Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 … - Full text - MIT Libraries
NR Manley, L Selleri, A Brendolan, J Gordon, ML … - Dev Biol, 2004 - ncbi.nlm.nih.gov
... reported in Hoxa3(-/-) single mutants and Hoxa1(-/-)Hoxb1(-/-) or Hoxa3(+/-)Hoxb3(-/-)
Hoxd3(-/-) compound mutants, suggesting that Pbx1 acts together with ...
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Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in … - Full text - MIT Libraries
PS Knoepfler, KR Calvo, H Chen, SE Antonarakis, MP … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
... and R. Krumlauf Independent regulation of initiation and maintenance phases of Hoxa3
expression in ... S. O'Gorman, and ML Cleary Requirement for Pbx1 in skeletal ...
Cited by 64 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

Independent regulation of initiation and maintenance phases of Hoxa3 expression in the vertebrate … - Full text - MIT Libraries
M Manzanares, S Bel-Vialar, L Ariza-McNaughton, E … - Development, 2001 - dev.biologists.org
Independent regulation of initiation and maintenance phases of Hoxa3 expression
in the vertebrate hindbrain involve auto- and cross-regulatory mechanisms. ...
Cited by 24 - Web Search - caradhras.iib.uam.es - dev.biologists.org - ncbi.nlm.nih.gov

Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and … - Full text - MIT Libraries
L Selleri, MJ Depew, Y Jacobs, SK Chanda, KY Tsang … - Development, 2001 - dev.biologists.org
... contribute to the specification of structures displaying malformations in the Pbx1 -/-
mice (data not shown). These analyses examined Hoxa3 (cervical vertebrae ...
Cited by 27 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Dissertations Summaries
TS Alioto, LTA Clay - dx.doi.org
... We found that Prep1, Pbx1 and Pbx2 are present in the hindbrain at the time ... demonstrated
that r4-specific Hoxb1 and Hoxb2 and r5/r6-specific Hoxa3 en- hancers ...
Web Search - liebertonline.com - liebertonline.com

Rapid Generation of de novo Biological Pathways from Large-Scale Gene Expression Data Using the …
DC Siu - ingenuity.com
... MLL bone marrow sample was analyzed by Ingenuity Pathways Analysis, HOXA9,PBX1,MEIS1,
CD4 ... the networks built using the 100 – gene set,such as HOXA3,PBX3, CD2 ...
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Differences in Gene Expression between Wild Type and Hoxa 1 Knockout Embryonic Stem Cells after … - Full text - MIT Libraries
E Martinez-Ceballos, P Chambon, LJ Gudas - Journal of Biological Chemistry - jbc.org
... inserted into the EcoRI site of pBluescript; a cDNA fragment of Hoxa3 inserted into ...
A Pbx1 cDNA fragment (750 bp) was obtained by restriction digestion of the ...
Web Search - jbc.org - ncbi.nlm.nih.gov

High incidence of proviral integrations in the Hoxa locus in a new model of E 2 a-PBX 1-induced B- … - Full text - MIT Libraries
J Bijl, M Sauvageau, A Thompson, G Sauvageau - Genes & Development, 2005 - genesdev.org
... UTR of Hoxa3 results in the activation of seven genes from Hoxa3 to Hoxa10 ... the
insignificant nature of this particular integration in the absence of E2a–PBX1. ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Homeobox genes and gut development - Full text - MIT Libraries
F Beck, F Tata, K Chawengsaksophak - BioEssays, 2000 - doi.wiley.com
... in mediating proper migration of these organs in the absence of one Hoxa3 allele ...
to the normal expression of the wild-type gene or to the Pbx1 transgene driven ...
Cited by 33 - Web Search - dx.doi.org - gutjnl.com - gut.bmjjournals.com - all 8 versions »

Homeodomain Sequences
SD Subsets, V Plots - pnas.org
... 2, GSCL, Gtx, H6, HB9, HB24, HD1, Hesx1, HEX, HOX11L1, HOX11L2, HOXA1, HOXA2, HOXA3,
HOXA4, HOXA5 ... 6, Og-2, Og-9, Otp, OTX1, OTX2, Pax-3, Pax-7, PBX1, PBX2, PBX3 ...
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Definition of the transcriptional activation domains of three human HOX proteins depends on the DNA- … - Full text - MIT Libraries
MA Vigano, G Di Rocco, V Zappavigna, F Mavilio - Mol. Cell. Biol, 1998 - mcb.asm.org
... B1 chimera, and all the mutants were able to bind cooperatively with PBX1 to the
R3 ... the N terminus in the murine and human group 3 proteins (HOXA3, HOXB3, and ...
Cited by 21 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa 7 and Hoxa 9 - Full text - MIT Libraries
PM Ayton, ML Cleary - Genes & Development, 2003 - genesdev.org
... 3' Hoxa genes were variably expressed with periodicity, as evidenced by low levels
of Hoxa1, higher levels of Hoxa3 and Hoxa5 ... 1992 ) or E2A-PBX1 (Nourse et al. ...
Cited by 27 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Comparative genomics provides evidence for an ancient genome duplication event in sh
JS Taylor, Y Van de Peer, I Braasch, A Meyer - Phil. Trans. R. Soc. Lond. B, 2001 - journals.royalsoc.ac.uk
... In mice, paralogues Hox-1.5 and Hox- 1.6 (renamed HoxA3 and HoxA1 respectivelyöDe
Robertis 1994) have overlapping expression domains and are at least ...
Cited by 102 - Web Search - evolutionsbiologie.uni-konstanz.de - mit.edu - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Molecular Regulation of Muellerian Development by Hox Genes - Full text - MIT Libraries
H DU, HS TAYLOR - Ann. NY Acad. Sci, 2004 - annalsnyas.org
... Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and ... and
distinct roles of kreisler in regulation of the paralogous Hoxa3 and Hoxb3 ...
Cited by 1 - Web Search - dx.doi.org - annalsnyas.org - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... SF1 B SF1 steroidogenic factor 1 Core should be CAAGG not AAGG PBX1 02 Homeo
domain factor Pbx-1 Core should be CAATC not CAAT MAX ...
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Full Article - Full text - MIT Libraries
FR Goodman, PJ Scambler - Clinical Genetics, 2001 - blackwell-synergy.com
... for HOXA13, while his cardiac and velopharyngeal abnormalities resemble those found
in mice homozygous for a targeted deletion in HOXA3 [21], and may well be ...
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Activation of Stem-Cell Specific Genes by HOXA9 and HOXA10 Homeodomain Proteins in CD34 Human Cord …
CM Ferrell, ST Dorsam, H Ohta, RK Humphries, MK … - stemcells.alphamedpress.org
... Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells ... in the
hindbrain: the influence of somite-derived signals, retinoic acid and Hoxa3. ...
Web Search - dx.doi.org - stemcells.alphamedpress.org

Integration of anteroposterior and dorsoventral regulation of Phox 2 b transcription in cranial … - Full text - MIT Libraries
OA Samad, MJ Geisen, G Caronia, I Varlet, V … - Development, 2004 - dev.biologists.org
... 2000 ). Antibodies used are polyclonal anti-Hoxb1 (Babco), polyclonal anti-Pbx1
and anti-Prep1 (Santa Cruz Biotechnology). Immunostaining ...
Cited by 2 - Web Search - biology.mcgill.ca - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Hox Genes and Their Candidate Downstream Targets in the Developing Central Nervous System
ZN Akin, AJ Nazarali - springerlink.com
... Upon binding of DNA by Pbx1 (in the presence or absence of a Hox partner ... group that
has been disrupted (Horan et al., 1995a,b). As an example, Hoxa3, Hoxb3, and ...
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Large-scale reprogramming of cranial neural crest gene expression by retinoic acid exposure - Full text - MIT Libraries
SS Williams, JP Mear, HC Liang, SS Potter, BJ … - Physiological Genomics, 2004 - physiolgenomics.physiology.org
... of the A and B clusters. So too was Pbx1, a cofactor for Hox activity
(46, 66). Other strongly induced transcriptional regulators ...
Cited by 1 - Web Search - physiolgenomics.physiology.org - ncbi.nlm.nih.gov

Conserved and muscle group-specific gene expression patterns shape postnatal development of the … - Full text - MIT Libraries
G Cheng, AP Merriam, B Gong, P Leahy, S Khanna, JD … - Physiological Genomics, 2004 - physiolgenomics.physiology.org
... responsive to retinoic acid (eg, Pax2, 25%; Msx1, 23%; Hoxa3, 21%; Znf42, 19%; Pitx2,
15%; Tfap2a, 10%; Pbx1, 8%; Hnf3b, 6%) also were detected at moderate ...
Web Search - dx.doi.org - ncbi.nlm.nih.gov - ijmm.org - all 5 versions »

The pathophysiology of HOX genes and their role in cancer - Full text - MIT Libraries
DG Grier, A Thompson, A Kwasniewska, GJ McGonigle, … - J Pathol, 2005 - doi.wiley.com
Page 1. Journal of Pathology J Pathol 2005; 205: 154–171 Published online in Wiley
InterScience (www.interscience.wiley.com). DOI: 10.1002/path.1710 ...
Cited by 1 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Functional equivalence of Hox gene products in the specification of the tritocerebrum during … - Full text - MIT Libraries
F Hirth, T Loop, B Egger, DFB Miller, TC Kaufman, … - Development, 2001 - dev.biologists.org
... of recent functional complementation experiments carried out on mammalian
Hoxa3/Hoxd3 genes and ... Structure of a HoxB1-Pbx1 heterodimer bound to DNA: Role of ...
Cited by 8 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Redundant function of Runt Domain binding partners, Big brother and Brother, during Drosophila … - Full text - MIT Libraries
JS Kaminker, R Singh, T Lebestky, H Yan, U … - Development, 2001 - dev.biologists.org
... The paralogs Hoxa3 and Hoxd3 are expressed in the same tissue, but clearly ... The
subcellular localization of PBX1 and EXD proteins depends on nuclear import and ...
Cited by 7 - Web Search - mcdb.ucla.edu - dev.biologists.org - ncbi.nlm.nih.gov

Human Homeobox HOXA 7 Regulates Keratinocyte Transglutaminase Type 1 and Inhibits Differentiation - Full text - MIT Libraries
PT La Celle, RR Polakowska - J Biol Chem, 2001 - jbc.org
... and cooperative DNA binding with either of two homeodomain proteins, PBX1 (34, 35 ...
and overlapping functions have also been observed with Hoxa3, Hoxb3, and Hoxd3 ...
Cited by 9 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Multiple levels of transcriptional and post-transcriptional regulation are required to define the … - Full text - MIT Libraries
T Brend, J Gilthorpe, D Summerbell, PW Rigby - Development, 2003 - dev.biologists.org
... 1998 ), whereas maintenance of r4 expression is dependent on auto-regulation and
cross-regulation by Hoxa1, in association with the cofactor Pbx1 (Pöpperl et ...
Cited by 9 - Web Search - dx.doi.org - dev.biologists.org - ncbi.nlm.nih.gov - all 5 versions »

Specification and Morphogenesis of the Zebrafish Larval Head Skeleton - Full text - MIT Libraries
C Kimmel, CT Miller, CB Moens - Developmental Biology, 2001 - neuro.uoregon.edu
Page 1. Kimmel et al., page 1 Specification and Morphogenesis of the Zebrafish
Larval Head Skeleton Charles B. Kimmel 1,3 , Craig ...
Cited by 26 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Hox in hair growth and development - Full text - MIT Libraries
A Awgulewitsch - Naturwissenschaften, 2003 - springerlink.com
Page 1. Naturwissenschaften (2003) 90:193–211 DOI 10.1007/s00114-003-0417-4 REVIEW
ARTI CLE Alexander Awgulewitsch Hox in hair growth and development ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - adsabs.harvard.edu