.1, (aa 1—75), also interacts with TATA-binding protein (TBP)
and the retionoblastoma protein (Rb) by affinity chromatography (Hagemeier ...
Web Search

Pax3 and the splotch mutations: structure, function, and relationship to teratogenesis, including …
AF Machado, LJ Martin, MD Collins - Curr. Pharm. Design, 2001 - ingentaconnect.com
... in all of the Pax proteins, including Pax3, and the structural data from Pax6 and
Pax8 ... factors including AP-1, AP-2, SP1, TFIID, PEA3, UBP-1, EFT, TBP, and MEF ...
Cited by 7 - Web Search - bentham.org - bentham.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Molecular and biochemical analysis of the MODY syndromes - Full text - MIT Libraries
WE Winter - Pediatric Diabetes, 2000 - dx.doi.org
... Once TBP (TATA-box binding protein) binds to the TATA box, TAF [TAT-box ... islet, Pax4
is important for beta and delta cell formation whereas Pax6 is important ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA … - Full text - MIT Libraries
KD Robertson, PA Jones - Mol. Cell. Biol, 1998 - mcb.asm.org
... from promoters which do not contain p53 binding sites (6, 13, 34, 38, 58, 69) through
sequestration of the TATA binding protein (TBP) and inhibition of ...
Cited by 156 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Molecular basis of non-syndromic tooth agenesis: mutations of MSX 1 and PAX 9 reflect their role in … - Full text - MIT Libraries
A Mostowska, A Kobielak, WH Trzeciak - European Journal Of Oral Sciences, 2003 - blackwell-synergy.com
... The protein product of MSX1 functions as a repressor of gene transcription and
interacts with TATA box-binding protein (TBP) and other components of the core ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non- … - Full text - MIT Libraries
G Wistow, SL Bernstein, MK Wyatt, RN Fariss, A … - Mol Vis, 2002 - molvis.org
Page 1. Molecular Vision 2002; 8:205-20 <http://www.molvis.org/molvis/v8/a27> Received
31 August 2001 | Accepted 14 December 2001 | Published 15 June 2002 ...
Cited by 28 - View as HTML - Web Search - molvis.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development - Full text - MIT Libraries
M Bouchard, P Pfeffer, M Busslinger - Development, 2000 - dev.biologists.org
... constitutes an interaction surface for the retinoblastoma (Rb) and
TATA-binding (TBP) proteins (Eberhard and Busslinger, 1999). ...
Cited by 41 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Gene expression profile of serial samples of transformed B-cell lymphomas - Full text - MIT Libraries
S de Vos, WK Hofmann, TM Grogan, U Krug, M Schrage … - Lab Invest, 2003 - nature.com
... MIP-3b, exodus-3 Transcription factors Up U52682 IRF4 MUM1 X79439 NOTCH3
Receptor M93650 PAX6 Transcription factor Down U15460 B ...
Cited by 12 - View as HTML - Web Search - nature.com - knm1.ibe.med.uni-muenchen.de - ncbi.nlm.nih.gov