Functional and binding studies of HS3. 2 of the beta-globin locus control region - Full text - MIT Libraries
JM Molete, H Petrykowska, M Sigg, W Miller, R … - Gene, 2002 - ingentaconnect.com
... We also show that nuclear proteins including GATA1 and Oct1 bind specifically to
sequences within HS3.2. However, the protein Pbx1, whose binding site is the ...
Cited by 3 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... CDPCR3HD PBX1 1177.3 FREAC7 GATA1 153.0 CDP GATA1 52.0 P300 SREBP1 27.9 ... CEBP
CHOP 559.1 CREB PAX3 125.3 GATA1 PBX1 46.3 AP2 MYCMAX 24.8 ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

Frequencies of the major subgroups of precursor B-cell acute lymphoblastic leukemia in Indian …
TM Med - Trends Mol Med, 2002 - nature.com
... TEL-AML1 mBCR-ABL E2A-PBX1 MLL-AF4 ... of AML occurring in young patients with Down’s
syndrome (DS), 2 in which it is associated with acquired GATA1 mutations. ...
Web Search

Rapid Generation of de novo Biological Pathways from Large-Scale Gene Expression Data Using the …
DC Siu - ingenuity.com
... PIN1, PTPRC, GATA1, SPI1, CEBPB, CEBPE, QKI, MHC class II, SCD1, Calmodulin, NFIC,
Pi-Plc, Tubulin, PLP1, Fgfr PBX1,TR ALPHA, Malic Enzyme, HOXA9, HOXA11 ...
View as HTML - Web Search

Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood … - Full text - MIT Libraries
KB Gale, AM Ford, R Repp, A Borkhardt, C Keller, … - Proc Natl Acad Sci USA, 1997 - dx.doi.org
... King, B. Stewart, B. Gibson, I. Roberts, and P. Vyas Natural history of GATA1 mutations
in ... and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in ...
Cited by 121 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Progress in Hematology
Y Hayashi - cardenjennings.metapress.com
... for both T-cell ALL (T-ALL) CD3D and E2A-PBX1 (PBX1), whereas 7 to ... regulation of
transcription factors involved in early hemato- poiesis (TAL1, GATA1, and EKLF ...
Web Search

Hemoglobin switching: new insights.
KR Peterson - Current Opinion in Hematology, 2003 - co-hematology.com
... The nuclear proteins GATA1 and Oct1 bind specifically to sequences within
5'HS3.2. However, Pbx1 does not bind even though 5'HS3.2 contains a highly conserved ...
Cited by 2 - Web Search - co-hematology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Oncogenes et leucemies: historique et perspectives
S Gisselbrecht, BG Roussy - M e decine et Science, 2003 - erudit.org
... au domaine de fixation à l’ADN de la protéine à homéodomaine PBX1 alors que dans
la ... Ces leucémies présentent des mutations ponctuelles du gène GATA1. ...
Cited by 2 - Cached - Web Search

Regulatory Sequence Analysis of Coclustering Genes
A TFBS - ahavj.ahajournals.org
... GATA1, 14/52=27, 11/29=38, 4/11=36, 3/6=50, 6/16=38, 2/3=67, 1/4=25, 2/9=22,
0/1=0, 1/1=100. ... PBX1, 12/52=23, 9/29=31, 3/11=27, 1/6=17, 3/16=19, 2/3=67, 3/4=75, ...
Web Search

acquises de la cellule souche hematopoietique ou d’un precurseur deja commis vers les lignees …
S YNTHESE - MEDECINE/SCIENCES, 2003 - ist.inserm.fr
... au domaine de fixation à l’ADN de la protéine à homéodomaine PBX1 alors que dans
la ... Ces leucémies présentent des mutations ponctuelles du gène GATA1. ...
View as HTML - Web Search - erudit.org

Leukaemia- a developmental perspective - Full text - MIT Libraries
S Izraeli - British Journal of Haematology, 2004 - blackwell-synergy.com
... This review describes three examples of this general paradigm of leukaemogenesis:
RUNX1 abnormalities in acute leukaemias, GATA1 mutations in the leukaemias of ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... family Description GATA1 02 GATA-binding factor 1 GATA1 03 GATA-binding factor 1
GATA1 04 GATA ... PBX1 02 Homeo domain factor Pbx-1 Core should be CAATC not CAAT ...
View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Chromosomal Abnormalities, Cancer and Mouse Models: The Critical Role of Translocation-Associated …
WIS CANCER, IOF ONCOGENES - Current Genomics, 2000 - ingentaconnect.com
... which is typically found in pre-B cell acute lymphoblastic leukemias, were not
expressed in E2A-PBX1 immortalized mouse ... GATA1 pr -c-MYC FVB/N Erythroleukemia ...
Web Search

Hematopoietic, angiogenic and eye defects in Meis 1 mutant animals - Full text - MIT Libraries
T Hisa, SE Spence, RA Rachel, M Fujita, T Nakamura … - The EMBO Journal, 2004 - embojournal.npgjournals.com
... in the proximal limb buds of mice (Saleh et al, 2000) and a Pbx1 knockout has ...
transactivate the platelet factor 4 (Pf4) gene in combination with GATA1 and ETS1 ...
Cited by 9 - Web Search - nature.com - embojournal.npgjournals.com - ncbi.nlm.nih.gov

Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion.
SM Onnebo, MM Condron, DO McPhee, GJ Lieschke, AC … - Experimental Hematology, 2005 - eanimal.snu.ac.kr
... tel-jak2a (D,F,H), were analyzed for expression of gata1 at 24 ... Estrogen-dependent
E2a/Pbx1 myeloid cell lines exhibit conditional differentiation that can be ...
View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

HOX and Non-HOX Homeobox Genes in Leukemic Hematopoiesis - Full text - MIT Libraries
BM Owens, RG Hawley - Stem Cells, 2002 - stemcells.alphamedpress.org
... Hoxb8 requires interaction with Pbx1 to arrest myeloid differentiation [96]. ... to DLX7
in K562 lead to apoptosis and decreases in c-MYC and GATA1 levels. ...
Cited by 32 - Web Search - stemcells.alphamedpress.org - dx.doi.org - ncbi.nlm.nih.gov

Polymorphism, shared functions and convergent evolution of genes with sequences coding for … - Full text - MIT Libraries
H Lavoie, F Debeane, QD Trinh, JF Turcotte, LP … - Human Molecular Genetics, 2003 - hmg.oupjournals.org
... domains appeared only in mammals in HOXD8, HOXA11, HOXD11, HOXA13, HOXD13, GATA1,
GATA4 and ... one is longer in zebrafish than in human and chicken (PBX1) (Fig. ...
Cited by 8 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

The cardiac transcription factors Nkx 2-5 and GATA-4 are mutual cofactors - Full text - MIT Libraries
D Durocher, F Charron, R Warren, RJ Schwartz, M … - The EMBO Journal, 1997 - embojournal.npgjournals.com
... Bieker, JJ and Wojchowski, DM (1996) Functional interaction of GATA1 with erythroid ...
Q. and Kamps, MP (1996) Structural determinants within Pbx1 that mediate ...
Cited by 207 - Web Search - nature.com - emboj.org - ncbi.nlm.nih.gov - all 6 versions »

Bibliography Current world literature
M Gabbianelli, U Testa, A Massa, E Pelosi, NM … - Current Opinion in Hematology, 2002 - co-hematology.com
... R, O'Gorman S, et al.: The Hox cofactor and proto-oncogene Pbx1 is required ... Jasinski
M, Keller P, Fujiwara Y, Orkin SH, Bessler M: GATA1-Cre mediates Piga gene ...
Web Search

GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene … - Full text - MIT Libraries
JL Sepulveda, N Belaguli, V Nigam, CY Chen, M … - Mol. Cell. Biol, 1998 - mcb.asm.org
... increases the transcriptional activity of Nkx-2.5 by the interaction of GATA-4 with
Nkx-2.5 might be similar to the effects of Extradenticle and Pbx1 on the ...
Cited by 130 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

[CITATION] The HOX homeodomain proteins block CBP histone acetyltransferase activity - Full text - MIT Libraries
WF Shen, K Krishnan, HJ Lawrence, C Largman - Mol. Cell. Biol, 2001
... Furthermore, a KXKK motif was recently identified as a consensus acetylation
recognition site within the GATA1 protein for the CBP HAT domain (1, 13). ...
Cited by 21 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - dx.doi.org - all 6 versions »

Helix-loop-helix(E 2-5, HEB, TAL 1 and Id 1) protein interaction with the TCRalphadelta enhancers - Full text - MIT Libraries
M Bernard, E Delabesse, L Smit, C Millien, IR … - International Immunology, 1998 - intimm.oupjournals.org
Page 1. International Immunology, Vol. 10, No. 10, pp. 1539–1549 © 1998 Oxford
University Press Helix-loop-helix (E2-5, HEB, TAL1 and Id1) ...
Cited by 6 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

DEA de Genomique et Informatique
S Vonnick - irisa.fr
... 90 t(1 ;19)(q23 ;p13.3) E 2 A-PBX1 5-6 Phénotype pré-B Hyperleucocytose
70-80 ... E 2 A/PBX1 (4 à 5% des LAL de l’enfant) sont ...
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Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels … - Full text - MIT Libraries
DS Chervinsky, XF Zhao, DH Lam, M Ellsworth, KW … - Mol Cell Biol, 1999 - mcb.asm.org
... a pentameric transactivating complex consisting of SCL, E2A, LMO2, GATA1, and LDB1 ...
are reminiscent of those seen with thymocytes from E2A-PBX1 transgenic mice ...
Cited by 34 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Sox4 blocks cytokine-induced differentiation of 32Dcl3 cells and is a possible cooperating partner …
KE Boyd, A Poholek, O Mironenko, NG Copeland, NA … - yalepath.org
... factors (Zfpm1, encoding the GATA1-interacting protein FOG-1; and Tcfec, encoding
the helix-loop-helix protein ... specifically with GATA1 61 . Although ...
View as HTML - Web Search

Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development - Full text - MIT Libraries
DL Mack, DS Leibowitz, S Cooper, H Ramsey, HE … - Immunology, 2002 - blackwell-synergy.com
... of early endothelial and blood differentiation genes like Fli1, Flk1 and Gata1. ... 1;
19) (q23; p13) results in consistent fusion of E2A and PBX1 coding sequences ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Developmental functions of the Distal-less/Dlx homeobox genes - Full text - MIT Libraries
G Panganiban, JL Rubenstein - Development, 2002 - dev.biologists.org
Summary of this Article. Figures Only for this Article. PDF Version of this
Article. Email this article to a friend. Similar articles ...
Cited by 51 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Developmental functions of the Distal-less/Dlx homeobox genes - Full text - MIT Libraries
D DISTAL-LESS - Development, 2002 - ntp.neuroscience.wisc.edu
Page 1. DROSOPHILA DISTAL-LESS Distal-less function Distal-less (Dll), as
its name suggests, is required for distal limb development. ...
View as HTML - Web Search - genetics.wisc.edu

Molecular basis for the inhibition of Drosophila eye development by Antennapedia - Full text - MIT Libraries
S Plaza, F Prince, J Jaeger, U Kloter, S Flister, … - The EMBO Journal, 2001 - embojournal.npgjournals.com
... thereby inhibiting the activity of the transcription factor GATA1 (Rekhtman et ... a
novel nonhomeodomain protein that inhibits the binding of PBX1–HOX complexes ...
Cited by 15 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 7 versions »

TranSignal TM Protein/DNA Arrays
PU Manual, MA MA1014 - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays Cat. # MA1010, MA1011, MA1012 Product User
Manual, MA1013 & MA1014, MA1015 Released 09/28/04 Panomics, Inc. ...
View as HTML - Web Search - biocat.de

Three Genes, Two Species: A Comparative Analysis of Upstream Regulatory Sequences Sufficient to …
M Kirouac, PW Sternberg - etd.caltech.edu
Page 1. Three Genes, Two Species: A Comparative Analysis of Upstream Regulatory
Sequences Sufficient to Direct Vulval Expression in C. elegans and C. briggsae ...
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TranSignal TM Protein/DNA Arrays
CS Version - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays (Column Separation Version) Cat. #
MA1210, MA1211, MA1212l, MA1213 & MA1214, MA1215 Product ...
View as HTML - Web Search

Childhood and Adolescent Lymphoid and Myeloid Leukemia - Full text - MIT Libraries
CH Pui, M Schrappe, RC Ribeiro, CM Niemeyer - Hematology, 2004 - asheducationbook.org
... Although pre-B cell ALL with the t(1;19)/E2A-PBX1 fusion was associated with a poor
prognosis when treatment consisted of standard antimetabolite-based regimens ...
Cited by 1 - Web Search - dx.doi.org - asheducationbook.org - ncbi.nlm.nih.gov

Bibliography Current World Literature
JY Bertrand, S Giroux, R Golub… - Current Opinion in Hematology, 2005 - co-hematology.com
May 2005, 12:3 > Bibliography Current World Literature. ...
Web Search - co-gastroenterology.com - co-ophthalmology.com - coronary-artery.com